Clinical trials: enrolling by invitation
Normal Physiology, Alcohol Use Disorder
Addictions Neuroclinical Assessment (ANA)
Background: Alcohol use disorder (AUD) is a major public health problem. In the U.S., 16 to 18 million adults have an AUD. Researchers want to test an assessment tool called the ANA.
- Trial name
- NCT04946851
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Neuroendocrine Tumors
Liver Transplantation Versus Conventional Medical Therapy for Low-Grade GEP-NET With Liver Metastases
Liver Transplantation Versus Conventional Medical Therapy for Low-Grade GEP-NET With Liver Metastases
- Trial name
- TRANET-GEP (NCT07913113)
- Testing
- Liver Transplantation
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chiyi Chen
Nitrate, Placebo - Control
Beetroot Juice and Neuromuscular Performance in Female Basketball Players
A randomized, double-blind, placebo-controlled study investigates the effects of 5 days of nitrate-rich beetroot juice supplementation (70 mL·day-¹; 6.4 mmol NO₃-·day-¹) on physical performance in female basketball players.
- Trial name
- BASKET_BEET (NCT07833579)
- Testing
- Beetroot juice supplementation
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Hypertension, Vascular Disease
Real-World Validation of A Minimally Disruptive Ambulatory Blood Pressure Monitoring (ABPM) Huawei Smartwatch in Malaysia
Background: Ambulatory Blood Pressure Monitoring (ABPM) is the gold standard for diagnosing high blood pressure (hypertension) because it tracks blood pressure continuously across day and night.
- Conditions
- Hypertension, Vascular Disease, Cardiovascular (CV) Risk, Cardiovascular Disease
- Trial name
- Huawei-SunU02 (NCT07913607)
- Where
- Malaysia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sunway University
Neoplasms, Cancer
Data Collection, Clinical Care and Interventions in CCR, NCI
This study provides cancer care through the National Cancer Institute's Medical Oncology Branch (MOB) to patients who are not enrolled in an active treatment research protocol.
- Trial name
- NCT00923065
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Genetic Predisposition to Cancer
Breast Cancer Risk Assessment and Management Program
The objective of this project is to assess the implementation of evidence-based, digital tools to improve breast cancer risk assessment and related primary cancer prevention services for those at high risk for developing breast…
- Trial name
- RAMP-BC (NCT07911592)
- Testing
- Patient nudge via text message, Patient nudge via phone call
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Urolithiasis, Intrarenal Pressure
Renal Structural and Functional Alterations Following Repeated Ureteroscopic Procedures: An Exploratory Multimodal Imaging Study
Introduction and objectives Saline irrigation and instrumentation during Retrograde Intrarenal Surgery (RIRS) causes elevation of intrarenal pressure (IRP) inducing intrarenal backflow (IRB).
- Conditions
- Urolithiasis, Intrarenal Pressure, MRI Scans, Scintigraphy Quantification
- Trial name
- BackFlow2 (NCT07913178)
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Region of Southern Denmark
Longevity, Preventive Medicine
Tirzepatide and Organ-specific Biological Aging
The purpose of this study is to evaluate blood-based measures of organ-specific biological age, with a particular focus on the brain, and to investigate their relationship with established clinical indicators of health and their…
- Conditions
- Longevity, Preventive Medicine, Biological Ageing
- Trial name
- NCT07906041
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Atria Research and Global Health Institute (ARGHI)
Mental Health, Psychological Wellbeing
This Study Tests the Development and Efficacy of a Kindness Focused Intervention on University Students in Islamabad. It Aims to See the Impact of This Intervention on the Psychosocial Well-being of These Emerging Adults.
The primary purpose of this study is to evaluate the development and efficacy of an evidence-based kindness intervention. By focusing on university students in Islamabad, this research aims to determine whether a positive…
- Conditions
- Mental Health, Psychological Wellbeing, Social Wellbeing, Psychosocial Well-being
- Trial name
- KFT (NCT07911189)
- Testing
- therapy
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University of Modern Languages
Pearson Syndrome, Mitochondria DNA Deletion
Investigation of the Treatment of Patients With Mitochondrial Defects by Assisted Reproductive Technology
Mitochondria are important organelles that generate energy (ATP) in human and mammalian cells. Currently, there are more than 50 kinds of diseases known to be related to mitochondrial defects in Taiwan.
- Trial name
- NCT07911306
- Testing
- Maternal spindle transfer
- Where
- Taiwan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Taipei Fertility Center
Nurse, Burnout, Healthcare Workers
Adaptation and Evaluation of RESTORE
The purpose of this clinical trial is to test whether the RESTORE intervention works to reduce nurse burnout, by engaging nursing staff in system redesign to reduce job demands and increase job resources.
- Trial name
- NCT07104474
- Testing
- RESTORE
- Where
- United States
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Rosacea, Vascular Diseases
Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions
This is a clinical study to evaluate the safety and performance of the Vbeam Pro Laser System for the treatment of vascular indications, including rosacea and port wine stain birthmarks.
- Conditions
- Rosacea, Vascular Diseases, Port-Wine Stain
- Trial name
- NCT07290426
- Testing
- Vbeam Pro Laser Treatment
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Traumatic Brain Injury
Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials
Patients evaluated at Penn Presbyterian Medical Center for traumatic brain injury (TBI), who sign the informed consent, will undergo assessment of electrophysiologic potentials evoked by transcranial magnetic stimulation (TMS)…
- Trial name
- (TMS-EEG) (NCT06963775)
- Testing
- Delphi-MD device (QuantalX Neuroscience Ltd., Saba Israel)
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Ramon Diaz-Arrastia
Sedentary Behavior
Recreational Badminton, Sleep and Melatonin
Poor sleep quality is increasingly prevalent among physically inactive young adults and is associated with adverse physical and mental health outcomes.
- Trial name
- NCT07906184
- Testing
- Recreational Badminton, To be used for comparison purposes. There is no intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Inonu University
Trauma, Brain
Risk Assessment of Mild Traumatic Brain Injury in Military Training
The SNIPER-TBI study aims to identify and quantify the risk of mild traumatic brain injury (mTBI) in soldiers of the Czech Armed Forces during specific high-risk training activities, including parachute jumps, high-caliber…
- Trial name
- NCT06992570
- Testing
- Quantification of mild trauma brain injury risk, Biomechanical Analysis of Head Impact Forces
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Skin Cancer Prevention, Sun Safety
Regional Efforts to Advance School-based Sun Safety Through Collaboration for Skin Health
This project will deliver a sun safety education presentation to high schools in the mountain west (e.g., Montana, Wyoming, and Idaho) who are at high melanoma risk.
- Trial name
- REACH West (NCT07904572)
- Testing
- REACH West
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Utah
Lysosomal Storage Disorders, Gaucher Disease
Genetic Studies of Lysosomal Storage Disorders
The purpose of this study is to identify genetic, biochemical, and clinical factors that are associated with disease severity in people with Gaucher disease and other lysosomal storage disorders.
- Conditions
- Lysosomal Storage Disorders, Gaucher Disease, Parkinson Disease
- Trial name
- NCT00001215
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Cancer, Solid Tumors
Collection of Pharmacokinetic Samples From People With Unanticipated Response, Significant Toxicity or Concern of Future Toxicity
Background: Certain drugs - even when they are meant to help people - cause side effects. These are unwanted effects of the drug. There are many reasons why a drug might cause side effects in one person and not in another.
- Conditions
- Cancer, Solid Tumors, Neoplasm
- Trial name
- NCT02154022
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer, Breast Cyst
Advanced Ultrasound Signal Processing of Suspicious Breast Images
This study aims to investigate recent developments in ultrasound signal processing to determine if these new techniques can enhance the visibility of important features of interest in breast ultrasound images.
- Conditions
- Breast Cancer, Breast Cyst, Microcalcification
- Trial name
- AUSPICIOUS (NCT07206888)
- Testing
- Imaging
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Health Equity, Cardiovascular Diseases
Techquity by FAITH!
The goal of this clinical trial is to engage African-American churches via an established community-academic partnership (FAITH! Program) to build capacity to promote cardiovascular health and digital health equity in…
- Trial name
- NCT06187077
- Testing
- DHA-Enhanced FAITH! App, FAITH! App
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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