Research institution
University of Pittsburgh Clinical Trials
Studies where University of Pittsburgh is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 167Nocturia, Insomnia
Addressing Nocturia in Older Women Utilizing Behavioral Sleep Intervention and Brief Mindfulness
The goal of this clinical trial is to examine and compare the effect of behavioral sleep treatment: BBTI (brief behavioral treatment of insomnia) and brief mindfulness (MI), independently and combined vs control on frequency of…
- Trial name
- ANOWSM (NCT07760779)
- Testing
- Brief behavioral treatment of insomnia, MI, Control
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Cutaneous T-cell Lymphoma, Sezary Syndrome
Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research
This is a tissue, urine, and blood banking protocol for cutaneous t-cell lymphoma (CTCL), eczema, and atopic dermatitis patients for current and future research.
- Conditions
- Cutaneous T-cell Lymphoma, Sezary Syndrome, Mycosis Fungoides, Eczema
- Trial name
- NCT00177268
- Testing
- Blood draw, skin biopsy or urine collection
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pittsburgh
People Who Use Opioids/People With Opioid Use Disorder (OUD)
Prescribe to Prevent HIV: A Hybrid Trial Helping Addiction Clinics Prevent HIV & Infections Through Safer Drug Use Support
In the U.S., an estimated 3.6 million people who inject drugs (PWID) face a growing yet preventable health crisis, with rising cases of serious injection-related infections (SIRI), including HIV, due to limited access to two…
- Trial name
- P2PH (NCT07073924)
- Testing
- Implementation strategy bundle
- Where
- 4 sites in United States
- Volunteers
- 536 people
- Sponsor
- University of Pittsburgh
Dementia, Postoperative Delirium (POD)
Prediction and Prevention of Postoperative Mortality and Morbidity
This study will contribute to creating a prospective and automated preoperative risk assessment algorithm for predicting 30-day mortality, major adverse cardiac and cerebrovascular events (MACCE), and postoperative neurocognitive…
- Conditions
- Dementia, Postoperative Delirium (POD), Postoperative Neurocognitive Disorder, Major Adverse Cardiac and Cerebrovascular Events
- Trial name
- NCT06042413
- Testing
- Personalized CPC Prehabilitation, Cognitive Training, Meditation
- Where
- 5 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- University of Pittsburgh
Epilepsy, Speech
Neural Mechanisms for Stopping Ongoing Speech Production (Study 2)
Speech and communication disorders often result in aberrant control of the timing of speech production, such as making improper stops at places where they should not be.
- Trial name
- NCT07713706
- Testing
- Speech Production Tasks
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Pittsburgh
Skin Barrier Dysfunction, Healthy Volunteers
Effect of FPP on Cutaneous Barrier Integrity
This pilot study will test how Fermented Papaya Preparation (FPP) impacts overall TEWL of areas that commonly display diminished barrier function, such as the skin from face, arms, and hands.
- Trial name
- FPP OSATO (NCT07725835)
- Testing
- Fermented Papaya Preparation (FPP)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pediatric Sepsis
Personalized Metabolic Nutrition Sepsis Study
Children with sepsis, a condition in which infection causes organ dysfunction will be enrolled with parental permission in this study.
- Trial name
- PMNS (NCT07910591)
- Testing
- For group Peds Sep A: Standard nutrition will be given, For Group Peds SepB: Low leucine, isoleucine formula, For Group Peds Sep C: Medium chain triglyceride oil enriched formula.
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pittsburgh
Suicide, Bereavement
Risk and Resilience to Suicide Following Late-Life Spousal Bereavement
The purpose of the RISE study is to examine how the 24-hour rhythm of sleep and social activity relate to mood and suicidal ideation among older adults that recently lost a spouse or life partner.
- Trial name
- RISE (NCT06191484)
- Testing
- WELL Behavioral Probe
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- University of Pittsburgh
Acute Respiratory Tract Infection, Ear Infection
Enhanced Telemedicine in Primary Care for Acute Respiratory Tract Infections Study
Young children often receive antibiotics for pediatric acute respiratory tract infections (ARTIs) - common childhood diagnoses like ear infections, strep throat, sinusitis, and colds - but many of these antibiotics are prescribed…
- Conditions
- Acute Respiratory Tract Infection, Ear Infection, Throat Infection, Acute Respiratory Tract Infections
- Trial name
- Tele-PARTI (NCT07845526)
- Testing
- Tele-Otoscope Enabled Primary Care, eBook-supported primary care
- Where
- 2 sites in United States
- Volunteers
- 450 people
- Sponsor
- University of Pittsburgh
Penis/Surgery, Penis/Injuries
Autologous Fat Grafting Beneath Penile Split Thickness Skin Graft Placement During Penile Reconstruction
The goal of this randomized interventional clinical trial is to learn if placement of a thin layer of fatty tissue (fat graft) beneath a split-thickness skin graft on the surface of the penis improved outcomes of surgery in men…
- Conditions
- Penis/Surgery, Penis/Injuries, Penile Skin, Adult-Acquired Buried Penis
- Trial name
- NCT07316491
- Testing
- Autologous fat grafting, Genitourinary Reconstruction with Split-Thickness Skin Grafting
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pittsburgh
Completed, with results posted
All 246Community Mobility of Older Adults, Locomotor Adaptability
Increasing Gait Automaticity in Older Adults by Exploiting Locomotor Adaptation
The investigators will test the following: 1) the extent of locomotor adaptation improvement; 2) the association between initial walking automaticity (i.e.
- Conditions
- Community Mobility of Older Adults, Locomotor Adaptability, Gait Automaticity
- Trial name
- NCT04934956
- Testing
- Split-belt walking, Multiple transitions between split-belt and tied-belt walking
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sepsis, Pneumonia
Comparative Effectiveness of Readmission Reduction Interventions for Individuals With Sepsis or Pneumonia
An adaptive platform trial to compare effectiveness of different care models to prevent readmissions for patients hospitalized with sepsis or lower respiratory tract infection.
- Conditions
- Sepsis, Pneumonia, Lower Resp Tract Infection, Covid19
- Trial name
- ACCOMPLISH (NCT04829188)
- Testing
- Structured Telephone Support (STS), Low-intensity Remote Patient Monitoring (RPM-Low), High-intensity Remote Patient Monitoring (RPM-High)
- Where
- United States
- Volunteers
- 1,296 people
- Sponsor
- University of Pittsburgh
Mental Health Issue, Teamwork
Team-Focused Implementation in Child Advocacy Centers
Child Advocacy Centers (CACs) are well-positioned to identify children at risk for mental health problems and to facilitate access to evidence-based treatments.
- Trial name
- NCT05679154
- Testing
- Team-focused Implementation, Standard Implementation
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- University of Pittsburgh
Urgency Urinary Incontinence
Investigation of Brain Mechanisms Involved in the Urinary Continence Mechanism Associated With Aging
Urge urinary incontinence (UUI) is a common problem in older people which vastly reduces quality of life, yet the cause and mechanism of disease are not well understood.
- Trial name
- NCT04599088
- Testing
- Brain functional MRI with simplified urodynamics
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Suicidal Ideation, Suicide, Attempted
Reducing Suicide Ideation Among Young People
It is Cluster Randomized Control Trial research to examine feasibility and relevance of the modified tool Nae Disha for Life, which will incorporate suicide prevention and resilience to reduce suicide ideation among young people…
- Trial name
- NCT06474312
- Testing
- Nae Disha
- Where
- India
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh