Clinical trials: Amoxicillin
Helicobacter Pylori Infection
LOAD VS Levofloxacine Concomitant
Comparison Efficacy of two weeks Therapy with Doxycycline,levofloxacine,Tinadizole Versus Levofloxacine,Tinadizole,Amocillin on Eradication of Helicobacter Pylori in Syrian population.
- Trial name
- NCT04626193
- Testing
- Doxycycline, Levofloxacin 500mg
- Where
- Syria
- Volunteers
- 80 people
- Sponsor
- Damascus Hospital
Helicobacter Pylori, the Operative Link on Gastric Intestinal Metaplasia
The Influence of Helicobacter Pylori Eradication on Gastric Pathology: a Long-term, Prospective Cohort Study
Helicobacter pylori (H. pylori) infection, affecting an estimated 50% of the global population, is a main cause of chronic gastritis, peptic ulcers and gastric cancer.
- Conditions
- Helicobacter Pylori, the Operative Link on Gastric Intestinal Metaplasia, Operative Link on Gastric Intestinal Assessment
- Trial name
- NCT02933229
- Testing
- biopsy, H. pylori eradication
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shandong University
Bacteremia
A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures
The aim of this study is to evaluate the efficacy of prophylactic dosage with amoxicillin (AMX), amoxicillin-clavulanate (AMX-CLV), and a combination of amoxicillin-clavulanate and a chlorhexidine mouthwash (AMX-CLV-CHX) in the…
- Trial name
- NCT02115776
- Testing
- Amoxicillin-Potassium Clavulanate, Amoxicillin, Chlorhexidine
- Where
- 2 sites in Spain
- Volunteers
- 266 people
- Sponsor
- University of Santiago de Compostela
Tonsillectomy
Effect of Duration of Antibiotic Therapy on Recovery Following Tonsillectomy
To determine whether a 3-day course of postoperative antibiotics is effective as a 7-day course in reducing pain and reducing time to resumption of normal diet and activity following pediatric tonsillectomy
- Trial name
- NCT00662987
- Testing
- 7 days of amoxicillin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infections
Antibiotic Therapy is Not Necessary to Implant Totally Implantable Venous Access Devices: Randomized Prospective Study
BACKGROUND: The growing use of totally implantable venous access devices (TIVAD) has caused the simultaneous increase of various complications.
- Trial name
- TIVAD (NCT00665873)
- Testing
- PORT-A-CATH (Smiths Medical Inc., MN), Amoxicillin and clavulanic acid
- Volunteers
- 100 people
- Sponsor
- University of Catania
Helicobacter Pylori-positive With Functional Dyspepsia
Effect of H. Pylori Eradication on Alleviating Symptoms in Functional Dyspepsia Patients
In patients with Helicobacter pylori-positive functional dyspepsia, long-term follow-up for 6 months after standard triple therapy first-line eradication treatment, the rate of symptom disappearance and degree of improvement of…
- Trial name
- NCT05786807
- Testing
- K-CAB
- Where
- South Korea
- Volunteers
- 315 people
- Sponsor
- Wonkwang University Hospital
Out-of-hospital Cardiac Arrest
Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest
The purpose of this study is to determine whether there is potential benefits of prophylactic antibiotic treatment in comatose survivors of out-of-hospital cardiac arrest (OHCA) treated in intensive care unit with therapeutic…
- Trial name
- NCT02899507
- Testing
- Amoxicillin-Clavulanic acid
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Hypercholesterolemia
Gut Flora and Lipid Metabolism
It is well known that metabolic responses to diet and drugs are affected by genetic and environmental factors. Still, a large part of differences in responses between individuals remains unexplained.
- Trial name
- NCT01566266
- Testing
- Amoxicillin
- Where
- Netherlands
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Liver Transplant, Carbapenem-resistant Enterobacterales
Targeted Versus Standard Peri-operative Antibiotic Prophylaxis in Patients Colonized With Carbapenemase Producing Enterobacterales Undergoing Liver Transplantation
This is a multicenter stepped-wedge cluster randomized trial, conducted over a 2-year period at three hospitals. The trial is structured into four phases, each lasting six months.
- Conditions
- Liver Transplant, Carbapenem-resistant Enterobacterales, CRE Colonization
- Trial name
- TAILOR (NCT07759453)
- Testing
- Ceftazidime - Avibactam ( CAZ-AVI), Meropenem-Vaborbactam, Imipenem+Relebactam
- Where
- 3 sites in Italy
- Volunteers
- 168 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Helicobacter Pylori Infection
Comparing the Efficacy of 14-day Reverse Hybrid Therapy and 14-day Triple Therapy Plus Bismuth Therapy
Reverse hybrid therapy achieves a higher eradication rate than bismuth (triple therapy plus bismuth) remains unanswered
- Trial name
- NCT03321773
- Testing
- triple therapy plus bismuth therapy, reverse hybrid therapy
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Preterm Premature Rupture of Membranes (PPROM)
Treatment of ppROM With Erythromycin vs. Azithromycin Trial
Preterm premature rupture of membranes (PPROM) complicates 4% of pregnancies annually. This pregnancy complication is a major contributor to preterm births and results in neonatal morbidity and mortality.
- Trial name
- TREAT (NCT03060473)
- Testing
- Azithromycin, Erythromycin, Ampicillin
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Bariatric Surgery Candidate
Effect of Stomach Reduction Surgery on the Parameters of Amoxicillin
The objective of this study was to evaluate the impact of bariatric surgery on the pharmacokinetics of amoxicillin. Methods: This study was performed as a randomized, open-label, single-dose clinical trial, with two periods of…
- Trial name
- NCT03588273
- Testing
- Amoxil 500 MG Oral Capsule
- Where
- Brazil
- Volunteers
- 8 people
- Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Paediatric Antimicrobial Pharmacokinetics
Neonatal and Paediatric Pharmacokinetics of Antimicrobials Study
The aim of NAPPA is to develop new models to improve our understanding of how children process ('metabolise') penicillins, to help us discover if we can improve the dosing regimens used for children in the future.
- Trial name
- NAPPA (NCT01975493)
- Where
- 9 sites in United Kingdom
- Volunteers
- 428 people
- Sponsor
- St George's, University of London
Periodontitis
Control of Periodontal Infections
The purpose of this study is to test combined effects of scaling and root planing with periodontal surgery, systemically administered amoxicillin and metronidazole, and/or local tetracycline on pocket depth reduction and…
- Trial name
- NCT01098448
- Testing
- scaling and root planing, local tetracycline, systemic metronidazole and amoxicillin
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- The Forsyth Institute
Protracted Bacterial Bronchitis
Antibiotics, Microbiology and Immunology in Children With Chronic Wet Cough - the AMIC Study
The AMIC study is a double-blind, placebo-controlled, multicenter, nationwide, randomized controlled academic pharmaceutical trial.
- Trial name
- AMIC (NCT06020716)
- Testing
- Amoxicillin-Clavulanate 400 Mg-57 Mg/5 mL Oral Powder for Reconstitution
- Where
- 7 sites in Norway
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Periodontitis, Periodontal Diseases
Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice
Periodontitis is a bacterial inflammatory disease and antibiotic use is being empirically used as part of its treatment. However, a clinical practice guideline on periodontal treatment adjuncts published in 2015 identified weak…
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket
- Trial name
- PAAS (NCT06131021)
- Testing
- Amoxicillin, Metronidazole
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pancreatic Fistula
eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF
The purpose of this clinical trial is to investigate if prolonged antibiotics after pancreatoduodenectomy can prevent the development of a pancreatic fistula and related complications.
- Trial name
- NCT05753735
- Testing
- Piperacillin/Tazobactam, Amoxicillin/ Clavulanic acid
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Case Comprehensive Cancer Center
Obesity
Pharmacokinetic Study of the Association of Amoxicillin / Clavulanic Acid to Obese Adults
Description of the pharmacokinetic parameters of the amoxicillin / clavulanic acid to healthy voluntary obese after oral and intra venous administration Determination of the pharmacokinetic parameters of amoxicillin / clavulanic…
- Trial name
- PHACO (NCT02571959)
- Testing
- amoxicillin and clavulanic acid
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Acute Exacerbation Copd
Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD
This study assess whether a procalcitonin guided antibiotic therapy can reduce significantly unnecessary antibiotic prescription during severe exacerbation of COPD requiring mechanical ventilation without compromising patients'…
- Trial name
- NCT03440060
- Testing
- procalcitonin
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- University Hospital, Mahdia
H. Pylori Infection
Optimization of Keverprazan-amoxicilli Dual Therapy for Helicobacter Pylori
The purpose of this study was to evaluate the efficacy and safety of keverprazan with different doses of amoxicillin for Helicobacter Pylori.
- Trial name
- NCT06412640
- Testing
- Keverprazan, Amoxicillin
- Volunteers
- 268 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University