Clinical trials: in Egypt
Maternal and Child Health Outcomes
Oral Health Promotion vs. Standard Care in Egyptian Pregnant Women
The research question: In pregnant women, does participation in a comprehensive oral health promotion program, compared to standard care, improve maternal oral health, knowledge, attitudes, and practices? This study aims to…
- Trial name
- NCT06868550
- Testing
- Comprehensive Oral Health Promotion Program
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Necrosis, Apical Periodontitis
Conventional and Nano-Metronidazole Irrigation With/Without Activation in Necrotic Teeth With Apical Periodontitis
This randomized controlled clinical trial evaluates the effect of conventional metronidazole and nano-formulated metronidazole as root canal irrigants, with and without ultrasonic activation, in patients with necrotic…
- Trial name
- NCT07897591
- Testing
- Metronidazole 0.5%, Nano-formulated Metronidazole 0.5%, Sodium Hypochlorite 2.5%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Infraclavicular Vein Cannulation, Venous Cannulation
Right Versus Left Distal Axillary Vein Cannulation
Central venous cannulation is an essential procedure in the anaesthetic and critical care practice. Ultrasound has revolutionized the practice favoring the internal jugular cannulation to the other sites .Subcalvian vein…
- Trial name
- NCT06761326
- Testing
- Ultrasound guided right infraclavicular approach of subclavian vein cannulation, Ultrasound guided left infraclavicular approach of subclavian vein cannulation
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Alexandria University
Spinal Cord Ischemia
Risk Factors for Spinal Cord Injury After Minimally Invasive Aortic Repair
This study aims to identify factors linked to spinal cord injury after aortic repair. The aorta is the body's main artery. The repairs studied use a fabric-covered tube, called a stent graft, placed inside the aorta.
- Trial name
- SCI-AORTA (NCT07896564)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Doxorubicin Induced Cardiotoxicity, Doxorubicin Induced Cardiomyopathy
The Impact of Using Nicorandil for the Prevention of Doxorubicin-Induced Cardiotoxicity
Breast cancer is one of the world's most common cancers in females. Most of the chemotherapy protocols used to treat breast cancer involve doxorubicin. Doxorubicin has a very significant antitumor effect on breast tumors.
- Conditions
- Doxorubicin Induced Cardiotoxicity, Doxorubicin Induced Cardiomyopathy, Doxorubicin, Doxorubicin Adverse Reaction
- Trial name
- NICBREASTRCT (NCT07897409)
- Testing
- Nicorandil Oral Tablet, Adriamycin (Doxorubicin)
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Universiti Sains Malaysia
Lipedema
Aquatic Versus Land-Based Exercise in Women With Lipedema
To evaluate optimal workout environments, a 12-week study assigned women with moderate-to-severe lipedema to three distinct protocols: supervised pool workouts, equivalent land-based training, or basic standard monitoring.
- Trial name
- NCT07756463
- Testing
- aquatic therapy, land- based exercise, usual care
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Maternity Nursing, Obstetric Nursing
Enhancing Male Nursing Students' Competence in Maternity Care: A Quasi-Experimental Study in Egypt
The primary aim of this study is to evaluate the effect of structured clinical teaching scenarios on male nursing students' competence-including knowledge, self-confidence, and practical performance-in maternity care.
- Conditions
- Maternity Nursing, Obstetric Nursing, Clinical Competence, Simulation Training
- Trial name
- NCT07894419
- Testing
- Structured Scenario-Based Clinical Teaching in Maternity Care
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Cervical Plexus Block
Analgesic Efficacy of Intermediate Cervical Plexus Block in Patients Undergoing Thyroid Surgeries Using Two Bupivacaine Concentrations Non Inferiority Trial
Cervical plexus blocks (CPB) have been widely used to provide effective anesthesia and analgesia during thyroid surgeries. The ICPB was considered a good alternative to the deep CPB with an easier technique and fewer adverse…
- Trial name
- NCT06621836
- Testing
- ICPB H, ICPB - L
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Cairo University
Psoriasis, Psoriasis Genital
Efficacy of Crisaborole 2% Ointment Versus Tacrolimus 0.1% Ointment in the Treatment of Intertriginous and/or Anogenital Psoriasis.
The goal of this clinical trial is to learn if topical application of crisaborole 2% ointment can treat flexural and/or genital psoriasis in adult patients of both genders.
- Trial name
- NCT07892339
- Testing
- Crisaborole 2% topical ointment, tacrolimus ointment 0.1%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Medications in Pregnancy
Knowledge, Attitude and Perception of Pregnant Women Regarding Medications
The goal of this observational study is to learn about the pregnant women's knowledge, attitude, and perception regarding the use of medications in pregnancy.
- Trial name
- NCT06925672
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rania Hassan Mostafa
Dry Eye
20-20-20 Rule Plus Artificial Tears for Dry Eye
This study is for anyone struggling with dry, tired, or uncomfortable eyes, especially from long hours on screens. We all know that feeling after staring at a laptop or phone too long.
- Trial name
- NCT07896395
- Testing
- Artificial Tears (AT), 20/20/20 rule
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Zagazig University
Lactium, Premedication
Lactium Premedication to Prevent Emergence Agitation
This biased coin sequential allocation, dose finding study will be conducted to determine the effective dose of oral lactium in 90% of children (ED90) for prevention of emergence agitation during recovery from adenotonsillectomy.
- Conditions
- Lactium, Premedication, Emergence Agitation, Adenotonsillectomy
- Trial name
- NCT07894484
- Testing
- Lactium
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Edentulous Complete Denture Wearers
Comparison of Conventional and Face Scan in Recording the Vertical Dimension of Completely Edentulous Patients
The purpose of this study is to evaluate if a 3D face scanner is a reliable and accurate tool for measuring the vertical dimension of occlusion (the optimal height of the lower face) in patients who have lost all their teeth.
- Trial name
- NCT07898332
- Testing
- Face scan
- Where
- 2 sites in Egypt
- Volunteers
- 18 people
- Sponsor
- Ain Shams University
Radical Prostatectomy, Robotic Radical Prostatectomy
Continence Post Retzius-Sparing Versus Standard Robot-Assisted Radical Prostatectomy
To compare the short term (three month) continence rates using versius robotic system between the Retzius-sparing and the standard RARP within three month from removal of catheter.
- Conditions
- Radical Prostatectomy, Robotic Radical Prostatectomy, Retzius-sparing Robot-assisted Radical Prostatectomy With "Sandwich" Technique of Total Urethral Reconstruction
- Trial name
- Continence (NCT07899268)
- Testing
- Procedure: Retzius-Sparing Robot-Assisted Radical Prostatectomy (RS-RARP), Standard Robot-Assisted Radical Prostatectomy (S-RARP)
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Armed Forces College of Medicine, Cairo, Egypt
Dental Implant, Patient Satisfaction
Using Superimposition of Intra-Oral Scan and CBCT in Single Implant Restorations in Aesthetic Zone.
This study will be performed to evaluate patients'satisfaction and aesthetic outcomes of single implant restorations in aesthetic zone by using superimposition of intra-oral scan and CBCT.
- Trial name
- NCT05053958
- Testing
- superimposition of DICOM file from CBCT and STL file of Intraoral scanner
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Chronic Total Occlusion (CTO), Frontal QRS-T Angle
Relationship Between Frontal QRS-T Angle and Collateral Circulation in Coronary Artery Chronic Total Occlusion
Aim of the work: To examine the relationship between collateral circulation and the frontal QRS-T angle in patients with chronic total occlusion (CTO)
- Trial name
- NCT07743437
- Testing
- 12-lead Electrocardiogram (ECG) and Coronary Angiography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Healthy Participants
the Effect of Different Background Color and Skin Tone on the Accuracy of Auricular Scanning
The goal of this study is to find the best miss and match background color around an ear when taking scans for it , the investigators will recruit participants of three different skin tone and will scan their ear three times; one…
- Trial name
- NCT07108946
- Testing
- Black background, White background, Participant own skin as a background
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- yasmine Elsherbeeny
Intra-Bony Defects in Periodontitis Patients
The Efficacy of Exosomes Combined With Synthetic Bone Graft for the Treatment of Periodontal Intra-bony Defects
The aim of this study will be to evaluate clinically, radiographically and biochemically the efficacy of exosomes combined with synthetic bone graft for the treatment of periodontal intra-bony defects.
- Trial name
- NCT07897292
- Testing
- single flap approach, single flap approach combined with nanocrystalline hydroxyapatite bone substitute, Exosomes
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Khoshoe Al-mokhtar Mohammed
Dental Anxiety of Hearing Impairment
Effectiveness of Virtual Reality vs Show-Do Technique on Dental Anxiety in Children With Hearing Impairment
This randomized controlled clinical trial aims to compare the effectiveness of virtual reality (VR) eyewear used as a distraction method in combination with the Show-Do (SD) technique versus the traditional Show-Do technique…
- Trial name
- NCT07245030
- Testing
- virtual reality distraction, show-do technique
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- October University for Modern Sciences and Arts
Stage II and III Periodontitis
Effectiveness of Topical Fluoroquinolone Gel in Treating Stage II/III Periodontitis
The goal of this clinical trial is to investigate the effect of local application of levofloxacin gel on healing of periodontal pockets in patients with stage II/III periodontitis. The main questions it aims to answer are: 1.
- Trial name
- NCT07892261
- Testing
- Levofloxacin in-situ gel, Professional mechanical plaque removal
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Naira Mohammed
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