Bimaxillary ProtrusionNCT07920276
Discision as Acceleration Method in Canine Retraction in Orthodontics With Aligner and Fixed Appliances in Young Adults a Split Mouth Study
A study testing Discision in people with Bimaxillary Protrusion and Class II Div 1 Malocclusion, run by Al-Azhar University at 2 sites in Egypt.
Trial summary
The effectiveness of discision in accelerating orthodontic canine retraction will be evaluated during clear aligner therapy and during conventional fixed orthodontic appliances. Furthermore, the effectiveness of clear aligner therapy in achieving orthodontic canine retraction will be assessed. Read more about this study
- Who is it for?
- Ages 17 to 24 yearsHealthy volunteers can take part
- Conditions the study is for
- Bimaxillary Protrusion, Class II Div 1 Malocclusion
- What is being tested?
- Discision
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 24 participants
- Where
- 2 sitesEgypt
- Study dates
- 1 Feb 2026to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 17 to 24 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- 1 - Age from 17 to 24 years old. 2- Fully erupted permanent dentition, 3rd molars excluded. 3- Patients need 1st premolars extraction therapy to achieve class I canine relationship e.g. class I bimaxillary dentoaveolar protrusion or class II division 1 malocclusion with mild or no crowding.
- 4- Normal shape and structure of maxillary canines, with no history of filling or root canal treatment.
- 5- Similar degree of minimal crowding on each side of the maxillary arch. 6- Good oral and general health.
Who cannot join
- Impacted canine.
- Systemic disease or medications affect bone quality or orthodontic tooth movement.
- Craniofacial anomalies, Cleft lip/palate.
- lateral open bite or posterior cross bite.
- Poor oral hygiene or periodontally compromised patient
- History of previous orthodontic treatment
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt2 sites
Faculty of dental medicine, Al-Azhar University, Boys, Cairo
Naşr, Cairo Governorate
Faculty of dental medicine,Al-Azhar University,Boys,Cairo
Naşr, Cairo Governorate
About this study
Official title: Evaluation of Maxillary Canine Retraction With Discision Facilitated Method in Young Adults With Clear Aligner Versus Those With Fixed Appliance: (A Split-mouth Comparative Randomized Clinical and Radiographic Study)
The effectiveness of discision in accelerating orthodontic canine retraction will be evaluated during clear aligner therapy and during conventional fixed orthodontic appliances.
Furthermore, the effectiveness of clear aligner therapy in achieving orthodontic canine retraction will be assessed.
Read the detailed description
Discision means using a disk to cut through the cortical bone inducing regional acceleratory phenomenon (RAP) which may accelerate orthodontic tooth movement (OTM).
- Being tested
- Discision
- Keywords
- Canine retraction, Fixed appliances, Clear aligners, Acceleration of orthodontic tooth movement, Discision
- Medical subject headings
- Malocclusion, Angle Class II
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
DiscisionProcedure or surgery
Using a disk saw to make cut it the bone mesial and distal to the canine in one side randomly to accelerate it's movement (retraction).
| Study group | Role | What they receive |
|---|---|---|
| Group 1. Patients will be treated with clear aligner | Experimental | Divided into: Two subgroups by split mouth right and left side randomly. One side with discision and other without. Receives: Procedure: Discision |
| Group 2. Patients will be treated with fixed appliances | Experimental | Divided into: Two subgroups by split mouth right and left side randomly. One side with discision and other side without Receives: Procedure: Discision |
What is being measured
The primary outcome is the main question the study is designed to answer.
Evaluation of maxillary canine retraction rate in millimeters per week
Evaluation of maxillary canine retraction with discision in clear aligners verses fixed appliances using cbct
Measured: 10 weeks from the beginning of canine retraction.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Nov 2026
- Study start1 Feb 2026
- Primary completionNov 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Bimaxillary ProtrusionStudies of the same condition, open and under way.
- More trials run by Al-Azhar UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 24 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Al-Azhar University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Abd Elrahman Ahmed Selim, Al-Azhar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07920276
- Sponsor's protocol ID
- 1092/4493
- Status last verified
- Nov 2026
- First submitted
- 5 May 2026
- Last updated
- 5 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 5 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Maxillary Canine Retraction With Discision Facilitated Method in Young Adults With Clear Aligner Versus Those With Fixed Appliance: (A Split-mouth Comparative Randomized Clinical and Radiographic Study)
- ClinicalTrials.gov ID
- NCT07920276
- Acronym / sponsor ID
- 1092/4493
- Keywords
- Canine retraction, Fixed appliances, Clear aligners, Acceleration of orthodontic tooth movement, Discision
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 24 participants (estimated)
- Lead sponsor
- Al-Azhar UniversityUniversity, hospital or other
- Study start
- 1 Feb 2026 (actual)
- Primary completion
- Nov 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 5 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The effectiveness of discision in accelerating orthodontic canine retraction will be evaluated during clear aligner therapy and during conventional fixed orthodontic appliances.
Furthermore, the effectiveness of clear aligner therapy in achieving orthodontic canine retraction will be assessed.
Detailed description
Discision means using a disk to cut through the cortical bone inducing regional acceleratory phenomenon (RAP) which may accelerate orthodontic tooth movement (OTM).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group 1. Patients will be treated with clear aligner | Experimental | Procedure: DiscisionDivided into: Two subgroups by split mouth right and left side randomly. One side with discision and other without. |
| Group 2. Patients will be treated with fixed appliances | Experimental | Procedure: DiscisionDivided into: Two subgroups by split mouth right and left side randomly. One side with discision and other side without |
Who may qualify
- Ages
- 17 to 24 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- 1 - Age from 17 to 24 years old. 2- Fully erupted permanent dentition, 3rd molars excluded. 3- Patients need 1st premolars extraction therapy to achieve class I canine relationship e.g. class I bimaxillary dentoaveolar protrusion or class II division 1 malocclusion with mild or no crowding.
- 4- Normal shape and structure of maxillary canines, with no history of filling or root canal treatment.
- 5- Similar degree of minimal crowding on each side of the maxillary arch. 6- Good oral and general health.
Key exclusion criteria (6 listed)
- Impacted canine.
- Systemic disease or medications affect bone quality or orthodontic tooth movement.
- Craniofacial anomalies, Cleft lip/palate.
- lateral open bite or posterior cross bite.
- Poor oral hygiene or periodontally compromised patient
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| DiscisionUsing a disk saw to make cut it the bone mesial and distal to the canine in one side randomly to accelerate it's movement (retraction). | Procedure or surgery | Group 1. Patients will be treated with clear aligner, Group 2. Patients will be treated with fixed appliances |
Primary outcome
Evaluation of maxillary canine retraction rate in millimeters per week
Time frame: 10 weeks from the beginning of canine retraction.
Evaluation of maxillary canine retraction with discision in clear aligners verses fixed appliances using cbct
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Nov 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Discision in people with Bimaxillary Protrusion and Class II Div 1 Malocclusion, run by Al-Azhar University at 2 sites in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 5 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evaluation of maxillary canine retraction rate in millimeters per week (time frame: 10 weeks from the beginning of canine retraction.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Nov 2026.