Clinical trials: open to volunteers, in Turkey (Türkiye)
NASH With Fibrosis, MASH With Fibrosis
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with non-cirrhotic NASH/MASH and fibrosis stage 2 or 3 (F2 or F3).
- Trial name
- NCT06215716
- Testing
- Efruxifermin
- Where
- 361 sites in United States, Argentina and 16 more
- Volunteers
- 1,650 people
- Sponsor
- Akero Therapeutics, Inc
Kyphosis Postural Thoracic, Kyphosis
A Comparison of the Effects of Exercise Methods for Adolescent Hyperkyphosis on the Sensorimotor System
This study will compare two home exercise programs for adolescents aged 10-17 years with postural hyperkyphosis: kyphosis-specific Schroth exercises and traditional stretching and strengthening exercises.
- Trial name
- NCT07922369
- Testing
- Kyphosis-Specific Schroth Exercise Program, Conventional Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Istanbul University - Cerrahpasa
Melanoma
Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivo® as Adjuvant Monotherapy in Participants With Melanoma
The purpose of this study is to investigate the pharmacokinetics (PK) similarity of Bmab1700 (an intended nivolumab biosimilar), compared with United States (US)-licensed Opdivo, in participants after complete surgical removal of…
- Trial name
- NCT07476326
- Testing
- Bmab1700, Opdivo
- Where
- 46 sites in Brazil, Chile and 8 more
- Volunteers
- 120 people
- Sponsor
- Biocon Biologics UK PLC
Apical Periodontitis, Endodontic Retreatment
Effects of Different Activation Techniques on Antimicrobial Photodynamic Therapy in Apical Periodontitis
This randomized clinical trial aims to investigate the effects of different intracanal methylene blue agitation techniques used during antimicrobial photodynamic therapy (aPDT) on root canal microbiota, host inflammatory…
- Trial name
- NCT07921277
- Testing
- Control - aPDT Without Additional Activation, Passive Ultrasonic Irrigation (PUI), Standard Needle Irrigation (SNI)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karadeniz Technical University
Parasternal Block
Evaluation of Large Language Models in Parasternal Block Ultrasound Interpretation
This prospective observational study aims to evaluate the accuracy of multimodal large language models (LLMs) in interpreting ultrasound recordings of superficial and deep parasternal intercostal plane blocks.
- Trial name
- NCT07915206
- Testing
- Multimodal Large Language Model-Based Ultrasound Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Sedentary Lifestlye, Exercise
Yoga vs. Stretching-Strengthening: Physical Fitness in Sedentary Young Adults
The goal of this clinical trial is to learn if yoga or stretching-strengthening exercises are more effective in sedentary young adults who are currently healthy but at risk due to inactivity.
- Trial name
- NCT07680712
- Testing
- yoga group, stretching-strengthening group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Alzheimer's Disease(AD), Mild Cognitive Impairment (MCI)
InRAD Observational Study
The goal of this international observational study is to evaluate long-term disease outcomes and treatment safety in people with Alzheimer's disease (PwAD), by collecting real-world data from routine clinical practice across…
- Conditions
- Alzheimer's Disease(AD), Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD), Non-Alzheimer Degenerative Dementia
- Trial name
- InRAD (NCT07213700)
- Testing
- None, this is a non-interventional observational study
- Where
- 23 sites in Australia, Austria and 15 more
- Volunteers
- 50,000 people
- Sponsor
- Stichting International Registry for Alzheimer's Disease and other Dementias Foundation
Myelodysplastic Syndromes
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
The main aim of this study is to find out how well elritercept works in lowering the need for RBC transfusions. Other aims are to learn how well elritercept works in reducing the need for RBC transfusions over longer periods of…
- Trial name
- NCT06499285
- Testing
- Elritercept
- Where
- 182 sites in United States, Australia and 24 more
- Volunteers
- 225 people
- Sponsor
- Takeda
Type 2 Diabetes Mellitus
Comparison of Functional Inspiratory Muscle Training and Combined Exercise Training in Individuals With Type 2 Diabetes
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that may impair exercise capacity, respiratory muscle strength, balance, and quality of life, and increase fatigue.
- Trial name
- NCT07921901
- Testing
- Combined Excerse Training, Functional Inspiratory Muscle Training, Usual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- İrem Çaylak Yetüt
Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Chronic Lymphocytic
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).
The purpose of this study is to assess the safety and tolerability and to confirm the dose of nemtabrutinib in combination with venetoclax in participants with R/R CLL/SLL.
- Conditions
- Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Chronic Lymphocytic, Small-Cell Lymphoma, Lymphoma, Small Lymphocytic
- Trial name
- NCT05947851
- Testing
- Nemtabrutinib, Venetoclax, Rituximab
- Where
- 106 sites in United States, Argentina and 21 more
- Volunteers
- 735 people
- Sponsor
- Merck Sharp & Dohme LLC
Mandala Coloring
Effect of Mandala Coloring on Anxiety, Pain, Vital Signs, and Patient Satisfaction in Patients Undergoing Transurethral Resection of the Prostate
This study aims to investigate the effect of mandala coloring on anxiety, pain, vital signs, and patient satisfaction in patients undergoing transurethral resection of the prostate (TURP).
- Trial name
- NCT07723794
- Testing
- Mandala Coloring
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Obturator Reflex
Femoral and Sciatic Nerve Blocks Added to Obturator Nerve Block for Prevention of Obturator Reflex
This prospective, randomized controlled study aims to evaluate whether adding femoral and sciatic nerve blocks to obturator nerve block improves the prevention of obturator reflex during transurethral resection of bladder tumors…
- Trial name
- NCT07922941
- Testing
- Obturator Nerve Block, Femoral Nerve Block, Sciatic Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Tuna Erturk
Preoperative Fasting, Pulmonary Aspiration During Anesthetic Induction
Preoperative Gastric Ultrasound and Anaesthetic Management in Patients Undergoing Coronary Artery Bypass Grafting
Fasting before surgery does not always ensure that the stomach is empty. Residual gastric contents may be relevant to the risk of stomach contents entering the lungs during anaesthesia.
- Conditions
- Preoperative Fasting, Pulmonary Aspiration During Anesthetic Induction, Coronary Artery Disease
- Trial name
- NCT07922395
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Istanbul University - Cerrahpasa
Myelofibrosis, Anemia
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
The main aim of this study is to find out how well elritercept works to improve anemia in participants with myelofibrosis (MF) who are taking ruxolitinib when compared to placebo.
- Trial name
- ELRISE MF (NCT07623161)
- Testing
- Elritercept
- Where
- 214 sites in United States, Argentina and 29 more
- Volunteers
- 324 people
- Sponsor
- Takeda
Myelodysplastic Syndrome, Anemia
A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Lower Risk Myelodysplastic Syndromes (LR-MDS) Who Need Regular Blood Transfusions
The main aim of this study is to assess how much elritercept reduces the need for RBC (red blood cell) transfusions and improves hemoglobin blood values in addition to how safe elritercept is when compared with epoetin alfa.
- Trial name
- ELRiSE MDS (NCT07422480)
- Testing
- Elritercept, Epoetin Alfa
- Where
- 166 sites in United States, Argentina and 26 more
- Volunteers
- 300 people
- Sponsor
- Takeda
Cerebral Palsy
Turkish Translation, Cross-Cultural Adaptation, Validity, and Reliability of the ABILHAND-Kids Young CP Scale
The purpose of this study is to perform the Turkish translation, cross-cultural adaptation, validity, and reliability of the ABILHAND-Kids Young CP scale.
- Trial name
- ABILHAND-KYCTR (NCT07894926)
- Testing
- ABILHAND-Kids Young CP Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Calcaneal Spur
Effectiveness of Pulsed Electromagnetic Field Therapy in Patients With Symptomatic Plantar Calcaneal Spurs
This prospective, randomized, sham-controlled clinical trial aims to evaluate the effectiveness of pulsed electromagnetic field (PEMF) therapy in patients with symptomatic plantar calcaneal spurs.
- Trial name
- NCT07919600
- Testing
- Active Pulsed Electromagnetic Field Therapy (PEMF)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Hatice Zehra FERHATLAR
Triple-Negative Breast Cancer
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
This is a randomized, open-label study comparing the efficacy and safety of adjuvant sacituzumab tirumotecan (MK-2870) in combination with pembrolizumab compared to treatment of physician's choice (TPC) in participants with…
- Trial name
- NCT06393374
- Testing
- Pembrolizumab, Sacituzumab tirumotecan, Capecitabine
- Where
- 314 sites in United States, Argentina and 29 more
- Volunteers
- 1,530 people
- Sponsor
- Merck Sharp & Dohme LLC
Lymphedema, Lymphedema Arm
Comparison of the Effects of Kinesio Taping and Compression Bandaging on Edema, Range of Motion, Upper Extremity Function, and Grip Strength in Patients With Breast Cancer-Related Lymphedema
This randomized crossover clinical trial aims to compare the effects of Kinesio Taping and compression bandaging on upper extremity edema, shoulder range of motion, upper extremity function, pain, and grip strength in patients…
- Conditions
- Lymphedema, Lymphedema Arm, Mastectomy
- Trial name
- NCT07919093
- Testing
- lymphedema treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Halic University
Human Papillomavirus Infection
Lived Experiences of Women Diagnosed With HPV Infection
This qualitative phenomenological study aims to explore the lived experiences of women diagnosed with human papillomavirus (HPV) infection.
- Trial name
- NCT07920666
- Testing
- Semi-Structured Interview
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
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