Clinical trials: in Venezuela
Breast Cancer
Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.
The purpose of this study is to evaluate the efficacy of a new dose of 500 mg Fulvestrant with the standard dose of 250 mg in postmenopausal women with oestrogen receptor positive advanced breast cancer who have failed on a…
- Trial name
- CONFIRM (NCT00099437)
- Testing
- Fulvestrant
- Where
- 106 sites in United States, Belgium and 15 more
- Volunteers
- 736 people
- Sponsor
- AstraZeneca
Persistent Spinal Pain Syndrome Type 2 (PSPS-T) Lower Spine, Chronic Low Back Pain
SPINE-RISK VE: Multimodal Predictive Model for Failed Back Surgery Syndrome in Venezuelan Surgical Patients
SPINE-RISK VE is a prospective multicenter cohort study designed to develop and internally validate a multimodal preoperative predictive model for Failed Back Surgery Syndrome (FBSS), now classified as Persistent Spinal Pain…
- Conditions
- Persistent Spinal Pain Syndrome Type 2 (PSPS-T) Lower Spine, Chronic Low Back Pain, Postoperative Pain, Lumbar Spine Surgery
- Trial name
- SPINE-RISK VE (NCT07693517)
- Testing
- SPINE-RISK VE multimodal preoperative assessment
- Where
- Venezuela
- Volunteers
- 150 people
- Sponsor
- juan jose valero quintero,MD
Post Operative Pain, Acute, Laparoscopic Appendectomy
Intraoperative Intravenous Lidocaine for Pain After Laparoscopic Appendectomy
This randomized, double-blind, placebo-controlled clinical trial evaluated whether intraoperative intravenous lidocaine infusion improves postoperative analgesia and recovery in patients undergoing laparoscopic appendectomy.
- Trial name
- LIDO-APP (NCT07678385)
- Testing
- Lidocaine (drug)
- Where
- Venezuela
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Post Operative Analgesia, Tonsillectomy
Weight-Adjusted Diclofenac Potassium Medicated Lollipop for Post-Adenotonsillectomy Pain in Children
Brief Summary This study aimed to develop and conduct a preliminary clinical evaluation of a novel weight-adjusted gelatin-based diclofenac potassium medicated lollipop for the management of postoperative pain following…
- Conditions
- Post Operative Analgesia, Tonsillectomy, Pediatric Anesthesia
- Trial name
- DICLOPOP (NCT07646093)
- Testing
- Diclofenac Potassium Medicated Lollipop
- Where
- Venezuela
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Postoperative Pain, Tonsillectomy
Ketamine Gargle for Pain After Pediatric Tonsillectomy
Post-tonsillectomy pain in children is a common and clinically significant problem that may lead to poor oral intake, dehydration, and delayed recovery.
- Conditions
- Postoperative Pain, Tonsillectomy, Adenotonsillectomy
- Trial name
- KET-TONSIL (NCT07558044)
- Testing
- Ketamine Hydrochloride in saline, Normal Saline (0.9% NaCl)
- Where
- Venezuela
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Postoperative Pain, Cesarean Section
Intrathecal Morphine 75 mcg Versus 100 mcg for Post-Cesarean Analgesia: A Randomized Double-blind Trial
This study evaluates the efficacy and safety of two different doses of intrathecal morphine (75 mcg versus 100 mcg) for postoperative analgesia in patients undergoing elective cesarean delivery under spinal anesthesia.
- Conditions
- Postoperative Pain, Cesarean Section, Obstetric Anesthesia
- Trial name
- ITM-CESAREAN (NCT07516717)
- Testing
- Intrathecal Morphine
- Where
- Venezuela
- Volunteers
- 240 people
- Sponsor
- Hospital Universitario de Caracas
Masked Hypertension
MASked-unconTrolled hypERtension Management Based on Office BP or on Out-of-office (Ambulatory) BP Measurement
MASTER study is a 4-year prospective, randomized, open-label, blinded-endpoint study (PROBE) comparing 2 management strategies 1) office BP as a guide to treatment, or 2) 24-hour ABP as a guide to treatment.
- Trial name
- MASTER (NCT02804074)
- Testing
- Optimization of antihypertensive treatment based on office BP, Optimization of antihypertensive treatment based on 24-hour ABPM
- Where
- 2 sites in Italy, Venezuela
- Volunteers
- 1,240 people
- Sponsor
- Istituto Auxologico Italiano
Pulpitis - Irreversible, Pulpitis
Vital Pulp Therapy vs. Root Canal Treatment in Mature Teeth With Irreversible Pulpitis
This study was designed as a prospective, randomized, controlled clinical trial with parallel groups and double blinding, following the principles of the Declaration of Helsinki for human experimentation and in accordance with…
- Conditions
- Pulpitis - Irreversible, Pulpitis, Pulpotomy, Root Canal Therapy
- Trial name
- NCT07355140
- Testing
- VPT Group and RCT Group
- Where
- Venezuela
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidad Central de Venezuela
Carpal Tunnel Syndrome
Gabapentin and Neural Mobilization Pain Reduction Effect Compared to Only Gabapentine
In the present investigation the pain reduction effects of a physiotherapy technique combined with pharmaceutical gabapentin treatment will be compared to those produced by gabapentin (only) treatment, in subjects who suffer the…
- Trial name
- NCT06778798
- Testing
- Median nerve neural mobilization and oral gabapentin, Gabapentin 300mg
- Where
- Venezuela
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Carpal Tunnel Syndrome
Ibuprofen Arginine and Neural Mobilization Versus Ibuprofen Arginine in the Treatment of Carpal Tunnel Syndrome
In the present investigation the pain reduction effects of a physiotherapy technique combined with pharmaceutical ibuprofen arginine treatment will be compared to those produced by ibuprofen (only) treatment, in subjects who…
- Trial name
- NCT06778759
- Testing
- median nerve neural mobilization combined with oral ibuprofen arginine, Ibuprofen Arginine
- Where
- Venezuela
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Carpal Tunnel Syndrome, Ibuprofen
Ibuprofen and Neural Mobilization Treatment in Carpal Tunnel Syndrome.
In the present investigation, the pain reduction effect of median nerve neural mobilization and oral ibuprofen treatments will be compared to those produced by the absence of treatment, in subjects who suffer the signs and…
- Conditions
- Carpal Tunnel Syndrome, Ibuprofen, Pain Management, Pain, Chronic
- Trial name
- NCT04328805
- Testing
- ibuprofen tablets, Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 123 people
- Sponsor
- Universidad Europea de Madrid
Carpal Tunnel Syndrome
Pain Reduction Caused by the Combined Treatment of Physiotherapy, Oral Gabapentin and Oral Ibuprofen Arginine.
In the present investigation the pain reduction effects of a physiotherapy technique combined with gabapentin and ibuprofen arginine will be compared to those produced by an ibuprofen arginine (only) treatment, in subjects who…
- Trial name
- NCT06781489
- Testing
- Median nerve neural mobilization, Gabapentin 300mg, Ibuprofen Arginine
- Where
- Venezuela
- Volunteers
- 129 people
- Sponsor
- Universidad Europea de Madrid
Carpal Tunnel Syndrome
Physical Therapy in the Treatment of Carpal Tunnel Syndrome
In the present investigation the pain reduction effects of a physical therapy technique will be compared to those produced by the absence of treatment, in subjects who suffer the signs and symptoms of carpal tunnel syndrome.
- Trial name
- NCT04329247
- Testing
- Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 74 people
- Sponsor
- Universidad Europea de Madrid
Carpal Tunnel Syndrome
Pain Reduction Produced by Different Treatments in Carpal Tunnel Syndrome
Pain reduction effects of the median nerve neural mobilization technique (a physiotherapy treatment) will be compared to those produced by a pharmaceutical treatment and the absence of treatment, in subjects who suffer carpal…
- Trial name
- NCT04119739
- Testing
- Median nerve neural mobilization, Ibuprofen Arginine
- Where
- Venezuela
- Volunteers
- 117 people
- Sponsor
- Francisco Unda Solano
Carpal Tunnel Syndrome
Oral Gabapentin and Median Nerve Mobilization in the Treatment of Carpal Tunnel Syndrome
The present randomized clinical trial will perform a comparison of the pain reduction effects produced by the application of a non invasive and non pharmacological median nerve neural mobilization (physiotherapy treatment), to…
- Trial name
- NCT04285281
- Testing
- Gabapentin oral capsules, Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 126 people
- Sponsor
- Universidad Europea de Madrid
Carpal Tunnel Syndrome
Pain Reduction and Changes in Upper Limb Function Produced by Different Treatments in Carpal Tunnel Syndrome
In the present investigation the pain reduction effects of a physiotherapy technique will be compared to those produced by two different pharmaceutical treatments and also by the absence of treatment, in subjects who suffer the…
- Trial name
- NCT04025203
- Testing
- Median nerve neural mobilization, Ibuprofen Arginine, Gabapentin
- Where
- Venezuela
- Volunteers
- 196 people
- Sponsor
- Francisco Unda Solano
Diminished Ovarian Reserve
In Vitro Oocyte Maturation With Autologous Exosomes in Women
This study is a preliminary, prospective, randomized, controlled clinical trial designed to evaluate the safety and feasibility of supplementing in vitro maturation (IVM) media with autologous exosomes in women with diminished…
- Trial name
- Exosom2025-1 (NCT07249411)
- Testing
- MI oocytes were cultured in conventional IVM medium supplemented with 10 µg of autologous exosomes obtained using the ExoSMarT® exosome filtration system
- Where
- Venezuela
- Volunteers
- 32 people
- Sponsor
- Biotech Fertility C.A.
Long Bone Fractures
Registry of Pediatric Orthopedic Trauma and Health Outcomes in Skeletally Immature Children
International registry to collect prospective treatment and outcomes data on specific, key non-pathological fractures in children with open physes.
- Trial name
- NCT04207892
- Testing
- Conservative (non-surgical) treatment, Surgical treatment
- Where
- 17 sites in United States, Australia and 10 more
- Volunteers
- 1,000 people
- Sponsor
- AO Innovation Translation Center
Limb Fracture, Bone Loss
An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects
Long bone defect (LBD) is defined as a focalized loss of bone tissue in any long bone of the upper or lower extremity. Long bone defects are a complex problem, that may arise as a complication of many different pathologies, such…
- Trial name
- NCT04112992
- Testing
- Any treatment that is used for a defect of any long bone
- Where
- 21 sites in United States, Australia and 12 more
- Volunteers
- 600 people
- Sponsor
- AO Innovation Translation Center
Poor Ovarian Response, Female Infertility of Other Origin
Exosome-Enriched Culture Media to Enhance In Vitro Maturation and Embryo Development in Poor Ovarian Responders Undergoing IVF
Evaluating the Efficacy of Exosome-Enriched Culture Media to Enhance In Vitro Maturation and Embryo Development in Poor Ovarian Responders Undergoing IVF Summary: This is a prospective, randomized controlled trial designed to…
- Conditions
- Poor Ovarian Response, Female Infertility of Other Origin, Oocyte Immaturity
- Trial name
- EXOMAT (NCT07085312)
- Testing
- Exosome-Enriched IVF Culture
- Where
- Venezuela
- Volunteers
- 10 people
- Sponsor
- Fertiaguerrevere