Clinical trials: Best Practice
Clinical Audit, Quality Improvement
Impact Evaluation of the Therapeutic Initiative's Type 2 Diabetes in Older Adults Portrait and Therapeutics Letter
The goal of this randomized trial is to learn if educational materials and personalized prescribing portraits change how clinicians in British Columbia (BC), Canada treat older adults with type 2 diabetes (T2DM).
- Conditions
- Clinical Audit, Quality Improvement, T2DM (Type 2 Diabetes Mellitus)
- Trial name
- NCT06733805
- Testing
- Portrait + Therapeutics Letter
- Where
- Canada
- Volunteers
- 515 people
- Sponsor
- University of British Columbia
Adolescent Idiopathic Scoliosis
The Effect of Conservative Treatment on Perceptual and Cognitive Asymmetry in Scoliosis
Adolescent idiopathic scoliosis (AIS) patients have been found to exhibit cortical asymmetry. This study aimed to examine the impact of conservative treatments on perceptual and cognitive asymmetry in the auditory system assessed…
- Trial name
- NCT06141759
- Testing
- Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Substance Use Disorders
Substance Use Prevention for Youth With Parents in Recovery
Risk for substance use disorder (SUD) begins early in the life course. Although preventing and decreasing illicit and nonmedical drug use among youth is an urgent public health priority, there are currently few evidence-based…
- Trial name
- NCT05397691
- Testing
- Modified Family Talk, Control-like parameter estimation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Brown University
Rheumatoid Arthritis
Effectiveness of Therapeutic Fasting and Specific Diet in Patients With Rheumatoid Arthritis
The aim of this trial is an evaluation of the effectiveness of fasting and a subsequent diagnosis-specific diet change in patients with rheumatoid arthritis in respect to improving rheumatic symptoms and further to investigate…
- Trial name
- NutriFast (NCT03856190)
- Testing
- Fasting and plant-based nutrition, Standard Nutrition Counselling
- Where
- 2 sites in Germany
- Volunteers
- 53 people
- Sponsor
- Charite University, Berlin, Germany
Suicide, Suicide, Attempted
Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care
This study is being completed to examine different combinations of technology-augmented strategies to identify an effective Adaptive intervention (AI) addressing post-discharge suicide risk with high implementation potential.
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Self Harm
- Trial name
- NCT05282225
- Testing
- MI- Safety Plan, Texts messages, Monitoring
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Michigan
Hearing Loss
Mindfulness Intervention and Symptom Variability in Hearing
The purpose of this study is to investigate the efficacy of mindfulness and placebo treatments on hearing improvement. More specifically, the researchers will be investigating whether the following variables impact the…
- Trial name
- NCT04281225
- Testing
- Attention to Variability (ATV)
- Where
- United States
- Sponsor
- Harvard University
Hypertension
Hypertension Management Using Remote Patient Monitoring: Study 2
The investigators will conduct a pragmatic pilot test of a remote patient monitoring system (RPM) for blood pressure measurement for Medicare patients with hypertension with and without the support of a care management program.
- Trial name
- NCT04764318
- Testing
- Remote patient monitoring for hypertension, Remote patient monitoring with care management
- Where
- United States
- Volunteers
- 17,290 people
- Sponsor
- Northwestern University
Opioid-Related Disorders
Improving Health and Employment Outcomes Through Workplace Opioid Policies
Evaluate the feasibility of implementing workplace opioid guidelines in the construction trades; define and collect measures of implementation and efficacy.
- Trial name
- NCT05387408
- Testing
- Best Practice Health and Employment Opioid-related Policies
- Where
- United States
- Volunteers
- 4,939 people
- Sponsor
- Washington University School of Medicine
Dietary Habits, Childhood Obesity
Integrating Food Rx With Best Feeding Practices With EFNEP
To assess feasibility and acceptability of of integrating Food Rx and Best Feeding Practices with EFNEP participants via a pilot study.
- Conditions
- Dietary Habits, Childhood Obesity, Food Selection, Feeding Behavior
- Trial name
- NCT05881759
- Testing
- BEST study - Nutrition education only, BEST study - Nutrition education and feeding practices, BEST study - Nutrition education, feeding practices, and Food Rx
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Stress, Coping Skills
Parental Health Decision-making for Children During the COVID-19 Pandemic
Background: As major decision-maker for children's wellbeing, parents play a vital role in decisiding on a wide range of health-related issues including vaccination.
- Trial name
- NCT05298865
- Testing
- Positive imagination stimulation, Neutral recall message
- Where
- Hong Kong
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Clinical Stage II HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage III HPV-Mediated (p16-pos) Oropharyngeal Carcinoma
A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation
This clinical trial tests whether adding the use of a pneumatic compression system with manual lymphatic drainage versus manual lymphatic drainage alone in treating patients with lymphedema after chemoradiation for stage II-IV…
- Conditions
- Clinical Stage II HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage III HPV-Mediated (p16-pos) Oropharyngeal Carcinoma, Clinical Stage IV HPV-Mediated (p16-pos)Oropharyngeal Carcinoma, Head and Neck Carcinoma
- Trial name
- NCT05512767
- Testing
- Best Practice, Consensus Auditory-Perceptual Evaluation of Voice, Diagnostic Imaging
- Sponsor
- Mayo Clinic
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial
This clinical trial evaluates whether geriatric assessment-driven interventions with supportive care (GAIN-S) using telemedicine can be used to identify areas of vulnerability (weakness) in older adults with cancer and guide…
- Trial name
- NCT06022965
- Testing
- Best Practice, Comprehensive Geriatric Assessment, Electronic Health Record Review
- Where
- 3 sites in United States
- Volunteers
- 216 people
- Sponsor
- City of Hope Medical Center
Mental Health Care, AMBIT
My Avenue to helP - Adaptive Mentalization-based Integrative Treatment Compared to Management as Usual for Youths With Multiple Problems: a Non-Randomized Controlled Feasibility Trial
My Avenue to HelP (MAP) is a non-randomized feasibility study testing the implementation of a cross-sectoral collaboration targeted youths, aged 12-17 years, with multiple social and psychological problems.
- Conditions
- Mental Health Care, AMBIT, Adaptive Mentalization-Based Integrative Treatment, Child and Adolescent Psychiatry
- Trial name
- MAP (NCT06886165)
- Testing
- My Avenue to HelP, Management as Usual
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Pia Jeppesen
Opioid Use Disorder
Opioid Use and Criminal Justice: Intervening to Improve the Outcomes of Women
Opioid-related overdose deaths and incarceration rates have skyrocketed and have disproportionately affected women. Despite having a higher burden of substance use disorders and HIV/AIDS than criminal justice-involved (CJI) men…
- Trial name
- NCT06682364
- Testing
- Trauma-informed case management for women who use drugs, CRS Only Intervention
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Abenaa Jones, Ph.D.
Alzheimer Disease, Hearing Loss
Early Age-Related Hearing Loss Investigation (EARHLI)
Early Age-Related Hearing Loss Investigation (EARHLI) is a single site study that will randomize late middle age adults to either a hearing intervention (including hearing aids) or a health education intervention.
- Conditions
- Alzheimer Disease, Hearing Loss, Cognitive Impairment
- Trial name
- EARHLI (NCT06174038)
- Testing
- Hearing Intervention, Health Education Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Nozin in Preventing Respiratory Viral Infections in Patients Undergoing Stem Cell Transplant, PREV-NOSE STUDY
This phase I trial studies the side effects of Nozin in preventing respiratory viral infections in patients undergoing stem cell transplant.
- Conditions
- Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Solid Neoplasm
- Trial name
- NCT04060849
- Testing
- Nozin, Best Practice
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Fred Hutchinson Cancer Center
Smoking Behaviors
Evaluation of a Novel mHealth Intervention for People Who Are Ambivalent About Quitting Smoking
The goal of this study is to compare the effectiveness of two smoking cessation programs to determine which better helps people change their smoking behavior, the control or the experimental intervention? Both interventions…
- Trial name
- GEMS (NCT07459621)
- Testing
- Control Intervention, Experimental Intervention
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Kaiser Permanente
Prehabilitation, Pancreas Cancer
Preoperative Optimisation of Modifiable Risk Factors in Surgery of the Pancreas
The goal of this stepped-wedge randomized controlled trial is to investigate whether implementation of a best practice program for preoperative optimisation (prehabilitation program) with a focus on screening, assessment, and…
- Conditions
- Prehabilitation, Pancreas Cancer, Surgery, Postoperative Complications
- Trial name
- PROMISE-P (NCT05851534)
- Testing
- Preoperative optimisation program
- Where
- 13 sites in Netherlands
- Volunteers
- 2,575 people
- Sponsor
- Maastricht University Medical Center
Knowledge, Attitudes, Practice
MAP for Coaches: Translating Sports Injury Prevention Knowledge to Youth Sport Coaches
The goal of this clinical trial is to test the effectiveness of the MAP for Coaches, a web-based Musculoskeletal Athletic injury Prevention training course, in youth sport coaches.
- Trial name
- MAP (NCT05718063)
- Testing
- MAP for Coaches - Complete Course, Map for Coaches - Overview
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
Does the Use of a Genomic Tumor Board Increase the Number of Patients Who Receive Genome-Informed Treatment
This clinical trial studies how well an educationally enhanced genomic tumor board (EGTB) intervention works to increase the number of patients with solid tumors that have come back (recurrent), do not respond to treatment…
- Conditions
- Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Malignant Solid Neoplasm
- Trial name
- NCT05455606
- Testing
- Best Practice, Chart Abstraction, Educational Intervention
- Where
- 72 sites in United States, Puerto Rico
- Volunteers
- 1,284 people
- Sponsor
- SWOG Cancer Research Network