Clinical trials: Wrinkle Reduction
Skin Resurfacing, Wrinkle Reduction
Clinical Study to Evaluate the Performance of Fractional Radiofrequency for Improvement of Skin Texture Via Skin Resurfacing and Wrinkles Reduction
The purpose of this study is to determine whether the Matrix RF applicator is effective in the treatment of facial skin texture and wrinkle reduction.
- Trial name
- NCT00887913
- Testing
- Fractional RF treatment with Matrix RF applicator
- Where
- 3 sites in United States, Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Peri-orbital Wrinkles, Peri-oral Wrinkles
Peri-orbital and Peri-oral Wrinkle Reduction Trial
This is prospective, multi-center, single-blinded, non-randomized clinical trial. Enrolled subjects will receive two Ulthera® treatments on the peri-orbital and peri-oral regions, each treatment provided 30 days apart.
- Trial name
- NCT01981252
- Testing
- Ulthera® System Treatment
- Where
- 5 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Facelift
Evaluation of Safety and Efficacy of the Apollo™ System for Treatment of Wrinkles and Rhytides
Non-invasive, energy-based, aesthetic treatments are becoming increasingly popular among female and male patients of all ages. Different technologies are presently available to rejuvenate skin, including therapeutic ultrasound…
- Trial name
- NCT01283711
- Testing
- apollo device
- Where
- 2 sites in United States, Israel
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pollogen
Aging
Safety and Efficacy of the EndyMed Pro System Using RF Micro-needles Fractional Skin Remodeling
The need for cosmetic facial enhancement procedures with minimal down time and low risk has led to the development of methods for non-surgical skin rejuvenation.
- Trial name
- NCT02368626
- Testing
- EndyMed Pro™ RF Micro-Needles
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- EndyMed
Wrinkles
Silk'n HST for Wrinkle Reduction - Clinical Study Protocol
The objective of the study is to evaluate the safety, efficacy and usage compliance of the home-use device Silk'n HST for self-treatment of periorbital wrinkles and skin laxity and improvement of skin appearance.
- Trial name
- NCT02913547
- Testing
- Silk'n HST
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Wrinkle
BTL-785F Device for Non-invasive Reduction of Wrinkles
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05519124
- Testing
- BTL-785-7
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Rhytides, Wrinkle
Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of facial wrinkles.
- Trial name
- NCT03831477
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Photoaged Facial Skin, Photoaging
Study of RRS® HA Long Lasting for Improving Facial Wrinkles and Skin Quality
The objective of this clinical study is to confirm the clinical performance and long-term safety of the CE-marked RRS® HA Long Lasting in the treatment of skin photoaging and its consequences, with a primary focus on improving…
- Conditions
- Photoaged Facial Skin, Photoaging, Wrinkle Reduction, Skin Quality Improvement
- Trial name
- ORACLE LL (NCT07551609)
- Testing
- RRS® HA Long Lasting
- Where
- 6 sites in Spain
- Volunteers
- 207 people
- Sponsor
- Skin Tech Pharma Group S.L.U.
Wrinkle Reduction
Pivotal Study of the Cutera truSculpt Radiofrequency Device for Wrinkle Reduction
The purpose of this pivotal investigation is to evaluate the safety and efficacy of the Cutera truSculpt™ radiofrequency (RF) Device for Wrinkle Reduction.
- Trial name
- NCT03285581
- Testing
- truSculpt RF
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Unwanted Wrinkles
Evaluate the Performance of the PicoWayTM Picosecond Fractional Laser for Wrinkles Reduction
Prospective clinical study, Up to 100 healthy adult volunteers seeking Treatment of Wrinkles Reduction in the facial area, males or females of 18 to 75 years of age, from up to 5 investigational sites.
- Trial name
- NCT02600104
- Testing
- PicoWayTM
- Where
- 4 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Wrinkle Reduction
Filler Post Market Survey (FIPS)
This Post-Market Clinical Follow-Up (PMCF) survey aims to descriptively evaluate the clinical performance and safety of saypha® filler when used under routine clinical practice for the correction of moderate to severe nasolabial…
- Trial name
- FIPS (NCT07475455)
- Testing
- Hyaluronic acid dermal filler (routine clinical use)
- Where
- Austria
- Volunteers
- 33 people
- Sponsor
- Croma-Pharma GmbH
Skin Wrinkles
Study on the Safety, Efficacy of Home RF Cosmetic Instrument in the Treatment of Facial or Periorbital Wrinkles（F-MFR300-RD-003）
This is a multicenter trial with randomized control and evaluator blind method, which meets the screening criteria total of 224 subjects were enrolled and randomly divided into control group and experiment according to 1:1 ratio…
- Trial name
- NCT06565884
- Testing
- Home radiofrequency skin treatment instrument, Ultrasonic coupler for medical purposes
- Where
- China
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Flossom (GD) Beauty Technology Co., Ltd.
Wrinkle Reduction
A Prospective Pilot Study to Evaluate Safety and Effectiveness of GP0122 and GP0124 for Correction of Lines and Wrinkles in the Cheek Area
The primary objective of the study is to evaluate the safety of GP0122 and GP0124 for the correction of lines and wrinkles in the cheek area.
- Trial name
- NCT07344584
- Testing
- GP0122, GP0124
- Where
- 5 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Skin Texture Irregularities, Facial Skin Wrinkles
Safety & Efficacy Evaluation of a Radiofrequency & Laser/Light System for Improvement of Skin Texture
Evaluate the clinical performance, safety and efficacy, of a Radiofrequency and Laser/Light based device for the treatment of facial wrinkles.
- Trial name
- NCT01597323
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Wrinkle
BTL-785F Device for Non-invasive Treatment of Wrinkles and Improvement of the Face Appearance
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524805
- Testing
- BTL-785-7 Treatment
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Wrinkle
BTL-785F Device for Non-invasive Reduction of Wrinkles and Overall Facial Improvement
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524779
- Testing
- BTL-785-7
- Where
- 5 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Wrinkle, Facial and Neck Skin Laxity
Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity
A pilot study is designed to evaluate safety and efficacy of the Micro-Coring (MC) technology for treatment of facial wrinkles. MC device employs hollow coring needles that enable safe, rapid, and effective full-thickness small…
- Trial name
- NCT03228641
- Testing
- micro-excisional skin removal with coring needle
- Where
- 6 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation
DMAE Oleate for Facial Skin Firmness and Fine Lines in Healthy Adults
This single-arm, cosmetic study will evaluate the efficacy of topical DMAE Oleate on facial skin firmness and lines/wrinkles in healthy adults.
- Conditions
- Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation, Skin Laxity
- Trial name
- NCT07255560
- Testing
- Topical DMAE Oleate
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Wrinkle
Evaluation of Safety and Efficacy of the BTL-785F Device for Non-invasive Reduction of Wrinkles
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with BTL-785-2 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT04447963
- Testing
- Non-invasive treatment of facial wrinkles
- Where
- Bulgaria
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Facial Wrinkles and Rhytides Reduction
Cream Short-term Efficacy Clinical Study
This study aimed to evaluate the short-term efficacy of a facial cream (Formula# 899675 44A) on improving various skin quality and wrinkle parameters after a single application.
- Trial name
- NCT07067086
- Testing
- Test Cream
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ChinaNorm