Clinical trials: Pregabalin
Epilepsies, Partial
Efficacy And Safety Study Of Pregabalin (Lyrica) As Monotherapy In Patients With Partial Seizures
This study will determine the safety and efficacy of pregabalin (Lyrica) when administered by itself (without any other anti-epileptic medication) to epilepsy subjects for the treatment of partial seizures.
- Trial name
- NCT00524030
- Testing
- pregabalin 600 mg/day, pregabalin 150 mg/day
- Where
- 73 sites in United States, Czechia and 2 more
- Volunteers
- 161 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Fibromyalgia, Pregabalin
The Efficacy and Safety of Pregabalin Combined With Venlafaxine in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters.
- Conditions
- Fibromyalgia, Pregabalin, Venlafaxine, Pain
- Trial name
- NCT07186751
- Testing
- Pregabalin, Pregabalin with venlafaxine
- Where
- 2 sites in China
- Volunteers
- 750 people
- Sponsor
- Beijing Tiantan Hospital
Fibromyalgia
Newer Antidepressants in Combination With Pregabalin for Fibromyalgia Syndrome
Background: The investigator hypothesized that the combined use of pregabalin and paroxetine would be associated with comparable Somatic Symptoms Scale-8 (SSS-8) and higher tolerability than amitriptyline or venlafaxine.
- Trial name
- NCT02451475
- Testing
- Amitriptyline, Venlafaxine, Paroxetine
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Scleroderma, Systemic, Sclerosis, Systemic
Pragmatic Clinical Trials in Scleroderma
Systemic Sclerosis (SSc) is an autoimmune connective tissue disease characterized by autoantibodies, fibrosis and microvascular injury and endothelial cell activation that results in vascular damage.
- Trial name
- PCTS (NCT03610217)
- Testing
- Interstitial lung disease induction algorithm, Pulmonary arterial hypertension algorithm, Raynaud's phenomenon algorithm
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University of West London
Fracture; Rib, Multiple
Oral Pregabalin Effect to the Intravenous Morphine in Multiple Fracture Ribs
Determine the effect of using oral pregabalin on the analgesic effects of IV infusion of morphine in patients with multiple fracture ribs.
- Trial name
- NCT03473093
- Testing
- Pregabalin 150mg, Morphine
- Volunteers
- 80 people
- Sponsor
- Assiut University
Nausea
Pregabalin for the Prevention of Chemotherapy Induced Nausea and Vomiting
phase II randomized, double-blind, placebo-controlled trial to investigate whether pregabalin can improve the complete control of nausea and vomiting (primary end point)
- Trial name
- NCT04181346
- Testing
- Pregabalin
- Where
- Brazil
- Volunteers
- 82 people
- Sponsor
- Faculdade de Medicina do ABC
Diabetic Peripheral Neuropathic Pain
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN).
- Trial name
- NCT06628908
- Testing
- Suzetrigine, Pregabalin
- Where
- 76 sites in United States
- Volunteers
- 1,100 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Healthy
Randomized, Open-label, Parallel Study to Evaluate the Pharmacokinetic Characteristics of Pregabalin According to Different Controlled Released Formulations in Healthy Male Subjects
The purpose of this trial is to compare the pharmacokinetic characteristics of YHD1119 A, YHD1119 B, YHD1119 C and Lyrica capsule. YHD1119 A, B, C are controlled released formulations which are made by YUHAN Corporation.
- Trial name
- NCT01420913
- Testing
- Pregabalin
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Postoperative Pain
Pregabalin for Postoperative Pain in Women Undergoing Breast Cancer Surgery
We hypothesize that pregabalin will decrease postoperative pain, as measured by the surrogate markers postoperative pain rating scores and postoperative opioid consumption while improving the quality of recovery following breast…
- Trial name
- NCT00785382
- Testing
- Pregabalin 150 mg
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Healthy
Pharmacokinetic Drug Interaction Between Pregabalin and Thioctic Acid.
A randomized, open-label, six-sequence, three-period, three-treatment, multiple dosing clinical trial to investigate the pharmacokinetic drug interaction between Pregabalin and Thioctic acid after oral administration in healthy…
- Trial name
- NCT01808300
- Testing
- Pregabalin 300mg, Thioctic acid 600mg
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Unimed Pharmaceuticals
Amantadine, Duloxetine
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
This study aims to evaluate the additive effect of Amantadine or Duloxetine to Pregabalin on development of post mastectomy pain syndrome
- Conditions
- Amantadine, Duloxetine, Pregabalin, Mastectomy
- Trial name
- NCT07421427
- Testing
- Pregabalin, Pregabalin + Amantadine, Pregabalin + Duloxetine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Diabetic Peripheral Neuropathy, Fibromyalgia
Pharmacokinetics of Two Formulation of Pregabalin
A Randomized, Single-Dose, Parallel-Group Study to Evaluate the Pharmacokinetic Profiles of Two Formulations of Pregabalin after Oral Administration in Healthy Volunteers under Fasting Conditions
- Conditions
- Diabetic Peripheral Neuropathy, Fibromyalgia, Partial Seizure Disorder
- Trial name
- NCT03712475
- Testing
- Pregabalin
- Where
- Taiwan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Fibromyalgia, Chronic Pain
Functional Neuroimaging in Fibromyalgia Patients Receiving tDCS
The purpose of this study is to evaluate effectiveness and cerebral neuronal ability to adaptation in patients with fibromyalgia who receive pregabalin and transcranial direct current stimulation.
- Trial name
- NCT01904097
- Testing
- Pregabalin, Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postherpetic Neuralgia ( PHN )
Electroacupuncture for PHN: Efficacy and Biomarker Evaluation in a Multicenter, Randomized, Sham-Controlled Trial Protocol
The investigators are conducting a clinical study with the following objectives: to evaluate the clinical efficacy of electroacupuncture combined with pregabalin in treating Postherpetic Neuralgia(PHN); to investigate the…
- Trial name
- NCT06990854
- Testing
- Electroacupuncture (Hans-100A, Nanjing Jisheng Medical Technology, China), Pharmacotherapy：① Pregabalin ( Lyrica™ ，Pfizer Inc. America) ② Methylcobalamin ( Mecobalamin tablets， Weicai (China) Pharmaceutical Co., Ltd， China）
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Dexiong Han
Pain
Evaluate Long-Term Safety and Efficacy of Pregabalin in Patients With Chronic Neuropathic Pain.
Evaluate long-term safety and efficacy of pregabalin in patients with chronic neuropathic pain.
- Trial name
- NCT00141362
- Testing
- Pregabalin
- Volunteers
- 325 people
- Sponsor
- Pfizer
Pain, Postoperative, Arthroplasty, Replacement, Knee
Reducing Postoperative Side Effect of Pregabalin
The purpose of this study was to determine 1) if pregabalin, when given 37.5 mg twice on the day before surgery, would be effective in reducing the early postoperative side effects including dizziness, nausea, vomiting and…
- Conditions
- Pain, Postoperative, Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
- Trial name
- NCT04599894
- Testing
- 37.5mg Pregabalin + 75mg Pregabalin, 75mg Pregabalin
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The First Hospital of Jilin University
Post-operative Chronic Pain
Shifting Pain Modulation From Pro-to Anti-nociceptive
To create a data base that will facilitate the enrichment of the insights regarding post-operative pain development, and to identify those individuals with the potential to develop this kind of pain.
- Trial name
- NCT02672202
- Testing
- Duloxetine, Pregabalin
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Polyneuropathy
Imipramine and Pregabalin Combination in Painful Polyneuropathy
Polyneuropathy of different etiologies is often associated with pain and the standard treatment for this type of pain is gabapentinoids or antidepressants.
- Trial name
- NCT01047488
- Testing
- Imipramine, Pregabalin, Imipramine, pregabalin
- Where
- 3 sites in Denmark
- Volunteers
- 75 people
- Sponsor
- Odense University Hospital
Pain, Neuropathic
Stellate Ganglion Block in Herpes Zoster
Patient who will be presented to Tanta University Hospitals complaining of acute herpes zoster with onset of vesicular eruption less than 7 days will be included in this clinical study.
- Trial name
- NCT04188327
- Testing
- Stellate ganglion block
- Where
- 3 sites in Egypt
- Volunteers
- 208 people
- Sponsor
- Tanta University
Diabetes
Effects of Electromagnetic Therapy Versus Laser Therapy on Peripheral Diabetic Neuropathy
This study are to: Evaluate effect of magnetic therapy on peripheral neuropathy in diabetic patients. Evaluate effect of laser therapy on peripheral neuropathy in diabetic patients.
- Trial name
- NCT03049605
- Testing
- Magnetic therapy, laser therapy, Only medical treatment
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University