Clinical trials: enrolling by invitation
Gynecologic Surgery, General Anesthesia
Long-term Follow-up of Bio-signals and Quality of Recovery Following Implementation of ERAS Based on the Mobile Application
The goal of this clinical trial is to evaluate the effect of an Enhanced Recovery After Surgery (ERAS) protocol in patients undergoing gynecologic laparoscopic or robotic surgery under general anesthesia.
- Trial name
- NCT07868952
- Testing
- Enhanced Recovery After Surgery, Usual Care
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Wonju Severance Christian Hospital
Poor Quality Sleep
SHLH for Urban Adolescents (Efficacy Trial)
The overall study goal is to test the efficacy and cost-effectiveness of Sleeping Healthy, Living Healthy (SHLH), a novel intervention that combines healthy sleep practices with mind-body integrative health (MBIH) approaches to…
- Trial name
- NCT07893015
- Testing
- Sleeping Healthy, Living Healthy, Sleep for Teens
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Columbia University
Breast Cancer
Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA Study
TOL2506A (OVELIA) is a Phase 3, single arm, open-label study evaluating the effectiveness of TOL2506 in suppressing ovarian function in premenopausal women with HR+, HER2-negative breast cancer and men with HR+ breast cancer.
- Trial name
- NCT05645536
- Testing
- TOL2506, Tamoxifen, Letrozole tablets
- Where
- 46 sites in United States, Argentina and 4 more
- Volunteers
- 250 people
- Sponsor
- Tolmar Inc.
Hematologic Malignancies, Solid Tumors
Follow-Up for Study Participants Treated With an Allogeneic CAR T Cell Product
An observational, long-term follow up (LTFU) study of participants who received an allogeneic CAR T product in a prior clinical study.
- Trial name
- NCT06925685
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Allogene Therapeutics
Medication Adherence
Investigation of a Patient Support Intervention for Statin Medication Adherence
Statins have been demonstrated to significantly reduce the risk of cardiovascular disease, but adherence to these medications is suboptimal.
- Trial name
- NCT06972979
- Testing
- Text Message Gamification and Remote Support
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Diabetes Mellitus
Multicenter Assessment of the Pancreas in Type 1 Diabetes
The overall goal of this research is to develop and validate standard operating procedures (SOP) to assess the human pancreas in individuals with type 1 diabetes (T1D) and other forms of diabetes using advanced, quantitative…
- Trial name
- MAP-T1D (NCT03585153)
- Testing
- Non-contrast magnetic resonance imaging
- Where
- 5 sites in United States, Australia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Rheumatoid Arthritis (RA)
Nutrition in Rheumatoid Arthritis
Background: Individuals with Rheumatoid Arthritis (RA) often experience persistent symptoms such as pain and stiffness despite modern pharmacological treatments. They also have an increased risk of cardiovascular disease.
- Trial name
- NUTRA (NCT06831331)
- Testing
- Healthy diet based on NNR2023, Control/waiting-list
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Vastra Gotaland Region
Perimenopause, PMDD
Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause
Transcutaneous Auricular Neurostimulation (tAN) will be administered to women with premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and perimenopause.
- Trial name
- NCT07688720
- Testing
- transcutaneous auricular neurostimulation (tAN)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Texas Christian University
Psoriatic Arthritis
Combined High-Intensity Aerobic Training and Resistance Training in Psoriatic Arthritis
The goal of this randomised controlled trial is to evaluate the effects of a 12-week intervention comprising high-intensity interval aerobic training and strength training on cardiovascular function, metabolic health profile and…
- Trial name
- PsA-HIIT (NCT07352696)
- Testing
- Exercise program
- Where
- 2 sites in Sweden
- Volunteers
- 88 people
- Sponsor
- Vastra Gotaland Region
Gout Initiating Urate-loweringUrate-lowering Therapy
The Remote Monitoring of Gout Study
The goal of this clinical trial is to: compare a new digital self-management treatment strategy to usual care, for patients with gout receiving urate lowering therapy in specialist healthcare.
- Trial name
- ReMonit Gout (NCT06822933)
- Testing
- Urika, Nurse-led follow-up with telephone consultations.
- Where
- Norway
- Volunteers
- 168 people
- Sponsor
- Diakonhjemmet Hospital
Patients Treated at the Neurosurgery Department
Patient Registry of the Neurosurgery Department
The investigators record all indications, treatments and outcomes from patients treated at the Neurosurgery Department. Trial with surgical intervention
- Trial name
- patregNCH (NCT01628406)
- Testing
- Treatment at the neurosurgery departement
- Where
- Switzerland
- Volunteers
- 24,000 people
- Sponsor
- University of Zurich
Duchenne Muscular Dystrophy
An Observational Study Comparing Delandistrogene Moxeparvovec (ELEVIDYS) With Standard of Care in Participants With Duchenne Muscular Dystrophy
This is a multicenter, prospective, observational Phase 4 study including a post marketing safety requirement, designed to collect both medical history data and prospective data on Duchenne muscular dystrophy (DMD) treatment…
- Trial name
- ENDURE (NCT06270719)
- Testing
- Delandistrogene Moxeparvovec, Standard of Care
- Where
- 29 sites in United States
- Volunteers
- 500 people
- Sponsor
- Sarepta Therapeutics, Inc.
Obesity, Obesity & Overweight
Real-world Exploration of Digital iNnovation in the Management of Excess Weight
This is a real-world study. The purpose of this research is to explore whether a new National Institute for Health and Care Excellence (NICE)-approved digital weight-management model of care can improve health service delivery…
- Trial name
- RENEW (NCT07283978)
- Testing
- Digital Weight Management Programme
- Where
- United Kingdom
- Volunteers
- 580 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Gastrointestinal Neuroendocrine Carcinoma, Adjuvant Treatment
Oxaliplatin-Based Adjuvant Therapy for Gastrointestinal Neuroendocrine Carcinoma**
Patients with pathologically-confirmed gastrointestinal neuroendocrine carcinoma will be enrolled, to explore the efficacy and safety of oxaliplatin-based doublet chemotherapy in the adjuvant treatment of gastrointestinal…
- Conditions
- Gastrointestinal Neuroendocrine Carcinoma, Adjuvant Treatment, Resection
- Trial name
- NCT07891572
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Peking Union Medical College Hospital
Schizophrenia Disorder, Schizoaffective Disorder
Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization
This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance…
- Conditions
- Schizophrenia Disorder, Schizoaffective Disorder, Bipolar Disorder (BD), Substance Use Disorder (SUD)
- Trial name
- NCT07130500
- Testing
- Financial incentives for adherence to long-acting injectable medication, Standard of care with monthly surveys
- Where
- 6 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Stanford University
Total Knee Arthroplasty
Smartphone Video-Based AI Gait Analysis Reports to Support Remote Follow-up After Total Knee Arthroplasty
This study evaluates whether an artificial intelligence (AI)-assisted gait report generated from smartphone walking videos can support remote follow-up after total knee arthroplasty (TKA).
- Trial name
- NCT07892248
- Testing
- Smartphone Video-Based AI Gait Analysis, video recorded on a mobile phone (assessed by doctors)
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Prehabilitation, Cardiac Surgery
Feasibility of Physical Prehabilitation for High-Risk Patients Undergoing Cardiac Surgery Via Sternotomy
Rationale Cardiac surgery via median sternotomy carries an elevated risk of postoperative complications and delayed functional recovery.
- Conditions
- Prehabilitation, Cardiac Surgery, Risk Assesment, Aortic Valve
- Trial name
- PREPA-STER (NCT07893184)
- Testing
- Physical Prehabilitation Intervention
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Vasodilatory Shock
Synthetic Angiotensin II/Giapreza in Pediatric Patients With Refractory Hypotension
The goal of this clinical trial is to determine the safety and efficacy of Angiotensin-II in the treatment of pediatric patients in fluid refractory vasodilatory shock.
- Trial name
- NCT07212686
- Testing
- Angiotensin-II
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Surgery
Premedication Gastric Ultrasound
The primary objective of this study is to assess gastric volume in fasted children using ultrasound before and after drinking premedication.
- Trial name
- NCT04130022
- Testing
- Point-of-Care Ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kevin Spellman
Cancer
Improving Goals of Care Conversations Between Doctors and Young Adults With Cancer
The purpose of this study is to adapt a goals of care communication tool, called Jumpstart, for adolescent and young adult cancer patients (also called AYAC).
- Trial name
- NCT07855484
- Testing
- Jumpstart GOCC intervention
- Where
- 7 sites in United States
- Volunteers
- 118 people
- Sponsor
- Memorial Sloan Kettering Cancer Center