Neurofilament Light ChainNCT07312994
Analysis of NfL and GFAP in Different Dietary Patterns
An observational study of Neurofilament Light Chain and Glial Fibrillary Acidic Protein, run by Salzburger Landeskliniken at 1 site in Austria.
Trial summary
This observational study aims to investigate the impact of different dietary patterns on brain tissue biomarkers in healthy young adults by measuring blood levels of NfL and GFAP. The primary research question is: Do vegan, vegetarian, or omnivorous diets influence NfL and GFAP levels? Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Neurofilament Light Chain, Glial Fibrillary Acidic Protein, GFAP
- How many people
- 300 participants
- Where
- 1 siteAustria
- Study dates
- 18 Dec 2025to Sep 2026
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Young and healthy individuals aged between 18 and 40 years
Who may be able to join
- Healthy individuals who have followed a vegan, vegetarian, or omnivorous diet for at least one consecutive year
- Aged between 18 and 40 years
- Provision of written informed consent
Who cannot join
- Diagnose neurological disorders (e.g. neurodegenerative, inflammatory, autoimmune, infectious, vascular)
- Eating disorders
- Excessive alcohol consumption
- Pregnancy
- Recent moderate to severe infection (within the past 12 weeks) , including SARS-CoV-2
- Recent trauma, injury, or surgery (within the past 12 weeks)
- Significant BMI fluctuations (>5 points) within the last year
- Patients who have been using Proton pump inhibitors (PPIs) for an extended period (e.g., 1 month).
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Austria1 site, 1 recruiting
- Recruiting
Christian-Doppler-Klinik
Salzburg, State of Salzburg, 5020
Fabio Rossini, MD, f.rossin@salk.at
About this study
Official title: Vegan, Vegeratian, or Omnivore: Dietary Effects on the Brain Tissue Biomarkers
This observational study aims to investigate the impact of different dietary patterns on brain tissue biomarkers in healthy young adults by measuring blood levels of NfL and GFAP.
The primary research question is: Do vegan, vegetarian, or omnivorous diets influence NfL and GFAP levels?
- Conditions
- Neurofilament Light Chain, Glial Fibrillary Acidic Protein, GFAP, Vegan Diet, Vegetarian Diet
- Medical subject headings
- Charcot-Marie-Tooth disease, Type 1F
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Omnivore | Not described | |
| Vegan | Not described | |
| Vegetarian | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Blood levels of the following biomarkers: neurofilament light chain (NfL) in pg/mL, glial fibrillary acidic protein (GFAP) in pg/mL.
Measured: Once at baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Dec 2025
- Study start18 Dec 2025
- Primary completionApr 2026 (estimated)
- Study completionSep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neurofilament Light ChainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 300 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Salzburger Landeskliniken
- Sponsor type
- University, hospital or other
- Collaborators
- Medizinische Einrichtungen der Universität Düsseldorf, Universität zu Köln, Universitätsklinkum Münster - Medizinische Klinik und Poliklinik B
- Responsible party
- Principal investigator, Tobias Moser, Salzburger Landeskliniken
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07312994
- Sponsor's protocol ID
- 1119/2025
- Status last verified
- Dec 2025
- First submitted
- 9 Dec 2025
- Last updated
- 31 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No