Clinical trials: in Reunion
Tobacco Addiction
Interventional Study on Smoking Reduction in Psychiatry
The smoking rate among people with mental disorders is higher than in the general population. Greater exposure to the harmful effects of tobacco partly explains the major inequality in life expectancy observed among people with…
- Trial name
- TABAPSY (NCT06926153)
- Testing
- TABAPSY, Usual Care
- Where
- 22 sites in France, Guadeloupe and 1 more
- Volunteers
- 6,500 people
- Sponsor
- GCS-CCOMS
Glioblastoma
Diffuse Gliomas in Reunion Island: Establishment of an Epidemiological, Clinical-biological and Socio-anthropological Cohorte
To date, very little data exists on gliomas in the Réunion population, in terms of epidemiology, socio-cultural aspects, clinical or biological factors, and care pathways.
- Trial name
- GLIORUN (NCT07865195)
- Where
- Reunion
- Volunteers
- 214 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Chikungunya Virus Infection
Real-world Effectiveness, Safety & Immunogenicity of Chikungunya Vaccination: Ambispective Study in Reunion & French Guiana
In the context of the ongoing chikungunya epidemic in Réunion Island and the anticipated epidemic in French Guiana, the investigators propose an ambispective study to evaluate the real-world effectiveness, safety, and…
- Trial name
- CHIK-RE-VAC (NCT06928753)
- Testing
- IXCHIQ, VIMKUNYA
- Where
- 2 sites in French Guiana, Reunion
- Volunteers
- 1,505 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Atopic Dermatitis, Eczema, Atopic
Dupilumab Step-down Strategy to Maintain Remission in Adult and Adolescents Patients With Atopic Dermatitis
The goal of this clinical trial is to compare a step-down strategy of spacing dupilumab injections with a standard maintenance treatment in adolescents and adults with controlled Atopic dermatitis (AD) for at least six months.
- Trial name
- MADULO (NCT05642208)
- Testing
- Dupilumab step-down
- Where
- 32 sites in France, Reunion
- Volunteers
- 256 people
- Sponsor
- Nantes University Hospital
Dermatitis
HYPNOsis in the Management of Atopic Dermatitis in Children and Teenagers
Atopic dermatitis (AD) is a chronic inflammatory dermatosis, common in children. It causes pruritus and skin lesions that can have a significant impact on patients' quality of life.
- Trial name
- HypnoDA (NCT05611346)
- Testing
- Hypnosis
- Where
- Reunion
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Heart Failure
The Value of a Simple Tool for the Early Detection of Decompensated Heart Failure in People Over 55 on Réunion Island: A Preliminary Study in Hospitals (DEPIST'IC-RUN)
The goal of this study is to assess the discriminatory power of a previously developed tool for detecting decompensated heart failure-which includes, in particular, clinical signs-in a population of patients hospitalized in…
- Trial name
- DEPIST'IC-RUN (NCT07673562)
- Testing
- Early Detection Questionnaire
- Where
- 3 sites in Reunion
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Running, Motivation for Physical Activity
Study of the Psychological, Physiological and Biomechanical Responses to Trail Running in a Hot, Humid Environment
The determinants of trail performance have been extensively studied, and the results have revealed the significant influence of physiological, psychological and biomechanical parameters.
- Conditions
- Running, Motivation for Physical Activity, Sport Physiology
- Trial name
- RP2B-Trail (NCT07831109)
- Testing
- Trail running of 28km and 2580m vertical drop
- Where
- Reunion
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Lipodystrophy, Dunnigan Syndrome
Impact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island Subjects
Few data and small numbers affect the inflammatory profile of Dunnigan patients. The levels of certain pro-inflammatory biomarkers would be found higher in these subjects compared to control individuals.
- Trial name
- LIPOKINES (NCT06107439)
- Testing
- Bood and urine sampling
- Where
- Reunion
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Diabetes type1, Diabetes Type 2
Exploration of Health Literacy in Diabetes in Reunion Island and France
The goal of this observational study is to identify the health literacy profile of diabetic patients in Reunion Island and France in order to obtain information to improve access to information, therapeutic education and to…
- Conditions
- Diabetes type1, Diabetes Type 2, Diabetes, Gestational
- Trial name
- HLQ-Diabete (NCT06437782)
- Testing
- Questionnaire completion
- Where
- 2 sites in Reunion
- Volunteers
- 1,350 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Suicide, Attempted, Suicidal Ideation
Music Against Psychological Pain in Suicide
This study compares the efficacy of music therapy associated with standard care versus the standard care alone on the psychological pain in suicidal patients.
- Trial name
- MAPPS (NCT04085848)
- Testing
- music therapy
- Where
- Reunion
- Volunteers
- 264 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Diabetes
Study of the Prevalence of Diabetes and Pre-diabetes in Réunion Island
In view of the new priority given to diabetes in Réunion and the implementation of an ambitious plan to combat the disease at regional level, which includes the identification and management of pre-diabetes, the need for…
- Trial name
- PREVADIABRUN (NCT06473584)
- Testing
- Diabetes detection
- Where
- Reunion
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pediatric Tumor
Use of Virtual Reality in Pain Management in Pediatric Oncology
DOREVI is a monocentric randomized controlled study that will evaluate the efficacy of virtual reality helmets for pain prevention during invasive care on 78 oncologic pediatric patients.
- Trial name
- DOREVI (NCT05592132)
- Testing
- Virtual reality headset
- Where
- Reunion
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Well Being
Validation of the Shared Happiness Index in Multidisciplinary Primary Care Practices ( Be aPi )
Multi-professional primary care practices (Maisons de Santé Pluriprofessionnelles, MSP) have expanded widely in France over the last decade to respond to increasing healthcare needs, uneven distribution of physicians, and…
- Trial name
- Be aPi (NCT07431372)
- Where
- Reunion
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Alzheimer s Disease, Vascular Cognitive Impairment
Adaptation of the Mini-Mental State Examination (MMSE) for the Reunion Island Population
The Mini-Mental State Examination (MMSE) is the most widely used cognitive screening and monitoring test for neurocognitive disorders in current clinical practice.
- Trial name
- MMSE-RUN (NCT07251647)
- Testing
- MMSE-RUN and MMSE GRECO
- Where
- 7 sites in Reunion
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Neurological Complication
Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements
Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring…
- Trial name
- DOPPLER (NCT05843214)
- Testing
- Non-invasive neuromonitoring evaluation (transcranial doppler, optic nerve envelope diameter and quantitative pupillometry)
- Where
- Reunion
- Volunteers
- 230 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Gene Mutation-Related Cancer, Genetic Predisposition
COsegregation of VARiants in Panel of Genes
The aim of the COVAR project is to achieve reliable classification of as many variants of interest as possible from the French OncoGenetics Database (FrOG, https://frog-db.fr/) in order to use them for the genetic counseling.
- Trial name
- COVAR (NCT01689584)
- Testing
- salivary kit
- Where
- 62 sites in France, Guadeloupe and 3 more
- Volunteers
- 11,000 people
- Sponsor
- Institut Curie
HIV Infections
Study Among People Living With HIV and Their Health Professionals of Associated Factors of Resilience to Self-stigma
This study is perform to study the effect of psychological and psychosocial factors associated with resilience to the self-stigmatization of people living with HIV
- Trial name
- RESILSTIGMA (NCT05149001)
- Where
- 43 sites in France, Guadeloupe and 1 more
- Volunteers
- 667 people
- Sponsor
- University Hospital, Clermont-Ferrand
Leptospirosis
Chronic Post-leptospirosis Manifestations in Reunion
Leptospirosis is a zoonosis caused by spirochetes, pathogenic bacteria of the genus Leptospira. It is transmitted to humans through mucocutaneous lesions by contact with water or soil contaminated by the urine of animal…
- Trial name
- LEPTONIC (NCT05436756)
- Testing
- Biological sampling and collection
- Where
- 4 sites in France, Reunion
- Volunteers
- 198 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Lipodystrophy
Assess the Possibility of Diagnosing Diabetes and Rediabetes Following Oral Induced Hyperglycemia in Patients With Dunnigan's Partial Familial Lipodystrophy by Replacing 75 g of Glucose With a Standardized Carbohydrate Breakfast and Continuous Interstitial Monitoring Glucose)
Dunnigan's syndrome is a partial familial lipodystrophy due to a mutation in the Lamine A LMNA gene. This very rare syndrome is 20 times more common in Réunion compared to the rest of Europe with several families suffering from a…
- Trial name
- HGPO-DUN (NCT05789251)
- Testing
- Standardized breakfast
- Where
- Reunion
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Contraception Behavior
SAPLAI : Assessing the faiSAbility of a Peer-to-peer Contraceptive Education Program on Social Networks Aimed at 15- to 19-year-old High School Students in GuAdeloupe and La RéunIon
The goal of this clinical trial is to evaluate the feasibility of a contraception education program delivered by peers via social networks to high school students.
- Trial name
- SAPLAI (NCT06943209)
- Testing
- Creation of a contraception education program and post on social networks for high school students, Education program, Survey and questionnaires
- Where
- 2 sites in Guadeloupe, Reunion
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion