Clinical trials: active, in Liberia
Lassa Fever
A Lassa Fever Vaccine Trial in Adults and Children Residing in West Africa
A Phase 2 Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of rVSV∆G-LASV-GPC Vaccine in Adults and Children Residing in West Africa
- Trial name
- NCT05868733
- Testing
- Day 1 Dose (2×106 pfu), Day 1 Dose (1×107 pfu), Day 1 Dose (2×10^5 pfu)
- Where
- 3 sites in Ghana, Liberia and 1 more
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
Hypertension (HTN)
Project HOPE (Hypertension Outreach Through Partnership and Engagement)
The goal of this study is to learn if a nurse-led, task-shifting, community-based program can help lower blood pressure in adults aged 25 and older with uncontrolled high blood pressure (hypertension) in Monrovia, Liberia.
- Trial name
- HOPE (NCT07681726)
- Testing
- Project HOPE Intervention
- Where
- Liberia
- Volunteers
- 150 people
- Sponsor
- Johns Hopkins University
Early Childhood Development (ECD)
Combined Nutrition and Parenting Study
This study aims to evaluate whether early childhood development is improved by a bundled set of interventions that promote responsive stimulation and improved nutrition by the provision of eggs and dried fish (nutrient-dense…
- Trial name
- BUNDLE (NCT07490899)
- Testing
- Responsive stimulation, female and male caregivers, Food provision and nutrition education
- Where
- 4 sites in Liberia
- Volunteers
- 2,240 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Hypoxemia, Morality
Health Systems and Policy Contexts of Medical Oxygen
This is a mixed-methods program evaluation from a health systems and policy perspective, involving (i) stakeholder analysis, (ii) policy-implementation gap analysis, and (iii) comparative country case studies.
- Conditions
- Hypoxemia, Morality, Pneumonia
- Trial name
- MOXY-HSP (NCT06169514)
- Testing
- No intervention
- Where
- 6 sites in Cambodia, Laos and 4 more
- Volunteers
- 1 people
- Sponsor
- Murdoch Childrens Research Institute
Lassa Fever
ISTH/ANRS 0409s INTEGRATE Lassa Fever Study
Lassa fever (LF) is a viral haemorrhagic fever responsible of 5000 deaths per year in West Africa, with in-hospital mortality at 12%.
- Trial name
- NCT06212336
- Testing
- Favipiravir, Ribavirin, Dexamethasone
- Where
- 4 sites in Liberia, Nigeria
- Volunteers
- 1,755 people
- Sponsor
- Irrua Specialist Teaching Hospital
Ebola Virus Disease
EBOla Post-Exposure Prophylaxis
EBO-PEP is a multicentre, multi-epidemic, phase III, comparative, controlled, randomised, strict superiority trial in two unblinded parallel arms.
- Trial name
- EBO-PEP (NCT06841614)
- Testing
- Ervebo, Inmazeb
- Where
- 4 sites in Democratic Republic of the Congo, Guinea and 2 more
- Volunteers
- 160 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Malaria
Community Dynamics of Malaria Transmission in Humans and Mosquitoes in Fleh-la and Marshansue, Salala District, Bong County, Liberia
Background: Malaria is a disease that affects many people in Liberia. It is caused by germs (parasites) that are spread by mosquito bites.
- Trial name
- NCT04704674
- Where
- Liberia
- Volunteers
- 396 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Onchocercal Subcutaneous Nodule, Onchocerciasis
Safety and Efficacy of Novel Combination Regimens for Treatment of Onchocerciasis
This study will investigate the safety and effectiveness of combination regimens in persons with onchocerciasis when it is administered after pre-treatment with ivermectin to clear or greatly reduce microfilariae from the skin…
- Conditions
- Onchocercal Subcutaneous Nodule, Onchocerciasis, Onchocerciasis, Ocular, Onchocerca Infection
- Trial name
- NCT06070116
- Testing
- Ivermectin w/ Albendazole, Ivermectin + Diethylcarbamazine + Albendazole, Moxidectin + Albendazole
- Where
- Liberia
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine