DyslexiaNCT03364010
Dyslexia, Motor Control and Proprioception
A study testing Evaluation of proprioception, Evaluation of motor learning and Evaluation of written language in people with Dyslexia, run by Institut National de la Santé Et de la Recherche Médicale, France at 1 site in France.
Trial summary
The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings. The investigators compare a group of French students with and without dyslexia aged 10-12. Read more about this study
- Who is it for?
- Ages 10 to 12 yearsHealthy volunteers can take part
- Conditions the study is for
- Dyslexia
- What is being tested?
- Evaluation of proprioception, Evaluation of motor learning and Evaluation of written language
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 56 participants
- Where
- 1 siteFrance
- Study dates
- 4 Jan 2018to 2 Jun 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 12 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- Child with a French social security
- School child
- Native French speaker
- right-handed
- Normal or corrected vision
- Without neurological or psychiatric histories
Show all 16Show fewer
- Agree to participate in the study in agreement with parental rights representatives
- For the dyslexic group :
- pluridisciplinary diagnostic
- never consulted for proprioception before
- without any other leaning disorders like dysphasia
- attention deficit hyperactivity disorder (ADHD) or developmental coordination disorder (DCD)
- For the control group :
- regular school attendance
- never consulted for learning disabilities
- No learning disorders known for their parents or siblings.
Who cannot join
- genetic disorder
- neurological or psychiatric history
- Delayed psychomotor development
- Reeducation or current treatment interfering with the evaluation
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Relationships Between Proprioception, Motor Control and Reading in Children With Dyslexia
The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings. The investigators compare a group of French students with and without dyslexia aged 10-12.
Read the detailed description
2 groups of children (dyslexics and control) will be evaluated on 2 tasks:
- Evaluation of the proprioception: Perception of the speed and Perception of the position
- Evaluation of the motor learning: Estimation of state in the framework of a motor perturbation
- Conditions
- Dyslexia
- Being tested
- Evaluation of proprioception, Evaluation of motor learning, Evaluation of written language
- Keywords
- Motor control, Proprioception
- Medical subject headings
- Dyslexia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Evaluation of proprioceptionBehavioural
Velocity perception and Position perception
Evaluation of motor learningBehavioural
Motor accurancy and State Estimation with visual perturbations
Evaluation of written languageBehavioural
Text reading, Identifying words and Phonological awareness: phonemic blending and phonemic elision
| Study group | Role | What they receive |
|---|---|---|
| Dyslexic and non dyslexic Children | Experimental | Children aged 10-12 Evaluation of proprioception Evaluation of motor learning Evaluation of written language Receives: Behavioral: Evaluation of proprioception; Behavioral: Evaluation of motor learning; Behavioral: Evaluation of written language |
What is being measured
The primary outcome is the main question the study is designed to answer.
Evaluation of proprioception through velocity perception
The ability to perceive motion at 3 different velocities for 3 different joints is assessed using a motorized ergometer. A passive movement is performed by the ergometer and children are tasked to press a button as soon as they feel the movement. We calculate the angle of detection for each speed and compare it between Dyslexic and healthy children.
Measured: 1day
Secondary outcomes (5)
Evaluation of proprioception through position perception
The ability to perceive position is assessed using an ergometer that produces passive movements of 3 different amplitudes on the dominant arm. In a second time, the ergometer produces a passive movement of the same arm and children are tasked to press a button as soon as they feel they are in the exact previously-experienced position. We calculate the angular error and compare it between Dyslexic and healthy children.
Measured: 1 day
Motor learning
The ability to learn new motor tasks is assessed using virtual reality and motor acquisition systems. First we evaluate the motor accuracy and the state estimation by pointing tests. Then visual perturbations are introduced during pointing. Finally, we evaluate motor accuracy and state estimation again.
Measured: 1 day
Text reading
The ability to read aloud a text is assessed using the French standardized test " Alouette ", which provide accuracy in reading aloud age-normed texts (ratio between words that have been correctly read and all the words that have been read).
Measured: 1day
Phonological awareness: phonemic blending and phonemic elision
The ability to derive a phonemic pattern from distinct phonemic units or to substitute a phonemic pattern for another is assessed using the French standardized test " Nepsy2, phonological process " which provide standard deviation in reading aloud by the investigator.
Measured: 1day
Identifying words
The ability to identify words is assessed using the French standardized test " Timé3 ", which provide lexical level and delay reading in silent reading age-normed words.
Measured: 1day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Dec 2017
- Study start4 Jan 2018
- Primary completion9 May 2019
- Study completion2 Jun 2021
Why it stopped: Suspension due to COVID-19
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for DyslexiaStudies of the same condition, open and under way.
- More trials run by Institut National de la Santé Et de la Recherche Médicale, FranceThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 56 participants (actual)
Sponsor and investigators
- Sponsor type
- Other government
- Responsible party
- Sponsor
- Investigators
- Patrick QUERCIA, dr, Principal investigator, Unité Inserm d'affiliation : Laboratoire U1093 Cognition, Action et Plasticité Sensorimotrice
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03364010
- Sponsor's protocol ID
- C17-14
- Other IDs
- 2017-A01547-46
- Status last verified
- Feb 2023
- First submitted
- 27 Sep 2017
- Last updated
- 14 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Laprevotte J, Papaxanthis C, Saltarelli S, Quercia P, Gaveau J. Movement detection thresholds reveal proprioceptive impairments in developmental dyslexia. Sci Rep. 2021 Jan 11;11(1):299. doi: 10.1038/s41598-020-79612-4.
PubMed 33431949
Study at a glance
From the registry record, last updated by the sponsor on 14 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationships Between Proprioception, Motor Control and Reading in Children With Dyslexia
- ClinicalTrials.gov ID
- NCT03364010
- Acronym / sponsor ID
- C17-14
- Conditions
- Dyslexia
- Keywords
- Motor control, Proprioception
- Study type
- Interventional
- Recruitment status
- TerminatedReason stopped: Suspension due to COVID-19
- Enrolment
- 56 participants (actual)
- Lead sponsor
- Institut National de la Santé Et de la Recherche Médicale, FranceOther government
- Study start
- 4 Jan 2018 (actual)
- Primary completion
- 9 May 2019 (actual)
- Study completion
- 2 Jun 2021 (actual)
- First posted
- 6 Dec 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings. The investigators compare a group of French students with and without dyslexia aged 10-12.
Detailed description
2 groups of children (dyslexics and control) will be evaluated on 2 tasks:
- Evaluation of the proprioception: Perception of the speed and Perception of the position
- Evaluation of the motor learning: Estimation of state in the framework of a motor perturbation
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Dyslexic and non dyslexic Children | Experimental | Behavioral: Evaluation of proprioception, Behavioral: Evaluation of motor learning, Behavioral: Evaluation of written languageChildren aged 10-12 Evaluation of proprioception Evaluation of motor learning Evaluation of written language |
Who may qualify
- Ages
- 10 to 12 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (16 listed)
- Child with a French social security
- School child
- Native French speaker
- right-handed
- Normal or corrected vision
Key exclusion criteria (4 listed)
- genetic disorder
- neurological or psychiatric history
- Delayed psychomotor development
- Reeducation or current treatment interfering with the evaluation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Evaluation of proprioceptionVelocity perception and Position perception | Behavioural | Dyslexic and non dyslexic Children |
| Evaluation of motor learningMotor accurancy and State Estimation with visual perturbations | Behavioural | Dyslexic and non dyslexic Children |
| Evaluation of written languageText reading, Identifying words and Phonological awareness: phonemic blending and phonemic elision | Behavioural | Dyslexic and non dyslexic Children |
Primary outcome
Evaluation of proprioception through velocity perception
Time frame: 1day
The ability to perceive motion at 3 different velocities for 3 different joints is assessed using a motorized ergometer. A passive movement is performed by the ergometer and children are tasked to press a button as soon as they feel the movement. We calculate the angle of detection for each speed and compare it between Dyslexic and healthy children.
5 secondary outcomes
Evaluation of proprioception through position perception
Time frame: 1 day
Motor learning
Time frame: 1 day
Text reading
Time frame: 1day
Phonological awareness: phonemic blending and phonemic elision
Time frame: 1day
Identifying words
Time frame: 1day
Results and safety
The study was stopped early (reason given: Suspension due to COVID-19). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 May 2026.
- Results publication: PubMed 33431949Laprevotte J, Papaxanthis C, Saltarelli S, Quercia P, Gaveau J. Movement detection thresholds reveal proprioceptive impairments in developmental dyslexia. Sci Rep. 2021 Jan 11;11(1):299. doi: 10.1038/s41598-020-79612-4.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Patrick QUERCIA, dr principal investigator
Unité Inserm d'affiliation : Laboratoire U1093 Cognition, Action et Plasticité Sensorimotrice
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Evaluation of proprioception, Evaluation of motor learning and Evaluation of written language in people with Dyslexia, run by Institut National de la Santé Et de la Recherche Médicale, France at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 16 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 14 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: Suspension due to COVID-19). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evaluation of proprioception through velocity perception (time frame: 1day). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03364010, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 May 2026.