Exercise TrainingNCT07261553
Adherence to Home-Based Exercises in Musculoskeletal Disorders
An observational study of Exercise Training and Adherence, Treatment, run by Konya Beyhekim Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
Home exercise program is recommended by physicians to patients and their relatives to do at home and It is a treatment option in which the physician describes how to do it. Home workout program to be completed at home to complement and reinforce their program in the clinic It is a personalized set of therapeutic… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Exercise Training, Adherence, Treatment, Musculoskeletal Disease
- What is being tested?
- Home exercise program
- How many people
- 252 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 30 Dec 2024to 15 May 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: * Be 18 years of age or older * To have a musculoskeletal disease (degenerative, neurological or orthopedic) * To be given a home exercise program * To have cognitive and language functions to communicate, to be a volunteer
Who may be able to join
- Be 18 years of age or older
- To have a musculoskeletal disease (degenerative, neurological or orthopedic)
- To be given a home exercise program
- To have cognitive and language functions to communicate, to be a volunteer
Who cannot join
- Those with major psychiatric illness
- Those with cognitive dysfunction
- Those with communication disorders, reluctant/reluctant to participate
- Those with any condition other than a primary degenerative, orthopedic, or neurological disease that could significantly affect exercise adherence, including musculoskeletal or systemic disorders (e.g., severe anemia, heart failure, respiratory failure, uncontrolled diabetes, inflammatory rheumatic disease, recent fractures, or active infections).
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
ramazan Yılmaz, assoc prof contact
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
University of Health Sciences, Konya Beyhekim Training and Research Hospital, Department of Physical Medicine and Rehabilitation, Konya, Turkey 42060
Konya, Konya, 42080
Merve Albayrak, Dr., +905067368102, mervealbyrak20z@gmail.com
Ramazan Yılmaz, Assoc Prof, drramazanyilmaz@yahoo.com
About this study
Official title: Adherence to Home-Based Exercise Programs Among Patients With Musculoskeletal Disorders and Its Influencing Factors
Home exercise program is recommended by physicians to patients and their relatives to do at home and It is a treatment option in which the physician describes how to do it. Home workout program to be completed at home to complement and reinforce their program in the clinic It is a personalized set of therapeutic exercises that are taught. There are factors that can change exercise compliance; There are some reasons why some patients adhere to the prescribed home exercise program and others do not.
Adherence to home exercises is a major issue in rehabilitation and the reasons for this are multifactorial; It includes both psychological and specific conditions factors that vary between each individual and these conditions should be taken into account by clinicians in designing personalized exercise programs.
Read more
Home exercise programs constitute a fundamental component of rehabilitation and are widely prescribed by physicians support therapeutic gains beyond the clinical environment. These individualized programs aim to maintain functional improvements, reduce symptoms, and promote self-management among individuals with musculoskeletal disorders. Although adherence to home-based exercises is recognized as a key determinant of rehabilitation outcomes, non-adherence remains a persistent challenge. Despite growing emphasis on the importance of exercise compliance, the existing literature provides relatively limited and insufficient evidence regarding the factors that influence adherence across different musculoskeletal conditions, including degenerative, orthopedic, and neurological disorders.
Addressing this gap, the present prospective longitudinal cohort study aims to evaluate adherence to individualized home-based exercise programs among patients with diverse musculoskeletal conditions and to determine whether adherence behaviors differ across diagnostic groups. In addition, the study seeks to identify demographic, clinical, psychosocial, and functional factors associated with exercise compliance. By integrating structured clinical evaluations with validated outcome measures, this study aims not only to clarify the determinants of exercise adherence but also to contribute to the development of more effective, condition-specific strategies to enhance sustained engagement in home-based rehabilitation.
Read the detailed description
Home exercise programs are recommended by physicians to patients and when appropriate, their caregivers as interventions to be performed outside the clinical setting. In this treatment approach, the physician provides detailed instructions on how the exercises should be carried out. These programs consist of individualized therapeutic exercises designed to be performed at home, with the aim of complementing and reinforcing the interventions delivered in the clinic. Addressing this gap, the present study aims to evaluate adherence to individualized home-based exercise programs among patients with diverse musculoskeletal conditions and to determine whether adherence behaviors differ across diagnostic groups. In addition, the study seeks to identify demographic, clinical, psychosocial, and functional factors associated with exercise compliance. By integrating structured clinical evaluations with validated outcome measures, this study aims not only to clarify the determinants of exercise adherence but also to contribute to the development of more effective, condition-specific strategies to enhance sustained engagement in home-based rehabilitation.
Meeting the inclusion and exclusion criteria; various musculoskeletal diseases; Patients presenting for degenerative, orthopedic or neurological rehabilitation will be included in the study by obtaining written informed consent after an individualized home exercise program after a detailed clinical examination.
Questions such as age, gender, height, weight, education level, employment status, income level and sociodemographic and clinical characteristics of the participants (diagnosis of the disease, duration, comorbidity/cumulative disease score status, medical treatment status, if any, pain/weakness level, functional status) will be recorded.
All patients will receive an individualized home exercise program based on their clinical condition. Exercises will be determined by the physical therapy and rehabilitation physician, taking into account the minimum clinical needs and individual characteristics of the patient. People receiving active physical therapy; will not be included in the study. In terms of content, general physical therapy will consist of exercises, not specific exercises that are rarely practiced or performed by a health professional. The number of sets of exercises per day, how many times they will be done in each set and how many days a week will be defined and recorded. The exercises will be explained to the patient by the physician and the printed paper describing these exercises will be given to the patient.
Three condition-specific subcohorts will be defined: chronic degenerative, orthopedic (post-operative) and neurological patients. Patients in the degenerative, orthopedic, or neurological rehabilitation groups will be provided with a patient-specific home exercise program, and their adherence and adaptations to the program will be evaluated and compared. Patients will do the home-based exercise program for 6 weeks. Patients will undergo both clinical and outcome-based assessments at baseline and again at the completion of the home exercise program (6 weeks).
Among the result criteria; Primary variables; Beck Depression Index (BDI) for mood, Health Assessment Questionnaire (HAQ) for quality of life, Kinesiophobia assessment; Tampa Kinesiophobia Scale, Visual Analog Scale (VAS 0-10), for Activities of Daily Living; Barthel Activities of Daily Living Index Secondary variables; to assess how an individual's health condition affects their daily life for exercise adherence; The Exercise Adherence Rating Scale/Exercise Attitude Questionnarie. All assessments will be evaluated by a group-blind investigator after 6 weeks with clinical examination and a set of evaluation scales/questionnaires. The patients' clinical status, satisfactions, their adherence to exercise therapy, and the factors influencing this adherence will be evaluated. Patients whose diagnosis was established after a detailed examination and for whom an exercise program was prescribed will be included in the study. The decision will be based solely on the patient's ability to perform the exercises and adherence to the inclusion and exclusion criteria. Other factors that could potentially introduce bias, such as education level or the patient's willingness to exercise, will not be considered in determining treatment, in order to minimize selection bias. Patients will be instructed not to take any analgesics within 24 hours prior to the assessment.
- Conditions
- Exercise Training, Adherence, Treatment, Musculoskeletal Disease, Rehabilitation Exercise, Adherence, Patient, Home Exercise Program
- Being tested
- Home exercise program
- Keywords
- Home Exercise Program, adherence, Rehabilitation Exercise, Musculoskeletal Disease, Adherence, Patient
- Medical subject headings
- Treatment Adherence and Compliance, Musculoskeletal Diseases, Patient Compliance, Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Home exercise programOther
Patients with chronic degenerative musculoskeletal disorders receiving a home exercise program
Home exercise programOther
Patients receiving a home exercise program as part of post-operative orthopedic rehabilitation
Home exercise programOther
Patients receiving a home exercise program following a neurological condition (stroke,hemiplegia) as part of rehabilitation
| Study group | Role | What they receive |
|---|---|---|
| Degenerative rehabilitation | Patients with chronic degenerative musculoskeletal disorders, including nonspecific low back pain, chronic nonspecific neck pain, and knee osteoarthritis, receiving a home-based exercise program (subcohort) Receives: Other: Home exercise program | |
| Orthopedic rehabilitation | Patients receiving a home exercise program as part of post-operative orthopedic rehabilitation, including rehabilitation following rotator cuff repair, total knee arthroplasty, and lumbar spinal surgery (subcohort). Receives: Other: Home exercise program | |
| Neurological | Patients receiving a home-based exercise program following a neurological condition (stroke, hemiplegia) as part of neurological rehabilitation (subcohort). Receives: Other: Home exercise program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Exercise Adherence Rating Scale
It was developed to evaluate compliance with home exercise programs. The first part (Group A) contains the participant's general information about the exercise program; the second part (Group B; 0-24 points) examines the frequency and sustainability of exercise behaviors; the third part (Group C; 0-40 points) evaluates cognitive and environmental factors affecting exercise adherence. The total score ranges from 0-64, with higher scores indicating greater compliance. The Turkish adaptation, including validation and reliability analysis, was conducted in 2019.
Measured: 6th week
Secondary outcomes (5)
VAS
VAS ; patients were asked to mark their pain intensity pain activity and rest: 0 no pain; 10 Unbearable/Max. Pain.
Ranges for the severity of pain and weakness; <3 mild, 3-6 moderate, >6 severe.
Measured: Baseline and 6th week
Beck Depression Index
BDI consists of 21 items related to depressive symptoms such as pessimism, sense of failure, dissatisfaction, feelings of guilt, restlessness, fatigue, decreased appetite, indecision, sleep disturbance, and social withdrawal. Each item contains four levels (0-3) self-evaluation statements that determine a behavior specific to depression . The total maximum score was 63, and a score above 17 indicates an increased risk of depressive states.
Measured: Baseline and 6th week
Barthel Index
Barthel Index is a general scale developed for independence in activities of daily living. It consists of 10 questions. In the scoring ranging from 0-100 points, 100; best complete independence, 0; the worst refers to absolute dependence.
Measured: Baseline ve 6th week
Tampa Kinesiophobia Scale
Tampa Kinesiophobia Scale ; is a 17-question scale developed to measure the fear of movement/re-injury. The scale includes parameters for injury/re-injury and fear-avoidance in work-related activities. A 4-point Likert scoring (1= Strongly disagree, 4= Completely agree) is used in the scale. A total score is calculated after reversing items 4, 8, 12 and 16. The person gets a total score between 17-68. The higher the score of the person on the scale, indicates that kinesiophobia is also high.
Measured: Baseline and 6th week
Health assessment questionnaire
Health assessment questionnaire (HAQ) is the most widely used disease-related, short, easy-to-apply quality of life scale used in clinical research. The scale consists of a total of 21 questions in 8 sub-headings. Each question has a likert type option ranging from 0-3 points. The total score ranges from 0-63. High scores indicate poor (dependent) health.
Measured: Baseline and 6th week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Dec 2025
- Study start30 Dec 2024
- Primary completion1 Apr 2026 (estimated)
- Study completion15 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Exercise TrainingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 252 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Konya Beyhekim Training and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Merve Albayrak, Konya Beyhekim Training and Research Hospital
- Investigators
- Ramazan Yilmaz, Study chair, Konya Beyhekim Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07261553
- Sponsor's protocol ID
- BeyhekimTRHMA2025
- Status last verified
- Mar 2026
- First submitted
- 22 Nov 2025
- Last updated
- 25 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Adherence to Home-Based Exercise Programs Among Patients With Musculoskeletal Disorders and Its Influencing Factors
- ClinicalTrials.gov ID
- NCT07261553
- Acronym / sponsor ID
- BeyhekimTRHMA2025
- Conditions
- Exercise Training, Adherence, Treatment, Musculoskeletal Disease, Rehabilitation Exercise, Adherence, Patient, Home Exercise Program
- Keywords
- Home Exercise Program, adherence, Rehabilitation Exercise, Musculoskeletal Disease, Adherence, Patient
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 252 participants (estimated)
- Lead sponsor
- Konya Beyhekim Training and Research HospitalOther government
- Study start
- 30 Dec 2024 (actual)
- Primary completion
- 1 Apr 2026 (estimated)
- Study completion
- 15 May 2026 (estimated)
- First posted
- 3 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Home exercise program is recommended by physicians to patients and their relatives to do at home and It is a treatment option in which the physician describes how to do it. Home workout program to be completed at home to complement and reinforce their program in the clinic It is a personalized set of therapeutic exercises that are taught. There are factors that can change exercise compliance; There are some reasons why some patients adhere to the prescribed home exercise program and others do not.
Adherence to home exercises is a major issue in rehabilitation and the reasons for this are multifactorial; It includes both psychological and specific conditions factors that vary between each individual and these conditions should be taken into account by clinicians in designing personalized exercise programs.
Home exercise programs constitute a fundamental component of rehabilitation and are widely prescribed by physicians support therapeutic gains beyond the clinical environment. These individualized programs aim to maintain functional improvements, reduce symptoms, and promote self-management among individuals with musculoskeletal disorders. Although adherence to home-based exercises is recognized as a key determinant of rehabilitation outcomes, non-adherence remains a persistent challenge. Despite growing emphasis on the importance of exercise compliance, the existing literature provides relatively limited and insufficient evidence regarding the factors that influence adherence across different musculoskeletal conditions, including degenerative, orthopedic, and neurological disorders.
Addressing this gap, the present prospective longitudinal cohort study aims to evaluate adherence to individualized home-based exercise programs among patients with diverse musculoskeletal conditions and to determine whether adherence behaviors differ across diagnostic groups. In addition, the study seeks to identify demographic, clinical, psychosocial, and functional factors associated with exercise compliance. By integrating structured clinical evaluations with validated outcome measures, this study aims not only to clarify the determinants of exercise adherence but also to contribute to the development of more effective, condition-specific strategies to enhance sustained engagement in home-based rehabilitation.
Detailed description
Home exercise programs are recommended by physicians to patients and when appropriate, their caregivers as interventions to be performed outside the clinical setting. In this treatment approach, the physician provides detailed instructions on how the exercises should be carried out. These programs consist of individualized therapeutic exercises designed to be performed at home, with the aim of complementing and reinforcing the interventions delivered in the clinic. Addressing this gap, the present study aims to evaluate adherence to individualized home-based exercise programs among patients with diverse musculoskeletal conditions and to determine whether adherence behaviors differ across diagnostic groups. In addition, the study seeks to identify demographic, clinical, psychosocial, and functional factors associated with exercise compliance. By integrating structured clinical evaluations with validated outcome measures, this study aims not only to clarify the determinants of exercise adherence but also to contribute to the development of more effective, condition-specific strategies to enhance sustained engagement in home-based rehabilitation.
Meeting the inclusion and exclusion criteria; various musculoskeletal diseases; Patients presenting for degenerative, orthopedic or neurological rehabilitation will be included in the study by obtaining written informed consent after an individualized home exercise program after a detailed clinical examination.
Questions such as age, gender, height, weight, education level, employment status, income level and sociodemographic and clinical characteristics of the participants (diagnosis of the disease, duration, comorbidity/cumulative disease score status, medical treatment status, if any, pain/weakness level, functional status) will be recorded.
All patients will receive an individualized home exercise program based on their clinical condition. Exercises will be determined by the physical therapy and rehabilitation physician, taking into account the minimum clinical needs and individual characteristics of the patient. People receiving active physical therapy; will not be included in the study. In terms of content, general physical therapy will consist of exercises, not specific exercises that are rarely practiced or performed by a health professional. The number of sets of exercises per day, how many times they will be done in each set and how many days a week will be defined and recorded. The exercises will be explained to the patient by the physician and the printed paper describing these exercises will be given to the patient.
Three condition-specific subcohorts will be defined: chronic degenerative, orthopedic (post-operative) and neurological patients. Patients in the degenerative, orthopedic, or neurological rehabilitation groups will be provided with a patient-specific home exercise program, and their adherence and adaptations to the program will be evaluated and compared. Patients will do the home-based exercise program for 6 weeks. Patients will undergo both clinical and outcome-based assessments at baseline and again at the completion of the home exercise program (6 weeks).
Among the result criteria; Primary variables; Beck Depression Index (BDI) for mood, Health Assessment Questionnaire (HAQ) for quality of life, Kinesiophobia assessment; Tampa Kinesiophobia Scale, Visual Analog Scale (VAS 0-10), for Activities of Daily Living; Barthel Activities of Daily Living Index Secondary variables; to assess how an individual's health condition affects their daily life for exercise adherence; The Exercise Adherence Rating Scale/Exercise Attitude Questionnarie. All assessments will be evaluated by a group-blind investigator after 6 weeks with clinical examination and a set of evaluation scales/questionnaires. The patients' clinical status, satisfactions, their adherence to exercise therapy, and the factors influencing this adherence will be evaluated. Patients whose diagnosis was established after a detailed examination and for whom an exercise program was prescribed will be included in the study. The decision will be based solely on the patient's ability to perform the exercises and adherence to the inclusion and exclusion criteria. Other factors that could potentially introduce bias, such as education level or the patient's willingness to exercise, will not be considered in determining treatment, in order to minimize selection bias. Patients will be instructed not to take any analgesics within 24 hours prior to the assessment.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Degenerative rehabilitation | – | Other: Home exercise programPatients with chronic degenerative musculoskeletal disorders, including nonspecific low back pain, chronic nonspecific neck pain, and knee osteoarthritis, receiving a home-based exercise program (subcohort) |
| Orthopedic rehabilitation | – | Other: Home exercise programPatients receiving a home exercise program as part of post-operative orthopedic rehabilitation, including rehabilitation following rotator cuff repair, total knee arthroplasty, and lumbar spinal surgery (subcohort). |
| Neurological | – | Other: Home exercise programPatients receiving a home-based exercise program following a neurological condition (stroke, hemiplegia) as part of neurological rehabilitation (subcohort). |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- * Be 18 years of age or older * To have a musculoskeletal disease (degenerative, neurological or orthopedic) * To be given a home exercise program * To have cognitive and language functions to communicate, to be a volunteer
Key inclusion criteria (4 listed)
- Be 18 years of age or older
- To have a musculoskeletal disease (degenerative, neurological or orthopedic)
- To be given a home exercise program
- To have cognitive and language functions to communicate, to be a volunteer
Key exclusion criteria (4 listed)
- Those with major psychiatric illness
- Those with cognitive dysfunction
- Those with communication disorders, reluctant/reluctant to participate
- Those with any condition other than a primary degenerative, orthopedic, or neurological disease that could significantly affect exercise adherence, including musculoskeletal or systemic disorders (e.g., severe anemia, heart failure, respiratory failure, uncontrolled diabetes, inflammatory rheumatic disease, recent fractures, or active infections).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Home exercise programPatients with chronic degenerative musculoskeletal disorders receiving a home exercise program | Other | Degenerative rehabilitation |
| Home exercise programPatients receiving a home exercise program as part of post-operative orthopedic rehabilitation | Other | Neurological |
| Home exercise programPatients receiving a home exercise program following a neurological condition (stroke,hemiplegia) as part of rehabilitation | Other | Orthopedic rehabilitation |
Primary outcome
Exercise Adherence Rating Scale
Time frame: 6th week
It was developed to evaluate compliance with home exercise programs. The first part (Group A) contains the participant's general information about the exercise program; the second part (Group B; 0-24 points) examines the frequency and sustainability of exercise behaviors; the third part (Group C; 0-40 points) evaluates cognitive and environmental factors affecting exercise adherence. The total score ranges from 0-64, with higher scores indicating greater compliance. The Turkish adaptation, including validation and reliability analysis, was conducted in 2019.
5 secondary outcomes
VAS
Time frame: Baseline and 6th week
Beck Depression Index
Time frame: Baseline and 6th week
Barthel Index
Time frame: Baseline ve 6th week
Tampa Kinesiophobia Scale
Time frame: Baseline and 6th week
Health assessment questionnaire
Time frame: Baseline and 6th week
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
ramazan Yılmaz, assoc prof contact
Ramazan Yilmaz study chair
Konya Beyhekim Training and Research Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Exercise Training and Adherence, Treatment, run by Konya Beyhekim Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 25 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Merve Albayrak, Dr (+905556232674, mervealbyrk20@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Exercise Adherence Rating Scale (time frame: 6th week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Mar 2026; AzTrials last refreshed its copy on 26 Oct 2026.