Clinical trials: Treatment as usual
Stress Disorders, Post-Traumatic
Intensive Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)
This study is investigating the efficacy of an intensive (3 week) integrated treatment for Veterans with both pain and PTSD.
- Trial name
- NCT01120067
- Testing
- Intensive Treatment, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- VA Office of Research and Development
Stroke
Very Early Rehabilitation in Acute Ischemic Stroke
The purpose of this study is to evaluate the effectiveness of a rehabilitation (physiotherapy) program in patients with acute ischemic stroke in Acute Vascular Unit and in general ward of Hospital de Clínicas de Porto Alegre, and…
- Trial name
- VERIS-Brazil (NCT01694992)
- Testing
- Early mobilization
- Where
- Brazil
- Volunteers
- 184 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Opioid Abuse, Prescription Opioid Abuse
Community Pharmacy-Based Prescription Drug Monitoring Program Opioid Risk Assessment Tool
This goal of this observational study is to develop and test the Opioid Risk Reduction Clinical Decision Support (ORRCDS) tool. The tool will be an opioid medication risk screener and decision support platform that will be used…
- Trial name
- PharmTool (NCT05706311)
- Testing
- Clinical Decision Support Tool (Moderate Risk), Clinical Decision Support Tool (High Risk), Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Utah
Undiagnosed HIV Infection, Populations That Are Reluctant to Test for HIV
Expanded Social Network Recruitment to HIV Testing (E-SNRHT) Intervention to Locate Undiagnosed Cases and Reduce HIV-related Stigma
In South Africa's large generalized HIV epidemic, male-to-female transmission comprises a large proportion of transmission events, but men are much less likely to seek HIV testing, and disproportionately remain undiagnosed.
- Conditions
- Undiagnosed HIV Infection, Populations That Are Reluctant to Test for HIV, Long-term Undiagnosed HIV Infection, Individuals With Newly-diagnosed HIV Infection
- Trial name
- E-SNRHT (NCT06857071)
- Testing
- Expanded Social Network Recruitment to HIV Testing (E-SNRHT) Intervention
- Where
- South Africa
- Volunteers
- 2,480 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Depression, Non-psychotic Diagnosis as Co-morbidity
The Canadian Armed Forces PEER Study
This is a prospective, single-blinded, randomized, multicenter study to evaluate the utility, safety, and efficacy of using PEER Interactive - an EEG-based technology - to inform the prescription of medications to participants…
- Trial name
- PEERCanada (NCT03625271)
- Testing
- The PEER Report
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- MYnd Analytics
Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction
Bipolar Resection vs Enucleation of Prostate
The aim of this study is to evaluate efficacy and safety of transurethral resection of the prostate and bipolar enucleation of the prostate.
- Conditions
- Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction, Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
- Trial name
- TURP vs BiTUEP (NCT06983444)
- Testing
- TURP, TUEP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Valley University
Depression
Designing and Testing a Family Therapy for Adolescent Depression
This study will design and test a cognitive behavioral therapy for depressed adolescents that uses family interactions to help with treatment.
- Trial name
- NCT00867919
- Testing
- Behavioral Family Treatment, Community-based treatment as usual
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Oregon Research Institute
Preterm Birth Complication, Preterm Birth
Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities
The goal of this clinical trial is to learn if a personalized prenatal support program [(Personalized Toolkit Building a Comprehensive Approach to Resource optimization and Empowerment in Pregnancy \& Beyond, (PTBCARE+)] works to…
- Conditions
- Preterm Birth Complication, Preterm Birth, Preterm Birth Recurrence, Preeclampsia
- Trial name
- PTBCARE+ (NCT06915428)
- Testing
- Care coordination, Electronic massage, support gift #1
- Where
- United States
- Volunteers
- 1,228 people
- Sponsor
- University of North Carolina, Chapel Hill
Smoking Cessation
Neuroimaging Studies of Smoking and Treatment
The purpose of this research study is to examine changes in brain regions associated with cognitive control and reward processing during behavioral smoking cessation treatment.
- Trial name
- NCT03085602
- Testing
- Cognitive behavioral therapy, Health education
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Parenting Sensitivity, Foster Care
Enhancing Foster Care Relationships Through Attachment-Based Intervention: Protocol of SAFE FAMILY STUDY
Background: Children in out-of-home care constitute a vulnerable population often experiencing mental health challenges related to early adversity and placement disruptions.
- Trial name
- SAFE FAMILIES (NCT06701877)
- Testing
- Circle of security Parenting (COS-P), Traitement as usual (TAU)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Shankland Rebecca
Stroke, Upper Extremity Hemiplegia
"Remind-to-move" for Promoting Upper Extremity Recovery in Patients With Stroke After Subacute Discharge
This is a multi-centered randomized controlled trial to investigate the effects of "Remind-to-Move" (RTM) using wearable devices at home for promoting upper extremity recovery in stroke patients after discharge from subacute…
- Trial name
- NCT02952677
- Testing
- Remind-to-move, Control
- Volunteers
- 84 people
- Sponsor
- The Hong Kong Polytechnic University
Older People
Reablement in Residential Aged Care - a Randomized Controlled Trail
Background: The global increase in older adults presents challenges for maintaining health and autonomy in residential aged care (RAC) facilities, where passivity has been shown to often diminish quality of life.
- Trial name
- Re-RAC (NCT06793501)
- Testing
- Reablement intervention, Control group
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Region Örebro County
Hot Flashes, Prostate Cancer
Acupuncture Versus Sham Acupuncture or Usual Care for Antiandrogen-Induced Hot fLashes in Prostate Cancer (AVAIL)
Hot flashes are a common and debilitating symptom among prostate cancer patients undergoing androgen deprivation therapy (ADT). Strong evidence from multiple rigorously designed studies indicated that venlafaxine provides partial…
- Conditions
- Hot Flashes, Prostate Cancer, Acupuncture
- Trial name
- AVAIL (NCT05069467)
- Testing
- Acupuncture
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Opiate Addiction
Treatment Study Using Depot Naltrexone (1/6) Philadelphia Coord/Data Mgmt Site
The aim of this project is to conduct a multi-site effectiveness study to determine whether the addition of a monthly injection of depot naltrexone to treatment as usual (TAU) will significantly improve outcome in parolees and…
- Trial name
- NCT00781898
- Testing
- Depot naltrexone, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Venous Congestion, Heart Failure Acute
Vexus Assessment and Natriuresis-guided Diuretic Therapy in Acute Heart Failure
This study evaluates whether natriuresis-guided diuretic therapy improves outcomes in patients with acute heart failure (AHF) and severe congestion.
- Conditions
- Venous Congestion, Heart Failure Acute, VExUS, Diuretics
- Trial name
- VANTAGE-HF (NCT07558798)
- Testing
- Natriuresis-guided escalation of loop diuretics
- Where
- 2 sites in Norway
- Volunteers
- 270 people
- Sponsor
- University Hospital, Akershus
Eczema, Skin Conditions
A Randomised Clinical Trial on the Effect of Group Education on Patients With Occupational Hand Eczema
Occupational hand eczema (OHE) is a frequent disease which often takes a chronic course. The burden of the disease is high in a personal as well as in a socio-economic context.
- Trial name
- PREVEX (NCT01899287)
- Testing
- group education
- Where
- Denmark
- Volunteers
- 770 people
- Sponsor
- University of Copenhagen
Phobia Animal
Augmented Reality Exposure Therapy for Cynophobia
The feasibility study for the Augmented Reality Exposure Therapy for Cynophobia will be carried out for people with dog phobia. This feasibility study's sample will be adults living in Turkey.
- Trial name
- NCT05333783
- Testing
- Augmented Reality Exposure Therapy Based on ExposXR software
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Koç University
Major Depressive Disorder, Treatment Resistant Depression
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Over 28 million people suffer from current depressive disorder in the European Union. Major depressive disorder (MDD) is one of the most common psychiatric illnesses.
- Trial name
- INTENSIFY MDD (NCT05973851)
- Testing
- Esketamine Nasal Product, Ketamine Hydrochloride, Esketamine hydrochloride
- Where
- 12 sites in Austria, Germany and 4 more
- Volunteers
- 418 people
- Sponsor
- Dr. Inge Winter
Mental Health Impairment
Effectiveness of Tracking Goals in Counselling
Recent evidence suggests that focusing on positive goals rather than problems to avoid, may be associated with better psychological health and attainment of goals.
- Trial name
- Goals in MIND (NCT03000153)
- Testing
- Completing the Goals Form
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Pregnancy, Anxiety
Childbirth Education Pilot Study
This study aims to investigate the effects of mindfulness training on prenatal maternal anxiety using a randomized controlled trial (RCT).
- Trial name
- NCT04327557
- Testing
- MBCP Childbirth Education Course, Non-MBCP Childbirth Education Course
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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