Clinical trials: sponsored by Icahn School of Medicine at Mount Sinai
Healthy Control
Metabolism of Bioactive Dietary Polyphenol Preparation (BDPP)
This study will characterize the clinical pharmacology of a select bioactive polyphenol-rich preparation (Bioactive Dietary Polyphenol Preparation, BDPP) comprised of a select Concord grape juice (CGJ), a select grape seed…
- Trial name
- NCT04421079
- Testing
- Trans-resveratrol, Concord grape juice, Grape seed polyphenol extract
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Crohn Disease, Pregnancy
Modulating Early Life Microbiome Through Dietary Intervention in Crohn's Disease
The MELODY Trial: Modulating Early Life Microbiome through Dietary Intervention in Crohn's Disease, will test whether a non-invasive dietary intervention during pregnancy can improve the gut microbiota composition in both…
- Trial name
- NCT03850600
- Testing
- Diet-CD
- Where
- 2 sites in United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Craniosynostosis
Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull Bones
Craniosynostosis (CS) is a common malformation occurring in ~4 per 10,000 live births in which the sutures between skull bones close too early, causing long-term problems with brain and skull growth.
- Trial name
- NCT03025763
- Testing
- Craniosynostosis Network Environmental Survey, 2D/3D Photography, Buccal Swab Cell Sampling
- Where
- 20 sites in United States, France and 3 more
- Volunteers
- 2,145 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Breast Cancer
Increasing African Immigrant Women's Participation in Breast Cancer Screening
New York City (NYC) is home to a large and diverse immigrant population. Many of these groups face significant barriers to preventive health care, including lack of insurance, poor health care access and language difficulties.
- Trial name
- AIBCS (NCT04450264)
- Testing
- African Immigrant Breast Cancer Education Program
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Frailty
SCM Muscle as a Marker for Frailty in Patients Undergoing ENT Surgery
This study focuses on evaluating the relationship between physical frailty and measurements of the muscles of the neck in patients undergoing non-cancer Head and Neck surgery.
- Trial name
- NCT06704256
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hyperlipidemia, Pregnancy
Lipid Profile as Predictor of Adverse Maternal and Neonatal Outcomes: A Pilot Study
The purpose of this study is to ascertain lipid profiles during pregnancy, specifically during the 24-28 week gestation and again near term at 36 weeks gestation.
- Trial name
- NCT05535660
- Testing
- Lipid panel
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hysterotomy
Barbed Suture for Hysterotomy Closure During Cesarean Section
This is a randomized controlled trial. The purpose of this study is to see if patients whose uterine incision (hysterotomy), at the time of scheduled cesarean section, is closed with barbed suture, have less blood loss compared…
- Trial name
- NCT04622267
- Testing
- Barbed suture, Standard antimicrobial suture
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obesity
Multi-level Supermarket Discount Study
The study team's objective is to test the effect of supermarket discount levels on fruit and vegetable (F\&V) and non-caloric beverage purchasing and consumption, as well as health outcomes.
- Trial name
- NCT04178824
- Testing
- Discount Intervention
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Major Depressive Disorder
Real-time Biofeedback With 7-Tesla MRI for Treatment of Depression
Previous research has shown that modulation of a brain region in rodents, the ventral tegmental area (VTA), improves depressive symptoms.
- Trial name
- Biofeedback (NCT04138680)
- Testing
- Active Biofeedback
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ptosis, Macular Degeneration
Comparing Vision Tests in a Virtual Reality Headset to Existing Analogues
The purpose of this study is to compare the results of vision tests that are algorithmically derived and delivered through a virtual reality headset with those delivered through the existing technology standards (eg.
- Conditions
- Ptosis, Macular Degeneration, Ametropia
- Trial name
- RTS1 (NCT04714424)
- Testing
- Virtual Reality Headset
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ophthalmology, Vision Screening
Community Interest in Vision Screening Technology
Virtual reality (VR) is a relatively new, emerging field within healthcare. Studies have analyzed public perceptions of virtual reality in healthcare using social media, but few have actually demonstrated and educated these…
- Trial name
- RTS2 (NCT04980430)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post-operative Milestones
Abdominal Binder and Steps Trial
Large lower abdominal incisions are still used in many types of common gynecologic surgeries. Patients may experience pain and restrictions to ambulation because of this, which can make healing after surgery harder and more…
- Trial name
- ABS (NCT04414384)
- Testing
- Abdominal Binder, Step Counter
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colorectal Cancer
e-Motivación: Developing and Pilot Testing an App to Improve Latinos' Screening Colonoscopy Rates
Among Latinos, a fast growing and underserved population, Colorectal Cancer (CRC) is the third leading cause of cancer death in men and in women.
- Trial name
- NCT04987788
- Testing
- Motívate, Video link
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Screening Mammogram
Increasing Breast Cancer Screening in Chinese Immigrants
The long-term goal of this research is to increase breast cancer screening rates in NYC Chinese immigrants. The researchers plan to accomplish this objective by developing and testing a culturally- and linguistically-adapted…
- Trial name
- NCT05089292
- Testing
- Narrative breast health education
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Labor Induction
Foley Catheter Induction
The foley catheter (single lumen balloon) is one of the most cost effective, readily available methods for cervical ripening to begin an induction of labor.
- Trial name
- NCT05257187
- Testing
- Transcervical foley catheter
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Portal Hypertension, Clinically Significant Portal Hypertension
Assessment of Portal Hypertension With Multiparametric MRI
The purpose of this study is to determine whether new multiparametric magnetic resonance imaging (MRI) methods (including diffusion-weighted MRI, dynamic contrast-enhanced MRI, MR elastography and phase-contrast imaging) can be…
- Trial name
- NCT03436550
- Testing
- mpMRI, ARFI US
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Preterm Birth
NICU-HEALTH (Hospital Exposures and Long-Term Health)
The purpose of this study is to evaluate the impact of environmental exposures during the NICU hospitalization on preterm infant development. The research team is interested in both chemical and non-chemical exposures.
- Trial name
- NCT01963065
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Stroke, Cerebral Palsy
Gondola Mechanism of Action
This study will investigate the clinical, functional and neurophysiological effects of automated mechanical peripheral stimulation (AMPS) via the Gondola device administered to patients with chronic stroke, cerebral palsy and…
- Conditions
- Chronic Stroke, Cerebral Palsy, Parkinson's Disease
- Trial name
- NCT05146648
- Testing
- Gondola AMPS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Shivering, Labor
Investigating the Effect of Acupressure on Shivering During a Cesarean Delivery in Women Who Were Previously Laboring With an Epidural
Shivering during a cesarean section can be quite uncomfortable for the patient as well as make it difficult for the anesthesiologist to obtain vital signs.
- Conditions
- Shivering, Labor, Cesarean Delivery
- Trial name
- NCT03497507
- Testing
- Acupressure bracelet
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Contraception
Music as a Nonpharmacologic Approach to Pain Control With Intrauterine Device Placement
The intervention of this study is the addition of patient-selected music during IUD insertion procedure. Subjects randomized to the music group will choose 10 songs, which will be played during the procedure, from the time of…
- Trial name
- NCT04835701
- Testing
- Music
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai