Clinical trials: Pregabalin
Epilepsies, Partial
Efficacy And Safety Study Of Pregabalin (Lyrica) As Monotherapy In Patients With Partial Seizures
This study will determine the safety and efficacy of pregabalin (Lyrica) when administered by itself (without any other anti-epileptic medication) to epilepsy subjects for the treatment of partial seizures.
- Trial name
- NCT00524030
- Testing
- pregabalin 600 mg/day, pregabalin 150 mg/day
- Where
- 73 sites in United States, Czechia and 2 more
- Volunteers
- 161 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuropathy, Pain
Pregabalin in CIPN
The investigators seek to investigate certain patient characteristics that would predict the response to a currently approved analgesic, pregabalin, in patients with chronic pain due to nerve damage caused by chemotherapy.
- Trial name
- NCT02394951
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Washington University School of Medicine
Partial Seizures, Epilepsies, Partial
Once-A-Day Pregabalin For Partial Seizures
Approximately 30% percent of subjects with partial seizures are refractory to treatment with single or combination antiepileptic drugs.
- Trial name
- NCT01262677
- Testing
- pregabalin
- Where
- 82 sites in United States, Argentina and 16 more
- Volunteers
- 325 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain, Peripheral Neuropathy
Pregabalin in Preventing Acute Pain Syndrome in Patients Receiving Paclitaxel
This randomized pilot clinical trial studies pregabalin in preventing acute pain syndrome in patients receiving paclitaxel. Pregabalin may control the pain caused by cancer treatment.
- Trial name
- NCT01637077
- Testing
- pregabalin, questionnaire administration
- Where
- 6 sites in United States
- Volunteers
- 46 people
- Sponsor
- Academic and Community Cancer Research United
Gulf War Illness
Research Examining Gulf War Illness in Our Nations Service Members
At least 1 in 4 of the 700,000 U.S. Veterans who served in the 1990-1991 Gulf War suffer from Gulf War Illness (GWI). Despite considerable research, effective treatments remain elusive.
- Trial name
- REGIONS (NCT01846182)
- Testing
- Duloxetine, Pregabalin
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- VA Office of Research and Development
Fibromyalgia, Sleep Disorders
Effects Of Pregabalin (Lyrica) On Sleep Maintenance In Subjects With Fibromyalgia
The purpose of the study is to demonstrate the effect of Lyrica on Wake after sleep onset in subjects with fibromyalgia with sleep maintenance disturbance (on polysomnogram)
- Trial name
- NCT00883740
- Testing
- Pregabalin
- Where
- 50 sites in United States, Canada and 1 more
- Volunteers
- 119 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Diabetic Peripheral Neuropathic Pain
A Study of Duloxetine (LY248686) in Participants With Diabetic Peripheral Neuropathic Pain (DPNP)
The main purpose of this study is to evaluate the effectiveness and safety of the study drug known as duloxetine in participants with diabetic peripheral neuropathic pain.
- Trial name
- NCT02417935
- Testing
- Duloxetine, Pregabalin
- Volunteers
- 304 people
- Sponsor
- Eli Lilly and Company
Idiopathic Small Fiber Neuropathy
Efficacy and Safety of Pregabalin in Treatment of Neuropathic Pain in Patients With Idiopathic Small Fiber Neuropathy
The purpose of this study is to assess safety and efficacy of treatment with pregabalin in patients with idiopathic small fiber neuropathy proven by skin biopsy.This is an enriched enrollment randomized withdrawal study that…
- Trial name
- NCT02607254
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Johns Hopkins University
Neuralgia, Postherpetic
A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Postherpetic Neuralgia
To evaluate the safety of the long-term use of pregabalin.
- Trial name
- NCT00424372
- Testing
- pregabalin
- Where
- 33 sites in Japan
- Volunteers
- 126 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Primary Total Knee Arthroplasty
Effects of Pregabalin on Pain After Total Knee Arthroplasty
Total knee arthroplasty can cause severe postoperative pain, and patients typically receive oral opioid analgesics for over 2 weeks.
- Trial name
- NCT01333956
- Testing
- Pregabalin 50mg, Pregabalin 100mg, Pregabalin 150mg
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Hospital for Special Surgery, New York
Cryptogenic Sensory Polyneuropathy
Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations
The purpose of this large comparative effectiveness study led by Richard J. Barohn, MD, of the University of Kansas Medical Center, is to learn about the safety and effectiveness of nortriptyline, duloxetine, pregabalin and…
- Trial name
- PAIN-CONTRoLS (NCT02260388)
- Testing
- Nortriptyline, Duloxetine, Pregabalin
- Where
- 46 sites in United States, Canada
- Volunteers
- 402 people
- Sponsor
- University of Kansas Medical Center
Epilepsy
Non-Interventional Study With LYRICA (Pregabalin) In Patients With Epilepsy As Adjunctive Therapy Of Partial Seizures To Reduce Seizure Frequency
The primary efficacy parameter will be the responder rate, defined as the proportion of subjects who had at least a 50% reduction in 28 day seizure rate during the maintenance phase
- Trial name
- NCT00684424
- Testing
- Non-Interventional Study
- Volunteers
- 199 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain, Postoperative, Hernia, Inguinal
Surgical Pain After Inguinal Hernia Repair (SPAIHR)
The purpose of this study is to test whether pregabalin added to the standard of care with dosing starting preoperatively and continuing for 1 week post surgery will decrease the intensity of acute post-operative pain following…
- Trial name
- NCT00551135
- Testing
- Pregabalin
- Where
- 42 sites in United States, Australia and 4 more
- Volunteers
- 425 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain, Postoperative
Study Evaluating the Effects of Toradol and Lyrica for Pain Control After Donor Nephrectomy
The investigators will assess how the use of toradol and pregabalin affects return to bowel function and see if there is a difference in length of hospital stay.
- Trial name
- NCT03669081
- Testing
- Ketorolac, Pregabalin, Saline
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Utah
Peripheral Neuropathic Pain
NEP-TUNE: Neuropathic Pain - Treatment With Pregabalin Under Real-life Conditions in Denmark
Observational study to assess the effectiveness and use of pregabalin (Lyrica) in the treatment of patients with peripheral neuropathic pain in real-life daily clinical practice.
- Trial name
- NEP-TUNE (NCT01524796)
- Testing
- No intervention. Non-interventional study
- Volunteers
- 128 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Post Herpetic Neuralgia
Safety And Efficacy Study Of Once Daily Controlled Release Pregabalin In The Treatment Of Patients With Postherpetic Neuralgia
The purpose of the study is to explore the safety and efficacy of a new once a day pregabalin formulation versus placebo for patients with post herpetic neuralgia (Shingles)
- Trial name
- NCT01270828
- Testing
- Pregabalin
- Where
- 146 sites in United States, Bulgaria and 15 more
- Volunteers
- 806 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Nephrolithiasis, Urolithiasis
Perioperative Pregabalin in Ureteroscopy: a Pilot
The investigators propose a pilot clinical trial on the use of perioperative pregabalin in order to decrease ureteral stent related symptoms and decrease opioid usage after ureteroscopy with stent placement.
- Conditions
- Nephrolithiasis, Urolithiasis, Perioperative/Postoperative Complications, Pain, Postoperative
- Trial name
- NCT03927781
- Testing
- Pregabalin 300mg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
HIV-1 Infection, Neuropathic Pain
Pregabalin Trial In HIV Neuropathic Pain
This study examines the safety of pregabalin over a 6 month period in patients with neuropathic pain associated with HIV infection as an extension of another trial that tests the efficacy of pregabalin.
- Trial name
- NCT01145417
- Testing
- pregabalin (Lyrica)
- Where
- 29 sites in United States, Colombia and 5 more
- Volunteers
- 217 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
The purpose of this study is to determine whether pregabalin is an effective treatment for Chronic Prostatitis/Chronic Pelvic Pain Syndrome.
- Trial name
- CPCRN RCT#2 (NCT00371033)
- Testing
- Pregabalin
- Where
- 11 sites in United States, Canada
- Volunteers
- 324 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Anxiety Disorders
PharmacofMRI of Anxiolytic Medications (Pregabalin)
The purpose of this study is to use functional magnetic resonance imaging (fMRI) in healthy controls to examine the acute effects of certain anxiolytic medications on brain function.
- Trial name
- NCT00706836
- Testing
- Pregabalin 50mg, Pregabalin 200 MG
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego