Clinical trials: active, in Yemen
Partial Edentulism Class 3, Removable Partial Denture
Clinical Fit of Conventionally Cast and 0° SLM Removable Partial Denture Frameworks
This exploratory pilot clinical study evaluates the fit accuracy of cobalt-chromium removable partial denture (RPD) frameworks fabricated using conventional lost-wax casting and selective laser melting (SLM) at a 0° build…
- Trial name
- NCT07863427
- Testing
- Conventionally Cast Cobalt-Chromium RPD Framework, 0° Selective Laser-Melted Cobalt-Chromium RPD Framework
- Where
- Yemen
- Volunteers
- 2 people
- Sponsor
- IBB University
Thin Gingival Phenotype
Injectable Platelet-Rich Fibrin and Microneedling With or Without Vitamin C for Gingival Phenotype Augmentation.
This randomized split-mouth clinical trial will evaluate whether adding locally injected vitamin C to injectable platelet-rich fibrin (i-PRF) and microneedling improves gingival tissue thickness and keratinized tissue width in…
- Trial name
- NCT07848035
- Testing
- Microneedling, Injectable Platelet-Rich Fibrin (i-PRF), Vitamin C
- Where
- Yemen
- Volunteers
- 27 people
- Sponsor
- University of Science and Technology, Yemen
Facial Injuries, Pain
Topical Dexamethasone/Diclofenac Hydrogel for Postoperative Pain and Swelling in Facial Soft Tissue Injuries
This randomized, controlled clinical trial will evaluate the clinical effects of a topical thermoresponsive hydrogel containing dexamethasone sodium phosphate and diclofenac sodium on postoperative pain and facial swelling in…
- Conditions
- Facial Injuries, Pain, Swelling
- Trial name
- NCT07853664
- Testing
- Poloxmer F-127 Hydrogel with Dexamethasone/Diclofenac
- Where
- Yemen
- Volunteers
- 52 people
- Sponsor
- Thamar University
Cross Bite
Evaluation of Myobrace for Crossbite Correction in Mixed Dentition
This randomized controlled clinical trial will evaluate the effectiveness of the Myobrace appliance in correcting anterior and posterior crossbite in children aged 6 to 10 years during the mixed dentition stage.
- Trial name
- Myo vs Frankel (NCT07840053)
- Testing
- Myobrace Interceptive Class III Appliance, Frankel III Functional Regulator
- Where
- Yemen
- Volunteers
- 40 people
- Sponsor
- Sana'a University
Partial Edentulism, Dental Implant Placement
Effect of Advanced PRF and Hyaluronic Acid on Dental Implant Healing
This randomized parallel-group clinical trial aimed to evaluate the clinical efficacy of advanced platelet-rich fibrin (A-PRF) combined with hyaluronic acid (HA) in enhancing peri-implant bone formation in patients undergoing…
- Trial name
- NCT07792720
- Testing
- Delayed Dental Implant Placement, Advanced Platelet-Rich Fibrin (A-PRF), Hyaluronic Acid 1.5%
- Where
- Yemen
- Volunteers
- 30 people
- Sponsor
- Samar Ali Abdu Salamah
Orthodontic Tooth Movement
Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners
This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement.
- Trial name
- NCT07795073
- Testing
- Platelet Rich Plasma (PRP) injection, photobiomodulation (PBM) Therapy, clear aligner(12-hour wear protocol)
- Where
- Yemen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Color Stability of Dental Ceramics, Zirconia Restorations
Impact of Khat Chewing on Color Stability and Patient Satisfaction of Multilayer Zirconia and Feldspathic Veneer Zirconia.
This study aims to evaluate and compare the impact of khat chewing on the color stability and patient satisfaction of multilayer zirconia and feldspathic veneered zirconia restorations.
- Conditions
- Color Stability of Dental Ceramics, Zirconia Restorations, Khat Chewing Effects, Dental Restoration Staining
- Trial name
- NCT07786272
- Testing
- Multilayer Zirconia Crowns, Feldspathic Veneered Zirconia Crowns
- Where
- Yemen
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Thamar University
Osseodensification, Bone Expansion
Osseodensification for Narrow Alveolar Ridge Expansion
This prospective, single-arm, non-randomized interventional clinical study was designed to evaluate the immediate horizontal dimensional change in narrow alveolar ridges following osseodensification-assisted dental implant-site…
- Conditions
- Osseodensification, Bone Expansion, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- OD-RridgeExp (NCT07436533)
- Testing
- Densah burs (Osseodensification Technique)
- Where
- Yemen
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Cleft Palate, Unilateral Cleft Palate
Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate
This prospective, randomized controlled trial evaluates the clinical efficacy of autologous Platelet-Rich Fibrin (PRF) and Gentamicin-Loaded PRF as regenerative and antimicrobial biological adjuncts in primary palatoplasty.
- Conditions
- Cleft Palate, Unilateral Cleft Palate, Bilateral Cleft Palate, Complete Cleft Palat
- Trial name
- NCT07752849
- Testing
- Standard palatoplasty ( control), Platelet _ Rich Fibrin ( PRF), gentamicin_ loaded PRF
- Where
- Yemen
- Volunteers
- 90 people
- Sponsor
- Al-Thawra Modern General Hospital
Appendicitis, Surgical Wound Infection
Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)
The goal of this clinical trial is to compare primary wound closure (PC) versus delayed primary closure (DPC) after standardized wound decontamination using the High-Efficiency Incision and Drainage with Irrigation (HIEDI)…
- Conditions
- Appendicitis, Surgical Wound Infection, Postoperative Complications, Wound Healing
- Trial name
- HIEDI-Yemen (NCT07688109)
- Testing
- Primary Closure with HIEDI, Delayed Primary Closure with HIEDI
- Where
- 3 sites in Yemen
- Volunteers
- 200 people
- Sponsor
- Sana'a University
Hemorrhoids, Postoperative Pain
Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy
The goal of this clinical trial is to evaluate whether oral nifedipine reduces postoperative pain and improves wound healing after hemorrhoidectomy in adult patients aged 18-65 years undergoing elective surgery for grade III or…
- Conditions
- Hemorrhoids, Postoperative Pain, Wound Healing, Analgesia
- Trial name
- NIFEDIPINE-HD (NCT07659665)
- Testing
- Nifedipine 20 Mg
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Preeclampsia
Vitamin D3 Supplementation Regimens and Preeclampsia Risk
This study is a randomized controlled trial with two parallel groups connected at Al-Thawra Modern General Hospital in Sana'a, Yemen.
- Trial name
- VitD-PE-RCT (NCT07648706)
- Testing
- Vitamin D3
- Where
- Yemen
- Volunteers
- 268 people
- Sponsor
- Sana'a University
Kidney Calculi, Nephrolithiasis
Supine vs. Prone PCNL for Large Renal Stones: A Randomized Trial in Yemen.
The goal of this clinical trial is to compare the safety, cost-effectiveness, and patient recovery of two different surgical positions for percutaneous nephrolithotomy (PCNL) in adults aged 18 to 70 years who have kidney stones…
- Trial name
- NCT07627503
- Testing
- Supine Percutaneous Nephrolithotomy (PCNL), Prone Percutaneous Nephrolithotomy (PCNL)
- Where
- Yemen
- Volunteers
- 140 people
- Sponsor
- Sana'a University
Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization
Graftless TSFE Via Self-tapping Implants
This prospective clinical trial aims to evaluate the efficiency, safety, and reliability of a minimally invasive graftless transcrestal sinus lifting approach with simultaneous dental implant placement in patients with edentulous…
- Conditions
- Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- G-TSFE (NCT07424742)
- Testing
- Graftless Transcrestal Sinus Membrane Elevation with Simultaneous Implant Placement
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Infertility Drugs, Infertility Involuntary
Letrozole vs. Clomiphene Citrate Plus Tamoxifen for Ovulation Induction and Pregnancy Outcomes.
Infertility is a common reproductive health problem. Ovulation induction is a key treatment for women with anovulatory infertility. Letrozole and clomiphene citrate are widely used medications for ovulation induction.
- Trial name
- LET-CC-TAM (NCT07616973)
- Testing
- Letrozole, Clomiphene Citrate + Tamoxifen
- Where
- Yemen
- Volunteers
- 240 people
- Sponsor
- Sana'a University
Skeletal Class II Malocclusion
"Sliding Jigs vs Retraction Hooks for Maxillary Dentition Distalization Using IZC Miniscrews"
This randomized controlled clinical trial aims to compare the clinical efficacy, efficiency, and biomechanical differences between two methods for total maxillary dentition distalization: (1) the use of a Sliding Jig and (2) the…
- Trial name
- SJRH-IZC (NCT07307209)
- Testing
- Sliding jig, retraction hooks
- Where
- Yemen
- Volunteers
- 40 people
- Sponsor
- Sana'a University
Periodontal Disease
Efficacy of Laser Therapy for Periodontitis
The aim of this study is to evaluate the efficacy of diode laser in addition to periodontal treatment in periodontitis patients and to investigate their effects on gingival crevicular fluid (GCF) cytokine levels before and after…
- Trial name
- NCT07013162
- Testing
- High power diode laser + SRT, Low diode diode laser + SRT, Curettage (SRT) only
- Where
- 2 sites in Yemen
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Malocclusion; Displaced Teeth
3-D Evaluation of Alveolar Bone Changes and Root Resorption After Traction of Buccally Displaced Maxillary Canines
This clinical study used CBCT images to investigate the alveolar bone changes and root resorption in unilateral buccally displaced maxillary canines and adjacent teeth before and after orthodontic traction of unilateral BDMCs.
- Trial name
- BDMC (NCT07399197)
- Testing
- T-loop, Piggyback double wire
- Where
- Yemen
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Wisdom Tooth Removal, Post Operative Complications
Comparing Methylprednisolone And Hyaluronic Acid To Reduce Wisdom Tooth Surgery Complications
The goal of this clinical trial is to assess and compare the effectiveness of methylprednisolone and hyaluronic acid (HA), alone and in combination, in managing post-operative complications following the surgical extraction of…
- Conditions
- Wisdom Tooth Removal, Post Operative Complications, Hyaluronic Acid, Methylprednisolone
- Trial name
- NCT07317596
- Testing
- Methyl Prednisolone (MP), Hyaluronic Acid (HA)
- Where
- Yemen
- Volunteers
- 40 people
- Sponsor
- Sana'a University
Odontogenic Cyst, Jaw Cysts
Bone Regeneration Using PRF After Cyst Enucleation
This randomized controlled clinical trial aims to evaluate the clinical efficacy of autologous platelet-rich fibrin (PRF) in promoting osseous regeneration following cystic enucleation in the jaws.
- Conditions
- Odontogenic Cyst, Jaw Cysts, Osseous Defect After Cyst Enucleation
- Trial name
- PRF-Bone (NCT07424716)
- Testing
- Autologous Platelet-Rich Fibrin (PRF), Conventional Surgical Management
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University