Clinical trials: Ropivacaine, open to volunteers
Acute Pain, Opioid Use
CPB for Arthroscopic Hip Surgery
Arthroscopic hip surgery is being increasingly performed to treat both intraarticular and extraarticular hip diseases. Despite the minimally invasive approach, patients undergoing arthroscopic hip surgery still suffer severe pain…
- Trial name
- NCT06337968
- Testing
- Circum-psoas Block
- Volunteers
- 74 people
- Sponsor
- The Second Hospital of Shandong University
Pain, Postoperative Children
Pre-emptive Scalp Infiltration with Triamcinolone Acetonide Plus Ropivacaine for Post-Craniotomy Pain in Children
At present, pediatric postoperative analgesia has not been fully understood and controlled, particularly craniotomy surgery. On the one hand, professional evaluation of postoperative pain for young children is difficult; on the…
- Trial name
- NCT06779396
- Testing
- The triamcinolone acetonide plus ropivacaine group, The ropivacaine group
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Beijing Tiantan Hospital
Total Hip Arthroplasty (THA)
Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty
The Erector Spinae Plane (ESP) block or spinal erector block was first described in September 2016 by a Canadian team. It's a block that was initially used for the treatment of chronic thoracic neuropathic pain.
- Trial name
- NCT07240961
- Testing
- Lumbal Erector Spinae Plane Block, intravenous pain killers
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Autonomic Nerve Block
Sternotomy PIFB Block in Open Heart Surgery
The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia [MMA]), has a favorable effect…
- Trial name
- NCT06233318
- Testing
- Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine, Pecto-intercostal Fascial Block with normal saline
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Ohio State University
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
This Study Evaluates the Effects of Different Fascial Plane Blocks on Intraoperative Anesthesia and Analgesic Consumption in Non-intubated VATS Procedures
Comparison of SPSIP Block and SAP Block in Non-Intubated Uniportal VATS.
Comparison of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block in Uniportal Video-Assisted Thoracoscopic Surgery Without Intubation Single-port video-assisted thoracoscopic surgery without…
- Trial name
- NCT07440199
- Testing
- Serratus Anterior Plane Block (SAPB) group, Serratus posterior superior intercostal plane block group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Firat University
Spine Disease
Lumbar Paravertebral Block vs Erector Spinae Plane Block in Elderly Patients Undergoing Lumbar Spine Surgery
This prospective, randomized controlled trial aims to compare the analgesic efficacy of lumbar paravertebral block (L-PVB) and lumbar erector spinae plane block (L-ESPB) in elderly patients undergoing lumbar spine surgery.
- Trial name
- NCT07607509
- Testing
- Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Hip, Hip Osteoarthritis
Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty
his study will test whether giving dexamethasone through a vein can improve pain control after total hip replacement surgery. Dexamethasone is commonly used to reduce nausea and may also help with pain, but it is not clear which…
- Trial name
- NCT07581470
- Testing
- Dexamethasone 4mg, Dexamethasone 8mg
- Where
- Poland
- Volunteers
- 198 people
- Sponsor
- Poznan University of Medical Sciences
Gender Affirming Surgery, Mastectomy
Gender Affirming Mastectomy Analgesia Rial
Introduction: Optimizing pain management after gender-affirming mastectomy (removal of breast tissue, aka top surgery) surgery is important for recovery and minimizing opioid use.
- Conditions
- Gender Affirming Surgery, Mastectomy, Acute Pain
- Trial name
- GAMA (NCT07861165)
- Testing
- Paravertebral (single injection), Wide local infiltration
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Nova Scotia Health Authority
ENT Cancers
Evaluation of the Superficial Cervical Plexus Block in Oncological Throat and Neck Surgery
This national, prospective, multicenter, randomized study aims to reduce the amount of intravenous morphine (titration + PCA morphine) during the first 24 postoperative hours via a locoregional anesthesia technique in patients…
- Trial name
- BCS-ORL (NCT07110857)
- Testing
- Cervical plexus block with 0.2 % Naropeine
- Where
- 7 sites in France
- Volunteers
- 346 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lumbar Spinal Stenosis, Lumbar Radiculopathy
Continuous Erector Spinae Block for Analgesia Following Lumbar Decompression
Lumbar spinal surgery is common, and the incidence of spinal fusion has increased dramatically over the past three decades. Patients requiring spinal surgery are typically prescribed several analgesics, (including opioids) while…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Radiculopathy, Persistent Postsurgical Pain
- Trial name
- Lumbar-ESP (NCT06987409)
- Testing
- Continuous erector spinae plane block
- Volunteers
- 100 people
- Sponsor
- Nova Scotia Health Authority
Pain, Postoperative
Quadratus Lumborum Block for Total Hip Arthroplasty
The quadratus lumborum (QL) block is a fascial plane block that has been described to provide analgesia from T7-L3 dermatomes. The investigators aim to evaluate the efficacy of QL blocks in patients undergoing primary total hip…
- Trial name
- NCT05247255
- Testing
- Active Comparator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Postoperative Care, Analgesia Assessment
Posthectomy in Pediatric Elective Surgery : a Comparison of Perioperative Analgesia Using Echo-guided Penile Block and Pudendal Block With neurostimuLation Technique
Context : Posthectomy is a surgical procedure that concerns around 30% of the male population, mainly in pediatrics. As this procedure is mainly performed on an outpatient basis, the implementation of an enhanced rehabilitation…
- Conditions
- Postoperative Care, Analgesia Assessment, Posthectomy, Postoperative Analgesia
- Trial name
- PinEAPPLE (NCT07191938)
- Testing
- Ultrasound guided penile block, Neurostimulation guided pudendal block
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Caen
Postoperative Pain, Postoperative Acute Pain
Comparative Analysis of the Impact of Transversus Abdominis Plane Block on Post-Cesarean Pain Management Using Low Concentration Ropivacaine 0,2%
The goal of this clinical trial is to evaluate whether the addition of a Transversus Abdominis Plane (TAP) block improves postoperative outcomes in women undergoing cesarean section.
- Trial name
- NCT07604376
- Testing
- Postoperative analgesia using TAP block, Ropivacaine 0,2%, volume: 0,4 ml/kg per side, Postoperative pain management using "traditional" analgesia iv regime
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Matild Keresztes
Postoperative Pain, Thoracic Surgery
Ultrasound-Guided Rhomboid-Intercostal Block Versus Thoracic Paravertebral Block for VATS Analgesia
Purpose of the study The goal of this research is to see which of two nerve-numbing techniques-the Rhomboid-Intercostal Block (RIB) or the Thoracic Paravertebral Block (PVB)-works better to control pain after chest surgery…
- Conditions
- Postoperative Pain, Thoracic Surgery, Thoracic Surgery, Video Assisted, Ultrasound Guided
- Trial name
- NCT07465887
- Testing
- Ultrasound-Guided Rhomboid-Intercostal Block (RIB), Ultrasound-Guided Thoracic Paravertebral Block (PVB)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Georgios Kotsovolis
Hallux Valgus, Anesthesia
The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks
Peripheral nerve blocks are essential in ensuring effective regional anesthesia and postoperative analgesia in forefoot surgery for hallux valgus repair, with or without minor concomitant toe procedures.
- Trial name
- ROADS (NCT06185608)
- Testing
- 0.25% ropivacaine, 0.5% ropivacaine, 1% ropivacaine
- Where
- Belgium
- Volunteers
- 174 people
- Sponsor
- Ziekenhuis Oost-Limburg
Sickle Cell, Sickle Cell Disease
Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients
Sickle cell disease is a chronic disease characterized by multiple vaso-occlusive complications. The basic treatment for patients with a vaso-occlusive crisis (VOC) is based on adequate hydration, oxygen therapy and pain control.
- Conditions
- Sickle Cell, Sickle Cell Disease, Vaso-Occlusive Crises
- Trial name
- ALRCVO-MP (NCT07001189)
- Where
- Guadeloupe
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Osteoarthritis (OA) of the Knee, Total Knee Arthroplasty
GENicular Nerve Block in KNEE Arthroplasty
The goal of this clinical trial is to learn whether a preoperative genicular nerve block (GNB) can reduce pain after knee replacement surgery in adults with knee osteoarthritis (OA) undergoing total knee arthroplasty (TKA).
- Conditions
- Osteoarthritis (OA) of the Knee, Total Knee Arthroplasty, Genicular Nerve Block
- Trial name
- GENKNEE (NCT07589127)
- Testing
- Preoperative genicular nerve block (GNB)
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Helse Møre og Romsdal HF
Resting Visual Analog Scale (VAS) Pain Score
Liposomal Bupivacaine vs Ropivacaine for Post-hemorrhoidectomy Analgesia
This is a single-center, prospective, randomized, double-blind controlled trial comparing the analgesic efficacy, quality of recovery, and safety of perianal wound infiltration with multivesicular liposomal bupivacaine (266 mg)…
- Trial name
- NCT07795203
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine, Ropivacaine Hydrochloride
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Tongliao City People's Hospital
Stellate Ganglion Block, Prolonged Disorders of Consciousness
Stellate Ganglion Block on Postoperative Sleep Status in Patients With Prolonged Disorders of Consciousness
This is a prospective, single-centre, single-arm, self-controlled, exploratory pilot study. The goal of this clinical trial is to learn about the effect of preoperative administration of stellate ganglion block on postoperative…
- Conditions
- Stellate Ganglion Block, Prolonged Disorders of Consciousness, Sleep
- Trial name
- NCT07274683
- Testing
- stellate ganglion block with 0.5% ropivacaine
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Beijing Tiantan Hospital