Clinical trials: Dyslexia
Neurofibromatosis Type 1, Reading Disabilities
Neurobiology and Treatment of Reading Disability in NF-1
The goal of this trial is to determine if children with neurofibromatosis type 1 who have reading disabilities respond the same way-both behaviorally and neurobiologically-to specialized treatment programs as children with…
- Trial name
- NCT00624234
- Testing
- Tutoring Program I, Tutoring Program II
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Developmental Dyslexia
Brain Stimulation With Combined Reading and Motor Training for Children With Dyslexia
This study examines whether combining non-invasive brain stimulation (tDCS) with an integrated reading-and-motor training program improves reading and phonological processing in 9-year-old boys with developmental dyslexia.
- Trial name
- NCT07781761
- Testing
- Active transcranial direct current stimulation (tDCS), Phonological awareness training, Non-targeted fine motor training
- Where
- Iran
- Volunteers
- 160 people
- Sponsor
- Shahid Beheshti University
Dyslexia
Role of Auditory Cortical Oscillations in Speech Processing and Dyslexia
This study aims at investigating the role of low-gamma activity in phonemic encoding and its implication in dyslexia. Indeed, a phonological deficit, i.e.
- Trial name
- NCT04277351
- Testing
- Transcranial alternating current stimulation
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Dyslexia
The Effectiveness of Neuropsychological Rehabilitation in Young Dyslexic Adults
The purpose of this study is to determine whether individual and/ group based neuropsychological rehabilitation focused on psychoeducation and teaching compensatory strategies has positive effects on the psychosocial wellbeing…
- Trial name
- NCT01930500
- Testing
- Individual neuropsychological rehabilitation, Group based neuropsychological rehabilitation
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Rehabilitation Foundation, Finland
Developmental Dyslexia
Restoring Neural Oscillatory Communication in Developmental Dyslexia
Developmental dyslexia (DD) is a multifactorial disorder that hampers the education of about 10% of individuals across cultures and is associated to both phonological and visual deficits.
- Trial name
- NCT05583136
- Testing
- Parietal tACS combined with visuo-attentional training
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Substance Abuse, Executive Dysfunction
Working Memory Training in Adults With Substance Abuse and Executive Function Deficits.
The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse…
- Conditions
- Substance Abuse, Executive Dysfunction, Anxiety, Depression
- Trial name
- NCT02068261
- Testing
- Computerized Cogmed working memory training, Treatment as usual
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Örebro Läns Landsting
Acquired Brain Injury, Alexia
Treatment for Reading and Writing Deficits Following Acquired Brain Injury
Many people with acquired brain injuries have deficits in reading decoding, reading comprehension, and written expression. Alexia is a phenomenon in which a person who previously could read has trouble doing so after having…
- Conditions
- Acquired Brain Injury, Alexia, Agraphia
- Trial name
- NCT03662243
- Testing
- Multicomponent reading and writing treatment
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Quality Living, Inc.
Reading Disability, Reading Problem
The Role of Knowledge Retrieval in Inference-making
This project will (a) examine the relationship between knowledge retrieval and inferencing; (b) determine the effectiveness of an intervention that improves knowledge retrieval and inferencing among struggling readers; and (c)…
- Trial name
- NCT05692973
- Testing
- Role of Knowledge Retrieval, Inference Intervention
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- William Jewell College
Dyslexia
Study of Hierarchy of Afferents in Postural Control of Children With Dyslexia
The purpose is to determine the hierarchy of sensory afferents according to different forms of dyslexia in children. The secondary purpose is to determine sensitive and sufficiently specific posturographic indexes for standard…
- Trial name
- EQUIDYS (NCT02879786)
- Testing
- Posturographic tests, Questionnaire of motion sickness susceptibility
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Dyslexia
Sensory Integration Therapy in Children With Dyslexia
The aim of this study is to examine the sensory and functional effects of sensory integration therapy in children with dyslexia according to the Model of Human Occupation (MOHO).
- Trial name
- Dyslexia (NCT04740853)
- Testing
- Sensory Integration Therapy+Special Education
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Biruni University
Asperger's Syndrome, Dyslexia
My Scrivener® - Measuring Effectiveness and Dose Response in Children
This study will assess whether a computer haptic peripheral device programmed to provide repetitive motion training is as effective as the same repetitive motion training provided by a human being.
- Conditions
- Asperger's Syndrome, Dyslexia, Cerebral Palsy, Attention Deficit Disorder
- Trial name
- NCT00919906
- Testing
- My Scrivener(R)
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Obslap Research LLC
Developmental Dyslexia
V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial direct current stimulation…
- Trial name
- NCT05972200
- Testing
- Active HD-tDCS over V5/MT, Active HD-tDCS over V1
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Dyslexia, Developmental
Poly-unsaturated Fatty Acids and Developmental Dyslexia
Poly-unsaturated fatty acids (PUFAs) represent a component of lipids that covers a relevant role in human diet and biological functions such as provision of energy, functionality of cell membranes and tissue metabolism.
- Trial name
- NCT04287530
- Testing
- Poly-unsaturated fatty acids supplementation, Neuropsychological intervention
- Where
- 2 sites in Italy
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Reading Disability, Anxiety
Evidence-Based Interventions to Enhance Outcomes Among Struggling Readers
Despite decades of research on reading disabilities, little is known about improving reading in the middle grades (i.e., grades 3-6) and advancements have been hindered by the narrow focus on reading problems alone without…
- Trial name
- NCT04059939
- Testing
- Reading, Anxiety Management, Classroom Business as Usual
- Where
- United States
- Volunteers
- 542 people
- Sponsor
- Boston University Charles River Campus
ADHD, Dyslexia
Dual Executive Function Training Package
Executive function (EF) refers to the cognitive processes that enable goal-directed regulation of thoughts, emotions, and behaviours.
- Conditions
- ADHD, Dyslexia, Autism
- Trial name
- NCT07262853
- Testing
- Executive Function Training
- Where
- Hong Kong
- Volunteers
- 288 people
- Sponsor
- Education University of Hong Kong
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Language Impairment, Hearing Loss
Characterization of Auditory Processing Involved in the Encoding of Speech Sounds
The ability to encode the speech signal is determined by ascending and descending auditory processing. Difficulties in processing these speech signals are well described at the behavioral level in a specific language disorder.
- Trial name
- PRODIPRICIDE (NCT02574299)
- Testing
- E-learning, Hearing aids fitting
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Dyslexia, Aging Problems
Neuroplasticity of Multisensory Cortical Areas Induced by Musical Training: a Translational Approach (MusicPlast)
Exploiting recent methodological advancements, several neuroimaging studies suggested that multisensory integration emerges from a dynamic interplay of distributed regions operating in large-scale networks.
- Trial name
- MusicPlast (NCT03786185)
- Testing
- MusicPlast, MusicPlast Control
- Where
- Greece
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Attention Deficit Hyperactivity Disorder, Dyslexia
Effects of Atomoxetine on Brain Activation During Attention & Reading Tasks in Participants With ADHD & Comorbid Dyslexia
This study will evaluate the effects of atomoxetine on brain activation during attention and reading tasks via functional Magnetic Resonance Imaging (fMRI) in participants ages 10 to 16 years old with ADHD and comorbid dyslexia
- Trial name
- NCT00716274
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Eli Lilly and Company
Dyslexia
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dyslexia
This study aims to determine whether levodopa, in combination with a high frequency training of (grammatical) rules, is effective in boosting learning success in healthy subjects and whether this kind of training in combination…
- Trial name
- NCT00111371
- Testing
- Levodopa
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster