Clinical trials: completed, sponsored by University of Michigan
Constipation
Guideline to Implementation: A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipation
The study is being completed to test the pilot implementation of a rapid clinical care pathway for chronic constipation in the University of Michigan Gastroenterology clinic.
- Trial name
- NCT06352827
- Testing
- Survey
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Surgery, Analgesics, Opioids
Methods for Effective Disposal of Surplus Analgesics to Facilitate Elimination
The primary objective is to evaluate the difference in outcomes for mail-in vs. in-home disposal methods for leftover prescription opioids after discharge from surgery.
- Trial name
- MEDSAFE (NCT05991687)
- Testing
- In-home drug disposal pouch, Mail-in prepaid envelope
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Michigan
Obesity; Familial, Pregnancy Related
Maternal Metabolic and Molecular Changes Induced by Preconception Weight Loss and Their Effects on Birth Outcomes
Our hypothesis is that aggressive preconception weight loss in obese women will improve the metabolic health of the mother and the intrauterine environment.
- Trial name
- NCT03244722
- Testing
- Very-low energy Diet (VLED), Standard of care (SOC)
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pulmonary Embolism
Michigan Emergency Department Improvement Collaborative (MEDIC) Alert; Pulmonary Embolism (PE)
This study is a quality improvement project to evaluate health care management of pulmonary embolism (PE) patients. The researchers are testing an intervention to determine if it prevents unnecessary hospital admissions.
- Trial name
- NCT06312332
- Testing
- Pulmonary Embolism (PE) Care in Emergency Department (ED)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Michigan
Post Partum Depression
A Wearable Morning Light Treatment for Postpartum Depression
This study will test a consumer health light therapy device (Re-Timer) for women with postpartum depression to better understand how it affects mood and the body clock (also called the circadian clock).
- Trial name
- NCT04845347
- Testing
- Bright Light Therapy, Dim Light Therapy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of Michigan
LGBTQ, Racial Disparities
Lakota Family Acceptance Project
The goal of this open pilot trial (OPT) is to develop a Lakota-adapted Family Acceptance Project (LFAP) for Indigenous 2SLGBTQ+ youth and their caregivers.
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP OPT (NCT07326748)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hypertension
Building a Multidisciplinary Research Program to Address Hypertension Disparities: Exploring the Neurocognitive Mechanisms of a Self-Management Intervention for African American Women
The goal of this project is to develop and pilot test a research protocol to assess the influence of a health information behavior enhanced intervention on self-management, blood pressure control, and brain activity in African…
- Trial name
- NCT04266704
- Testing
- Sharing Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Inflammatory Bowel Diseases, Ulcerative Colitis
IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms
This research study is testing whether changes in sleep timing and morning light treatment may have an impact on symptoms related to inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT06094608
- Testing
- Morning light treatment, Treatment-as-usual
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Michigan
Chronic Migraine
Brief Interventions in Chronic Migraine
People with chronic migraine headaches face many challenges, including high levels of daily pain, disturbances to everyday activities and sleep, and problems with mood such as depression or anxiety.
- Trial name
- NCT05979337
- Testing
- Empowered Relief, Health Education (HE), Treatment as Usual
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Multiple Sclerosis, Spinal Cord Injury
Development of Pain Management JITAI Content in Multiple Sclerosis and Spinal Cord Injury
Just-In-Time Adaptive Interventions (JITAIs) offer a framework for delivering personalized behavioral support using time-varying data to optimize the timing and type of intervention content.
- Trial name
- NCT07663266
- Testing
- Push Notification Content
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Polycystic Ovary
The Supporting Understanding of PCOS Education and Research (SUPER) Study
This research will test whether a Dietary Approaches to Stop Hypertension (DASH) or a very low-carbohydrate diet better improves outcomes like blood glucose control and body weight for adults with polycystic ovary syndrome.
- Trial name
- SUPER (NCT05452642)
- Testing
- DASH diet, Very low-carbohydrate diet
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Michigan
Opioid Use
Prevention Interventions for Opioid Misuse
The purpose of the study is to develop and test innovative interventions to prevent the development of opioid misuse and opioid use disorders among older adolescents and young adults (AYA; ages 16-30) who use opioids, which will…
- Trial name
- NCT04550715
- Testing
- Brief intervention (BI), Portal, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 1,155 people
- Sponsor
- University of Michigan
Glucose Intolerance
Metabolic Adaptations in Response to High Intensity Interval Training in Obese Adults
The overall objectives are to: 1. Assess mechanisms underlying HIIT-induced improvements in insulin resistance at the whole-body, tissue, and cellular levels. 2.
- Trial name
- HT (NCT02706093)
- Testing
- High Intensity Interval Training (HIIT), Moderate-intensity continuous training (MICT)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Diabetes Mellitus, Glaucoma
Smartphone Screening for Eye Diseases
To validate new screening instruments for eye disease, increase eye care access in underserved communities, and provide a scientifically implemented method to set up programs for eye disease screening.
- Conditions
- Diabetes Mellitus, Glaucoma, Age Related Macular Degeneration, ROP
- Trial name
- NCT03076697
- Testing
- Fundus photography
- Volunteers
- 472 people
- Sponsor
- University of Michigan
Chronic Pain
STEPS: An Efficacy Trial of a Chronic Pain Self-Management Program for Older Adults
The goal of this study is to determine whether community health workers (CHWs)-i.e., lay health workers with close ties to the communities they serve - can effectively teach cognitive-behavioral pain management strategies to…
- Trial name
- NCT05278234
- Testing
- STEPS
- Where
- United States
- Volunteers
- 414 people
- Sponsor
- University of Michigan
Depressive Symptoms, Anxiety
A Trial of a Positive Psychology Intervention for Older Adults (RESET)
The heightened vulnerability to COVID-19 of African American older adults in Detroit, Michigan and other marginalized communities is linked to systemic racism experienced over the life course.
- Conditions
- Depressive Symptoms, Anxiety, Chronic Pain, Fatigue
- Trial name
- NCT05451589
- Testing
- RESET, Wellness Check Control
- Where
- United States
- Volunteers
- 457 people
- Sponsor
- University of Michigan
Suicide
Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska
This intervention study measures the outcomes of the PC CARES (Promoting Community Conversations about Research to End Suicide) project implemented in remote rural Alaskan villages.
- Trial name
- PC CARES (NCT03661255)
- Testing
- PC CARES
- Where
- United States
- Volunteers
- 1,427 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Breast Cancer, Colorectal Cancer
Michigan Genetic Hereditary Testing (MiGHT)
The primary purpose of this study is to compare three interventions, two experimental and one standard of care (usual care), to see if the experimental interventions will increase the likelihood of a participant obtaining…
- Conditions
- Breast Cancer, Colorectal Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- MiGHT (NCT05162846)
- Testing
- Publicly available genetic testing resources, Virtual genetics navigator, Motivational interviewing (MI)
- Where
- United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Mild Cognitive Impairment, Alzheimer Disease
Behavioral Change Following Alzheimer's Disease (AD) Biomarker Disclosure
The proposed project will assess long-term changes to health/lifestyle, advanced planning, and research engagement that Black and White patients with Amnestic Mild Cognitive Impairment (aMCI) make following disclosure of positron…
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Amnestic Mild Cognitive Disorder
- Trial name
- SHARED III (NCT05584241)
- Testing
- Diagnostic Disclosure Protocol, Biomarker Disclosure Protocol
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Michigan
Physical Inactivity
Tele-video to Improve Daily Activity
This pilot study will test the feasibility of pairing a social network-based approach with a 6-week Occupational Therapist (OT)-led intervention administered remotely (via Zoom) to increase physical function and activity among…
- Trial name
- T-VIDA (NCT06007664)
- Testing
- Tele-Video to Improve Daily Activity
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Michigan