Tobacco ProductsNCT07599462
Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes
A study testing communication in people with Tobacco Products and Cigarettes, run by UNC Lineberger Comprehensive Cancer Center at 1 site in United States.
Trial summary
The study is a pilot test of effectiveness of communication campaign ads on interest in quitting combustible cigarettes and e-cigarettes. Over the course of 5 weeks, participants are sent ads that are designed to encourage quitting and then answer surveys. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Tobacco Products, Cigarettes, Electronic Cigarettes
- What is being tested?
- communication
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 99 participants
- Where
- 1 siteUnited States
- Study dates
- 26 May 2026to 7 Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- use cigarettes every day or some days
- use e-cigarettes every day or some days
- age 18 or older
- ability to read and answer questions in English
Who cannot join
- under age 18
Trial locations and contacts
1 site in 1 country.
United States1 site
Recruitment is online and national, using existing Qualtrics survey panels
Chapel Hill, North Carolina, 27599
About this study
Official title: Designing and Evaluating Communication for Dual Users of E-cigarettes and Combustible Cigarettes
The study is a pilot test of effectiveness of communication campaign ads on interest in quitting combustible cigarettes and e-cigarettes. Over the course of 5 weeks, participants are sent ads that are designed to encourage quitting and then answer surveys.
Read the detailed description
Qualtrics Services will enroll 90 US adult dual users to participate in this study using existing panels. Inclusion criteria are current cigarette and e-cigarette use, age 18 or older, and ability read and answer questions in English, and willingness to receive text messages. Qualtrics will contact, screen, consent and randomize participants into 1 of 2 study arms: exposure to a 3 cycles of 6 ads encouraging them to quit smoking and vaping simultaneously or 6 ads encouraging them to quit sequentially (quitting smoking first followed by quitting vaping). The ads (one per day) are presented along with brief daily surveys. The primary outcome in intent to quit smoking.
- Conditions
- Tobacco Products, Cigarettes, Electronic Cigarettes
- Being tested
- communication
- Keywords
- dual use, tobacco cesation, communication campaign
- Medical subject headings
- Vaping
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
communicationOther
Also called advertising
Participants view an image that is an ad designed to encourage them to quit their use of cigarettes and e-cigarettes.
| Study group | Role | What they receive |
|---|---|---|
| Simultaneous quit messages | Experimental | Participants in this arm receive messages encouraging them to quit both cigarettes and e-cigarettes at the same time. Receives: Other: communication |
| Sequential quit messages | Experimental | Participants in this arm receive messages encouraging them to quit cigarettes first, followed by e-cigarettes. Receives: Other: communication |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cigarette quit intention
A three question scale of interest in quitting cigarettes: How [interested are you in quitting / likely are you to quit / much do you intend to quit] smoking cigarettes in the next 6 months? 4 point response scale.
Measured: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Secondary outcomes (5)
E-cigarette quit intention
A three question scale of interest in quitting vaping (e-cigarettes): How [interested are you in quitting / likely are you to quit / much do you intend to quit] vaping in the next 6 months? 4 point response scale.
Measured: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Cigarette quit attempts
A question: In the last 7 days, have you attempted to stop smoking cigarettes? (yes/no)
Measured: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
E-cigarette quit attempts
A question: In the last 7 days, have you attempted to stop vaping? (yes/no)
Measured: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Forgoing cigarettes
A question: In the last 7 days, how many times did you stop yourself from having a cigarette because you wanted to smoke less? [numerical response 0-250]
Measured: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Forgoing e-cigarettes
A question: In the last 7 days, how many times did you stop yourself from vaping because you wanted to smoke less? [numerical response 0-250]
Measured: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 May 2026
- Study start26 May 2026
- Primary completion7 Jul 2026
- Study completion7 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tobacco ProductsStudies of the same condition, open and under way.
- More trials run by UNC Lineberger Comprehensive Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 99 participants (actual)
Sponsor and investigators
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07599462
- Sponsor's protocol ID
- 25-2560
- Other IDs
- K01CA253234
- Status last verified
- Oct 2026
- First submitted
- 14 May 2026
- Last updated
- 28 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: With the small sample size, we would want to ensure participants are not identifiable.
Study at a glance
From the registry record, last updated by the sponsor on 28 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Designing and Evaluating Communication for Dual Users of E-cigarettes and Combustible Cigarettes
- ClinicalTrials.gov ID
- NCT07599462
- Acronym / sponsor ID
- 25-2560
- Conditions
- Tobacco Products, Cigarettes, Electronic Cigarettes
- Keywords
- dual use, tobacco cesation, communication campaign
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 99 participants (actual)
- Lead sponsor
- UNC Lineberger Comprehensive Cancer CenterUniversity, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Study start
- 26 May 2026 (actual)
- Primary completion
- 7 Jul 2026 (actual)
- Study completion
- 7 Jul 2026 (actual)
- First posted
- 20 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study is a pilot test of effectiveness of communication campaign ads on interest in quitting combustible cigarettes and e-cigarettes. Over the course of 5 weeks, participants are sent ads that are designed to encourage quitting and then answer surveys.
Detailed description
Qualtrics Services will enroll 90 US adult dual users to participate in this study using existing panels. Inclusion criteria are current cigarette and e-cigarette use, age 18 or older, and ability read and answer questions in English, and willingness to receive text messages. Qualtrics will contact, screen, consent and randomize participants into 1 of 2 study arms: exposure to a 3 cycles of 6 ads encouraging them to quit smoking and vaping simultaneously or 6 ads encouraging them to quit sequentially (quitting smoking first followed by quitting vaping). The ads (one per day) are presented along with brief daily surveys. The primary outcome in intent to quit smoking.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Simultaneous quit messages | Experimental | Other: communicationParticipants in this arm receive messages encouraging them to quit both cigarettes and e-cigarettes at the same time. |
| Sequential quit messages | Experimental | Other: communicationParticipants in this arm receive messages encouraging them to quit cigarettes first, followed by e-cigarettes. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- use cigarettes every day or some days
- use e-cigarettes every day or some days
- age 18 or older
- ability to read and answer questions in English
Key exclusion criteria (1 listed)
- under age 18
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| communicationAlso: advertisingParticipants view an image that is an ad designed to encourage them to quit their use of cigarettes and e-cigarettes. | Other | Sequential quit messages, Simultaneous quit messages |
Primary outcome
Cigarette quit intention
Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
A three question scale of interest in quitting cigarettes: How [interested are you in quitting / likely are you to quit / much do you intend to quit] smoking cigarettes in the next 6 months? 4 point response scale.
5 secondary outcomes
E-cigarette quit intention
Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Cigarette quit attempts
Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
E-cigarette quit attempts
Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Forgoing cigarettes
Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Forgoing e-cigarettes
Time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Oct 2026.
- University of North Carolina Lineberger Comprehensive Cancer Center Clinical TrialsLink provided by the sponsor.
- Individual participant dataSharing planned: Undecided. With the small sample size, we would want to ensure participants are not identifiable.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing communication in people with Tobacco Products and Cigarettes, run by UNC Lineberger Comprehensive Cancer Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cigarette quit intention (time frame: Measured at baseline (Day 0) weekly surveys (Days 7, 14), post 1 survey (Day 21), and post 2 survey (Day 35)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Oct 2026.