Clinical trials: Lidocaine, completed
Lung Diseases
Continuous Erector Spinae Plane Block or Thoracic Epidural Analgesia Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960736
- Testing
- ESP block (Group A), TEA group (Group B)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Chronic Rhinitis
Effects of Radiofrequency Ablation of Posterior Nasal Nerves on Inflammatory Cytokines, Peak Nasal Inspiratory Flow, and Nasal Blood Flow in Patients With Chronic Rhinitis
The purpose of this study is to assess the effectiveness of radiofrequency ablation (RFA) of the posterior nasal nerve (PNN) in chronic rhinitis (CR) patients by comparing patient reflective total nasal symptom score (rTNSS) and…
- Trial name
- NCT05648565
- Testing
- Radiofrequency ablation (RFA)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- The University of Texas Health Science Center, Houston
Voice Disorders
Brain Mapping of Voice Control
Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the…
- Trial name
- NCT00066911
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Covid19
Xylocaine to Freeze During Unpleasant Nasopharyngeal Swabs
Since the beginning of the COVID-19 pandemic, nasopharyngeal swabs (NPS) have been recommended to detect the virus. This procedure has been reported to be painful by 85% of children The aim of the study was to assess whether…
- Trial name
- Xylofuns (NCT04901065)
- Testing
- Xylocaine
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Evelyne D.Trottier
Sacroiliac Joint Somatic Dysfunction, Sacroiliac Joint Pain
Combination of Fluoroscopy and Ultrasonography Guidance in Sacroiliac Joint Injections. A Randomised Controlled Trial
The primary purpose of this study is to investigate the effect of the application of sacroiliac joint injection guided by combination of ultrasonography and fluoroscopy on the duration of the procedure and the amount of radiation…
- Trial name
- NCT05944861
- Testing
- Combined ultrasonography and flouroscopy guided injeciton, Flouroscopy guided injection
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Pain, Acute, Laceration
Prospective Evaluation of Topical Analgesia for Laceration Repair in the Emergency Department
The purpose of this study is to determine if topical analgesia using a lidocaine and prilocaine cream improves pain scores compared to the usual local anesthesia using subcutaneous 1% lidocaine and adrenalin injected near the…
- Trial name
- NCT03071601
- Testing
- Lidocaine-Prilocaine Cream 2.5-2.5%, Lidocaine 1% Epinephrine 0.005mg/mL solution
- Where
- 2 sites in France
- Volunteers
- 132 people
- Sponsor
- Centre Hospitalier le Mans
Ankle Fractures
WALANT and Spinal Anesthesia Comparison of Clinical Result in Ankle Fractures
The application of the WALANT technique for foot and ankle surgery (joint fusion, implant removal and tendon repair, etc.) is limited. In our study, using the WALANT technique for ARIF in ankle fractures.
- Trial name
- NCT06077344
- Testing
- WALANT in Ankle Fractures (Wide-Awake Local) Anesthesia No Tourniquet) and Applied Under Spinal Anesthesia Comparison of Clinical Results of Surgical Treatment;ANT Procedure comparation, Applied Under Spinal Anesthesia of Clinical Results of Surgical Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Symptomatic Irreversible Pulpitis
Assessment of Local Anaesthesia Effectiveness in Symptomatic Irreversible Pulpitis
This study aims to evaluate the comparative efficacy of two different local anaesthetic agents for supplemental buccal infiltration after a failed inferior alveolar nerve block in achieving profound pulpal anaesthesia for…
- Trial name
- LA AGENTS (NCT06862570)
- Testing
- 2% lignocaine with epinephrine 1.8 ml(36mg/ml lignocaine HCL, epinephrine bitartrate 0.0324mg/ml), 4% Articaine with epinephrine 1.7 ml (40mg/ml Articaine HCL, epinephrine bitartrate 0.018 mg/ml)
- Where
- Pakistan
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- 28 Military Dental Centre Lahore
Anesthesia
Anesthetic Efficacy in Irreversible Pulpitis
The purpose of this study was to compare the anesthetic efficacy of articaine, lidocaine and mepivacaine in patients with irreversible pulpitis of mandibular molar.
- Trial name
- NCT02054767
- Testing
- Intervention: inferior alveolar nerve block injection
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postoperative Pain
A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abdominal Surgery
The primary purpose of this study is to evaluate the effects of lidocaine/epinephrine test dose administration on the PK profile of a single epidural dose of DepoDur (extended-release epidural morphine) in patients undergoing…
- Trial name
- NCT00728832
- Testing
- DepoDur (extended-release epidural morphine)
- Volunteers
- 39 people
- Sponsor
- EKR Therapeutics, Inc
Lip Augmentation
Postmarket Study of JUVÉDERM VOLBELLA™ With Lidocaine in the Lips
A prospective, multicenter postmarket study of the use of JUVÉDERM VOLBELLA™ with Lidocaine in the lips.
- Trial name
- NCT01629134
- Testing
- Crosslinked hyaluronic acid gel
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Allergan Medical
Chest Tube Removal, Children
The Effects of EMLA Cream and Cold Application on Pain, Fear and Vital Signs Before Chest Tube Removal in Children
This study is being conducted to determine the effect of EMLA cream and cold application on pain, fear and vital signs before chest tube removal in children aged 7-18 years.
- Conditions
- Chest Tube Removal, Children, Pain Management
- Trial name
- NCT06913855
- Testing
- EMLA Cream, Cold application
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul Medeniyet University
Anesthesia, Spinal Puncture
Intravenous Fentanyl or Local Anesthetic Infiltration for Pain Reducing During Spinal Needle Insertion
Background and Objectives: Spinal puncture is painful procedure which may cause patient refusal of spinal anesthesia in future surgery.
- Trial name
- NCT01157247
- Testing
- Comparison of intravenous fentanyl and local anesthetic infiltration in pain reducing during spinal needle puncture
- Where
- Croatia
- Volunteers
- 88 people
- Sponsor
- Croatian Society of Regional Anesthesia and Analgesia
Postoperative Recovery
Effect of Three Different Postcesarean Analgesic Techniques on QbsQor-10 Score
The aim of this study is to evaluate the effects of three different postsesarean analgesia techniques, including instillation of local anesthetic into the peritoneum with infiltration into all layers of the anterior abdominal…
- Trial name
- NCT06341049
- Testing
- Intraperitoneal local anasthetic application + local anesthetic wound infiltration, Intrathecal morphine application, Quadratus lumborum block tip 1 application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ataturk University
Acute Pain
Intravenous Lidocaine in Total Knee Replacement
Osteoarthritis of knees and hips is a common medical problem present in elderly, which poses significant impairment to their mobility, independence, and quality of life.
- Trial name
- NCT03597776
- Testing
- Lidocaine, Saline
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- The University of Hong Kong
Pain
The Neurobiology of Expectancy and Pain Perception
This study will use using fMRI (functional Magnetic Resonance Imaging) to elucidate how contextual learning/expectation relieves or aggravates pain experience in the same cohort of subjects and the same study session.
- Trial name
- NCT01575106
- Testing
- Heat pain applied using TSA or CHEPS
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Analgesia, Urolithiasis
Efficacy of Pethidine, Ketorolac And Xylocaine Gel As Analgesics For Pain Control In Shockwave Lithotripsy
A randomised prospective trial comparing the efficacy of pethidine, Ketorolac, and Xylocaine gel as analgesics for pain control in shockwave lithotripsy.
- Trial name
- NCT03032458
- Testing
- Pethidine, Ketorolac, Xylocaine Gel
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Mansoura University
Chronic Pain
A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Pain
This multi-center, phase 2, randomized, single-blind, three-arm, active-controlled study is comparing repeat doses, every 28 days, of standard of care (SOC) plus ST-01 against SOC plus 1% lidocaine HCL in men experiencing chronic…
- Trial name
- NCT05707208
- Testing
- ST-01, 1% Lidocaine HCL
- Where
- 8 sites in Canada
- Volunteers
- 63 people
- Sponsor
- Sustained Therapeutics Inc.
PONV, Opioid Sparing Anaesthesia
Opioid Sparing Anaesthesia for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
In spite of multimodal analgesic strategies, which consist of opioids, dexamethasone, non-steroidal anti-inflammatory drugs, and local anesthetics applied into the surgical wound, postoperative pain and postoperative nausea and…
- Trial name
- NCT04706897
- Testing
- Dexmedetomidine, ketamine and lidocaine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Scleroderma
Effectiveness and Safety of Lidocaine for Scleroderma
Scleroderma, or systemic sclerosis, is a chronic connective tissue disease generally classified as one of the autoimmune rheumatic diseases.
- Trial name
- NCT00740285
- Testing
- Lidocaine 2% without vessel constrictor
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Federal University of São Paulo
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