Research institution
University Ghent Clinical Trials
Studies where University Ghent is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 55Apical Periodontitis, Post Operative Pain, Acute
Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation
When a tooth's nerve dies, inflammation can develop at the tip of the tooth's root. Root canal treatment is carried out to allow this inflammation to heal.
- Trial name
- NCT07883486
- Testing
- sonically activated irrigation, laser activated irrigation, conventional needle irrigation
- Where
- 2 sites in Belgium
- Volunteers
- 183 people
- Sponsor
- University Ghent
Parkinson Disease (PD), Cognition
Short Term Effects of a Multimodal Intervention With RGM on Cognition in People With Parkinson's Disease.
The goal of this clinical trial is to learn if the Ronnie Gardiner Method (RGM) works to improve cognitive functions in adults with Parkinson's disease (early to mid-stage).
- Conditions
- Parkinson Disease (PD), Cognition, Quality of Life, Functional Mobility
- Trial name
- NCT07863219
- Testing
- Ronnie Gardiner Method
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Ghent
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicide Prevention, User Experience
Evaluation of the Quality of Chat Conversations With the Suicide Helpline Zelfmoordlijn 1813
Suicide remains a serious public health issue in Flanders. Every day, nearly three people die by suicide, and many more attempt it or struggle with suicidal thoughts.
- Conditions
- Suicide Prevention, User Experience, Suicide, Suicidal Ideation
- Trial name
- CHATQ-1813 (NCT07176156)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 373 people
- Sponsor
- University Ghent
Return to Sport, Shoulder Dislocation or Subluxation
Validation of an Upper Extremity Physical Performance Test Battery in Patients After Shoulder Dislocation
The goal of this exploratory prospective study is to determine if an upper extremity test battery, comprised of physical performance tests, analytical tests and patient-reported outcome measures, can predict successful return to…
- Trial name
- VAL_PPT_P (NCT07115225)
- Testing
- Analytical test - Shoulder Range of Motion (ROM), Analytical test - Shoulder Strength, Modified-Athletic Shoulder Test (M-AST)
- Where
- 2 sites in Belgium
- Volunteers
- 129 people
- Sponsor
- University Ghent
Cleft Lip and Palate, Cleft Palate Children
Perceptions of High and Low Intensity Speech Intervention in Children With a Cleft Palate
A cleft (lip and) palate is the most common congenital abnormality of the face and skull with a significant social impact, affecting speech, hearing, feeding, oral behavior, dentition and satisfaction with appearance.
- Conditions
- Cleft Lip and Palate, Cleft Palate Children, Speech Therapy, Speech Disorders in Children
- Trial name
- NCT07781566
- Testing
- High-intensity speech therapy for children with cleft palate, Low-intensity speech therapy for children with cleft palate
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- University Ghent
Speech Therapy, Speech Disorders in Children
High-intensity vs Low-intensity Speech Intervention in Children With Phonological Speech Sound Disorders
Achieving speech that is understandable and acceptable to others is the key outcome in the treatment of phonological speech sound disorders. Therefore, speech therapy provided by a speech-language pathologist is essential.
- Conditions
- Speech Therapy, Speech Disorders in Children, Phonological (Speech) Disorder
- Trial name
- NCT07779759
- Testing
- High-intensity combined phonetic-phonological intervention, Low-intensity combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Ghent
Insulin Resistance, Insulin Resistance and Type 2 Diabetes
The Muscle Monitor: Early Skeletal Muscle Indicators of Insulin Resistance and Cardiometabolic Risk
Insulin resistance is an early etiological factor in the development of type-2 diabetes (T2D), which constitutes a large societal health burden with an expected additional rise in the years to come.
- Conditions
- Insulin Resistance, Insulin Resistance and Type 2 Diabetes, Cardiometabolic Risk Factors, Physical Activity
- Trial name
- MUSCLE MONITOR (NCT07678736)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University Ghent
Suicidal Ideation, Suicide Prevention
User Evaluation Think Life
This study aims to evaluate user experiences with the online self-help course Think Life, a suicide prevention intervention for individuals experiencing suicidal thoughts.
- Conditions
- Suicidal Ideation, Suicide Prevention, mHealth Intervention
- Trial name
- NCT07654127
- Testing
- Self-help course Think Life
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Wound Complication, Wound Care
Using WoundPilot to Support Wound Care Decisions in Patients With Chronic Wounds
This study evaluates whether a digital decision support tool, called WoundPilot, can help primary care nurses make more accurate and consistent decisions when caring for patients with chronic wounds.
- Conditions
- Wound Complication, Wound Care, Wound and Injuries
- Trial name
- NCT07562269
- Testing
- WoundPilot
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Completed, with results posted
All 4Axial Spondyloarthritis
Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation
The hypothesis of the study is that the presence of (subclinical) gut inflammation at baseline in patients with early active axial spondyloarthritis predisposes to a more severe disease defined as more need to use anti-tumor…
- Trial name
- GO-GUT (NCT03270501)
- Testing
- Golimumab
- Where
- 3 sites in Belgium
- Volunteers
- 64 people
- Sponsor
- University Ghent
Voice Disorders
Voice Therapy With a Semi-occluded Vocal Tract
1. The first objective of this research is to investigate the immediate effects of three semi-occluded vocal tract (SOVT) exercises (straw phonation in air, straw phonation in 2cm water, and straw phonation in 5cm water) on…
- Trial name
- NCT06137131
- Testing
- Straw phonation in air, straw phonation in water, /u/ phonation
- Where
- Belgium
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Ghent
Vascular Disease
Transferability and Cost-effectiveness of PROSPECT in Surgical Trainees
To design, validate and prove cost-effectiveness of a comprehensive endovascular simulation curriculum consisting of cognitive and psychomotor skills training for endovascular management of symptomatic vascular disease in the…
- Trial name
- PROSPECT (NCT01965860)
- Testing
- additional curriculum (E-learning + simulation), additional E-learning
- Where
- Belgium
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Ghent
Dietary Modification
Creatine, Carnitine and Carnosine in Vegetarians
Balanced vegetarian diets are popular and contain health-promoting characteristics. A balanced lacto-ovo-vegetarian diet differs in nutrient intake from an omnivorous diet, e.g.
- Trial name
- NCT03194334
- Testing
- Vegetarian diet, creatine, Beta-alanine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent