Canine RetractionNCT04020952
Effect of Archwire Gauge on the Rate of Canine Retraction
A study testing st.st 0.019×0.025" wire, st.st 0.016×0.022" wire and st.st 0.017×0.025" wire in people with Canine Retraction, run by Cairo University at 1 site in Egypt.
Trial summary
trial will be done to evaluate the effect of archwire gauge on the rate of canine retraction, canine tip and torque, root resorption and loss of anchorage in maxillary dental protrusion cases requiring first premolars extraction. Read more about this study
- Who is it for?
- Ages 16 to 26 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Canine Retraction
- What is being tested?
- st.st 0.019×0.025" wire, st.st 0.016×0.022" wire and st.st 0.017×0.025" wire
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 18 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Sep 2019to 15 Jul 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 to 26 years
- Women only
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Adult females (age range 18-28 years old).
- Maxillary dental protrusion indicating first premolars extraction.
- Full permanent dentition (not necessitating third molars).
Who cannot join
- Patients having systemic diseases or on medications that would affect tooth movement.
- Active periodontal disease or obvious bone resorption in maxillary arch.
- Patients with habits that are detrimental to dental occlusion (thumb sucking, tongue thrusting … etc.).
- Previous orthodontic treatment.
- Missing teeth.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Archwire Gauge on the Rate of Canine Retraction in Adults: A Randomized Clinical Trial
trial will be done to evaluate the effect of archwire gauge on the rate of canine retraction, canine tip and torque, root resorption and loss of anchorage in maxillary dental protrusion cases requiring first premolars extraction.
Read the detailed description
Three working archwires of different gauges will be used during canine retraction; st.st 0.019×0.025" as a comparator, st.st 0.016×0.022" and st.st 0.017×0.025" wires as interventions. after levelling and alignment till reaching the working archwire, it will be left in place for a month then maxillary first premolars will be extracted and base line records will be taken(digital models, digital periapical radiographs and panorama). digital models will be taken monthly to measure rate of canine retraction for 6 months. after 6 month evaluation of anchorage loss, change in canine tip and torque will be done on last obtained digital model , panorama will be taken to evaluate the change in canine tip and digital periapical radiograph will be taken and compared with the preretraction radiograph to evaluate amount of root resorption.
- Conditions
- Canine Retraction
- Being tested
- st.st 0.019×0.025" wire, st.st 0.016×0.022" wire, st.st 0.017×0.025" wire
- Keywords
- canine retraction, archwire gauge
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
st.st 0.019×0.025" wireOther
rectangular stainless steel wire that will be used during canine retraction after first premolars extraction
st.st 0.016×0.022" wireOther
rectangular stainless steel wire that will be used during canine retraction after first premolars extraction
st.st 0.017×0.025" wireOther
rectangular stainless steel wire that will be used during canine retraction after first premolars extraction
| Study group | Role | What they receive |
|---|---|---|
| st.st 0.019×0.025" wire | Active comparator | Not described Receives: Other: st.st 0.019×0.025" wire |
| st.st 0.016×0.022" wire | Experimental | Not described Receives: Other: st.st 0.016×0.022" wire |
| st.st 0.017×0.025" wire | Experimental | Not described Receives: Other: st.st 0.017×0.025" wire |
What is being measured
The primary outcome is the main question the study is designed to answer.
rate of canine retraction
the distance that canine moved every month
Measured: 6 months
Secondary outcomes (4)
change in canine tip
change in canine crown tipping to certain reference plane with the aid of cone beam computed tomography
Measured: 6 months
change in canine torque
change in canine crown and root torque to certain reference plane with the aid of cone beam computed tomography
Measured: 6 months
loss of molar anchorage
assess from digital models if there is change in mesio-distal position of maxillary first molar
Measured: 6 months
amount of canine root resorption
assess amount of root resorption (if occurred) with the aid of cone beam computed tomography
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jul 2019
- Study start10 Sep 2019
- Primary completion20 Sep 2020
- Study completion15 Jul 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Canine RetractionStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Three groups of patients each receives different wire gauge during canine retraction phase during space closure.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 18 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Aml Saeed Mohamed Abdel qader, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04020952
- Sponsor's protocol ID
- 334
- Status last verified
- Jul 2022
- First submitted
- 9 Jul 2019
- Last updated
- 22 Jul 2022
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Abdelkader ASM, Abd El-Ghafour M, Dehis HM, El Sharaby FA, Labib AH. Effect of archwire size on the rate of canine retraction in adult women : A randomized clinical trial. J Orofac Orthop. 2026 Aug;87(Suppl 1):1-11. doi: 10.1007/s00056-025-00577-y. Epub 2025 Mar 25.
PubMed 40131446
Study at a glance
From the registry record, last updated by the sponsor on 22 Jul 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Archwire Gauge on the Rate of Canine Retraction in Adults: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT04020952
- Acronym / sponsor ID
- 334
- Conditions
- Canine Retraction
- Keywords
- canine retraction, archwire gauge
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 18 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 10 Sep 2019 (actual)
- Primary completion
- 20 Sep 2020 (actual)
- Study completion
- 15 Jul 2021 (actual)
- First posted
- 16 Jul 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
trial will be done to evaluate the effect of archwire gauge on the rate of canine retraction, canine tip and torque, root resorption and loss of anchorage in maxillary dental protrusion cases requiring first premolars extraction.
Detailed description
Three working archwires of different gauges will be used during canine retraction; st.st 0.019×0.025" as a comparator, st.st 0.016×0.022" and st.st 0.017×0.025" wires as interventions. after levelling and alignment till reaching the working archwire, it will be left in place for a month then maxillary first premolars will be extracted and base line records will be taken(digital models, digital periapical radiographs and panorama). digital models will be taken monthly to measure rate of canine retraction for 6 months. after 6 month evaluation of anchorage loss, change in canine tip and torque will be done on last obtained digital model , panorama will be taken to evaluate the change in canine tip and digital periapical radiograph will be taken and compared with the preretraction radiograph to evaluate amount of root resorption.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
- Model description
- Three groups of patients each receives different wire gauge during canine retraction phase during space closure.
| Arm | Type | Receives |
|---|---|---|
| st.st 0.019×0.025" wire | Active comparator | Other: st.st 0.019×0.025" wire |
| st.st 0.016×0.022" wire | Experimental | Other: st.st 0.016×0.022" wire |
| st.st 0.017×0.025" wire | Experimental | Other: st.st 0.017×0.025" wire |
Who may qualify
- Ages
- 16 to 26 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- Adult females (age range 18-28 years old).
- Maxillary dental protrusion indicating first premolars extraction.
- Full permanent dentition (not necessitating third molars).
Key exclusion criteria (5 listed)
- Patients having systemic diseases or on medications that would affect tooth movement.
- Active periodontal disease or obvious bone resorption in maxillary arch.
- Patients with habits that are detrimental to dental occlusion (thumb sucking, tongue thrusting … etc.).
- Previous orthodontic treatment.
- Missing teeth.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| st.st 0.019×0.025" wirerectangular stainless steel wire that will be used during canine retraction after first premolars extraction | Other | st.st 0.019×0.025" wire |
| st.st 0.016×0.022" wirerectangular stainless steel wire that will be used during canine retraction after first premolars extraction | Other | st.st 0.016×0.022" wire |
| st.st 0.017×0.025" wirerectangular stainless steel wire that will be used during canine retraction after first premolars extraction | Other | st.st 0.017×0.025" wire |
Primary outcome
rate of canine retraction
Time frame: 6 months
the distance that canine moved every month
4 secondary outcomes
change in canine tip
Time frame: 6 months
change in canine torque
Time frame: 6 months
loss of molar anchorage
Time frame: 6 months
amount of canine root resorption
Time frame: 6 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jul 2022.
- Derived from this study: PubMed 40131446Abdelkader ASM, Abd El-Ghafour M, Dehis HM, El Sharaby FA, Labib AH. Effect of archwire size on the rate of canine retraction in adult women : A randomized clinical trial. J Orofac Orthop. 2026 Aug;87(Suppl 1):1-11. doi: 10.1007/s00056-025-00577-y. Epub 2025 Mar 25.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing st.st 0.019×0.025" wire, st.st 0.016×0.022" wire and st.st 0.017×0.025" wire in people with Canine Retraction, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jul 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
rate of canine retraction (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04020952, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jul 2022.