Clinical trials: open to volunteers, in Syria
Periodontitis
Diode Laser 635 nm and 810 nm Photodynamic Therapy as Adjuncts to Non-Surgical Periodontal Treatment
This study aims to evaluate and compare the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) using toluidine blue O (TBO) activated by two different diode laser wavelengths as an adjunct to non-surgical…
- Trial name
- NCT07849647
- Testing
- 635 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, 810 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, Non-Surgical Periodontal Treatment Alone (Control)
- Where
- Syria
- Volunteers
- 12 people
- Sponsor
- Damascus University
Tooth Mobility, Injectable Platelet-rich Fibrin
Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement
One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which…
- Trial name
- NCT06302296
- Testing
- injectable form of PRF
- Where
- Syria
- Volunteers
- 14 people
- Sponsor
- Hama University
Crowding of Anterior Mandibular Teeth
Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will…
- Trial name
- NCT05492773
- Testing
- Micro-osteoperforations Technique, Active comparater
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hama University
Malocclusion, Class II Malocclusion
Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy
Patient with class ii division 1 malocclusion who have mild increased overjet will be treated in this study. The efficacy of clear aligners in the treatment of Class II division 1 Malocclusion Using Intermaxillary Elastics will…
- Trial name
- malocclusion (NCT05684510)
- Testing
- clear aligners, traditional treatment Fixed appliances with class II elastics.
- Where
- Syria
- Volunteers
- 24 people
- Sponsor
- Hama University
Malocclusion, Angle Class II
Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates
Patients with skeletal class II malocclusion who have a retracted lower jaw will be treated in this study. The efficacy of clear Plates in the treatment of Skeletal Class II Malocclusion will be assessed.
- Trial name
- NCT05950581
- Testing
- Modified Twin-Block Appliance with Clear Plates., Traditional Twin-Block appliance
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Hama University
Bone Marrow, Femoral Neck Fractures
Bone Marrow Injection in Fracture of Femoral Neck
Objectives: Primary objective : To investigate the predisposing factors for femoral neck fractures, including age, sex, and associated comorbidities.
- Trial name
- NCT07808294
- Testing
- Anatomical reduction and fixation with bone marrow injection, Anatomical reduction with Fixation
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Yaser Alkanash
Crowns, Tooth Preparation
Clinical Outcomes of Biologically Oriented Preparation Technique
This study aims to evaluate the periodontal response of teeth prepared with a biologically oriented preparation technique (BOPT) compared to conventional preparation for all-ceramic crowns.
- Trial name
- NCT06496828
- Testing
- Biologically-oriented preparation technique, Conventional method of preparation
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Maxillary Deficiency, Bone Resorption
Using Chin Bone Rings for Sinus Lifting and Dental Implants in One Surgery
This study evaluates the Bone Ring Technique, a single stage procedure that combines external sinus floor elevation and dental implant placement using an autogenous bone ring harvested from the chin.
- Trial name
- BRT-SINUS (NCT07619846)
- Testing
- Bone Ring Technique (BRT)
- Where
- Syria
- Volunteers
- 10 people
- Sponsor
- Damascus University
Heart Surgery, Ischemic Heart Disease
Efficacy of Carbohydrate Loading in Diabetic Type 2 Patients Undergoing CABG Surgery on CPB
Enhanced recovery after surgery protocols aim to optimize perioperative care and improve surgical outcomes. Preoperative carbohydrate loading has demonstrated benefits in reducing insulin resistance and improving patient…
- Trial name
- CLDM-CABG (NCT06951308)
- Testing
- Carbohydrate loading before surgery
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Mouth Neoplasms
Tissue Adhesive Versus Sutures in Oral Biopsy Closure
Excisional biopsies are commonly performed in the oral mucosa, and proper wound closure and hemostasis are critical for the success of the surgical procedure.
- Trial name
- NCT07654166
- Testing
- Tissue adhesive (PeriAcryl 90 HV), Surgical suture (Nylon 4-0)
- Where
- Syria
- Volunteers
- 28 people
- Sponsor
- Damascus University
Hemifacial Microsomia, Mucormycosis
Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.
This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects.
- Conditions
- Hemifacial Microsomia, Mucormycosis, Oral Squamous Cell Carcinoma, Microgenia
- Trial name
- 3DFACE (NCT07654647)
- Testing
- Patient-specific titanium implants for facial reconstruction
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Latakia University
Oral Lesions in Patients With Pemphigus Vulgaris
Comparison of the Efficacy of Clobetasol Propionate 0.05% Mouthwash, Photobiomodulation, and Their Combination in Managing of Oral Lesions in Patient With Pemphigus Vulgaris.
Pemphigus vulgaris (PV) is a chronic, potentially life-threatening autoimmune mucocutaneous disorder that significantly impairs patients' quality of life.
- Trial name
- NCT07641725
- Testing
- Clobetasol propionate 0.05% Mouthwash, diode laser for photobiomodulation, clobetasol propionate 0.05% mouthwash + photobiomodulation
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Helicobacter Pylori Infection, Peptic Ulcer Disease
Vonoprazan High-Dose Dual VS Levofloxacin Concomitant
This is a randomized controlled trial comparing the efficacy and safety of two vonoprazan-based regimens: high-dose dual therapy (vonoprazan plus a single antibiotic) versus triple therapy (vonoprazan plus two antibiotics) for…
- Conditions
- Helicobacter Pylori Infection, Peptic Ulcer Disease, Gastritis
- Trial name
- NCT07624422
- Testing
- Vonoprazan, Levofloxacin 500mg
- Where
- Syria
- Volunteers
- 150 people
- Sponsor
- Damascus Hospital
Bruxism, Anxiety
Bruxism, Anxiety, and Periodontal Status Among Dental Students
This observational cross-sectional study aims to evaluate the relationship between bruxism, anxiety, and periodontal status among fourth- and fifth-year dental students at Al-Hawash Private University.
- Trial name
- NCT07579416
- Where
- Syria
- Volunteers
- 100 people
- Sponsor
- Al-Hawash Private University
Periodontal Disease, Periodontal Diseases
Candida Albicans in Syrian Patients With Periodontitis
Periodontitis is a significant oral health issue characterized by inflammation and destruction of the supporting structures of the teeth.
- Conditions
- Periodontal Disease, Periodontal Diseases, Periodontitis
- Trial name
- NCT07574827
- Testing
- Periodontal Assessment and Sample Collection from Subgingival Pockets
- Where
- Syria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Hawash Private University
Primary Frontal Hyperhidrosis
Botulinum Toxin Type A for Frontal Hyperhidrosis
Frontal hyperhidrosis is a form of primary focal hyperhidrosis that significantly impairs patients' quality of life due to excessive visible sweating in the forehead region.
- Trial name
- NCT07561580
- Testing
- Botulinum Toxin Type A
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Latakia University
Gummy Smile
Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery
A gummy smile can negatively affect a patient's self-confidence and satisfaction with their appearance, leading many individuals to seek effective esthetic solutions.
- Trial name
- NCT07532161
- Testing
- Liquid Platelet-Rich Fibrin group, low-level laser group
- Where
- Syria
- Volunteers
- 22 people
- Sponsor
- Damascus University
Hyperbilirubinemia, Neonatal Indirect
The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect Hyperbilirubinemia
This is a prospective, open-label, randomized controlled trial conducted at Lattakia University Hospital (Tishreen University), aiming to evaluate the efficacy of Ursodeoxycholic Acid (UDCA) as an adjuvant to triple phototherapy…
- Trial name
- UDCA-Neo (NCT07110987)
- Testing
- Phototherapy, ursodeoxycholic acid (UDCA)
- Where
- Syria
- Volunteers
- 70 people
- Sponsor
- Tishreen University Hospital
Coronary Artery Bypass Grafting (CABG) Surgery, Myocardial Protection
Impact of Different Cardioplegia Solutions on Indicators of Myocardial Injury During Coronary Surgery
The aim of the present study is to investigate intra-operative changes in markers of myocardial injury during ischemia and reperfusion, comparing three methods of myocardial protection; St.
- Trial name
- Cardioplegia2 (NCT07358221)
- Testing
- The intervention is the use of a specific cardioplegia solution for myocardial protection
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
TTN
The Effectiveness of Inhaled Salbutamol in the Management of Transient Tachypnea of the Newborn(TTN)
TTN is the most common respiratory disorder in the perinatal period, causing 40% of cases of respiratory distress after birth. Lung fluid absorption is initiated by beta-adrenergic agonists, such as endogenous steroids and…
- Trial name
- NCT07350421
- Testing
- Salbutamol (Albuterol), Normal Saline
- Where
- Syria
- Volunteers
- 1 people
- Sponsor
- Latakia University