Clinical trials: Wound Care
Acute Kidney Injury
Frailty and Outcomes in Critically Ill Patients Receiving CRRT
This nationwide observational cohort study will investigate the association between frailty, chronological age, and clinical outcomes in critically ill patients receiving continuous renal replacement therapy (CRRT) in Sweden.
- Trial name
- CRRT-AF (NCT07837219)
- Volunteers
- 22,000 people
- Sponsor
- Karolinska Institutet
Hypertension
The Effect of Antihypertensive Medication Timing on Morbidity and Mortality
High blood pressure is common and its presence increases the risk of cardiovascular mortality and morbidity (most notably stroke, myocardial infarction, and congestive heart failure).
- Trial name
- NCT02990663
- Testing
- Use of blood pressure lowering medication at bedtime, Use of blood pressure lowering medication in the morning
- Where
- 5 sites in Canada
- Volunteers
- 3,357 people
- Sponsor
- University of Alberta
Acute Kidney Injury
Role of Some Biochemical Indices for Prediction of Acute Kidney Injury in Intensive Care Unit Patients in Upper Egypt
1. We will investigate the relation between the triglyceride-glucose index and the development of AKI in ICU. 2. To detect whether the TGI is a predictor of poor outcome (requirement of renal replacement therapy, or 14-day…
- Trial name
- NCT06791200
- Testing
- biochemical indices
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Kidney Injury, Fluid Overload
Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury
Critically ill patients with acute kidney injury and fluid overload who are frequently treated by fluid removal during dialysis are at an increased risk of complications and death.
- Conditions
- Acute Kidney Injury, Fluid Overload, Hypotension, Dialysis; Complications
- Trial name
- RELIEVE-AKI (NCT05306964)
- Testing
- Restrictive UFnet Rate Strategy, Liberal UFnet Rate Strategy
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- University of Pittsburgh
Hemodialysis
HEMOTOL: Efficacy and Safety of Hemodialysis On-line Monitoring Devices on Hemodynamic Stability in Intensive Care Unit
The purpose of this randomized controlled study is to compare the effects of different new dialysis on-line monitoring devices on hemodynamic stability during intermittent hemodialysis in critically ill patients with acute kidney…
- Trial name
- HEMOTOL (NCT00811109)
- Testing
- Standard Hemodialysis, with Blood Volume Management (BVM®) only, with Blood Volume (BVM®) and Temperature (BTM®) on-line monitoring
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Caen
Perinatal Mental Health
The Development of PATH, a Program to Support NICU Parent Mental Health Through the Transition From Hospital to Home
The objective of this study is to develop and pilot test a telehealth-based mental health screening and engagement program that supports parents as their infants transition home from the NICU.
- Trial name
- NCT06467916
- Testing
- Behavioral Treatment
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Colorado, Denver
Hepatitis C
HCV Post-Exposure Prophylaxis for Health Care Workers
This is an unblinded, observational trial of sofosbuvir-velpatasvir in adult health care workers who are exposed to hepatitis C virus from needlestick injury with hollow-bore needles.
- Trial name
- NCT03313414
- Testing
- Sofosbuvir/Velpatasvir Treatment for 14 days
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Intervention-carbon Monoxide Alarm + Educational Tool, Control- Usual Care Flyer on Carbon Monoxide
Emergency Department Brief Intervention to Increase Carbon Monoxide Detector Use
Carbon Monoxide (CO) exposure kills and injures thousands of children and families each year. Although there is growing concern about the need to increase carbon monoxide detector use, little is known about how best to do so…
- Trial name
- ProjectCODE (NCT00959478)
- Testing
- Educational Tool & Carbon Monoxide Alarm
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lara McKenzie
Injury, Spinal Cord
Study of Probable Benefit of the Neuro-Spinal Scaffold™ in Subjects With Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
This is a randomized, controlled, single-blind, multicenter, two Arm (Treatment or "Scaffold" Arm; Standard of Care or "Comparator" Arm) of a Neuro-Spinal Scaffold to evaluate whether the Scaffold is safe and demonstrates…
- Trial name
- INSPIRE 2 (NCT03762655)
- Testing
- Neuro-Spinal Scaffold
- Where
- 16 sites in United States
- Volunteers
- 20 people
- Sponsor
- InVivo Therapeutics
Trauma Injury, Acute Coronary Syndrome
Smart Glasses in Emergency Medicine From the Hangzhou Asian Games
The findings of our study will reveal that using smart glasses in the emergency department(ED) could facilitate patient admission. AR Smart Glasses offer the potential to enhance the effectiveness and speed of treatment within ED.
- Conditions
- Trauma Injury, Acute Coronary Syndrome, Stroke, Acute, Septic Shock
- Trial name
- SGINHZAG (NCT06623825)
- Testing
- teleconsultation by Augmented Reality smart glasses, teleconsultation by two-way radio connection.
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Sir Run Run Shaw Hospital
Perineal Injury, Pain
Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial
The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain.
- Trial name
- NCT06393608
- Testing
- Epsom salt, Water
- Where
- 4 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Antoine Roger
Arthroplasty, Replacement, Hip
Effect of Video Education on Daily Life Quality and Wound Care in Total Hip Arthroplasty Patients
This study was conducted to examine the effects of video-based education on the activities of daily living, wound healing and prosthesis dislocation of patients who had total hip replacement surgery.
- Trial name
- NCT06523829
- Testing
- GROUP GIVEN VIDEO TRAINING
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bandırma Onyedi Eylül University
Trauma
Improvement of Trauma Care Quality by Implement Trauma Register in a Middle Income Country
Every year more people die from traumatic injuries than from infections such as malaria, tuberculosis, and HIV/AIDS. About 3000 people are killed annually on Kenyan roads.
- Trial name
- NCT03485573
- Where
- Kenya
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Linkoeping
Orthopedic Patients
Telemedicine and Face-to-face Consultations Diagnostic Accuracy Comparison in Orthopedic Patients
Adult patients with acute complaints related to the musculoskeletal system are prevalent and correspond to a large percentage of visits to Emergency Care Units (UPA), often performed by general practitioners.
- Trial name
- NCT04981002
- Testing
- Telemedicine Consultation with self orthopedic exam, Face-to-face Consultation
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Israelita Albert Einstein
Multiple Trauma/Injuries
Predictors of Mortality in Multiple Trauma Patients
Trauma is a public health concern that causes serious financial and medical burdens worldwide. According to the World Health Organization, 4.4 million people die from traumatic injuries each year which account for about 8% of…
- Trial name
- NCT07185529
- Testing
- Data of the patients were obtained from patient observation files and hospital information system database.
- Where
- Turkey (Türkiye)
- Volunteers
- 269 people
- Sponsor
- Melike Cengiz
Proximal Humerus Fracture, Trauma
Impact of Mobile Health Technology Application on Proximal Humerus Fracture Care Practice
Proximal humerus fracture patient's upper limb complete function restoration mainly depends on patient rehabilitation exercises.
- Trial name
- NCT04572022
- Testing
- Step wise post-procedure mobile health shared rehabilitation teaching video instructions modules (as per fracture type)
- Volunteers
- 60 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Akut Kidney Injury, Renal Replacement Therapy for Acute Kidney Injury in ICU
The Role of Renal Resistive Index (RI) in Predicting Acute Kidney Injury Progression in Intensive Care Clinic
Acute kidney injury(AKI) is defined in the KDIGO guidelines as a ≥0.3 mg/dL (≥26.5 micromol/L) increase in serum creatinine in the previous 48 hours or a ≥1.5-fold increase in serum creatinine from baseline, known or presumed to…
- Trial name
- NCT06995222
- Testing
- renal resistive index with Doppler ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Gulhane Training and Research Hospital
Coronary Artery Disease, Complication of Coronary Artery Bypass Graft
Negative Pressure Dressing After Saphenous Vein Harvest
This study will test the effectiveness of negative pressure wound therapy (using the VAC Prevena device, KCI Canada Inc.) applied to the saphenous vein harvest site after Coronary Artery Bypass Grafting (CABG).
- Conditions
- Coronary Artery Disease, Complication of Coronary Artery Bypass Graft, Wound Complication
- Trial name
- NCT01698372
- Testing
- Prevena device (Group A)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Anesthesia, Sedation
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful.
- Conditions
- Anesthesia, Sedation, Monitored Anesthesia Care, Procedure
- Trial name
- MACS (NCT07022951)
- Testing
- Preoperative fasting
- Where
- United States
- Volunteers
- 1,200,000 people
- Sponsor
- Massachusetts General Hospital
Wounds and Injuries
Elimination of Odor and Treatment of Malodorous Recalcitrant Wounds by Using Supraz and PRP-FG Versus Standard of Care
The aim of this study is to eliminate the malodorous of chronic wound and increase the chance of the healing of recalcitrant wounds by using the repairing gel (supraz gel) which has the approved components in wound healing and…
- Trial name
- NCT05983302
- Testing
- Platelet-Rich Plasma-Fibrin Glue, Repairing Gel, Repairing Gel and Platelet-Rich Plasma-Fibrin Glue
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Mashhad University of Medical Sciences
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