Clinical trials: sponsored by University of British Columbia
Medical Device, User-Computer Interface
VitalPAD: an Intelligent Monitoring and Communication Device to Optimize Safety in the PICU
The VitalPAD is a unified, portable and intelligent device that integrates information from multiple patient monitors, mechanical ventilators, infusion pumps and clinical information systems on a mobile platform.
- Conditions
- Medical Device, User-Computer Interface, Critical Care, Physiologic Monitoring
- Trial name
- NCT02970903
- Testing
- VitalPAD, Traditional tools
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Inflammatory Bowel Disease, Crohn's Disease
IDeaL Pilot Study - Infliximab Dose to Level: Pilot Study
Crohn's disease (CD) is a lifelong condition of inflammation in the bowel. CD can affect any part of the gastrointestinal tract from mouth to anus.
- Trial name
- IDeaL (NCT02847884)
- Testing
- Infliximab
- Where
- 2 sites in Canada
- Volunteers
- 28 people
- Sponsor
- University of Alberta
Healthy
UVB: Skin to Gut Study
This research will explore the potential effects of Narrow-Band Ultra Violet B (NB-UVB) radiation on the intestinal microbiota composition and confirm a regulatory skin-to-gut axis during baseline conditions.
- Trial name
- NCT03962673
- Testing
- NB-UVB light exposure
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anemia, Iron Deficiency
Is Iron Deficiency the Cause of Anemia Among Women in Cambodia?
Globally, the most common cause of anemia is thought to be iron deficiency anemia (IDA). This was assumed to be the major cause of anemia in Cambodia, because Cambodian diets, which consist mainly of rice, lack iron-rich animal…
- Conditions
- Anemia, Iron Deficiency, Hemoglobin Disorder, Infection
- Trial name
- NCT02481375
- Testing
- Multiple micronutrients, Iron
- Where
- Cambodia
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sleep, Aging
Buying Time: Improving Sleep to Promote Cognitive Function in Older Adults
The purpose of this study is to investigate whether a comprehensive group education combined with a lifestyle "activation" program that includes (a) sleep hygiene course, (b) physical activity promotion, and (c) bright light…
- Trial name
- NCT02926157
- Testing
- Life Style and Sleep Intervention
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Mild Cognitive Impairment
Cognitive Brain Training in Older Adults
The investigators will conduct a 8-week proof-of-concept randomized controlled trial to provide preliminary evidence of efficacy of Fit Brains (Rosetta Stone Canada) training -- a mobile cognitive training program -- on cognitive…
- Trial name
- NCT02564809
- Testing
- Fit Brains Training, Exercise + Fit Brains Training, Balanced And Tone
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Paroxysmal Atrial Fibrillation
Cryoballoon vs. Irrigated Radiofrequency Catheter Ablation: Double Short vs. Standard Exposure Duration
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with reductions in quality of life, functional status, cardiac performance, and overall survival.1 Catheter ablation, which is centered on…
- Trial name
- CIRCA-DOSE (NCT01913522)
- Testing
- Pulmonary Vein Isolation
- Where
- Canada
- Volunteers
- 348 people
- Sponsor
- University of British Columbia
Chronic Rhinosinusitis (Diagnosis), Asthma
Unified Airway Model
Chronic rhinosinusitis (CRS) impacts approximately 5% of Canadians. CRS patients suffer from a combination of symptoms that include facial pain, nasal obstruction, hyposmia and mucopurulence discharge.
- Trial name
- NCT03937427
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Idiopathic Membranous Nephropathy
MEmbranous Nephropathy Trial Of Rituximab
The primary outcome of this study is to determine whether or not the B cell targeting with Rituximab is non-inferior or more effective than Cyclosporine in inducing long term remission of proteinuria.
- Trial name
- MENTOR (NCT01180036)
- Testing
- Rituximab, Cyclosporine
- Where
- 21 sites in United States, Canada
- Volunteers
- 130 people
- Sponsor
- Mayo Clinic
Domestic Violence
Effectiveness of an Online Safety Tool for Canadian Women Experiencing Intimate Partner Violence
The purpose of this study is to assess the effectiveness of an interactive, online safety decision aid among diverse Canadian women who are experiencing intimate partner violence (IPV).
- Trial name
- NCT02258841
- Testing
- Setting Priorities for Safety, Danger Assessment, Personalized Action Plan
- Where
- 3 sites in Canada
- Volunteers
- 462 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Orthostatic Hypotension, Postural Hypotension
Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury
Individuals with acute cervical spinal cord injury (SCI) can suffer from an excessive and prolonged fall in blood pressure when assuming an upright position, such as transitioning from lying to sitting or standing, a condition…
- Trial name
- NCT01874782
- Testing
- transcranial electrical stimulation
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of British Columbia
Multiple Sclerosis
PET Study in Multiple Sclerosis
While both conventional and advanced MRI techniques offer important insights into MS pathophysiology, important aspects of this inflammatory disorder are undetectable with existing MRI technology.
- Trial name
- NCT03787446
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postoperative Pain, Anesthesia, Conduction
PANDA-Regional Feasibility Study of a Smartphone Pain Management Application
Despite the numerous benefits of peripheral nerve blocks (PNBs) over general anesthesia (GA) in a variety of surgical procedures, PNBs can be associated with increased post-operative pain if pain medications are not taken…
- Trial name
- NCT03369392
- Testing
- Panda application
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ketones, Dietary Supplements
Exogenous Ketones and Glucose Tolerance
The ketone body beta-hydroxybutyrate is produced during prolonged fasting or when endogenous carbohydrate stores are depleted and can be used as an alternative fuel source.
- Trial name
- NCT03461068
- Testing
- Ketone monoester
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
MCT Oil Supplementation
The Effect of Raising Ketones Directly With MCT Oil on Inflammation in Healthy Young Adults
Ketogenic diets are gaining support as a method to lower inflammation within the body, but studies have not been able to show the way by which this occurs.
- Trial name
- NCT03460444
- Testing
- MCT Oil Supplementation
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Respiratory Distress Syndrome, Newborn, Chronic Lung Disease of Newborn (Diagnosis)
Diaphragmatic Electrical Activity in Preterm Infants on Non-Invasive Ventilation
Preterm babies have immature lungs and frequent pauses in their breathing which often necessitates breathing support. Nasal Continuous Positive Airway Pressure (CPAP) is one of the most commonly used tools but does not always…
- Trial name
- NCT03422549
- Testing
- Drager VN500 Ventilator
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Transplantation Infection
Prevention of Healthcare Associated Infections in Bone Marrow Transplant Patients
This study involves sampling bone marrow transplant patients, hospital workers and the patient room for microbes using swabs and other techniques.
- Trial name
- NCT02463214
- Testing
- Engineered Room
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy
The Influence of Intranasal Oxytocin on Communication
This study investigates whether oxytocin, a neuropeptide known for its role in social bonding, influences the outcomes of persuasive communications and several primary evolutionary goals.
- Trial name
- NCT02415920
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia, Regional, Pain, Postoperative
Pectoral-Intercostal Fascial Plane Block Study
Pain along the sternum following opening of the chest cavity, also known as post-sternotomy pain (PSP), is a common complication after heart surgery that is associated with several negative side effects.
- Trial name
- PIFB (NCT03729635)
- Testing
- Pectoral-intercostal fascial plane block (PIFB)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Severe Sepsis, Septic Shock
Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock
Sepsis is a significant cause health care expenditure and carries an extremely high rate of morbidity and mortality if not treated appropriately.
- Conditions
- Severe Sepsis, Septic Shock, Bacteremia
- Trial name
- NCT01867905
- Where
- 7 sites in United States, Canada
- Volunteers
- 330 people
- Sponsor
- University of British Columbia
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