Clinical trials: Intervention
Developmental Delay (Disorder)
Mindful Movement And GAME BASED Training In Developmental Delay
Developmental delay in children is characterized by delayed acquisition of cognitive, motor, language, and social skills and is commonly associated with conditions such as cerebral palsy, autism spectrum disorder, and genetic…
- Trial name
- MINDGAME (NCT07575165)
- Testing
- Mindful movement, Game based training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Locally Advanced Esophageal Squamous Cell Carcinoma, Sintilimab
Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell Carcinoma
At present, concurrent chemoradiotherapy (cCRT) with platin-based dual-drug regimen is the standard treatment for inoperable, locally advanced esophageal cancer in patients with a good performance status.
- Conditions
- Locally Advanced Esophageal Squamous Cell Carcinoma, Sintilimab, Radiotherapy, Concurrent Chemoradiotherapy
- Trial name
- NCT06342167
- Testing
- Radiotherapy, Programmed Cell Death Protein 1 Inhibitor, Immunonutrition support
- Where
- 10 sites in China
- Volunteers
- 57 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Microvascular Dysfunction, Hypertrophic Obstructive Cardiomyopathy
Association Between Microvascular Resistance and Outcomes in Patients With Obstructive Hypertrophic Cardiomyopathy
About 60% of patients with hypertrophic cardiomyopathy have microvascular dysfunction. Microvascular dysfunction is directly related to prognosis in hypertrophic cardiomyopathy.
- Conditions
- Microvascular Dysfunction, Hypertrophic Obstructive Cardiomyopathy, Microcirculation Resistance
- Trial name
- NCT05671367
- Where
- China
- Volunteers
- 340 people
- Sponsor
- China National Center for Cardiovascular Diseases
Lateral Epicondylitis
Comparison of Muscle Energy Technique and Oscillating Energy Manual Therapy in Chronic Lateral Epicondylitis
Lateral epicondylitis (LE) is a painful musculoskeletal condition caused by overuse. The condition is also called tennis elbow because it affects 50% of tennis players, notably beginners learning the one-handed backhand.
- Trial name
- NCT05354167
- Testing
- muscle energy technique, oscillating manual energy therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Carcinoma, Non-Small-Cell Lung
A Pilot Study of Response-Driven Adaptive Radiation Therapy for Patients With Locally Advanced Non-Small Cell Lung Cancer
Successful treatment of lung cancer with radiation therapy requires that the physicians determine exactly where the tumor is in the patient's body and seek to limit any unnecessary radiation to normal parts of the body.
- Trial name
- NCT02492867
- Testing
- Response-driven Adaptive Radiation Therapy, Carboplatin, Paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- University of Michigan Rogel Cancer Center
Adolescent Obesity, Hypertension,Essential
Treatment and Handling Severe Obesity-Related Comorbidities in Adolescents Through Exercise
The main objective of this project is to analyze the effect of a tailor-made, one-to-one, exercise program (aiming to treat and handle obesity-related comorbidities in adolescents with severe obesity at high risk of…
- Conditions
- Adolescent Obesity, Hypertension,Essential, Non-Alcoholic Fatty Liver Disease, Dyslipidemias
- Trial name
- THOR-X (NCT06520800)
- Testing
- Treatment and handling obesity-related comorbidities in adolescents through exercise
- Volunteers
- 24 people
- Sponsor
- University of Lisbon
Mental Health Issue
UNIPDES- An Internet-Based Transdiagnostic Intervention for College Students' Psychological Symptoms
This study is a randomised clinical trial. This study evaluates the effect of an internet-based intervention developed based on a transdiagnostic cognitive behavioural approach on psychological symptoms of university students.
- Trial name
- UNIPDES (NCT06245200)
- Testing
- UNIPDES - Internet Based Intervention - GUIDED, UNIPDES - Internet Based Intervention - UNGUIDED
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Anadolu University
Frailty, Thoracic Surgery
A Frailty-specific Prehabilitation Program for Mild to Moderately Frail Patients Undergoing Cardiac Surgeries/Procedures
The purpose of this study is to investigate the effects of the frailty-specific prehabilitation program on functional capacity, frailty, cardiac-specific functional status, serum albumin level, high-sensitivity C-reactive protein…
- Trial name
- NCT07824700
- Testing
- Frailty-specific prehabilitation program
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- The University of Hong Kong
Postoperative Pain
ssTAP vs TAP Catheters in TAH
Prospective, randomized study comparing local wound infiltration with local anesthetic (LA) versus single injection TAP blocks (ssTAP) with LA versus continuous TAP block (TAP caths) catheters with LA for treatment of…
- Trial name
- NCT02525900
- Testing
- Wound Infiltration, TAP Blocks, TAP Catheters
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Arkansas
ADL
Effect of Intensified Occupational Therapy on Basic Activities of Daily Living
The objective is to investigate the effect of an intensified occupational therapy intervention on independence in basic activities of daily living (ADL) in subjects with stroke
- Trial name
- NCT05638607
- Testing
- Intensified occupational therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Post COVID-19
A Telemedicine Brief Mindfulness Intervention in Post-COVID-19
Background: Several studies suggest that SARS survivors still presented with high levels of psychological distress overall at 1, 3, 12, and 18 months after hospital discharge.
- Trial name
- NCT05175807
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Plantar Fascitis, Fat Pad Syndrome
Offloading Device for Post Surgical Foot Procedures
Study goals are to determine if a novel post-surgical foot offloading device can reduce post-operative pain and expedite the return to daily activity following fat grafting.
- Trial name
- NCT03873207
- Testing
- PopSole™ offloading device, padded insole
- Where
- United States
- Sponsor
- Jeffrey A. Gusenoff, MD
Hemispatial Neglect
Active Cue-Training in Neglect
The presented study investigates standardized visual cueing in reading and visual spatial task as a treatment method for spatial neglect.
- Trial name
- NCT02945592
- Testing
- Cueing
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Klinikum Bremen Ost
Medication-related Osteonecrosis of the Jaw (MRONJ)
Early Warning and Risk Prediction of Medication-Related Osteonecrosis of the Jaw
This prospective observational cohort study aims to develop and evaluate an early warning and risk prediction model for medication-related osteonecrosis of the jaw (MRONJ) based on multimodal data fusion.
- Trial name
- NCT07691892
- Volunteers
- 310 people
- Sponsor
- Hospital of Stomatology, Wuhan University
Amputation; Traumatic, Leg, Lower
Transtibial Osseointegration
Purpose: Aim 1: Quantify soft tissue complications and infections of service members with transtibial amputations treated with OPRA OI and compare them to transfemoral OI service members.
- Trial name
- TOSS (NCT06636136)
- Testing
- OPRA
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Walter Reed National Military Medical Center
Health Knowledge, Attitudes, Practice
Impact of the Financial Inclusion Improves Sanitation and Health
The goal of this interventional study is to evaluate the impacts of Financial Inclusion improvement sanitation and Health (FINISH) interventions in Kenya's Homa Bay County and Uganda's Kamwenge District among children under five.
- Trial name
- FINISH (NCT06356636)
- Testing
- Financial Inclusion Improves Sanitation and Health
- Where
- Kenya
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- Amref Health Africa
Varicose Ulcer, Varicose Veins of Lower Limb
Venous Ulcer: Endovenous Radiofrequency Treatment Trial
The aim of this study is to analyze the effect of intravenous therapy with radiofrequency for superficial and perforating venous insufficiency versus compression therapy with multilayer banding in patients with active venous…
- Conditions
- Varicose Ulcer, Varicose Veins of Lower Limb, Saphenous Vein Injury
- Trial name
- VUERT (NCT03293836)
- Testing
- Radiofrequency ablation, Multilayer Compressive Bandage
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Juliana Puggina
Enamel Demineralization, White Spot Lesions
Silver Nanoparticle-Coated Orthodontic Brackets for Preventing Enamel Demineralization
The goal of this clinical trial is to learn whether orthodontic brackets coated with silver nanoparticles can help prevent early damage to tooth enamel in people receiving fixed braces.
- Trial name
- AgBracket (NCT07707336)
- Testing
- Silver Nanoparticle-Coated Stainless Steel Orthodontic Brackets, Conventional Stainless Steel Orthodontic Brackets
- Where
- United Arab Emirates
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ajman University
Vulvar Cancer
Study of Near-Infrared Imaging With Indocyanine Green for Detection of Sentinel Lymph Nodes in People With Vulvar Cancer
The purpose of this study is to compare two types of imaging for sentinel lymph node (SLN) mapping in people with early-stage vulvar cancer.
- Trial name
- NCT06127836
- Testing
- ICG guided sentinel lymph node biopsy
- Where
- 8 sites in United States
- Volunteers
- 22 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Coronary Syndrome, Coronary Artery Disease
Feasibility of a Deep Learning-based Algorithm for Non-invasive Assessment of Vulnerable Coronary Plaque
The primary objective of this study is to assess the accuracy in terms of sensitivity, specificity, negative and positive predicted values of the DL-based algorithm with respect to correct identification of the plaque and…
- Conditions
- Chronic Coronary Syndrome, Coronary Artery Disease, Stable Angina, Acute Coronary Syndrome
- Trial name
- FOCUS DL (NCT06186336)
- Testing
- Deep Learning-based Vulnerable Plaque Detection and Assessment Tool
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- GE Healthcare
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