Canine RetractionDualNCT07508384
Comparison of Maxillary Canine Retraction Rate Among Conventional (Labial) vs Dual (Simultaneous Labial and Palatal) Force Mechanics Using Labial Fixed Orthodontic Appliances
A study testing Dual force application in people with Canine Retraction, run by Dow University of Health Sciences at 1 site in Pakistan.
Trial summary
1. To compare maxillary canine retraction rate among conventional (labial) vs dual (simultaneous labial and palatal) force mechanics using labial fixed orthodontic appliances. 2. To assess the biomechanical effects of dual force vs single force In this study we will be using the most common method i.e. Read more about this study
- Who is it for?
- Ages 15 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Canine Retraction
- What is being tested?
- Dual force application
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 sitePakistan
- Study dates
- 10 Jun 2023to 7 Jun 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 30 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Patients aged 15-30 years.
- Patients undergoing conventional labial fixed appliance treatment.
- Good oral hygiene and periodontal support.
- Patients with maxillary first premolar's extraction treatment plan.
Who cannot join
- Patients with buccally displaced, high, missing or impacted canines.
- Systemic diseases like diabetes, hypertension etc
- Any bone pathology or taking medicines like bisphosphonates which slow down tooth movement.
- Patients with narrow/constricted maxillary arches
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Dr Ishrat ul Ebad Khan Institute of Oral Health Sciences
Karachi, 75300
About this study
- To compare maxillary canine retraction rate among conventional (labial) vs dual (simultaneous labial and palatal) force mechanics using labial fixed orthodontic appliances.
- To assess the biomechanical effects of dual force vs single force In this study we will be using the most common method i.e. labial fixed appliances with different techniques to find a more faster and controlled method of canine retraction with least undesirable movements.
Lingual appliances are difficult to apply in normal practice but it has many advantages like faster movement of teeth, less anchorage loss so by using dual force we will have advantages of lingual appliance in combination with the conventional labial technique.
Read the detailed description
This split mouth study was conducted on 45 patients in which extraction of maxillary first premolars is their orthodontic treatment plan. Patient's maxillary arch was randomly subdivided (through chit method) into control and experimental groups. Labial fixed orthodontic appliances were used in all patients included. GROUP 1 includes canine retraction through conventional (labial) force. GROUP 2 includes canine retraction through dual (labial as well as palatal) force. Critical anchorage was used. Rate of canine retraction was measured through Vernier calipers intraorally as well as on study casts at following time points. T0: just before canine retraction. T1-T6: 1-6 months of canine retraction.
- Conditions
- Canine Retraction
- Being tested
- Dual force application
- Keywords
- Canine retraction, Dual force
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dual force applicationProcedure or surgery
Also called Canine retraction
Dual force is applied on one side and compared with conventional retraction
| Study group | Role | What they receive |
|---|---|---|
| Labial force vs dual retraction force | Experimental | Rate of canine retraction was measured among labial vs dual force for retraction Receives: Procedure: Dual force application |
| Dual force | Experimental | On one side canine retraction is done with labial force only while on other side dual force i.e labial as well as palatal forces are used Receives: Procedure: Dual force application |
What is being measured
The primary outcome is the main question the study is designed to answer.
To compare maxillary canine retraction rate among conventional (labial) vs dual (simultaneous labial and palatal) force mechanics using labial fixed orthodontic appliances.
Rate of canine retraction will be assessed and compared from T1 to T6 in two groups one with labial force only and the other with dual force through measurement taken on cast as well as intraorally at each timepoints through vernier calipers.
Measured: 6 months
Secondary outcomes (1)
. To assess the biomechanical effects of dual force vs single force
During canine retraction biomechaical effects will be assessed that most commonly occur such as rotation in dual force vs conventional single force through measurement from the cast duplicated on tracing paper to evaluate mesial and distal angle of canine.
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Apr 2026
- Study start10 Jun 2023
- Primary completion23 Mar 2024
- Study completion7 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Canine RetractionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 45 participants (actual)
Sponsor and investigators
- Lead sponsor
- Dow University of Health Sciences
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07508384
- Sponsor's protocol ID
- 2990
- Acronym
- Dual
- Status last verified
- Feb 2026
- First submitted
- 28 Feb 2026
- Last updated
- 2 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Anis B, Rizwan S, Zehra S, Sattar A, Arsalan M, Nasir L. Comparison of Maxillary Canine Retraction Rate Among Conventional (Labial) vs. Dual (Simultaneous Labial and Palatal) Mechanics During Fixed Orthodontic Treatment-A Randomised Controlled Trial. Orthod Craniofac Res. 2026 Nov 3. doi: 10.1111/ocr.70198. Online ahead of print.
PubMed 42978198
Study at a glance
From the registry record, last updated by the sponsor on 2 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Maxillary Canine Retraction Rate Among Conventional (Labial) vs Dual (Simultaneous Labial and Palatal) Force Mechanics Using Labial Fixed Orthodontic Appliances
- ClinicalTrials.gov ID
- NCT07508384
- Acronym / sponsor ID
- Dual / 2990
- Conditions
- Canine Retraction
- Keywords
- Canine retraction, Dual force
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 45 participants (actual)
- Lead sponsor
- Dow University of Health SciencesUniversity, hospital or other
- Study start
- 10 Jun 2023 (actual)
- Primary completion
- 23 Mar 2024 (actual)
- Study completion
- 7 Jun 2024 (actual)
- First posted
- 2 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
- To compare maxillary canine retraction rate among conventional (labial) vs dual (simultaneous labial and palatal) force mechanics using labial fixed orthodontic appliances.
- To assess the biomechanical effects of dual force vs single force In this study we will be using the most common method i.e. labial fixed appliances with different techniques to find a more faster and controlled method of canine retraction with least undesirable movements.
Lingual appliances are difficult to apply in normal practice but it has many advantages like faster movement of teeth, less anchorage loss so by using dual force we will have advantages of lingual appliance in combination with the conventional labial technique.
Detailed description
This split mouth study was conducted on 45 patients in which extraction of maxillary first premolars is their orthodontic treatment plan. Patient's maxillary arch was randomly subdivided (through chit method) into control and experimental groups. Labial fixed orthodontic appliances were used in all patients included. GROUP 1 includes canine retraction through conventional (labial) force. GROUP 2 includes canine retraction through dual (labial as well as palatal) force. Critical anchorage was used. Rate of canine retraction was measured through Vernier calipers intraorally as well as on study casts at following time points. T0: just before canine retraction. T1-T6: 1-6 months of canine retraction.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Labial force vs dual retraction force | Experimental | Procedure: Dual force applicationRate of canine retraction was measured among labial vs dual force for retraction |
| Dual force | Experimental | Procedure: Dual force applicationOn one side canine retraction is done with labial force only while on other side dual force i.e labial as well as palatal forces are used |
Who may qualify
- Ages
- 15 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (4 listed)
- Patients aged 15-30 years.
- Patients undergoing conventional labial fixed appliance treatment.
- Good oral hygiene and periodontal support.
- Patients with maxillary first premolar's extraction treatment plan.
Key exclusion criteria (4 listed)
- Patients with buccally displaced, high, missing or impacted canines.
- Systemic diseases like diabetes, hypertension etc
- Any bone pathology or taking medicines like bisphosphonates which slow down tooth movement.
- Patients with narrow/constricted maxillary arches
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dual force applicationAlso: Canine retractionDual force is applied on one side and compared with conventional retraction | Procedure or surgery | Dual force, Labial force vs dual retraction force |
Primary outcome
To compare maxillary canine retraction rate among conventional (labial) vs dual (simultaneous labial and palatal) force mechanics using labial fixed orthodontic appliances.
Time frame: 6 months
Rate of canine retraction will be assessed and compared from T1 to T6 in two groups one with labial force only and the other with dual force through measurement taken on cast as well as intraorally at each timepoints through vernier calipers.
1 secondary outcome
. To assess the biomechanical effects of dual force vs single force
Time frame: 6 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Apr 2026.
- Derived from this study: PubMed 42978198Anis B, Rizwan S, Zehra S, Sattar A, Arsalan M, Nasir L. Comparison of Maxillary Canine Retraction Rate Among Conventional (Labial) vs. Dual (Simultaneous Labial and Palatal) Mechanics During Fixed Orthodontic Treatment-A Randomised Controlled Trial. Orthod Craniofac Res. 2026 Nov 3. doi: 10.1111/ocr.70198. Online ahead of print.
- Individual participant dataSharing planned: No
Related trials for Canine Retraction
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Discision as Acceleration Method in Canine Retraction in Orthodontics With Aligner and Fixed Appliances in Young Adults a Split Mouth Study
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Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction
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Enrolling by invitation
Evaluation of Corticotomy-Assisted Canine Retraction Rate
Malocclusion, Corticotomy
Recruiting
Accelerated Orthodontics With Alveolar Decortication Plus CGF Injection
Accelerate Tooth Movement
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Comparison of Maxillary Canine Retraction Rate With and Without Power Arm
Orthodontic Anchorage, Power Arm Sliding
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Dual force application in people with Canine Retraction, run by Dow University of Health Sciences at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To compare maxillary canine retraction rate among conventional (labial) vs dual (simultaneous labial and palatal) force mechanics using labial fixed orthodontic appliances. (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07508384, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Apr 2026.