Clinical trials: Maltodextrin
Covid19
Live Microbials to Boost Anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Immunity Clinical Trial
This pilot double-blind randomized controlled trial will test the preliminary efficacy of two doses of a combination of live microbials (probiotics) given to boost the immunity of unvaccinated persons previously infected with…
- Trial name
- NCT04847349
- Testing
- OL-1, standard dose, OL-1, high dose
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Hiv, Vaccine Reaction
B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV
The primary objectives of this study are to evaluate the effect of early-life B. infantis Rosell®-33 supplementation in infants exposed to HIV on: gut microbiome composition and diversity at 4 weeks of life markers of intestinal…
- Conditions
- Hiv, Vaccine Reaction, Microbial Colonization, Infant Development
- Trial name
- BifIID (NCT05923333)
- Testing
- B. infantis Rosell®-33
- Where
- South Africa
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Type 2 Diabetes, Atherosclerosis
Effects of Berries and Berry Fractions on Metabolic Diseases
The study hypothesis is that the bioactive compounds of sea buckthorn berries (Hippophaë rhamnoides), their fractions, and bilberries (Vaccinium myrtillus).
- Trial name
- NCT01860547
- Testing
- Bilberries, Sea buckthorn berry, Sea buckthorn phenolic extract
- Where
- Finland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Turku
Obesity
Resveratrol Stimulates Insulin Sensitivity in Subjects With Obesity and Insulin Resistance
There is evidence that resveratrol can improve insulin resistance in rodents and humans with obesity and it can also improve muscle mitochondrial content mediated through activation of AMPK.
- Trial name
- NCT06961279
- Testing
- Resveratrol
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Healthy, Impaired Glucose Tolerance
Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability
The purpose of this study is to determine the short-term effect of a nutritional program consisting of a yerba mate supplement, fiber supplement, and intermittent fasting on glycemic variability in men and women with risk factors…
- Trial name
- NCT05493553
- Testing
- Dietary supplement regimen, Dietary supplement and intermittent fasting regimen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Unicity International, Inc.
Breast Cancer
The Effect of Channa Striata and Curcuma Supplementation on Nutritional Status, Interleukin-6 Levels, and Quality of Life in Patients With Breast Cancer.
Breast cancer is frequently accompanied by chronic inflammation, malnutrition, and reduced quality of life, all of which may compromise treatment response and clinical outcomes.
- Trial name
- CCBreast (NCT07722156)
- Testing
- channa striata and curcuma
- Where
- Indonesia
- Volunteers
- 76 people
- Sponsor
- DINA KEUMALA SARI
Overweight or Obese, Obesity and Overweight
A Trial With EMP16 in Preparation for Late Phase Studies
The goal of this clinical trial is to explore the impact of dietary fibre supplement in the form of Vi-Siblin® S (ispaghula seed coats), together with advice on proper healthy diet, on tolerability during dose-escalation of EMP16…
- Trial name
- POEM (NCT06993428)
- Testing
- EMP16-02 120 mg orlistat/40 mg acarbose, Alli® 60 mg, Vi-Siblin® S
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Empros Pharma AB
Lactose Intolerance
Effect of I31 Probiotic on Lactose Intolerance
This randomized study evaluates the usefulness of the I31 probiotic formula, against placebo, in the treatment of symptoms of lactose intolerance.
- Trial name
- NCT04164394
- Testing
- I31 Probiotic
- Where
- Mexico
- Volunteers
- 48 people
- Sponsor
- Hospital Juarez de Mexico
Malignant Neoplasm, Malignant Neoplasm of Rectum
Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial
The investigators hypothesize that an increase in dietary fiber intake during radiation therapy may provide better long-term intestinal health for the cancer survivor.
- Conditions
- Malignant Neoplasm, Malignant Neoplasm of Rectum, Malignant Neoplasm of Anus, Malignant Neoplasm of Urinary Bladder
- Trial name
- FIDURA (NCT04534075)
- Where
- Sweden
- Volunteers
- 354 people
- Sponsor
- Sahlgrenska University Hospital
Constipation
Dietary Supplementation Effects on Bowel Movement Frequency and Intestinal Biological Markers in Seniors Presenting Slowed Intestinal Transit
This randomized, double-blind, controlled clinical trial among healthy volunteers with infrequent bowel movements but not severe constipation evaluate the effects of a supplementation in "symbiotic" on intestinal transit of…
- Trial name
- NCT04304170
- Testing
- VES002
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CEN Biotech
Inflammatory Bowel Diseases
Treating IBD With Inulin
The purpose of this study is to see how the prebiotic inulin changes the gut bacteria (microbiome) of children and young adults with IBD and determine if this dietary intervention can help reduce disease activity.
- Trial name
- TII (NCT03653481)
- Testing
- Oligofructose-enriched Inulin OI, Maltodextrin
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Children's Hospital of Philadelphia
Sepsis, Systemic Inflammatory Response Syndrome (SIRS)
Effect of Lactiplantibacillus Plantarum DAD-13 on Inflammatory Markers in ICU Sepsis Patients
This study investigated whether giving the probiotic Lactiplantibacillus plantarum DAD-13 to sepsis patients in the intensive care unit (ICU) could help reduce inflammation and improve bowel function.
- Conditions
- Sepsis, Systemic Inflammatory Response Syndrome (SIRS), Critical Illness
- Trial name
- LactoSepsis (NCT07072871)
- Testing
- Lactiplantibacillus plantarum DAD-13
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- PT Royal Medikalink Pharmalab
Irritable Bowel Syndrome
Probiotics for Irritable Bowel Syndrome
The study aims to investigate the effect of probiotics on IBS-patients symptoms compared to placebo, when given for 6 months. By draw the investigators give IBS patients, in the age of 18-50 years, capsules with either probiotics…
- Trial name
- NCT01151657
- Testing
- Probiotics
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Irritable Bowel Syndrome
Effect of Chronic Feeding of Inulin And Methylcellulose on Colonic Fermentation
To determine the effect on tolerance and gas production from chronic feeding of fermentable fibre (inulin) incorporated into a gel forming fibre (methylcellulose) compared with placebo (maltodextrin)
- Trial name
- CINNAMON (NCT06551961)
- Testing
- methylcellulose, inulin, maltodextrin
- Where
- 2 sites in United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Cardiovascular Risk Factor, Lipaemia
Effect of Lactose on Blood Lipids
This study aims to determine to what extent ingestion of free sugars influence postprandial triglyceridaemia in men and women.
- Conditions
- Cardiovascular Risk Factor, Lipaemia, Metabolic Disease
- Trial name
- NCT04924530
- Testing
- Maltodextrin, Sucrose, Lactose
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bath
Growth, Necrotizing Enterocolitis
Bovine Colostrum as a Fortifier Added to Human Milk for Preterm Infants
Very preterm infants (<32 weeks gestation) with very low birth weight (VLBW, <1500 g) show immaturity of organs and have high nutrient requirements forgrowth and development.
- Conditions
- Growth, Necrotizing Enterocolitis, Late-Onset Sepsis, Feeding Intolerance
- Trial name
- FortiColos (NCT03537365)
- Testing
- Bovine Colostrum (BC) / intervention group, FM85 / control group
- Where
- 7 sites in Denmark
- Volunteers
- 252 people
- Sponsor
- Per Torp Sangild
NAFLD
The Role of Microbiome Reprogramming on Liver Fat Accumulation
The purpose of this study is to investigate whether reprogramming the microbiome via soluble fiber supplementation will decrease liver fat in obese individuals.
- Trial name
- MILE (NCT03914495)
- Testing
- Inulin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Diarrhea, Upper Respiratory Infections
Children Immune Functions
The purpose of the planned study is to investigate the effect of heat-treated lactobacilli on diarrhea outcome in healthy children 1-4 years old in a randomized, double-blind, placebo-controlled study.
- Trial name
- NCT01717534
- Where
- 2 sites in Mexico
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Hypertension, Menopause
8 Weeks of L-CIT Supplementation and LIRET on Vascular Function in Hypertensive Postmenopausal Women
The overall objective of this project is to bring forth evidence that L-Citrulline (L-CIT) supplementation and low intensity resistance exercise training (LIRET) alone and combined will improve vascular function and muscle…
- Trial name
- NCT05227781
- Testing
- L-Citrulline
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Dietary Exposure, Metabolic Disturbance
Influence of Tart Cherry Juice Intervention on Vascular Function
Diets containing fruit rich in anthocyanins have been shown (in meta-analyses) to be beneficial for health, but intervention trials have shown inconsistent results.
- Trial name
- NCT04840160
- Testing
- Cherry juice
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northumbria University