Clinical trials: sponsored by Charite University, Berlin, Germany
Vaccination Knowledge and Acceptance, Informed Vaccine-decision Making
Assessment of Communication Interventions on Vaccination Knowledge and Acceptance
An online randomized controlled trial (RCT) examining the effectiveness of communication measures regarding TBE vaccination in the European context and yellow fever vaccination in the South American context on an informed…
- Trial name
- Y4F WP5/3 (NCT07921121)
- Testing
- Intervention group 1, Intervention group 2, Control format (vaccine check)
- Where
- Germany
- Volunteers
- 1,524 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy
Impact of Propionic Acid on Regulatory T Cell Function in Healthy Adults ( Pro-Health)
Pro-Health is a single-center, double-blind, randomized and placebo-controlled intervention study in healthy adults. The investigators address the effect of a dietary food supplementation of propionic acid on the immune system…
- Trial name
- Pro-Health (NCT06198374)
- Testing
- Sodium propionate
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cancer
AI-generated Treatment Recommendations in Precision Oncology
Non-interventional study to assess the non-inferiority of AI-generated treatment recommendations for precision oncology. Molecular tumor profiles will be assessed by local AI models to identify treatment options.
- Trial name
- AI-PRIME (NCT07897110)
- Testing
- large language model (non-interventional)
- Where
- Germany
- Volunteers
- 191 people
- Sponsor
- Charite University, Berlin, Germany
Critical Illness, Ultrasound
Core Competencies in General Intensive Care Ultrasound (GenIUS): a Delphi Study
This study using a Delphi methodology, and involving international experts, will help define a training curriculum for core competencies for general intensive care ultrasound practice.
- Conditions
- Critical Illness, Ultrasound, POCUS, Training
- Trial name
- NCT07917988
- Testing
- Delphi procedure
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario de Castellón
CKD (Chronic Kidney Disease) Stage 5D
Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD
Pro-Kids is a multi-center, double-blind, randomized and placebo-controlled intervention study in children with chronic kidney disease.
- Trial name
- Pro-Kids (NCT05858437)
- Testing
- Sodium propionate
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Charite University, Berlin, Germany
Postoperative Cognitive Deficit (POCD), Neurocognitive Disorders
International Observational Study on Perioperative Cognitive Trajectories (POCD Census International/PCI)
The purpose of this international, multi-centre observational study is to describe perioperative cognitive changes (pre-existing neurocognitive disorder [NCD], postoperative delirium [POD] and Postoperative Cognitive Dysfunction…
- Trial name
- NCT03540433
- Where
- 3 sites in Germany
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Pregnancy, Antenatal Depression
HappyMums Mobile Application Study
The goal of this study is to investigate whether pregnant people at risk of, or currently suffering from antenatal depression, find it acceptable to use the 'HappyMums' mobile application during their pregnancy.
- Trial name
- HappyMums (NCT06578845)
- Where
- 7 sites in Croatia, Finland and 4 more
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- King's College London
Kidney Cancers, Prostate Cancer
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
The COMFORT study will evaluate an artificial intelligence-based platform developed to support the clinical assessment of kidney and prostate cancer.
- Trial name
- COMFORT (NCT07888322)
- Testing
- Medical Reading, AI assisted Medical reading
- Where
- 6 sites in Germany, Greece and 2 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Congenital Heart Disease in Children
Evaluation of Preoperative Preparation in Children Undergoing Cardiac Surgery or Catheterization
Children undergoing cardiac surgery or cardiac catheterization often experience significant stress and anxiety during the preoperative period.
- Trial name
- GETREADY (NCT07414251)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Osteoporosis, Inflammatory Rheumatism
Glucocorticoid-induced Osteoporosis in Patients With Chronic Inflammatory Rheumatic Diseases or Psoriasis
Glucocorticoids remain to be among the most important and most frequently used anti-inflammatory and immunosuppressive or immune-modulatory acting drugs to treat rheumatic (and other) diseases.
- Trial name
- Rh-GIOP (NCT02719314)
- Testing
- Glucocorticoid treatment
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Prof Dr Frank Buttgereit
Adjacent Segment Disease, Lumbar Spinal Stenosis
Surgical Treatment of Adjacent Segment Stenosis
The goal of this clinical trial is to learn whether microdecompression alone is as effective as decompression with extension of fusion surgery in patients with symptomatic adjacent segment stenosis after previous lumbar fusion…
- Trial name
- STASS (NCT07661199)
- Testing
- Microsurgical Decompression with Extension of Fusion, Microsurgical Decompression Alone
- Where
- Germany
- Volunteers
- 338 people
- Sponsor
- Charite University, Berlin, Germany
ALS (Amyotrophic Lateral Sclerosis), SMA - Spinal Muscular Atrophy
Register for Medical Data, Functional Scales, and Care Outcomes in ALS, SMA, and Other Motor System Disorders
This observational registry collects existing medical and routine care data from people with amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and other motor system disorders.
- Conditions
- ALS (Amyotrophic Lateral Sclerosis), SMA - Spinal Muscular Atrophy, Spinal Cord Diseases, Central Nervous System Diseases
- Trial name
- NCT07900672
- Testing
- Standard of Care (Investigator Choice)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Ambulanzpartner Soziotechnologie APST GmbH
Rett Syndrome
Technology-supported Motor Rehabilitation for People With Rett Syndrome
This study focuses on improving purposeful arm use while simultaneously reducing engagement in stereotypies. It is typically expected that the training period for this study will last about 6 months.
- Trial name
- TeMoRett (NCT07418905)
- Testing
- computer gaming
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Georgetown University
Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
This is an observational (non-interventional), prospective, cohort study that will collects data from patients diagnosed with relapsed or refractory acute myeloid leukemia afferent to the participanting clinical sites
- Trial name
- IMPACT STREAM (NCT06459024)
- Testing
- Registration into the STREAM platform
- Where
- 41 sites in Germany, Italy and 5 more
- Volunteers
- 4,000 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Acute Myeloid Leukemia, Relapse/Recurrence
IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.
This is a multicenter, randomized, open-label, pragmatic low intervention clinical trial comparing high intensity reinduction chemotherapy with low intensity therapies in 1st or 2nd relapse Acute Myeloid Leukemia.
- Trial name
- IMPACT-AML (NCT06713837)
- Testing
- High intensity therapies, Low intensity therapies
- Where
- 51 sites in Czechia, Germany and 6 more
- Volunteers
- 339 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
B-Cell Acute Lymphoblastic Leukaemia
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020)
The IntReALL BCP 2020 study aims to review recent developments and findings regarding chemoimmunotherapy with inotuzumab and immunotherapy with blinatumomab and to increase the use of promising new immunotherapeutic drugs as…
- Trial name
- NCT07476729
- Testing
- Inotuzumab ozogamicin (INO), Blinatumomab
- Where
- 21 sites in Austria, Belgium and 19 more
- Volunteers
- 750 people
- Sponsor
- Charite University, Berlin, Germany
Postoperative Delirium
Digitalized Clinical Decision Support for the Prevention of Postoperative Delirium (POD)
The project aims to improve patient safety, reduce barriers to the implementation of current guideline recommendations, reduce workload in clinics, increase efficiency in work processes and close gaps in care.
- Trial name
- NCT06445153
- Testing
- Intervention with clinical decision support system
- Where
- 4 sites in Germany
- Volunteers
- 844 people
- Sponsor
- Charite University, Berlin, Germany
Food Allergy, Food Allergy Peanut
EPAP, Interviewstudy
The goal of this observational study is to learn about repetitive anaphylactic reactions in food allergic patients and to compare the frequency of repetitive reactions between different elicitors in food allergic patients.
- Conditions
- Food Allergy, Food Allergy Peanut, Allergy, Anaphylactic Shock
- Trial name
- NCT06192914
- Where
- Germany
- Volunteers
- 322 people
- Sponsor
- Charite University, Berlin, Germany
Mental Disorder, Physical Activity
Physical Activity Recommendation Behaviour in German Psychiatrists
The purpose of this study is to examine the physical activity recommendation behaviour, beliefs, barriers and exercise participation in German psychiatrists working with patients with mental disorders.
- Trial name
- NCT04165720
- Testing
- Online questionnaire
- Where
- Germany
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Mental Disorder, Burnout, Caregiver
Professional Quality of Life in German Psychiatrists
The purpose of this study is to assess professional quality of life in German psychiatrists working with patients with mental disorders.
- Conditions
- Mental Disorder, Burnout, Caregiver, Burnout, Professional
- Trial name
- NCT04165733
- Testing
- Online questionnaire
- Where
- Germany
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
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