Clinical trials: sponsored by Cairo University
Anterior Cruciate Ligament Tear, Ankle Sprains
Effect of ACL Reconstruction in Biomechanical Properties of Ankle Joint Complex
BACKGROUND: Anterior cruciate ligament (ACL) is an important ligamentous structure in the knee joint which contributes in maintaining stability.
- Trial name
- NCT06631690
- Testing
- Isokinetic and functional balance tests
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Vital Pulp Therapy
Age-Related Inflammatory Proteins as Indicators of Vital Pulp Therapy Outcomes
Predicting the success of vital pulp therapy remains a clinical challenge. There is a knowledge gap regarding the relationship between age, inflammasome related proteins expression , and clinical/radiographic outcomes.
- Trial name
- NCT07893977
- Testing
- Standardized complete pulpotomy protocol
- Volunteers
- 75 people
- Sponsor
- Cairo University
General Anesthesia; Tracheal Intubation
Association of WWI With Difficult Intubation
Difficult intubation remains a clinically significant challenge in anesthetic practice, particularly among patients with obesity and altered body composition.
- Trial name
- WWI (NCT07894692)
- Testing
- Weight, Height, BMI, Waist circumference, WWI, Neck circumference, Mallampati score, Sternomental distance, EGRI score, BMV grade Cormack-Lehane grade,Number of attempts Use of adjunts
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Neck Pain Musculoskeletal
Effect of Body Mind Exercises and Specific Neck Exercises in Chronic Mechanical Neck Pain
To investigate the effect of body mind exercise and specific neck exercises in chronic mechanical neck pain on neck pain severity, functional disability, neck flexion range of motion, isometric neck muscle strength and quality of…
- Trial name
- BME-SNE (NCT07477145)
- Testing
- Conventional physical therapy group., Body mind exercises group (mindful aerobic exercises), specific neck exercise group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Forward Head Posture
Relationship of Forward Head Posture With Burnout and Quality of Life
The goal of this observational study is to investigate the relationship of forward head posture with burnout and quality of life in patients with mechanical neck pain.
- Trial name
- NCT07891260
- Testing
- postural, physical, and cognitive assessment
- Volunteers
- 50 people
- Sponsor
- Cairo University
Psoriasis, Psoriasis Genital
Efficacy of Crisaborole 2% Ointment Versus Tacrolimus 0.1% Ointment in the Treatment of Intertriginous and/or Anogenital Psoriasis: A Prospective Randomized Controlled Study.
The goal of this clinical trial is to learn if topical application of crisaborole 2% ointment can treat flexural and/or genital psoriasis in adult patients of both genders.
- Trial name
- NCT07892339
- Testing
- Crisaborole 2% topical ointment, tacrolimus ointment 0.1%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Acute Myocardial Infarction, Dyslipidemias
Ezetimibe Utilization Early After Acute Myocardial Infarction, "EzAMI Trial"
Rationale: Patients with acute coronary syndromes are at an increased risk for recurrent adverse coronary events, particularly during the early period following their initial presentation.
- Trial name
- EzAMI (NCT04701242)
- Testing
- Ezetimibe 10mg
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Insulin Sensitivity/Resistance
Aerobic Versus Resistance Exercises on Insulin Sensitivity in Obese Patients
The purpose of study is to compare the effect of different exercise modes on insulin resistance and body composition in obese patients.
- Trial name
- NCT06772857
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Emergency Abdominal Surgery, Opioid Sparing Anaesthesia
Effect of Opioid-sparing Anesthesia on Quality of Recovery After Emergency Laparotomy
Opioids are widely used during anesthesia for pain control, but they cause many side effects-such as nausea, constipation, respiratory depression, dependence, and delayed recovery.
- Trial name
- NCT07262242
- Testing
- Lidocaine (drug), Fentanyl (IV)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Benign Prostate Enlargement
Electromagnetic Field Therapy Versus Aerobic Exercise on Prostatic Function in Elderly With Benign Prostatic Hyperplasia
This study will be carried out on seventy five elderly patients with benign prostatic hyperplasia. Their age will range from 60 to 75 years old.
- Trial name
- NCT07357168
- Testing
- pulsed electromagnetic field, Treadmill machine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Lower-Limb Lipedema, Lipedema
"Effect of Endermologie-Assisted Physiotherapy on Edema, Pain, and Functional Recovery After Liposuction for Lower-Limb Lipedema"
Lipedema is a chronic condition that mainly affects women and causes abnormal fat accumulation, pain, heaviness, tenderness, swelling, and difficulty with movement, especially in the lower limbs.
- Trial name
- NCT07618065
- Testing
- Endermologie-Assisted Physiotherapy, Standard Postoperative Physiotherapy
- Where
- 2 sites in Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Gingival Hyperpigmentation, Oral Health-Related Quality of Life
MEBO Bio-Dressing on Patient-Reported Outcomes and Tissue Healing Following Rotary Gingival Depigmentation
The purpose of this randomized, single-blind, parallel-group clinical trial is to evaluate the clinical efficacy of Moist Exposed Burn Ointment (MEBO) as a biological topical dressing compared to open secondary healing (no…
- Conditions
- Gingival Hyperpigmentation, Oral Health-Related Quality of Life, Wound Healing
- Trial name
- NCT07876921
- Testing
- MEBO Ointment
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Guillain-Barre Syndrome
Ventilator Trigger Sensitivity Adjustment Versus Threshold Inspiratory Muscle Training on Arterial Blood Gases
The aim of the current study is to compare the effect of ventilator trigger sensitivity adjustment versus threshold inspiratory muscle training on arterial blood gases in mechanically ventilated patients.
- Trial name
- NCT06167239
- Testing
- Threshold inspiratory muscle trainer or ventilator pressure setting inspiratory muscle training techniques
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Mutilated Teeth, Endodontically Treated Teeth
Shade Matching and Patient Satisfaction of Yttria Stabilized Multilayered Zirconia and Lithium Disilicate Restorations
The aim of the study is to determine whether Yttria stabilized multilayered zirconia restorations will differ from lithium disilicate restorations in shade matching and patient satisfaction in patients requiring full coverage…
- Trial name
- NCT06539546
- Testing
- Yttria stabilized multilayered (YML) zirconia restorations, Lithium disilicate restorations
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Bone Loss, Alveolar
Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts
In patients with a single non restorable tooth, does filling the peri-implant buccal gap with alloplastic sticky grafts result comparable results compared to xenogenic sticky grafts?
- Trial name
- NCT06653868
- Testing
- Immediate dental implant with filling the peri implant gap with xenogenic sticky bone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients
The study aims to evaluate the effects of combination of metformin with NAC in PCOS on biochemical and hormonal parameters.
- Trial name
- PCOS (NCT06836128)
- Testing
- N-acetyl cysteine, Metfomin
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Cairo University
Swimmer Shoulder
Combined Effect of Biofeedback and Scapular Stabilization Exercises in Children With Swimmer's Shoulder
The purpose of this study is to investigate the combined effect of biofeedback and scapular stabilization exercises on swimmer's shoulder in pediatric elite swimmers.
- Trial name
- NCT07067216
- Testing
- Designed scapular stabilization using pressure biofeedback, Designed physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Teeth Staining, Numbness of the Tongue and Soft Tissue
Children Acceptance of AgNP Mouthwash Against Chlorhexidine 0.12% and Chlorhexidine .2% Mouthwashs
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine 0.12% \& Chlorhexidine 0.2%
- Conditions
- Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste
- Trial name
- NCT07200063
- Testing
- nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Back Pain, Spondylolisthesis
Evaluation of Balance Using the Biodex Balance System Among Different Subcategories of Low Back Pain
this study aims to evaluate balance using the biodex balance system among patients with spondylosis, spondylolisthesis, and lumber disc prolapse.
- Conditions
- Low Back Pain, Spondylolisthesis, Spondylosis Lumbar, Balance Assessment
- Trial name
- Biodex (NCT07242976)
- Testing
- Assessment of balance will be measured by The Biodex Balance System (BBS) which computes Postural Stability key indices: the medial-lateral stability index (MLSI), anterior-posterior stability index
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Incidence of Post-spinal Hypotension
Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean Delivery
We hypothesize that the addition of ephedrine to norepinephrine infusion could decrease the incidence of post spinal hypotension(PSH) in parturient undergoing C.S under spinal anesthesia and minimize the changes in heart rate
- Trial name
- NCT07379710
- Testing
- Ephedrine and Norepinephrine infusion, Norepinephrine infusion
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Cairo University