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Prescribing DecisionsNCT06605807

Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions

A study testing Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization. in people with Prescribing Decisions and Diabetes, run by University of Pittsburgh at 1 site in United States.

Active, not recruiting

Under way, not looking for participants. Everyone needed has enrolled. The study is still running.

Official record
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Trial summary

The goal of this pilot clinical trial is to learn if providing a clinical decision framework for managing older adults chronic conditions during hospitalization to inpatient clinicians improves clinicians' ability to individualize chronic condition prescribing decisions for hospitalized older adults (65 and older). Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Prescribing Decisions, Diabetes, Multimorbidity
What is being tested?
Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization.
Could I receive a placebo?
No, everyone receives an active treatment
How many people
64 participants
Where
1 siteUnited States
Study dates
13 Nov 2025to 30 Jan 2027
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Attending clinicians who practice on the general medicine or hospital medicine service at UPMC Presbyterian, UPMC Montefiore, UPMC Shadyside, UPMC Mercy, or UPMC Magee-Women's Hospital campuses.
  • Practicing on the general medicine or hospital medicine service. This population may include physicians with training in general internal medicine, hospital medicine, family practice, internal medicine subspecialities, as well as advance practice clinicians.
  • Adult aged 65 years or older who are hospitalized under the care of a participating clinician and discharged home.
  • Eligible patients must recieve at least one cardiometabolic medication change at hospital discharge (can include new medication starts, stops, or dose changes). Cardiometabolic medications include any class of antihypertensive, lipid lowering, anti-platelet, or glucose lowering medications regardless of indication for use.

Who cannot join

  • Anticipating leaving current clinical position within next 3 months
  • Less than 4 weeks of inpatient attending service scheduled within 3 months of recruitment
  • Patient Participants:
  • Incapacity for informed consent / unable to answer survey questions due to cognitive impairment
  • Enrolled in hospice care

Trial locations and contacts

1 site in 1 country.

United States1 site
  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213

Other trials in United States

About this study

Official title: Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions: Aim 3

The goal of this pilot clinical trial is to learn if providing a clinical decision framework for managing older adults chronic conditions during hospitalization to inpatient clinicians improves clinicians' ability to individualize chronic condition prescribing decisions for hospitalized older adults (65 and older). The main questions it aims to answer are:

  • Will the clinical decision framework lead to clinicians having greater confidence to individualize discharge prescribing?
  • Will clinicians using the framework discharge make fewer changes to hospitalized older adults with home diabetes and hypertension medications than they did prior to receiving the framework?
  • Will older adult patients of participating clinicians will report fewer gaps in understanding of medication changes after the clinician is exposed to the framework?
Read more

Researchers will compare participating clinician survey responses and prescribing records from before and after an educational session presenting the clinical decision framework.

Participants will be asked to

  • Attend a one-time educational session on the clinical decision framework
  • Complete 2 electronic surveys, one before and one following the educational session.
  • Agree for researchers to contact their patients, in order for patients to complete a one-time phone survey about changes made to home medications during hospitalization and quality of communication from the hospital team.
Being tested
Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization.
Keywords
prescribing, hypertension, diabetes, geriatrics, polypharmacy, multimorbidity, hospital medicine
Medical subject headings
Diabetes Mellitus, Hypertension

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization.Other

    All clinicians will attend an educational session where they will be provided a clinical decision framework for management of chronic conditions in hospitalized older adults, reviewing guiding principles for managing chronic disease in the hospital, and working through case-based hypothetical examples.

Study groups in NCT06605807
Study groupRoleWhat they receive
Clinician ParticipantsExperimentalAll clinician participants will undergo the same intervention, an educational session providing a clinical decision framework for managing older adults' chronic conditions during hospitalization.
Receives: Other: Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Clinician - Change in Prescribing Self-Efficacy

    For each clinician participant the investigators will ask their self-efficacy to individualize blood pressure and diabetes treatment decisions for hospitalized older adults. Measured through ten 7-point Likert scale questions measured [Strongly Disagree - Strongly Agree]. Scores will be summed and range from 10 (all Strongly Disagree) to 70 (all Strongly Agree).

    Measured: Baseline and three months post-intervention

Secondary outcomes (12)
  1. Clinician - Change in Attitudes

    The investigators will ask clinicians 8 questions about their attitudes towards individualizing antihypertensive and diabetes treatment decisions on a 7-point Likert scale. Individualizing antihypertensive and diabetes treatment decisions for hospitalized older adults is:

    Necessary - Unnecessary Beneficial - Harmful High-priority - Low-priority Worthless - Useful.

    Scores will be summed and range from 8 to 56.

    Measured: Baseline and three months post-intervention

  2. Clinician - Discharge Prescribing

    For each clinician participant, the investigators will review the electronic health record for all hospitalized patients aged 65 years and older who were discharged alive under the clinician participant's care in the 2 months before and 3 months after the intervention to identify all antihypertensive and diabetes medication changes made during hospitalization. The investigators will compare the proportion of patients discharged with cardiometabolic medication changes in the 2 months prior to the intervention to the 3 months after the intervention. The investigators will examine proportion of patients receiving medication intensifications and the proportion receiving any medication change.

    Measured: Pre-intervention and post-intervention (2 months before and 3 months after the intervention)

  3. Patient - Change in Medication Discrepencies

    The investigators will ask each enrolled patient how they are taking each of their cardiometabolic medications and compare their current reported medication use to the hospital discharge summary. The investigators will compare the proportion of patient participants reported a medication discrepancy (taking medication differently than hospital discharge summary) in the pre-intervention period to the post-intervention period.

    Measured: Single time survey within a week of discharge from clinician participants care.

  4. Clinician - Acceptability of Clinical Decision Framework

    The investigators will ask clinicians if they used the clinical decision framework and 7 questions on a 7 point Likert scale (strongly disagree to strongly agree) regarding the framework's clarity, length, and whether it was useful. The investigators will ask what they liked about the framework and what would they change. The investigators will ask about facilitators and barriers to using the framework and whether they plan to keep using it. Scores will be summed and range from 7 to 49.

    Measured: 3 months post-intervention

  5. Clinician - Change in Intentions

    The investigators will ask each enrolled clinician two questions to assess choice predisposition (leaning) towards individualizing blood pressure and diabetes medications prescribing decisions during hospitalization using two 7-point Likert Scales (Strongly Disagree to Strongly Agree). Scores will be summed and range from 2 (all Strongly Disagree) to 14 (all Strongly Agree).

    Measured: Baseline and three months post-intervention

  6. Clinician - Change in Perceived Norms

    The investigators will ask each enrolled clinician six questions on their perceptions on norms on individualizing blood pressure and diabetes treatment decisions for hospitalized older adults. Measured through 7-point Likert scale questions measured [Strongly Disagree - Strongly Agree]. Scores will be summed and range from 6 (all Strongly Disagree) to 42 (all Strongly Agree).

    Measured: Baseline and three months post-intervention

  7. Clinician - Awareness of Evidence Base

    The investigators will ask each enrolled clinician to respond to four questions regarding their familiarity with the evidence base for the treatment of blood pressure and diabetes while a patient is hospitalized. These will be framed as four 7-point Likert Scales (Strongly Disagree to Strongly Agree). Scores will be summed and range from 4 (all Strongly Disagree) to 28 (all Strongly Agree).

    Measured: Baseline and three months post-intervention

  8. Patient - Change in Overall Hospital Experience

    The investigators will ask each enrolled patient to rate their overall hospital experience from 0 to 10. Where 0 is I had a very poor experience and 10 is I had a very good experience. Scores will be summed from 0 to 10. The investigators will compare average scores of patients in the pre-intervention period to the post-intervention period

    Measured: Baseline and three months post-intervention

  9. Patient - Change in Experience in the Hospital

    The investigators will ask each enrolled patient a 4 question survey on communication during their hospital stay. Possible answers include never (1), sometimes (2), usually (3), and always (4). Scores will be summed from 4 to 16. The investigators will compare mean scores of patients in the pre-intervention period to the post-intervention period.

    Measured: Baseline and three months post-intervention

  10. Patient - Change in Experience Leaving the Hospital

    The investigators will ask each enrolled patient a 3 question survey on communication when they left the hospital. Possible answers include not at all (1), partly (2), quite a bit (3), completely (4), and not applicable (0). Scores will be summed from 0 to 12. The investigators will compare mean scores of patients in the pre-intervention period to the post-intervention period.

    Measured: Baseline and three months post-intervention

  11. Patient - Change in Understanding of Medication Changes

    The investigators will ask each enrolled patient their understanding of the reason for each cardiometabolic medication change made at hospital discharge and compare their understanding to the hospital discharge summary rationale to identify concordant versus discordant understanding. The investigators will compare the proportion of patients with discordant understanding of cardiometabolic medication changes in the pre-intervention period to the post-intervention period.

    Measured: Baseline and three months post-intervention

  12. Patient - Change in Comprehension of Disease Monitoring

    The investigators will ask each patient participant enrolled if the hospital discussed their blood pressure and/or provided guidance on disease monitoring (e.g. blood pressure or blood glucose) after discharge. The investigators will compare the proportion of patients reporting guidance on disease monitoring from the pre-intervention to post-intervention period.

    Measured: Baseline and three months post-intervention

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted20 Sep 2024
  2. Study start13 Nov 2025
  3. Primary completion17 Aug 2026
  4. Study completion30 Jan 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Health services research
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrolment
64 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06605807
Sponsor's protocol ID
STUDY24070027
Other IDs
K76AG074878
Status last verified
Aug 2026
First submitted
13 Sep 2024
Last updated
4 Nov 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization. in people with Prescribing Decisions and Diabetes, run by University of Pittsburgh at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: under way, not looking for participants, as of the sponsor's last update on 4 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Clinician - Change in Prescribing Self-Efficacy (time frame: Baseline and three months post-intervention). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Nov 2026.

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