E-cigarette UseNCT05906082
Vape-Free Text-Messaging: Pilot Study
A study testing E-cigarette cessation text-messaging intervention in people with E-cigarette Use, run by Jovan Gwon, PhD, RN, FIAAN at 1 site in United States.
Trial summary
This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messaging intervention with young adults in rural areas. Read more about this study
- Who is it for?
- Ages 18 to 24 yearsHealthy volunteers can take part
- Conditions the study is for
- E-cigarette Use
- What is being tested?
- E-cigarette cessation text-messaging intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteUnited States
- Study dates
- 25 May 2023to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 24 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- English speaking
- 18-24 years
- everyday e-cigarette use in the past month
- ownership of a mobile phone or smartphone with texting and internet access abilities
- knowledge of how to use text messages
- plan on quitting e-cigarette use within one month
- home address in a rural county of Wisconsin, Minnesota, North Dakota, and South Dakota
Who cannot join
- Individuals who reported use of other tobacco products (e.g., cigarettes, smokeless tobacco) than e-cigarettes in the past month
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of Wisconsin-Milwaukee
Milwaukee, Wisconsin, 53211
Seok Hyun Gwon, PhD, RN, 4142296462, gwon@uwm.edu
About this study
Official title: Text-messaging E-cigarette Cessation Intervention for Young Adults in Rural Areas: A Pilot Study
This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messaging intervention with young adults in rural areas.
- Conditions
- E-cigarette Use
- Being tested
- E-cigarette cessation text-messaging intervention, Standard care control using standard national resources
- Medical subject headings
- Vaping
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
E-cigarette cessation text-messaging interventionBehavioural
This is the intervention for e-cigarette cessation using text messages targeting young adults in rural areas.
Standard care control using standard national resourcesBehavioural
This is the standard care with national resources from smokefree.gov.
| Study group | Role | What they receive |
|---|---|---|
| Intervention (E-cigarette cessation text-messaging intervention) | Experimental | Not described Receives: Behavioral: E-cigarette cessation text-messaging intervention |
| Standard care (Standard care control using standard national resources) | Active comparator | This standard care group will receive standard care resources from smokefree.gov. Receives: Behavioral: Standard care control using standard national resources |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of participants recruited and randomized
Number of participants recruited and randomized
Measured: Throughout 12 months
Self-reported proportion of text messages read
Proportion of text messages read during the intervention or standard care at 1 month
Measured: At 1 month
Retention rates (proportion of participants remained until 1 month post-intervention from enrollment)
Proportion of participants from enrollment to 1 month post-intervention or standard-care
Measured: At 1 month
Level of acceptability of the intervention
- When you had received our text messages from our VapeFreeTXT program 1 month ago, how many of our text messages did you read on a typical day? Not at all (1) Read about 25% messages (2) Read about half messages (3) Read about 75% messages (4) Read the entire messages (5)
- How useful was our VapeFreeTXT program in helping you quit vaping? Not at all useful (1) Slightly useful (2) Moderately useful (3) Very useful (4) Extremely useful (5)
- Did our VapeFreeTXT program make you think about quitting vaping? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5)
- Do you think our VapeFreeTXT program will change your vaping? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5)
- Would you recommend this program to a friend or others? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5)
Measured: At 1 month
Proportion of salivary cotinine samples returned
Proportion of salivary cotinine samples returned to the office lab for cotinine analysis
Measured: At 1 month
Self-reported 7-days point prevalence abstinence from ENDS and other tobacco
Self-reported 7-days point prevalence abstinence from ENDS and other tobacco
Measured: At 1 month
Concentration of cotinine in saliva
Biochemically verified abstinence evaluated by salivary cotinine samples
Measured: At 1 month
Nicotine dependence (Penn State Electronic Cigarette Dependence Index)
Nicotine dependence (minimum 0 to maximum 20, higher scores mean a worse outcome.)
Measured: At 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jun 2023
- Study start25 May 2023
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for E-cigarette UseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Jovan Gwon, PhD, RN, FIAAN
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Jovan Gwon, PhD, RN, FIAAN, University of Wisconsin, Milwaukee
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05906082
- Sponsor's protocol ID
- 23.179
- Status last verified
- Aug 2025
- First submitted
- 26 May 2023
- Last updated
- 7 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Text-messaging E-cigarette Cessation Intervention for Young Adults in Rural Areas: A Pilot Study
- ClinicalTrials.gov ID
- NCT05906082
- Acronym / sponsor ID
- 23.179
- Conditions
- E-cigarette Use
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Jovan Gwon, PhD, RN, FIAANUniversity, hospital or other
- Study start
- 25 May 2023 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 15 Jun 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messaging intervention with young adults in rural areas.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Intervention (E-cigarette cessation text-messaging intervention) | Experimental | Behavioral: E-cigarette cessation text-messaging intervention |
| Standard care (Standard care control using standard national resources) | Active comparator | Behavioral: Standard care control using standard national resourcesThis standard care group will receive standard care resources from smokefree.gov. |
Who may qualify
- Ages
- 18 to 24 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- English speaking
- 18-24 years
- everyday e-cigarette use in the past month
- ownership of a mobile phone or smartphone with texting and internet access abilities
- knowledge of how to use text messages
Key exclusion criteria (1 listed)
- Individuals who reported use of other tobacco products (e.g., cigarettes, smokeless tobacco) than e-cigarettes in the past month
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| E-cigarette cessation text-messaging interventionThis is the intervention for e-cigarette cessation using text messages targeting young adults in rural areas. | Behavioural | Intervention (E-cigarette cessation text-messaging intervention) |
| Standard care control using standard national resourcesThis is the standard care with national resources from smokefree.gov. | Behavioural | Standard care (Standard care control using standard national resources) |
Primary outcome
Number of participants recruited and randomized
Time frame: Throughout 12 months
Number of participants recruited and randomized
Self-reported proportion of text messages read
Time frame: At 1 month
Proportion of text messages read during the intervention or standard care at 1 month
Retention rates (proportion of participants remained until 1 month post-intervention from enrollment)
Time frame: At 1 month
Proportion of participants from enrollment to 1 month post-intervention or standard-care
Level of acceptability of the intervention
Time frame: At 1 month
1. When you had received our text messages from our VapeFreeTXT program 1 month ago, how many of our text messages did you read on a typical day? Not at all (1) Read about 25% messages (2) Read about half messages (3) Read about 75% messages (4) Read the entire messages (5) 2. How useful was our VapeFreeTXT program in helping you quit vaping? Not at all useful (1) Slightly useful (2) Moderately useful (3) Very useful (4) Extremely useful (5) 3. Did our VapeFreeTXT program make you think about quitting vaping? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5) 4. Do you think our VapeFreeTXT program will change your vaping? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5) 5. Would you recommend this program to a friend or others? Not at all (1) Probably not (2) Neither yes nor no (3) Probably yes (4) Definitely yes (5)
Proportion of salivary cotinine samples returned
Time frame: At 1 month
Proportion of salivary cotinine samples returned to the office lab for cotinine analysis
Self-reported 7-days point prevalence abstinence from ENDS and other tobacco
Time frame: At 1 month
Self-reported 7-days point prevalence abstinence from ENDS and other tobacco
Concentration of cotinine in saliva
Time frame: At 1 month
Biochemically verified abstinence evaluated by salivary cotinine samples
Nicotine dependence (Penn State Electronic Cigarette Dependence Index)
Time frame: At 1 month
Nicotine dependence (minimum 0 to maximum 20, higher scores mean a worse outcome.)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Aug 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing E-cigarette cessation text-messaging intervention in people with E-cigarette Use, run by Jovan Gwon, PhD, RN, FIAAN at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of participants recruited and randomized (time frame: Throughout 12 months). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Aug 2025.