Clinical trials: Phase not applicable
Renal Transplantation
Non-Invasive Biomarker Strategy Integrating Dd-cfDNA Versus Biopsy-Based Monitoring in Kidney Transplant Recipients
The investigator hypothesizes that the combined use of 1. non-invasive biomarkers including dd-cfDNA in peripheral blood predicting anti-donor immunological activation or quiescence with 2.
- Trial name
- EUTRAIN IMPACT (NCT04774575)
- Testing
- biomarker-guided strategy
- Where
- 8 sites in France, Germany and 2 more
- Volunteers
- 342 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Food Allergy in Children
Immunotherapy for Curing Toddlers With Severe Food Allergy - a Paradigm Shift From Passive to Active Treatment With Multi-allergen Oral Immunotherapy
The aim is to study whether a multiallergen oral immunotherapy (OIT) strategy with slow up-dosing and low treatment dose against food allergy in young children (0.5-3 years) is safe and effective, a method to cure food allergy…
- Trial name
- INFO-DK (NCT07899359)
- Testing
- OIT multiallergen powder
- Volunteers
- 80 people
- Sponsor
- Odense University Hospital
Urinary Incontinence
Augmenting Urinary Reflex Activity: Study 3
AURA-3 study (Augmenting Urinary Reflex Activity Study 3) is a single arm, short-duration (8 month) cohort follow up study of preceding interventional medical device study, AURA-2.
- Trial name
- AURA-3 (NCT06597994)
- Testing
- Amber UI system
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- Amber Therapeutics Ltd
Environmental Awareness, Ecological Footprint
Effect of AI-Based Image Generation on Children's Ecological Footprint Awareness
The aim of this study is to examine the effect of artificial intelligence-based image generation on children's ecological footprint awareness.
- Conditions
- Environmental Awareness, Ecological Footprint, Healthy Children
- Trial name
- NCT07898527
- Testing
- AI-Based Image Generation Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Androgenic Alopecia, Hair Loss/Baldness
Study to Evaluate Xtressé Gummy Supplement in Men With Androgenic Alopecia
The goal of this study is to determine if Xtresse' gummy is safe and may help regrow hair in men with androgenic alopecia (common pattern hair loss).
- Conditions
- Androgenic Alopecia, Hair Loss/Baldness, Hair Thinning
- Trial name
- NCT07637071
- Testing
- Xtressé Hair Growth Gummies
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Restore Biologics Holdings, Inc. dba Xtressé
Infraclavicular Vein Cannulation, Venous Cannulation
Right Versus Left Distal Axillary Vein Cannulation
Central venous cannulation is an essential procedure in the anaesthetic and critical care practice. Ultrasound has revolutionized the practice favoring the internal jugular cannulation to the other sites .Subcalvian vein…
- Trial name
- NCT06761326
- Testing
- Ultrasound guided right infraclavicular approach of subclavian vein cannulation, Ultrasound guided left infraclavicular approach of subclavian vein cannulation
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Alexandria University
Manual Wheelchair Use, Spinal Cord Injury
Comparison Between Objective Biomechanical Cost and Perceived Physical Demand in Manual Wheelchair Users During Propulsion Tasks
Wheelchair users must be able to move around freely and access public buildings and transport, but current accessibility standards (e.g.
- Trial name
- FFM (NCT07897214)
- Testing
- Instrumented Manual Wheelchair Propulsion Tasks (Motion Analysis and Instrumented Handrims), Concurrent Cognitive Task (Auditory-Verbal 2-back)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Keratinized Tissue Deficiency
Applying of Absorbable Dressing (Reso-Pac) on the Palatal Donor Site
The periodontal dressing was applied to the donor site of the free gingival graft on the palate to protect the site, reduce postoperative pain, and improve soft tissue healing in the palatal area.
- Trial name
- NCT07898735
- Testing
- Control group : Coe-pak, Study Group: Reso-pac
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Gaze Tracking
Quiet Eye Duration in Baseball
The purpose of this study is to measure the gaze movements of individuals as they watch videos of a baseball pitcher throwing pitches.
- Trial name
- NCT04289376
- Testing
- Gaze tracking - no intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Healthy
Development and Evaluation of Magnetic Resonance Imaging Acquisition and Analysis Methods
Magnetic resonance imaging (MRI) is a diagnostic imaging method with constant progress and improvement in the way the MRI images are obtained. Many of these advances involve changes to MRI software and hardware.
- Trial name
- NCT02091518
- Testing
- MR Screening Questionnaire, Magnetic Resonance Imaging Acquisition and Analysis
- Where
- United States
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Nursing Education
AI-Assisted Child Health Podcast Education for Nursing Students
This randomized controlled study will evaluate the effect of developing and implementing artificial intelligence (AI)-assisted child health podcasts for parents on nursing students' attitudes toward clinical practice and learning…
- Trial name
- NCT07899541
- Testing
- AI-Assisted Child Health Podcast Development and Implementation
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Multimorbidity, Integrated Care
TimelyCare - A Proactive Primary Care Model: Delivering the Right Care at the Right Time for Individuals at Risk of High Care Consumption
Healthcare systems face persistent challenges in providing coordinated, proactive care for individuals with complex health needs, resulting in high vulnerability to fragmented care, acute clinical deterioration, and frequent…
- Conditions
- Multimorbidity, Integrated Care, Primary Care Patients With Chronic Conditions, Coordination, Administrative
- Trial name
- NCT07899723
- Testing
- Timely Care,
- Where
- Sweden
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Coronary Microvascular Dysfunction, Coronary Microvascular Disease
Insulin Resistance and Coronary Microvascular Dysfunction in Patients With Myocardial Ischemia and Non-obstructive Coronary Artery Disease
The goal of this prospective study is to assess the correlation between coronary microvascular disfunction and insulin resistance in patients with INOCA.
- Conditions
- Coronary Microvascular Dysfunction, Coronary Microvascular Disease, Insulin Resistance
- Trial name
- IRIN (NCT06597851)
- Testing
- Thermodilution based assessment of coronary microcirculation, Hyperinsulinemic-euglycemic Clamp test
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Breast Cancer
Decision Support for Chemoprevention
The purpose of this study is to find out whether electronic tools that provide information and reminders to people at high risk for breast cancer and their healthcare providers can increase the use of medications, such as…
- Trial name
- NCT07899151
- Testing
- RealRisks Decision Aid
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Columbia University
Acute Ischemic Stroke and Transient Ischemic Attacks
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
Stroke can occur when a blood clot travels to the brain and blocks blood flow. In some patients, these blood clots may originate in the heart.
- Trial name
- SCOPE-CT (NCT07896889)
- Testing
- Cardiac CT Angiography
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
GTPS - Greater Trochanteric Pain Syndrome, Gluteal Tendinopathy
The HIP Self-management Study
The HIPS-study will be an observer blinded, single-centre, parallel-group randomized controlled trial (RCT). The main purpose of the study is: 1.
- Conditions
- GTPS - Greater Trochanteric Pain Syndrome, Gluteal Tendinopathy, Trochanteric Bursitis, Lateral Hip Pain
- Trial name
- HIPS (NCT06297148)
- Testing
- Self-management, Usual care
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Oslo University Hospital
Diabetes Type 2, Overweight or Obesity
Effect of the Thrive AI Health App on Lifestyle Behaviors and Quality of Life
The goals of this randomized trial is to learn: 1. If the Thrive AI Health app will help adults improve their everyday habits (diet, exercise, and sleep). 2.
- Trial name
- NCT07376655
- Testing
- App
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypertrophic Cardiomyopathy, Left Ventricular Outflow Obstruction
NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label Devices
This is an early study of a catheter-based minimally invasive procedure called SESAME to slice thick heart muscle as described below.
- Conditions
- Hypertrophic Cardiomyopathy, Left Ventricular Outflow Obstruction, Systolic Anterior Motion
- Trial name
- NCT07806149
- Testing
- SESAME Procedure
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Adolescent Idiopathic Scoliosis (AIS)
Protocol for a Randomized Controlled Trial of a Clinician-Supervised Home-School-Hospital-Linked Digital Health Platform-Supported Conservative Management Pathway for AIS
Adolescent idiopathic scoliosis (AIS) brings substantial physical and psychological burden to affected teenagers, and current conservative follow-up management is fragmented under routine clinical settings.
- Trial name
- NCT06314594
- Testing
- Routine Guideline-Based Conservative Care, Clinician-Supervised, Platform-Assisted Conservative Management
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Hangzhou Medical College
Delirium, Intensive Care Unit Delirium
Family-partnered Delirium Prevention, Detection, and Management in the ICU
Almost half of critically ill patients experience delirium. Delirium is associated with impaired cognition, mortality, and increased healthcare costs.
- Conditions
- Delirium, Intensive Care Unit Delirium, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- ACTIVATE (NCT07896356)
- Testing
- Standard of Care, Delirium Education, Prevention, and Management
- Where
- Canada
- Volunteers
- 1,344 people
- Sponsor
- University of Calgary