Clinical trials: sponsored by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Congenital Heart Disease (CHD), Ventricular Septal Defects (VSD)
Early Warning of Structural Complications in Perimembranous VSD
The goal of this observational study is to develop and test a AI-based prediction model for children with perimembranous ventricular septal defect, also called PMVSD.
- Trial name
- NCT07662343
- Where
- China
- Volunteers
- 11,683 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Metabolic Dysfunction-associated Fatty Liver Cirrhosis
Fuzheng Huayu Tablets for Metabolic Dysfunction-Associated Fatty Liver Cirrhosis (Compensated): A Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Study
This is a multicenter, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of Fuzheng Huayu Tablets in patients with metabolic dysfunction-associated fatty liver cirrhosis…
- Trial name
- NCT07663643
- Testing
- Fuzheng Huayu Tablets
- Volunteers
- 459 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Glycogen Storage Disease Type IB
Efficacy and Safety of Empagliflozin in GSD-Ib Patients
Empagliflozin Treatment of GSD-1b patients
- Trial name
- NCT05960617
- Testing
- Empagliflozin
- Where
- China
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Chronic Kidney Disease-Associated Pruritus in Hemodialysis
Clinical Study on the Efficacy and Safety of Nalfurafine Hydrochloride Orally Disintegrating Tablets in Treating Pruritus in Patients Undergoing Maintenance Hemodialysis
This is a randomized, open-label, multi-center clinical study aimed at evaluating the efficacy and safety of 12 weeks of nalfurafine hydrochloride administration in the treatment of pruritus in patients undergoing maintenance…
- Trial name
- NCT07650851
- Testing
- Nalfurafine Hydrochloride, Basic treatment
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese PLA General Hospital
Autism Spectrum Disorder
Transcranial Temporal Interference Stimulation for Children With Autism Spectrum Disorders
The goal of this single-blinded, randomized controlled trial is to assess the safety, tolerability, and feasibility of tTIS for children with ASD.
- Trial name
- NCT07625748
- Testing
- transcranial Temporal Interference Stimulation
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Intracranial Dural Arteriovenous Fistula
Multicenter Registry Study of Patients With Intracranial Dural Arteriovenous Fistulas in China
This multicenter registry study aims to clarify the incidence trends of intracranial dural arteriovenous fistulas (IDAVF) and spinal dural arteriovenous fistulas (SDAVF) in China, evaluate current treatment patterns, and…
- Trial name
- DREAM (NCT07604688)
- Testing
- endovascular
- Where
- China
- Volunteers
- 10,050 people
- Sponsor
- Xuanwu Hospital, Beijing
Parkinson Disease, Idiopathic
Clinical Trail of Transcranial MR-guided Focused Ultrasound in the Treatment of Motor Symptoms in Patients With Parkinson' Disease
Randomized, double-blind, self-cross-over control (After the first visit, patients are divided into two groups, randomly receiving real stimulation/placebo stimulation.
- Trial name
- NCT06639945
- Testing
- transcranial MR-guided focused ultrasound
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Autism Spectrum Disorder
Efficacy and Mechanism of Repetitive Transcranial Magnetic Stimulation in Children With Autism Spectrum Disorders
This study is a prospective, multicenter, randomized, single-blind controlled trial to enroll 200 children with autism spectrum disorders (ASD).
- Trial name
- NCT05927792
- Testing
- repeated transcranial magnetic stimulation (continuous theta-burst stimulation)
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Colonoscopy: Bowel Preparation, IBD - Inflammatory Bowel Disease
Pre-Packaged Low-Residue Diet Assisting Bowel Preparation in Patients With Inflammatory Bowel Disease
The primary objectives of this study are as follows: 1.To evaluate the efficacy of Maifu Changqing® Complete Nutritional Formula Powder in bowel preparation for colonoscopy among inflammatory bowel disease (IBD) patients;2.To…
- Trial name
- NCT07165470
- Testing
- pre-packaged low-residue diet for bowel preparation
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Changhai Hospital
IBD (Inflammatory Bowel Disease), Colonoscopy
Analysis of Factors Influencing the Quality of Bowel Preparation Before Colonoscopy in IBD Patients
The primary objectives of this project are twofold. On the one hand, it aims to investigate the current status of bowel preparation protocols and their quality in IBD patients undergoing colonoscopy, particularly focusing on the…
- Conditions
- IBD (Inflammatory Bowel Disease), Colonoscopy, Colonoscopy: Bowel Preparation
- Trial name
- NCT07335705
- Testing
- Standard Pre-colonoscopy Bowel Preparation Protocol
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Heart Failure, Intraventricular Block
A Randomized Controlled Trial of LOT-CRT Versus conventionaL BiVP in Heart Failure Patients With NICD
BATTLE study has been designed as a prospective, multi-center, randomized, controlled trial. This study will enroll 83 patients with chronic heart failure accompanied by intraventricular block (NICD) over an estimated recruitment…
- Trial name
- BATTLE (NCT06061627)
- Testing
- LOT-CRT group, BiVP group
- Where
- China
- Volunteers
- 86 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
IBD (Inflammatory Bowel Disease), Colonoscopy
Pre-packaged Low-residue Diet for Bowel Preparation in Patients With Inflammatory Bowel Disease
The primary objectives of this project are twofold: firstly, to evaluate the role of Maifu Changqing® Complete Nutrition Formula Powder in bowel preparation for colonoscopy in patients with IBD; and secondly, to enhance the…
- Conditions
- IBD (Inflammatory Bowel Disease), Colonoscopy, Colonoscopy: Bowel Preparation
- Trial name
- NCT07353853
- Testing
- pre-packaged low-residue diet for bowel preparation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Changhai Hospital
Solid Tumor Cancer, Solid Tumor Cancer Treatment With Immunotherapy
Phase I, Open-labeled, Dose-escalation, Dose-expansion Study Evaluating the Safety, Tolerance, Pharmacokinetics, and Activity of IUAb190708 in Patients With Advanced or Recurrent Solid Tumors
This study is to evaluate a novel cytotoxic anti-PD-L1, IUAb190708, for the treatment of tumor
- Trial name
- NCT07584954
- Testing
- IUAb190708, a cytotoxic antibody
- Where
- 6 sites in China
- Volunteers
- 90 people
- Sponsor
- Jun Zhou
Adolescent Idiopathic Scoliosis (AIS)
Detection of Scoliosis
This study aims to evaluate whether plantar pressure data collected during standing and walking can be used with machine learning to support early detection of scoliosis in young people.
- Trial name
- NCT07581015
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University College, London
Migraine
A Phase II Study of NB001 for Acute Migraine Treatment
The goal of this observational study is to Evaluate the Efficacy and Safety of NB001 for the Acute Treatment of Migraine in Adult patients diagnosed with migraine.
- Trial name
- Channel (NCT07577050)
- Testing
- Four tablets of NB001
- Volunteers
- 120 people
- Sponsor
- Chinese PLA General Hospital
Autism Spectrum Disorder
Efficacy of Bumetanide in Children With Autism Spectrum Disorder Guided by Peripheral Blood Biomarkers and Machine Learning Models
The objective of this study is to learn if bumetanide could alleviate the clinical symptoms in children with autism spectrum disorder (ASD), who has been predicted as high responders to bumetanide via a cytokine-based predictive…
- Trial name
- NCT07005414
- Testing
- Bumetanide, Treatment as usual (TAU)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fei Li
Treatment Outcome
99Tc-MDP Treatment for Knee Osteoarthritis
Osteoarthritis (OA) of knee is the most common form of arthritis in the world1e, and it has received growing attention in the society because of the increase of old age population, disabled people, and medical expenses from this…
- Trial name
- NCT02993029
- Testing
- 99Tc-MDP, Celecoxib
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Fetal Growth Restriction (FGR)
Melatonin and Perinatal Outcomes in MVM-Related Fetal Growth Restriction (MIMVMFGR)
The goal of this clinical trial is to evaluate the efficacy and safety of melatonin in the treatment of early-onset severe maternal vascular malperfusion-related fetal growth restriction (MVM-FGR), and to determine its effects on…
- Trial name
- MIMVMFGR (NCT07549295)
- Testing
- Melatonin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Defect
Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect
Cesarean section scar defect (CSD) is a novel recognized cause of postmenstrual abnormal uterine bleeding in women. No clinical guidelines have been issued for the management of CSD.
- Trial name
- NCT05205317
- Testing
- Metformin Hydrochloride Sustained-release Tablets, Vaginal repair
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
High-grade Serous Ovarian Cancer, Circulating Tumor DNA
CtDNA as a Novel Biomarker of Treatment Efficacy in Patients With Ovarian Cancer
This study is a prospective observational clinical trial. Patients who were diagnosed and treated for the first time were enrolled and their surgical pathology was confirmed to be high-grade serous ovarian cancer.
- Trial name
- NCT05027828
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine