Clinical trials: Young Adult
Moderate to Severe Asthma
Study to Assess the Effect of Tezepelumab on the Immune Response to Influenza Vaccination in Participants With Asthma
This is a Phase 3b, multicenter, randomized, double-blind, parallel group, placebo-controlled study designed to investigate the potential effect of tezepelumab (210 mg subcutaneous [SC] every 4 weeks [Q4W]) on antibody responses…
- Trial name
- VECTOR (NCT05062759)
- Testing
- Tezepelumab
- Where
- 15 sites in United States
- Volunteers
- 70 people
- Sponsor
- AstraZeneca
Depression, Anxiety
A Randomized Controlled Trial of a VR Social Music-Movement Exergame for Depression and Anxiety in Young Adults
This randomized controlled trial aims to evaluate the effectiveness of a virtual reality (VR) music-movement exergaming intervention for improving social connectedness and psychological well-being among young adults.
- Trial name
- VR-MOVE (NCT07482852)
- Testing
- VR social musical exergame, VR solo musical exergame, Waitlist control
- Volunteers
- 130 people
- Sponsor
- Hunan University of Traditional Chinese Medicine
Forward Head Posture
The Association of Telephone Head Tilt With Cervical, Thoracic, and Lumbar Spine Mobility and Disorders in Young Adults
To determine the relationship between telephone head tilt and cervical, thoracic, and lumbar spine mobility and disturbances in young adults.
- Trial name
- NCT05814289
- Testing
- To assess telephone head tilt and cervical, thoracic, and lumbar spine mobility and disturbances.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Overweight and Obesity, Cardiometabolic Risk Factors
Effect of Vitamin K2 Over Osteocalcin, Leptin, Cytokines, and Cardiovascular Risk in Young Adults With Overweight and Obesity
The goal of this clinical trial is to compare de effect of vitamin K2 in young adults with overweight or obesity. The main questions to answer are: What is the effect of Vitamin K2 supplementation on methylation, serum…
- Trial name
- NCT05995522
- Testing
- Vitamin K2, Cornstarch
- Where
- Mexico
- Volunteers
- 51 people
- Sponsor
- University of Guadalajara
Asthma, Severe Asthma
Exploring the Lived Experience of Young Adults With Severe Asthma
Asthma is a serious long-term lung condition caused by swollen airways that narrow. This causes wheezing, chest tightness, and breathlessness. Most asthma is well-controlled with medication.
- Conditions
- Asthma, Severe Asthma, Uncontrolled Asthma
- Trial name
- EaSY (NCT06681545)
- Testing
- one to one interviews and or focus groups
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Manchester University NHS Foundation Trust
Pediatric Cancer, Adolescent and Young Adult Cancer
Improving Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention
The overarching goal is to develop and demonstrate proof-of-concept of ReSPECT (Reproductive and Sexual Health Patient Education and Communication Tool), a multi-modal communication intervention to improve adolescent and young…
- Trial name
- NCT06982066
- Testing
- ReSPECT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Connecticut Children's Medical Center
Mitochondrial Biogenesis
Examining The Effect of Blood Flow Restricted Aerobic Training on Mitochondrial Adaptations in Young Healthy Adults
This parallel-arm trial study investigates the effects of restricting arterial blood flow during cycling exercise on citrate synthase.
- Trial name
- NCT04151095
- Testing
- BFR Exercise Training, CTL Exercise Training
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brendon Gurd, PhD
Teenager, Young Adult
Cognitive Remediation Therapy in Anorexia Nervosa
"Clinicians from the Maudsley (IoP, London, UK) have specifically tailored a cognitive remediation therapy (CRT) for treating Anorexia Nervosa (AN).
- Conditions
- Teenager, Young Adult, Hospitalized, Anorexia Nervosa (DSM-IV Revised Criteria)
- Trial name
- TreCogAM (NCT01772394)
- Testing
- Cognitive Remediation Therapy
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cannabis Use Disorder
A Study of Cannabidiol in Young Adult Cannabis Users
The investigators will study the harm-reducing effect of hemp-derived CBD in non-treatment-seeking emerging adults who use cannabis regularly.
- Trial name
- NCT06569394
- Testing
- Broad Spectrum Cannabidiol (bsCBD) 400 mg
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Anemia, Sickle Cell
Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC)
The goal of this study is to specify the interventions, implementation strategies and control conditions from the Sickle Cell Disease Implementation Consortium (SCDIC) using a mixed-methods approach to study site materials and…
- Trial name
- NCT03380351
- Testing
- SCDIC interventions
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Radiation Disease
Pelvic Radiation Disease in Childhood Cancer Survivors
This study aims to characterise the impact of radiotherapy on physical symptoms and quality of life in childhood and young adult cancer survivors.
- Trial name
- NCT05533541
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Solid Tumors, Brain Tumors
Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors
Background: Cisplatin and carboplatin are standard cancer treatment drugs used for various childhood cancers, including brain tumors.
- Conditions
- Solid Tumors, Brain Tumors, Brain Metastases
- Trial name
- NCT01259479
- Testing
- Satraplatin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Cancer Institute (NCI)
Healthy Young Adults
Cognitive Embodiment Activation by tDCS
The main objective of the proposed research is to extend our understanding of how gesture and language interact, focusing on the role of cognitive embodiment in this interaction, and to explore the neural systems that support…
- Trial name
- GEST (NCT03094520)
- Testing
- tDCS
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Anorexia Nervosa
Study of Psilocybin for Anorexia in Young Adults
This is a single site trial of psilocybin therapy for the treatment of refractory Anorexia Nervosa in young adults. The psilocybin therapy will include three preparatory sessions, psilocybin dosing session one (20mg), two…
- Trial name
- SPANYA (NCT06399263)
- Testing
- Psilocybin, Preparation and Integration Sessions
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Marissa Raymond-Flesch, MD, MPH
Meningococcal Disease, Infections, Meningococcal
A Study to Evaluate 4-year Antibody Persistence and Booster Response Following MenABCWY Vaccination in Healthy Adolescents and Young Adults Who Previously Participated in Studies V102_02 (NCT01210885) and V102_02E1 (NCT01367158)
The purpose of this study is to evaluate persistence of bactericidal antibodies for N. meningitidis serogroups A, C, W, and Y and serogroup B test strains approximately 4 years after primary vaccination in subjects who previously…
- Trial name
- NCT02451514
- Testing
- MenABCWY+OMV vaccine
- Where
- 7 sites in Chile, Colombia and 1 more
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Kidney Disease, Proteinuria
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine.
- Conditions
- Chronic Kidney Disease, Proteinuria, Children
- Trial name
- FIONA OLE (NCT05457283)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 151 sites in United States, Argentina and 30 more
- Volunteers
- 100 people
- Sponsor
- Bayer
Depressive and/or Anxiety Symptoms
Meaning-centered Intervention for Internalizing Symptoms
Young adults with internalizing symptoms will be randomly assigned to a six-session meaning-centered intervention condition or a waitlist condition.
- Trial name
- NCT07058181
- Testing
- Meaning-centered intervention for individuals who tend to feel down or anxious
- Where
- Netherlands
- Volunteers
- 155 people
- Sponsor
- University of Groningen
HIV/AIDS
Peer-Educator-coordinated vs Nurse-coordinated ART Refill for Adolescents and Young Adults Living With HIV in Lesotho
Sub-Saharan Africa (SSA) is home to 85% of the adolescents and young people living with HIV (AYPLHIV) globally and they are heavily affected by the HIV/AIDS epidemic: AYPLHIV in SSA are the only population group for whom…
- Trial name
- PEBRA (NCT03969030)
- Testing
- PEBRA model
- Where
- 20 sites in Lesotho
- Volunteers
- 307 people
- Sponsor
- Amstutz Alain
Sickle Cell Disease
Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA)
This study will evaluate the acceptability, feasibility, and preliminary efficacy of a shared decision making intervention for adolescents and young adults (AYAs) with sickle cell disease (SCD).
- Trial name
- EMPOWER-AYA (NCT05383911)
- Testing
- SCD Shared Decision-Making Toolkit for AYAs - including VR, SCD Shared Decision-Making Toolkit for AYAs - without VR
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Nemours Children's Clinic
Sickle Cell Disease, Pulmonary Hypertension
Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension
The goal of this study is to test the hypothesis that hydroxyurea is effective for the specific treatment of secondary pulmonary hypertension found on screening in children and young adults with sickle cell disease.
- Trial name
- NCT00350844
- Testing
- Hydroxyurea
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
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