Clinical trials: completed, sponsored by University of California, San Francisco
Cigarette Smoking
Mechanisms of the Nicotine Metabolism Effect on Tobacco Dependence
The purpose of the study is to learn more about tobacco dependence and nicotine metabolism in African-Americans and whites, by studying to see if how fast a person metabolizes nicotine (how the body breaks down nicotine into…
- Trial name
- NMR (NCT01627392)
- Testing
- Smoking abstinence
- Where
- United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Idiopathic Pulmonary Fibrosis
Microaspiration in Pulmonary Fibrosis
Hypothesis 1: Microaspiration, as diagnosed by bronchoalveolar lavage (BAL) pepsin, is common in patients with IPF. Hypothesis 2a: Baseline clinical variables and co-morbid conditions are risk factors for microaspiration in…
- Trial name
- ROMI (NCT01150591)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Malaria
Chemopreventive Therapy for Malaria in Ugandan Children
Young African children living in high transmission areas suffer the greatest burden of malaria. In most African countries, such as Uganda, the only current preventive measure against malaria in high transmission settings is the…
- Trial name
- PROMOTE-Chemop (NCT00948896)
- Testing
- trimethoprim-sulfamethoxazole (TS; TMP/SMX), sulfadoxine-pyrimethamine (SP), dihydroartemisinin-piperaquine (DP)
- Where
- Uganda
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Type 2 Diabetes
Examining the Effects of Diet on Health With an Online Program
The study is a pilot, designed to provide data regarding the feasibility and acceptability of conducting such a study on a larger scale.
- Trial name
- NCT01967992
- Testing
- Behavioral: Low Carbohydrate, Ketogenic Diet, American Diabetes Association Diet, Mindfulness and Positive Affect Skills
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Francisco
Prostate Cancer
Hyperpolarized Pyruvate Injection in Subjects With Prostate Cancer
Current imaging options do not assess prostate cancer well. This study will combine two magnetic resonance imaging modalities, MRI and MRSI, in order to determine the utility to physicians and patients with prostate cancer in…
- Trial name
- NCT01229618
- Testing
- Hyperpolarized Pyruvate (13C) injection
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, San Francisco
Attitudes
Pilot #2 of Social Network Intrauterine Contraceptive (IUC) Intervention
This study has two goals: 1) to test an approach to helping women who use intrauterine contraception (IUC) spread the word about this type of long-lasting, highly effective birth control method among their friends and family and…
- Trial name
- NCT02242890
- Testing
- Contraception Information Packet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Trachoma, Chlamydia
Trachoma Amelioration in Northern Amhara (TANA)
The WHO has initiated a program to eliminate trachoma, blinding eye infection caused by Chlamydia trachomatis, in large part by mass distributions of oral azithromycin.
- Trial name
- TANA (NCT00322972)
- Testing
- Mass treatment with oral azithromycin to an entire community
- Where
- Ethiopia
- Volunteers
- 33,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Brain and Central Nervous System Tumors, Lymphoma
Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Primary CNS Lymphoma
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00416819
- Testing
- filgrastim, rituximab, cytarabine
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
HIV Infections, Acquired Immunodeficiency Syndrome
Effectiveness of Structured Ecosystems Therapy for Reducing HIV Risk Behaviors and Improving Treatment Adherence in HIV Infected Men Released From Prison
This study will evaluate the effectiveness of Structured Ecosystems Therapy (SET), a form of therapy that includes family and caregivers, at reducing HIV transmission risk behaviors and improving treatment adherence in HIV…
- Trial name
- NCT00344591
- Testing
- Structured Ecosystems Therapy (SET), Individually tailored intervention
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- University of California, San Francisco
Trachoma, Chlamydia
Trachoma Elimination Follow-up
The WHO has initiated a program to eliminate blinding trachoma by the year 2020, in large part by mass oral azithromycin distributions. It is not clear how frequently or for how long these treatments are necessary.
- Trial name
- TEF (NCT00221364)
- Testing
- Mass treatment with oral azithromycin to an entire village
- Where
- Ethiopia
- Volunteers
- 20,000 people
- Sponsor
- University of California, San Francisco
Delirium, Sleep Disorders, Circadian Rhythm
Study of Sleep and Delirium in the Intensive Care Unit (ICU)
The investigators will perform a prospective, cohort study of 100 older intensive care unit (ICU) patients, to investigate the association between sleep disruption and ICU delirium.
- Trial name
- SID (NCT01280097)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Francisco
Migraine, Chronic Migraine
Neuroimaging Studies of Chronic Primary Headaches Using Positron Emission Tomography and Magnetic Resonance Imaging
Investigators hypothesize that chronic primary headaches are accompanied by a discrete pattern of brain metabolism and activity involving brain structures related to the development of acute exacerbations as well as pain…
- Trial name
- NCT01741246
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Endothelial Function, Rheumatoid Arthritis
Cardiovascular Risk Markers in Patients With Rheumatoid Arthritis: Effect of Rituximab Therapy
The purpose of this investigation is to determine the effects of Rituxan therapy in individuals with rheumatoid arthritis on endothelial function and other markers of endothelial function
- Conditions
- Endothelial Function, Rheumatoid Arthritis, Inflammation
- Trial name
- NCT00844714
- Testing
- Rituxan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Chronic Stable Plaque Psoriasis
Safety and Efficacy Study of Combination Treatment With Excimer Laser, Clobex Spray, and Vectical Ointment in the Treatment of Psoriasis
This is a 12-week, open-label, pilot trial evaluating the efficacy and safety of the combination of Clobex® spray with excimer laser therapy as the initial treatment of generalized plaque psoriasis, followed by maintenance…
- Trial name
- NCT01012713
- Testing
- Clobex Spray, Vectical Ointment, Excimer Laser
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Myocardial Infarction, Chest Pain
Tele-Electrocardiography in Emergency Cardiac Care
The purpose of this study is to see whether individuals who access the "911" emergency medical system with a heart attack or severe chest pain will receive more timely hospital treatment and better outcomes if hospital clinicians…
- Trial name
- NCT00075088
- Testing
- Electrocardiogram (ECG) Intervention, Routine Clinical Practice
- Where
- United States
- Volunteers
- 794 people
- Sponsor
- University of California, San Francisco
HIV
The Navigator Project
Each year, there are over 600 unduplicated HIV-infected persons incarcerated in the San Francisco jail. Two thirds of those released with HIV-focused discharge planning are reincarcerated within one year.
- Trial name
- NAV (NCT02106702)
- Testing
- Navigator enhanced case-management, Forensic AIDS Project
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- University of California, San Francisco
Patients Undergoing Spine Surgery
Assessing the Accuracy of the RevK Sensor
Evaluation of a new generation of sensors for monitoring blood hemoglobin. The newest version is RevK.
- Trial name
- NCT01877876
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Depression, Substance-Related Disorders
Motivational Interviewing to Reduce Substance Use Among Depression Patients
The study aims to evaluate the effectiveness of an intervention to reduce alcohol and drug use and depression symptoms, improve functional status and promote appropriate health services utilization, in a sample of 300 adults…
- Trial name
- NCT02420561
- Testing
- Motivational Interviewing, Control (brochure)
- Where
- United States
- Volunteers
- 307 people
- Sponsor
- University of California, San Francisco
Surgical Procedure, Unspecified
Development and Pilot Test of an Elective Bilateral Salpingo-Oophorectomy (BSO) Decision Support Guide
The investigators propose to conduct formative research to gain an understanding of patients' needs and desires regarding elective Bilateral Salpingo-Oophorectomy (BSO) decision making, and to develop and pilot test a BSO…
- Trial name
- BSO (NCT01369654)
- Testing
- Computerized decision aid with 1 type of value clarification
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dementia
Preventing Loss of Independence Through Exercise (PLIÉ) - Pilot
The primary goal of this study is to perform a 36-week pilot study with a cross-over design to study the safety and efficacy of a novel integrative exercise program called PLIÉ (Preventing Loss of Independence through Exercise).
- Trial name
- PLIÉ-pilot (NCT01371214)
- Testing
- PLIÉ (Preventing Loss of Independence through Exercise)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
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