Clinical trials: in Bahrain
Cardiac Surgery, Cardiopulmonary Bypass
Calcium Administration in Cardiac Surgery
Termination of cardiopulmonary bypass is a critical step in any cardiac surgical procedure and requires a thorough planning. Debate about rationale of calcium administration during weaning of cardiopulmonary bypass has been…
- Trial name
- ICARUS (NCT03772990)
- Testing
- Calcium Chloride, 0.9% Sodium Chloride
- Where
- 11 sites in Bahrain, Russia and 1 more
- Volunteers
- 820 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Severe Mental Illness, Bipolar Disorder
A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness
The goal of this clinical trial is to learn whether MoodSync, a mobile application for patients and their family caregivers, improves mood stability, medication adherence, daily functioning and early detection of relapse warning…
- Conditions
- Severe Mental Illness, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder
- Trial name
- MoodSync (NCT07879131)
- Testing
- MoodSync, Standard care
- Where
- Bahrain
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Osteoarthritis (OA) of the Knee
Total Osteo-Cartilage Replacement for the Treatment of Osteoarthritis of Knee
Young patients who require total knee arthroplasty with metallic and plastic implants will undergo femoral condyle cartilage and top of the tibia with meniscus replacement.
- Trial name
- NCT07769632
- Testing
- Total osteo-cartilage replacement of the distal femur and proximal tibia, including medial and lateral meniscus., allogenic bone and cartilage graft
- Where
- Bahrain
- Volunteers
- 10 people
- Sponsor
- AlSalam Hospital
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Neoplasm Malignant Female
Supervised Exercise During Neoadjuvant Chemotherapy for Breast Cancer
The goal of this clinical trial is to learn whether supervised exercise is practical and safe for women receiving chemotherapy before surgery for breast cancer.
- Trial name
- NCT07764341
- Testing
- Supervised exercise
- Where
- Bahrain
- Volunteers
- 80 people
- Sponsor
- King Hamad University Hospital, Bahrain
Pulmonary Function, Colectomy
Effect of Arm Cycling Exercise on Pulmonary Functions After Colectomy In Elderly
This study will be done to investigate the effect of arm cycling on exercise and functional capacity, arterial blood gases, pulmonary functions, diaphragmatic excursion, time to peak inspiratory amplitude, physical function…
- Conditions
- Pulmonary Function, Colectomy, Colorectal Cancer, Post-operative Rehabilitation
- Trial name
- NCT06876961
- Testing
- Arm cycling exercise, The traditional physical therapy program
- Where
- Bahrain
- Volunteers
- 60 people
- Sponsor
- Cairo University
C.Surgical Procedure; Cardiac
Acute Normovolemic Hemodilution in High Risk Cardiac Surgery Patients.
Transfusions are one of the most overused treatments in modern medicine, and saving blood is one important issue all around the world.
- Trial name
- ANH (NCT03913481)
- Testing
- Acute normovolemic hemodilution, Standard care
- Where
- 32 sites in United States, Bahrain and 9 more
- Volunteers
- 2,000 people
- Sponsor
- Università Vita-Salute San Raffaele
Overweight and Obesity
Evaluating Weight Loss Outcomes in Patients With Overweight or Obesity
The goal of this observational study is to evaluate weight loss outcomes in adults with overweight or obesity using weight management medications.
- Trial name
- NCT07551193
- Where
- Bahrain
- Volunteers
- 300 people
- Sponsor
- Aldafter Medical Center, Bahrain
MASLD, T2DM (Type 2 Diabetes Mellitus)
Non-Invasive MASLD Diagnosis & T2D Remission Biomarkers
The goal of this observational study is to prospectively develop and validate a non-invasive scoring system based on metabolic markers, proteomic, and transcriptomic profiles to accurately screen, diagnose, stage, and monitor…
- Conditions
- MASLD, T2DM (Type 2 Diabetes Mellitus), Non-alcoholic Fatty Liver Disease (NAFLD), Obesity
- Trial name
- ENSURE-MASLD (NCT07172997)
- Testing
- Bariatric Surgery
- Where
- 2 sites in Bahrain
- Volunteers
- 163 people
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Diet, Healthy
Understanding Food Choices in Bahrain Using Bahrain e-Mart
Using a two-arm randomized controlled trial (RCT) and an intercept survey, the investigators aim to evaluate the effects of the Multiple-Traffic Light (MTL) front-of-pack (FOP) food labels in Bahrain, on diet quality of grocery…
- Trial name
- NCT06440421
- Testing
- MTL Labels
- Where
- Bahrain
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
COVID-19
A Study to Learn About the Use of Paxlovid in Patients With COVID-19 in the Kingdom of Bahrain.
The purpose of this study is to collect information on the: general information of a group of people such as their age, sex clinical information of the patients such as any other illness before having COVID 19.
- Trial name
- NCT06291831
- Testing
- nirmatrelvir, ritonavir, Controls
- Where
- Bahrain
- Volunteers
- 3,011 people
- Sponsor
- Pfizer
Diabetes Mellitus, Type 2
Movement Behaviours Among Bahraini Diabetics
This observational study aims to measure movement behaviours and explore factors influencing these among Bahraini patients with type 2 diabetes.
- Trial name
- NCT06069258
- Where
- 4 sites in Bahrain
- Volunteers
- 340 people
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Hypoglycemia
Hypoglycemia Biomarkers to Predict Timing of a Hypoglycemic Event
The study aims to obtain a panel of biomarkers from hypoglycemic diabetic patients with either type 1 or type 2 diabetics and from control patients with type 1 or type 2 diabetes who didn't have hypoglycemia in the last 72 hours.
- Trial name
- NCT06652867
- Where
- Bahrain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Sickle Cell Disease
Prospective, Observational Study in Sickle Cell Disease Patients on Crizanlizumab Treatment in Middle East Countries and India
This is a multicenter, prospective, single-arm observational non-interventional study (NIS), which will be conducted in various countries in the Middle East and India.
- Trial name
- SPOTLIGHT (NCT05020873)
- Testing
- Crizanlizumab
- Where
- 5 sites in Bahrain, Kuwait and 2 more
- Volunteers
- 44 people
- Sponsor
- Novartis Pharmaceuticals
Self-Efficacy, Self-Care
Effect of Empowerment-Based Interventions on Self-Efficacy and Self-Care Capacity Among Adults With Sickle Cell Disease
This study aimed to To investigate the effect of empowerment-based interventions (EBI) on self-efficacy and self-care capacity among adults with Sickle Cell Disease (SCD).
- Trial name
- NCT06296654
- Testing
- Empowerment-Based Interventions, Standard Health Education
- Where
- Bahrain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Bahrain
Postoperative Pain
Effect of Perioperative Oral Pregabalin in Total Knee Replacement
This interventional randomized control trial aim to determine efficacy and safety of Oral pregabalin in improving after surgery pain control in patients undergoing total knee replacement surgeries under regional anesthesia.
- Trial name
- TKR (NCT06187922)
- Testing
- Pregabalin 75mg, adductor canal block
- Where
- Bahrain
- Volunteers
- 120 people
- Sponsor
- Bahrain Defence Force Hospital
White Spot Lesion of Tooth
Remineralization Agents for the Treatment of White Spot Lesions
Clinically, formation of white spots can occur as early as 4 weeks into orthodontic treatment and very common in high caries risk individuals.
- Trial name
- NCT04827966
- Testing
- Clinpro® 5% sodium fluoride plus tri calcium phosphate varnish, Tooth Mousse® - Casein phosphopeptide-Amorphous calcium phosphate (CPP - ACP)s, MI Paste® -Casein phosphopeptide-Amorphous calcium phosphate fluoride (CPP-ACPF)
- Where
- Bahrain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bahrain
Analgesia, Pain, Postoperative
Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Prospective, randomized, case-controlled trial study. Observation post-operatively: Aims: This study aimed to compare the effectiveness of the caudal block CB with other methods of postoperative pain release.
- Conditions
- Analgesia, Pain, Postoperative, Pain, Acute
- Trial name
- paincontrol (NCT06086106)
- Testing
- caudal block, Dorsal Penile Nerve Block DPNB, Systemic opioids
- Where
- Bahrain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Sepsis, Septic Shock
Prognostic Accuracy of qSOFA, SIRS, and EWSs for In-hospital Mortality in Emergency Department
Early identification of a patient with infection who may develop sepsis is of utmost importance. Unfortunately, this remains elusive because no single clinical measure or test can reflect complex pathophysiological changes in…
- Trial name
- PASSEM (NCT05172479)
- Testing
- Measurement of qSOFA score, Measurement of SIRS criteria, Measurement of NEWS
- Where
- 20 sites in Bahrain, Kuwait and 5 more
- Volunteers
- 3,274 people
- Sponsor
- Aseer Central Hospital
Escherichia Coli Bacteremia, Klebsiella Bacteraemia
Switch to Oral Antibiotics in Gram-negative Bacteremia
Eligible subjects will be those age 18 years or more with mono-microbial blood stream infection caused by E. coli, Klebsiella species, Enterobacter species, Serratia species, Citrobacter species, or Proteus species, who have…
- Conditions
- Escherichia Coli Bacteremia, Klebsiella Bacteraemia, Enterobacter Bacteraemia, Serratia Bacteraemia
- Trial name
- SOAB (NCT04146922)
- Testing
- Step down to oral antimicrobial therapy, IV antimicrobial therapy
- Where
- 7 sites in Bahrain, Kuwait and 2 more
- Volunteers
- 176 people
- Sponsor
- Hamad Medical Corporation
COVID-19
A Study to Evaluate The Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) in Healthy Population Aged 18 Years Old and Above
This is a multicenter, randomized, double blind, parallel placebo controlled, phase 3 clinical trial to evaluate the protective efficacy, safety and immunogenicity of inactivated SARS-CoV-2 vaccines in healthy population 18 years…
- Trial name
- COVID-19 (NCT04510207)
- Testing
- Inactivated SARS-CoV-2 Vaccine (Vero cell)
- Where
- 6 sites in Bahrain, Egypt and 2 more
- Volunteers
- 44,101 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited