Clinical trials: completed, in Burma
Febrile Illness
Incidences, Causes, and Outcomes of Febrile Illness in Rural South and Southeast Asia
The study will collect information to understand the causes and outcomes of febrile illness in rural areas in countries across South and Southeast Asia (including Cambodia, Laos, Myanmar and Bangladesh).
- Trial name
- SEACTN-WP-A (NCT04478578)
- Where
- 7 sites in Bangladesh, Burma and 3 more
- Volunteers
- 82,760 people
- Sponsor
- University of Oxford
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon
This Clinical Evaluation Report (CER) covers the Mamba Sirolimus-Eluting PTCA Balloon catheter intended for the treatment of coronary artery disease in de novo or in-stent restenosis lesions.
- Trial name
- NCT07326735
- Testing
- Mamba Sirolimus-Eluting PTCA Balloon, Percutaneous Coronary Angioplasty with Sirolimus-Coated Balloon
- Where
- 2 sites in Burma, Malaysia
- Volunteers
- 360 people
- Sponsor
- Frisch Medical Device Private Limited
Cause of Mortality, Cause of Neonatal Death
Defining Causes of Deaths in South and Southeast Asia
Brief Summary: Mortality data are important in low and middle-income countries to assess the population health status and trends.
- Conditions
- Cause of Mortality, Cause of Neonatal Death, Cause of Child Death, Cause of Maternal Death
- Trial name
- SEACTN-VA (NCT04595656)
- Testing
- verbal autopsy interview
- Where
- 5 sites in Bangladesh, Burma and 3 more
- Volunteers
- 3,413 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hiv, Stigma, Social
Buddhist Understanding and Reduction of Myanmar Experiences of HIV Stigma and Exclusion
This project aims to explore a multi-leveled conceptualization of the effects of HIV stigma on HIV care engagement in Myanmar by conducting a mixed-method study.
- Conditions
- Hiv, Stigma, Social, Mindfulness
- Trial name
- BURMESE (NCT05126225)
- Testing
- Stigma reduction
- Where
- 2 sites in Burma, Thailand
- Volunteers
- 19 people
- Sponsor
- University of California, Los Angeles
Cardiovascular Diseases, Hypertension
Community-led Strategy to Reduce Cardiovascular Disease Risk Among Conflict-affected Populations
The goal of this study is to test a village health worker (VHW) based care model to reduce cardiovascular risk among adults in areas of eastern Myanmar affected by armed conflict.
- Conditions
- Cardiovascular Diseases, Hypertension, Diabetes
- Trial name
- NCT06819839
- Testing
- Village Health Worker (VHW) Care Model
- Where
- Burma
- Volunteers
- 213 people
- Sponsor
- Community Partners International
Tuberculosis (TB), Uveitis
Six-months Versus Nine-months ATT for Ocular TB
The goal of this clinical trial is to learn if 6-months anti-TB therapy is not worse than 9-months therapy for the treatment of tubercular posterior uveitis.
- Conditions
- Tuberculosis (TB), Uveitis, Retinal Vasculitis, Choroiditis
- Trial name
- NCT06613919
- Testing
- Anti-Tuberculosis Treatment
- Where
- 3 sites in Burma, India and 1 more
- Volunteers
- 58 people
- Sponsor
- L.V. Prasad Eye Institute
Buddhist Monks, Health Education
Health Education by Buddhist Monks to Promote Malaria Knowledge and Preventive Practices in Rural Myanmar
Malaria is still a leading public health concern in Myanmar. However, people living in rural areas usually showed poor prevention practice despite residing in malaria hotspots.
- Conditions
- Buddhist Monks, Health Education, Malaria, Monastery-based
- Trial name
- NCT06386367
- Testing
- Monastery-based health education by Buddhist monks
- Where
- Burma
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Myanmar Health Network Organization
Malaria, Bacteremia
Empirical ANtibiotic THErapy in Adults Hospitalised With Malaria
While World Health Organization (WHO) guidelines recommend empirical antibacterial therapy as the standard of care in all African children with severe falciparum malaria, there are fewer data to guide the management of adults…
- Conditions
- Malaria, Bacteremia, Sepsis
- Trial name
- ANTHEM (NCT03224052)
- Where
- Burma
- Volunteers
- 20 people
- Sponsor
- Menzies School of Health Research
Noncommunicable Disease, Infections
Rural South and Southeast Asia Household Health Survey
A cross-sectional household survey with two-stage cluster-randomized sampling. This cross-sectional household survey design to recruit a random sample of households that is representative for each of the study sites.
- Conditions
- Noncommunicable Disease, Infections, Risk Factors, Health Status
- Trial name
- SEACTN-HHS (NCT05389540)
- Where
- 4 sites in Bangladesh, Burma and 2 more
- Volunteers
- 4,747 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Tuberculosis, Multidrug-Resistant
Expand New Drugs for TB [endTB]
This observational study will examine the safety and efficacy of bedaquiline and delamanid used (individually, not together) in routine, multidrug regimens for treatment of MDR-TB.
- Trial name
- NCT03259269
- Testing
- This is a non-intervention observational study
- Where
- 16 sites in Armenia, Bangladesh and 12 more
- Volunteers
- 2,804 people
- Sponsor
- Partners in Health
Cryptococcal Meningitis
Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal Meningitis
To study the clinical effectiveness and safety of amphotericin B with flucytosine-fluconazole therapy for cryptococcal meningitis in patients with HIV infection.
- Trial name
- NCT04532463
- Testing
- Amphotericin B 1 mg/kg 1 week & Flucytosine 100 mg/kg 1 week followed by Fluconazole 1200 mg/day 1 week
- Where
- Burma
- Volunteers
- 30 people
- Sponsor
- University of Pharmacy, Yangon
HIV Infections
PrEP Among MSM and TG in Myanmar
HIV is concentrated among key populations in Myanmar. Globally, HIV-prevalence among transgender (TG) women is one of the highest; laboratory-confirmed prevalence is reported up to 40%.
- Trial name
- PrEP (NCT04781426)
- Testing
- Tenofovir Disoproxil Fumarate (TDF) 300 mg
- Where
- Burma
- Volunteers
- 200 people
- Sponsor
- Myanmar Oxford Clinical Research Unit
Malaria
Dynamics of Subclinical Malaria: Preliminary Study
This is a short longitudinal preliminary study that aims to describe the dynamics of low-density subclinical malaria to support the final study design of a subsequent matched cohort study.
- Trial name
- NCT03483571
- Where
- Burma
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Duke University
Stroke, Gait, Hemiplegic
Effect of Structured Progressive Task-Oriented Circuit Class Training With Motor Imagery on Gait in Stroke
The objectives of the study will be General Objective is to investigate the effect of TOCCT with MI on gait performance in patients with stroke. Speific Objevtives.
- Trial name
- NCT03436810
- Testing
- Motor imagery, Health education, Task-Oriented Circuit Class Training
- Where
- Burma
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Hepatitis C
Hepatitis C: Community Testing and Treatment (CT2 Study Myanmar)
Implementation-effectiveness hybrid trial assessing acceptability, feasibility and cost-effectiveness of community-based point-of-care testing and treatment for hepatitis C.
- Trial name
- CT2 (NCT03939013)
- Testing
- Xpert HCV VL
- Where
- 2 sites in Burma
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- Macfarlane Burnet Institute for Medical Research and Public Health Ltd
Plasmodium Falciparum Malaria
Targeted Chemo-elimination (TCE) of Malaria
The overall aim of this study is two fold: 1. to pilot targeted chemo-elimination of plasmodium falciparum malaria in known areas of artemisinin resistance in South East Asia. 2.
- Trial name
- TME (NCT01872702)
- Testing
- malaria elimination using DP and low-dose primaquine
- Where
- 5 sites in Burma, Cambodia and 3 more
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Drug Resistant Malaria, Asymptomatic Infections
Drug Resistance Among Asymptomatic Infection
A cross-sectional study will be conducted in selected 2 sentinel sites for assessment of drug resistance falciparum and vivax among asymptomatic infection in migrant workers in Myanmar.
- Conditions
- Drug Resistant Malaria, Asymptomatic Infections, Migrant Workers
- Trial name
- NCT03648411
- Testing
- Drug resistance molecular markers
- Where
- Burma
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Department of Medical Research, Lower Myanmar
The Prevalence of Scrub Typhus
Scrub Typhus RDT Study
Fever is one of most common presenting complaints in clinics in tropical countries. Rickettsial infections, enteric fever and leptospirosis are common and important causes of undifferentiated fever in Southeast Asia.
- Trial name
- NCT03269266
- Testing
- Scrub Typhus RDT Test
- Where
- 2 sites in Burma
- Volunteers
- 136 people
- Sponsor
- Myanmar Oxford Clinical Research Unit
Rickettsiae Infections
Rickettsiae in Myanmar
Rickettsial infections have been found to be the second most common cause of non-malarial febrile illness in Southeast Asia, just after dengue, and are largely neglected treatable causes of morbidity and mortality.
- Trial name
- Rickettsiae (NCT03847870)
- Testing
- MORU in-house ELISA test followed by IFA if positive
- Where
- Burma
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Myanmar Oxford Clinical Research Unit
Melioidosis Pneumonia
Causes of Pneumonia in Yangon
This study will evaluate a new point of care diagnostic test for the diagnosis of melioidosis pneumonia in patients attending outpatient clinics in Yangon, Myanmar
- Trial name
- NCT03578133
- Testing
- InBios® Active Melioidosis DetectTM-Lateral Flow Assay
- Where
- Burma
- Volunteers
- 300 people
- Sponsor
- Myanmar Oxford Clinical Research Unit