Clinical trials: Wounds, Closure
Laparotomy Closure After Abdominal Surgery, Suture Materials
Comparison of Vicryl Versus Prolene for Midline Rectus Sheath Closure After Elective Laparotomy
This randomized controlled trial compared two commonly used suture materials, Prolene and Vicryl, for closing the midline rectus sheath after elective laparotomy.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Suture Materials, Complications Wounds
- Trial name
- NCT07451990
- Testing
- Vicryl (Polyglactin 910) Suture, Prolene (Polypropylene) Suture
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Hayatabad Medical Complex
Cyst of Face, Neck or Shoulder, Pilomatrixoma of Face, Neck or Shoulder
Clinical Trial Comparing Tissue Adhesive Vs. Absorbable Suture Vs. Non-Absorbable Suture
Standard suture is superior to both tissue adhesive (2-octyl cyanoacrylate) and absorbable sutures with respect to cosmetic outcome of, complication rate of and parental satisfaction with the closure of low tension facial, neck…
- Trial name
- NCT00292513
- Testing
- standard suture (5-0 prolene), topical skin adhesive (dermabond), absorbable suture (5-0 Chromic gut)
- Where
- United States
- Sponsor
- Rady Children's Hospital, San Diego
Wounds and Injuries, Lacerations
A Clinical Study to Compare MAR-CUTIS With Dermabond Advanced
This was a randomized, open-label, multicenter, comparator-controlled clinical study to compare MAR-CUTIS with Dermabond Advanced in closure of surgical incisions and lacerations less than or equal to (<=)15 centimeter (cm).
- Conditions
- Wounds and Injuries, Lacerations, Surgical Incision
- Trial name
- NCT03688880
- Testing
- MAR-CUTIS, Dermabond Advanced
- Where
- 19 sites in France, Germany and 2 more
- Volunteers
- 107 people
- Sponsor
- Grünenthal GmbH
Fistula-in-ano, Draining Wound
A Study Of Cryptoglandular Fistula-in-ano And Associated Non-healing Draining Wounds With Kerecis SurgiClose
The purpose of this study is to determine feasibility of Kerecis intact fish skin for healing of fistula-in-ano and associated non-healing draining wounds.
- Trial name
- NCT07098715
- Testing
- Kerecis fish skin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Surgical Wound Infection, Wound; Abdomen, Abdominal Wall
Surgical Site Infection Rate After Intra-Abdominal Surgery Using Negative Pressure Wound Therapy at Initial Closure
The goal of this study is to present a large single-institution experience reporting surgical site infection rates in patients who have undergone intra-abdominal surgery followed by wound closure with Negative Pressure Wound…
- Conditions
- Surgical Wound Infection, Wound; Abdomen, Abdominal Wall, Surgery
- Trial name
- NCT01924884
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Johns Hopkins University
Incision, Surgical
Orthopaedic Surgical Wound Closure Comparison Study
This study is trying to find out if there is one method of surgical incision closure is better than another. The three different wound closure methods in this study are currently used in standard of care.
- Trial name
- NCT05251064
- Testing
- Suture, Clozex, Zipline
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Virginia
Wound; Knee
The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty
The STRATAFIX (Ethicon, Johnson and Johnson, Somerville, New Jersey) Knotless Tissue Control suture device is a barbed suture that uses anchor technology to securely engage with the soft tissues while also eliminating the need…
- Trial name
- NCT03285529
- Testing
- STRATIFIX, VICRYL
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Full Thickness Skin Defects
The Safety of a Novel Acellular Dermal Template as Treatment for Burns and Scars
In this study the safety and feasibility of an acellular dermal template (Novomaix), combined with split thickness skin grafts, for use in patients with full thickness skin defects, is tested.
- Trial name
- NCT02164760
- Testing
- Novomaix dermal substitute in combination with STSG
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 13 people
- Sponsor
- Association of Dutch Burn Centres
Surgical Wound
AMBULATE: Cardiva Mid-Bore VVCS vs. Manual Compression for Multiple Femoral Venous Access Sites, 6 - 12F ID
The objective of the trial is to demonstrate the safety and effectiveness of the Cardiva Mid-Bore Venous Vascular Closure System (VVCS) in sealing femoral venous access sites and providing reduced times to ambulation (TTA)…
- Trial name
- NCT03193021
- Testing
- Cardiva Mid-Bore VVCS, Manual compression
- Where
- 13 sites in United States
- Volunteers
- 204 people
- Sponsor
- Cardiva Medical, Inc.
Cesarean Section; Complications, Wound, Infection (Following Delivery)
Patient Reported Experiences and Outcomes Associated with Standard C-Section Wound Closure Versus STRATAFIX/DERMABOND PRINEO Wound Closure (CS-PREO)
The aim of the study is to compare outcomes between patients receiving standard C-section wound closure compared to a wound closure bundle that includes Stratafix sutures and Dermabond PRINEO.
- Trial name
- CS-PREO (NCT06614829)
- Testing
- Stratafix Suture, DERMABOND PRINEO
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- North York General Hospital
Mechanical Ventilation Complication, Neurological Disorder
The Cerebral-Respiratory Interaction in Controlled Mechanically Ventilated Neurosurgical Patients. (The CeRes-CMV Study)
The impact of mechanical ventilation on intracranial perfusion is still not completely clarified. It is often assumed that raising airway pressure will invariably elevate the intracranial pressure, but this is not always the…
- Conditions
- Mechanical Ventilation Complication, Neurological Disorder, Lung Injury
- Trial name
- CeRes-CMV (NCT05363085)
- Testing
- Mechanically ventilated neurosurgical patients
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Wound Healing Disorder, Impaired Wound Healing
Treatment Study of Vacuum Assisted Closure for Postsurgical Subcutaneous Abdominal Wound Healing Impairments
This clinical study is performed in several German, Dutch and Belgian hospitals to evaluate the efficacy of Vacuum Assisted Closure® (V.A.C.®) for the treatment of postsurgical abdominal wound healing impairments after surgery.
- Conditions
- Wound Healing Disorder, Impaired Wound Healing, Abdominal Wound Healing Disorder, Abdominal Wound Healing Impairment
- Trial name
- SAWHI (NCT01528033)
- Testing
- Vacuum Assisted Closure®, Standard conventional wound therapy
- Where
- 15 sites in Belgium, Germany
- Volunteers
- 539 people
- Sponsor
- University of Witten/Herdecke
Traumatic Facial Wounds
Photobiomodulation Therapy for Scar Quality After Facial Wound Closure
This study is a prospective pilot randomized controlled trial designed to evaluate the effect of photobiomodulation therapy (PBMT) on scar quality following traumatic facial wound closure.
- Trial name
- PBMT-SCAR (NCT07523204)
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- Iraq
- Volunteers
- 36 people
- Sponsor
- Hani M. Al-Kufi
Inexpensive Closure of Fasciotomy Incisions Without the Need for Skin Grafting
Dermotaxis v/s Loop Suture Technique for Closure of Fasciotomy Wounds : a Study of 50 Cases
The fasciotomy incisions lead to large, unsightly, chronic wounds after surgical intervention. The classic management was split thickness skin grafting but it leads to insensate skin with 23% of people upset by the appearance of…
- Trial name
- NCT02956733
- Testing
- dermotaxis, loop suture technique
- Volunteers
- 50 people
- Sponsor
- Government Medical College, Patiala
Surgical Wound, Wound Heal
Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects
The purpose of this study is to determine the potential influence of sun protection on the aesthetic outcome of post-surgical scars following the reconstruction of Mohs micrographic surgery defects via linear repair.
- Conditions
- Surgical Wound, Wound Heal, Wound of Skin, Scar
- Trial name
- NCT05074238
- Testing
- Zinc containing suncreen
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Surgical Site Infection, Pancreatic Neoplasms
Comparison Between Wound Vacuum Dressing and Standard Closure to Reduce Rates of Surgical Site Infections
Pancreaticoduodenectomy is associated with high perioperative morbidity, with surgical site infection (SSIs) being one of the most common complications.
- Conditions
- Surgical Site Infection, Pancreatic Neoplasms, Pancreatic Cancer, Chemotherapy Effects
- Trial name
- NCT03021668
- Testing
- Prevena Peel & Place Dressing, Standard Closure of the Surgical Incision
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Johns Hopkins University
Dural Defect, Cerebrospinal Fluid Leak
Immiseal™ Dural Sealant Post-Market Registry Study
This is a multicentre, prospective, open-label, single-arm, observational, post-market clinical follow-up registry study designed to observe the safety and performance of the Immiseal™ Dural Sealant System when used as an adjunct…
- Conditions
- Dural Defect, Cerebrospinal Fluid Leak, Neurosurgical Procedures
- Trial name
- NCT07651826
- Where
- Latvia
- Volunteers
- 85 people
- Sponsor
- Medprin Regenerative Medical Technologies Co., Ltd.
Surgical Wound, Shoulder Arthritis
Dermabond PRINEO for Total Shoulder Arthroplasty
This is a research study to find out whether wound closure (the process of closing the surgical wound after the procedure is complete) with Dermabond PRINEO Skin Closure System (PRINEO) will be faster and improve wound healing…
- Conditions
- Surgical Wound, Shoulder Arthritis, Surgical Incision
- Trial name
- NCT03860181
- Testing
- Subcuticular Sutures - Surgeon 1, Metal Staples - Surgeon 2, PRINEO - Surgeon 1
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Medical University of South Carolina
Surgical Wound
AMBULATE Continued Access Protocol to Evaluate the Cardiva Mid-Bore Venous Vascular Closure System (VVCS)
The objective of the trial is to demonstrate the safety and effectiveness of the Cardiva Mid-Bore Venous Vascular Closure System (VVCS) in sealing femoral venous access sites at the completion of catheter-based procedures…
- Trial name
- NCT03573206
- Testing
- Cardiva Mid-Bore Venous Vascular Closure Device (VVCS)
- Where
- 3 sites in United States
- Volunteers
- 168 people
- Sponsor
- Cardiva Medical, Inc.
Burns
Oleogel-S10 Versus Standard of Care in Healing of Grade 2a Burn Wounds
The main goal of this phase III clinical trial is to show safety and efficacy of Oleogel-S10 in the acceleration of wound healing of grade 2a burn wounds.
- Trial name
- NCT01657292
- Testing
- Oleogel-S10 ointment, Octenilin® wound gel
- Where
- 9 sites in Germany, Sweden and 2 more
- Volunteers
- 61 people
- Sponsor
- Birken AG