Glycemic Index and Glycemic LoadNCT07015827
Effect of Locally Produced Mango Variety on Glycemic Index
A study testing Mango (langra), mango (chaunsa) and MANGO (SINDHRI) in people with Glycemic Index and Glycemic Load, run by Rehman Medical Institute - RMI.
Trial summary
This randomized trial aims to assess the glycemic index (GI) of locally available mango varieties in healthy adult participants, using glucose as the reference food. The study will evaluate the postprandial blood glucose response elicited by selected mango varieties and compare it to the response produced by a… Read more about this study
- Who is it for?
- Ages 18 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Glycemic Index and Glycemic Load
- What is being tested?
- Mango (langra), mango (chaunsa) and MANGO (SINDHRI)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- No sites listed yet
- Study dates
- Jun 2025to Sep 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy non-diabetic adults
- Normal fasting blood glucose levels
- Willingness to provide informed consent
Who cannot join
- Diagnosis of diabetes mellitus or impaired glucose tolerance
- Gastrointestinal, metabolic, or endocrine disorders
- Current use of medications affecting blood glucose
- Pregnant or lactating women
- Smoking or alcohol consumption
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
This randomized trial aims to assess the glycemic index (GI) of locally available mango varieties in healthy adult participants, using glucose as the reference food. The study will evaluate the postprandial blood glucose response elicited by selected mango varieties and compare it to the response produced by a standard glucose . The objective is to determine whether certain mango varieties have a lower glycemic impact, which may be relevant for dietary planning and public health recommendations.
Read the detailed description
This randomized trial aims to assess the glycemic index (GI) of locally available mango varieties in healthy adult participants, using glucose as the reference food. The study will evaluate the postprandial blood glucose response elicited by selected mango varieties and compare it to the response produced by a standard glucose . The objective is to determine whether certain mango varieties have a lower glycemic impact, which may be relevant for dietary planning and public health recommendations.
- Conditions
- Glycemic Index and Glycemic Load
- Being tested
- Mango (langra), mango (chaunsa), MANGO (SINDHRI)
- Keywords
- Glycemic index, posprandial glucose response, glycemic load
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mango (langra)Other
Participants will consume mango variety A . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast.
mango (chaunsa)Other
Participants will consume mango variety B . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast.
MANGO (SINDHRI)Other
Participants will consume mango variety C . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast.
| Study group | Role | What they receive |
|---|---|---|
| Single group (cross over) | Active comparator | Participants will consume 50 grams of glucose solution. This serves as the reference food for calculating the glycemic index Receives: Other: Mango (langra); Other: mango (chaunsa); Other: MANGO (SINDHRI) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Glycemic Index (GI) of Mango Varieties
Glycemic index will be calculated for each mango variety by measuring the postprandial blood glucose response over 120 minutes and comparing the incremental area under the curve (iAUC) to that of a standard glucose reference.
Measured: 0 to 120 minutes after consumption of test food
Secondary outcomes (1)
Peak Blood Glucose Level
Maximum capillary blood glucose concentration observed after consumption of each test food.
Measured: 0 to 120 minutes after consumption
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2025
- Study startJun 2025 (estimated)
- Primary completionAug 2025 (estimated)
- Study completionSep 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Glycemic Index and Glycemic LoadStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Rehman Medical Institute - RMI
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Naseer Ahmed, Rehman Medical Institute - RMI
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07015827
- Sponsor's protocol ID
- GL/GI-NA_1V1
- Status last verified
- Jun 2025
- First submitted
- 3 Jun 2025
- Last updated
- 11 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 11 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Locally Produced Mango Variety on Glycemic Index
- ClinicalTrials.gov ID
- NCT07015827
- Acronym / sponsor ID
- GL/GI-NA_1V1
- Conditions
- Glycemic Index and Glycemic Load
- Keywords
- Glycemic index, posprandial glucose response, glycemic load
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Rehman Medical Institute - RMIUniversity, hospital or other
- Study start
- Jun 2025 (estimated)
- Primary completion
- Aug 2025 (estimated)
- Study completion
- Sep 2025 (estimated)
- First posted
- 11 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized trial aims to assess the glycemic index (GI) of locally available mango varieties in healthy adult participants, using glucose as the reference food. The study will evaluate the postprandial blood glucose response elicited by selected mango varieties and compare it to the response produced by a standard glucose . The objective is to determine whether certain mango varieties have a lower glycemic impact, which may be relevant for dietary planning and public health recommendations.
Detailed description
This randomized trial aims to assess the glycemic index (GI) of locally available mango varieties in healthy adult participants, using glucose as the reference food. The study will evaluate the postprandial blood glucose response elicited by selected mango varieties and compare it to the response produced by a standard glucose . The objective is to determine whether certain mango varieties have a lower glycemic impact, which may be relevant for dietary planning and public health recommendations.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Single group (cross over) | Active comparator | Other: Mango (langra), Other: mango (chaunsa), Other: MANGO (SINDHRI)Participants will consume 50 grams of glucose solution. This serves as the reference food for calculating the glycemic index |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Healthy non-diabetic adults
- Normal fasting blood glucose levels
- Willingness to provide informed consent
Key exclusion criteria (5 listed)
- Diagnosis of diabetes mellitus or impaired glucose tolerance
- Gastrointestinal, metabolic, or endocrine disorders
- Current use of medications affecting blood glucose
- Pregnant or lactating women
- Smoking or alcohol consumption
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mango (langra)Participants will consume mango variety A . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast. | Other | Single group (cross over) |
| mango (chaunsa)Participants will consume mango variety B . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast. | Other | Single group (cross over) |
| MANGO (SINDHRI)Participants will consume mango variety C . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast. | Other | Single group (cross over) |
Primary outcome
Glycemic Index (GI) of Mango Varieties
Time frame: 0 to 120 minutes after consumption of test food
Glycemic index will be calculated for each mango variety by measuring the postprandial blood glucose response over 120 minutes and comparing the incremental area under the curve (iAUC) to that of a standard glucose reference.
1 secondary outcome
Peak Blood Glucose Level
Time frame: 0 to 120 minutes after consumption
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Jun 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Mango (langra), mango (chaunsa) and MANGO (SINDHRI) in people with Glycemic Index and Glycemic Load, run by Rehman Medical Institute - RMI.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 11 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Naseer Ahmed (03305485960, dr.naseer99@mail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Glycemic Index (GI) of Mango Varieties (time frame: 0 to 120 minutes after consumption of test food). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Jun 2025.