Clinical trials: Lidocaine, open to volunteers
Frozen Shoulder, Adhesive Capsulitis
USG-Guided Shoulder Injections in Frozen Shoulder
Frozen shoulder (adhesive capsulitis) is characterized by pain and a progressive restriction of both active and passive shoulder range of motion, significantly impairing daily activities and quality of life.
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Shoulder Pain, Nociplastic Pain
- Trial name
- NCT07493213
- Testing
- USG-guided suprascapular nerve block, USG-Guided suprascapular nerve block plus subacromial injection.
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Knee Arthritis Osteoarthritis
Comparing Treatment of Knee Osteoarthritis With Triamcinolone Injections Using 40mg With Landmark Guidance and 20mg With Ultrasound Guidance
The purpose of this study is to determine whether a lower dose of corticosteroid injection with ultrasound-guidance for the treatment of knee osteoarthritis can be as effective as a higher dose that is landmark-guided.
- Trial name
- PRECISION-Knee (NCT07544576)
- Testing
- Triamcinolone knee injection without ultrasound guidance, Triamcinolone knee injection with ultrasound guidance
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Sosi Dzhugarian
Colorectal Carcinoma, Analgesia, Postoperative
Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery
Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing…
- Conditions
- Colorectal Carcinoma, Analgesia, Postoperative, Laparotomy
- Trial name
- NCT06935708
- Testing
- Intrathecal Morphine, Epidural Analgesia
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- Meri Mirceta
Premature Ejaculation
Hyaluronic Acid vs Botulinum Toxin Injection in Treatment of Lifelong Drug-Resistant Premature Ejaculation: Randomized Study
Premature ejaculation (PE) is one of the most common male sexual dysfunctions, often resistant to conventional pharmacological and behavioral treatments.
- Trial name
- NCT07236632
- Testing
- Botulinum toxin type A, Hyaluronic acid
- Volunteers
- 80 people
- Sponsor
- Benha University
Vaso-Occlusive Pain Episode in Sickle Cell Disease
Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease
The purpose of the study is to determine whether adding lidocaine to standard of care in pain management during severe vaso-occlusive crisis has an effect on the cumulative opioid consumption expressed as morphine milligram…
- Trial name
- LidoVOC (NCT07274254)
- Testing
- Lidocain, Standard of care
- Where
- 12 sites in France, Guadeloupe
- Volunteers
- 104 people
- Sponsor
- Nantes University Hospital
Lung Adenocarcinoma, Lung Abscess
Evaluation of Different Sizes of Left-Sided Double-Lumen Tubes for Thoracic Surgery in a Tertiary Level Teaching Hospital
Double lumen tubes (DLT) have become standard of care for one lung ventilation in thoracic and esophageal surgeries. Selection of accurate size of DLT is important to achieve proper one lung ventilation, prevent trauma to airway…
- Trial name
- NCT07373171
- Testing
- Intubation of patients undergoing thoracic surgery with left sided double lumen tube
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University, Nepal
Pain (Visceral, Somatic, or Neuropathic)
Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block During Extraction of Posterior Mandibular Teeth
This randomised control trial will compare the efficacy of conventional buccal nerve block versus buccal trunk block using visual analogue scale to evaluate pain and additional anesthesia injection during extraction of mandibular…
- Trial name
- Buccal Trunk (NCT07330518)
- Testing
- Conventional Buccal Nerve Block, Buccal Nerve Trunk Block
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Watim Medical & Dental College
Lateral Epicondylitis
Comparative Effectiveness of Ultrasound-Guided Tenoxicam and Corticosteroid Injections for Lateral Epicondylitis
This prospective, randomized, comparative clinical study aims to compare the effectiveness of ultrasound-guided corticosteroid and tenoxicam injections in patients with lateral epicondylitis.
- Trial name
- NCT07883876
- Testing
- methylprednisolone acetate, tenoxicam
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara Etlik City Hospital
Gonorrhea Infection
500-mg Versus 1000-mg Ceftriaxone for Uncomplicated Gonorrhea Infection
This is a study to compare the treatment effect of different doses of ceftriaxone for gonorrhea.
- Trial name
- NCT07710118
- Testing
- ceftriaxone 500-mg, ceftriaxone 1000-mg
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Adhesive Capsulitis, Frozen Shoulder
Adhesive Capsulitis: Prospective Analysis of Efficacy and Financial Impact for Use of Physical Therapy in Treatment
The purpose of this study is to identify individuals 18 or older who have diagnostic presentation of adhesive capsulitis and randomize them into two arms, distinguished by use of physical therapy and steroid injections compared…
- Conditions
- Adhesive Capsulitis, Frozen Shoulder, Shoulder Frozen
- Trial name
- NCT02283996
- Testing
- Physical Therapy, Depot Methylprednisolone
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Thyroid Surgeries
Comparative Study of Ultrasound Guided Superficial vs Intermediate Cervical Plexus Block for Perioperative Analgesia in Thyroid Surgeries.
The investigator compare the analgesic efficacy of ultrasound-guided subcutaneous cervical plexus block vs ultrasound-guided intermediate cervical plexus block pre-intra and postoperative thyroid surgery
- Trial name
- NCT07843589
- Testing
- Ultrasound guided superficial cervical plexus block, ultrasound guided intermediate cervical plexus block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Menoufia University
Perioral Wrinkles, Crow's Feet
Prospective, Non-interventional Study Assessing Perioral Rejuvenation Procedure
The goal of this observational study is to learn how a perioral rejuvenation procedure affects perioral line severity and lip volume over time in adults undergoing routine aesthetic treatment in a single clinical center.
- Conditions
- Perioral Wrinkles, Crow's Feet, Lip Volume Enhancement, Lip Aging
- Trial name
- NCT07398768
- Testing
- Saypha® Rich, Saypha® Filler Lidocaine
- Where
- Austria
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yuvell
Myofascial Pain of Upper Trapezius Muscle
Comparison of the Effectiveness of Dry Needling Versus the Combination of Dry Needling and Local Anesthetic Injection in Myofascial Pain Syndrome of the Upper Trapezius Muscle: A Sham-Controlled, Randomized Clinical Trial
This study was designed to compare the effectiveness of three different treatment protocols in patients diagnosed with myofascial pain syndrome of the upper trapezius muscle.
- Trial name
- NCT07456735
- Testing
- Dry Needling, Local Anesthehetic Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Emre Ata, Assoc Prof
Pancreatoduodenectomy, Pain Management
Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy
The goal of this clinical trial is to determine whether continuous nefopam administration, as part of a multimodal analgesia strategy, reduces opioid consumption and improves patient satisfaction after pancreatoduodenectomy.
- Conditions
- Pancreatoduodenectomy, Pain Management, Opioid Analgesia, Multimodal Analgesia
- Trial name
- NCT07423650
- Testing
- Nefopam 120mg/day infusion, Lidocaine Infusion, Peridural
- Where
- Romania
- Volunteers
- 93 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Fentanyl, Ketorolac
Fentanyl Versus Ketorolac as an Adjuvant to Peribulbar Block for Anterior Segment Surgeries
This study aims to compare the efficacy of ketorolac and fentanyl as adjuvants to local anesthetics for anterior segment surgeries of the eye.
- Conditions
- Fentanyl, Ketorolac, Adjuvant, Peribulbar Block
- Trial name
- NCT07141589
- Testing
- Lidocaine + Bupivacaine + Hyaluronidase, Fentanyl + Lidocaine + Bupivacaine + Hyaluronidase, Ketorolac + Lidocaine + Bupivacaine + Hyaluronidase
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Cairo University
Electrical Storm, VT
Percutaneous Stellate Ganglion Block as First Line Treatment in Patients With Electrical Storm: the STAR 2 Study
Electrical storm (ES) is a life-threatening condition characterized by recurrent episodes of ventricular tachycardia (VT) or ventricular fibrillation (VF) requiring anti-tachycardia pacing or defibrillator shocks.
- Conditions
- Electrical Storm, VT, VF, Ventricular Arrhythmia
- Trial name
- STAR 2 (NCT07841080)
- Testing
- L-PSGB first
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Organ Dysfunction, Organ Support
Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction
Acute pancreatitis may cause early respiratory, cardiovascular, or renal dysfunction and may require intensive care and organ support.
- Conditions
- Organ Dysfunction, Organ Support, Acute Pancreatitis (AP)
- Trial name
- TEA-APOD (NCT07697690)
- Testing
- Thoracic Epidural Analgesia With Ropivacaine, conventional analgesia
- Volunteers
- 150 people
- Sponsor
- First People's Hospital of Chenzhou
Mohs Micrographic Surgery, Anesthesia, Local
Local Anesthetic Clinical Trial
To compare several local anesthetics when used during dermatological surgery.
- Trial name
- NCT07601750
- Testing
- Lidocaine, Bupivacaine Hydrochloride, Mepivacaine Hydrochloride
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Baylor Research Institute
Chronic Pain, Perineural Analgesia
Perineural Prolotherapy in Chronic Knee Osteoarthritis Pain.
The aim of this study is to test whether the addition of dextrose to perineural injections is superior to local anesthetic alone, as some initial data have indicated.
- Conditions
- Chronic Pain, Perineural Analgesia, Prolotherapy, Knee Osteoarthritis
- Trial name
- NCT07245121
- Testing
- Dextrose 5% and Lidocaine, Lidocaine
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Refractory Migraine, Headache
Localized Injection of Lidocaine Via the Middle Meningeal Artery for Headache Treatment
The goal of this clinical trial is to test whether injecting lidocaine into two blood vessels of the brain can help treat chronic headaches (migraines)
- Trial name
- LIGHT 2 (NCT07361549)
- Testing
- Lidocaine (drug), Saline
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Daniel A Tonetti, MD