Clinical trials: Wounds and Injury
Spinal Cord Injury
Preventing Pneumonia and Other Respiratory Problems in Persons With Spinal Cord Injury
It is known that individuals with spinal cord injury are at increased risk for respiratory tract infections like pneumonia. Part of this risk is due to weakened chest and abdominal muscles that are vital to deep breathing and the…
- Trial name
- NCT00448045
- Testing
- Manual and mechanical assisted cough, Incentive spirometry
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Kessler Foundation
Pelvic Fracture, Urethra Tear
Primary Urethral Realignment Versus Suprapubic Cystostomy After Pelvic Fracture Urethral Injury
Pelvic fracture urethral injuries (PFUI) occur in up to 10% of pelvic fractures. It remains controversial whether initial urethral realignment after PFUI decreases rates of urethral obstruction and the need for subsequent…
- Conditions
- Pelvic Fracture, Urethra Tear, Urethra Injury Male, Trauma
- Trial name
- NCT03195179
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Cancer, Hepatocellular, Radiotherapy Side Effect
A Pilot Study For Patients Receiving Radiation Therapy for Liver Cancer
The purpose of this study is to evaluate the role of quantitative MR imaging and blood-based biomarkers to measure liver function in patients receiving radiation therapy for liver cancer or cancer that has spread to the liver.
- Trial name
- HepQuant (NCT06144827)
- Testing
- Multiparametric MRI scans, Multiparametric MRI scans + HepQuantShunt Test
- Sponsor
- Montefiore Medical Center
Ischemia, Blood Circulation Disorder
Early Discovery of Ischemia After Replantation Surgery of the Extremities
Investigators will test if changes in CO2 is detected postoperatively in ischemic tissue in a replanted extremity of a traumatically amputated upper or lower extremity.
- Conditions
- Ischemia, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- EDIR (NCT05297266)
- Testing
- IscAlert
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Shoulder Impingement Syndrome, Adhesive Capsulitis
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM)
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM) is a limited lateral approach to the shoulder arthroscopically guided.
- Conditions
- Shoulder Impingement Syndrome, Adhesive Capsulitis, Rotator Cuff Tear, Hill-Sachs Lesion
- Trial name
- HLSSM (NCT05897866)
- Testing
- Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management
- Where
- Syria
- Volunteers
- 44 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.
Trauma
Rotational Thromboelastometry Activated Transfusion In Trauma Trial
This is a randomized controlled trial to compare viscoelastic (VE) guided resuscitation to fixed-ratio resuscitation in trauma patients with hemorrhagic shock on the utilization of blood products, effects on coagulation and…
- Trial name
- ROTATE-IT (NCT03765866)
- Testing
- Thromboelastometry guided transfusion
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Texas Southwestern Medical Center
TBI (Traumatic Brain Injury)
Brain Development in Young Children Following Mild Traumatic Brain Injury - Pilot Study
Concussions (also known as mild traumatic brain injury) are common in young children. In some children, they can lead to short- and long-term difficulties.
- Trial name
- KAOUENN (NCT06024122)
- Testing
- IRM exam
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Tibial Plateau Fracture
Predictors of Fracture-Dislocation in Schatzker IV Tibial Plateau Fractures: A Reproducible, Quantitative MRI-Based Injury-Pattern Analysis
This retrospective observational case-control study aims to evaluate imaging features and associated soft-tissue injury patterns in patients with Schatzker type IV tibial plateau fractures.
- Trial name
- fracture (NCT07481929)
- Testing
- Is it dislocation?
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury (TBI)
Memantine as an Additive Therapy in Patients With Traumatic Brain Injury
Memantine has shown promise in mitigating secondary brain injury in previous studies. One study demonstrated that early memantine administration in moderate TBI patients resulted in lower serum neuron-specific enolase levels and…
- Trial name
- NCT06914310
- Testing
- Memantine, Mannitol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Brain Injuries, Brain Diseases
Treating Chronic Symptoms of Pediatric Acquired Brain Injury - a Feasibility Study
Children with acquired brain injury (ABI) often struggle with complex impairments, including cognitive (such as memory and attention), social, emotional and behavioral challenges.
- Conditions
- Brain Injuries, Brain Diseases, Family, Child
- Trial name
- CICI (NCT04186182)
- Testing
- CICI - Feasibility trial study group
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Concussion, Mild
Australian UCSF Concussion in Athletes
Analysis of cardiac induced brain forces using cranial accelerometry has been shown to diagnose concussion in high school athletes.
- Trial name
- AUSSIE-1 (NCT05769296)
- Testing
- Headpulse measurements
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Hip Fractures, Elderly
Patient Reported Experience Measures Following Hip Fracture Surgery in the Elderly
With an ageing population, hip fractures are likely to become a significant public health burden. Hip fracture surgery is associated with significant morbidity and mortality.
- Conditions
- Hip Fractures, Elderly, Emergency Surgery
- Trial name
- NCT02842996
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Wounds and Injuries
Long-term Evaluation of Patients Treated by an Emergency Medical Helicopter
In May 2010 the first danish physician-staffed Helicopter Emergency Medical Service (PS-HEMS) was implemented in Region Zealand and the Capital Region (excluding Bornholm) of Denmark.
- Trial name
- NCT02175862
- Where
- Denmark
- Volunteers
- 1,791 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Shoulder Impingement Syndrome, Pain
Graded Motor Imagery Training in Shoulder Impingement Syndrome
The aim of this study is to investigate the effects of Graded Motor Imagery (GMI) training on pain, functionality, disability and daily living activities in patients diagnosed with Shoulder Impingement Syndrome.
- Trial name
- NCT06081088
- Testing
- Graded Motor Imagery (GMI) training, Conventional Physiotherapy, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Osteoporosis, Treatment Failure
Incidence of the Treatment faIlure in Osteoporosis
Osteoporotic fractures are associated with significant morbidity, increased mortality and reduction in the quality of life, available treatments reduces the fracture risk between 30 and 70%, however some patients experience a new…
- Trial name
- TAILOR (NCT05499403)
- Where
- Switzerland
- Volunteers
- 415 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Spinal Cord Injuries, Spinal Cord Diseases
Stimulation With Wire Leads to Restore Cough
The purpose of this trial is to determine the efficacy of spinal cord stimulation, using wire leads, to produce an effective cough in patients with spinal cord injuries.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases
- Trial name
- NCT01659541
- Testing
- Expiratory muscle stimulator, Implantation of device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- MetroHealth Medical Center
Shoulder Pain, Shoulder Impingement Syndrome
Shoulder Impingement Syndrome and Graded Motor Imagery
Graded motor imagery (GMI): used successfully in chronic, complex and painful clinical conditions accompanied by many pain and movement problems; It is a treatment, education and rehabilitation process that is based on recently…
- Trial name
- NCT06092502
- Testing
- Graded Motor Imagery, Traditional Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Nuray Alaca
Spinal Cord Injuries, Cardiovascular Diseases
Cardioprotective Benefit of Passive Heat Therapy in Higher-Level Spinal Cord Injury: Safety and Proof of Concept
As compared to the general population, those living with a spinal cord injury (SCI) are at a greater risk of cardiovascular (CV) diseases.The investigators know that regular exercise can help lessen the risk of CV diseases.
- Conditions
- Spinal Cord Injuries, Cardiovascular Diseases, Health Behaviour, Physical Inactivity
- Trial name
- NCT06027502
- Testing
- Passive Heating
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Intravenous Infiltration, Extravasation of Diagnostic and Therapeutic Materials
Optical Detection of Intravenous Infiltration
The purpose of this study is to investigate the safety and efficacy of an optical device designed and developed for monitoring the intravenous infusion site for infiltration.
- Trial name
- NCT01126710
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- CW Optics, Inc.
Spinal Cord Injuries (SCI), Postural Balance
Postural Control Mechanism During a Stationary Wheelchair Wheelie
The purpose of this study was to investigate the postural control during a stationary wheelchair wheelie. A group of participants was recruited for this observational study.
- Trial name
- PCWW (NCT07738913)
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
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