Clinical trials: Worries
Generalized Anxiety Disorder
Comparing Different CBT Approaches in GAD
Cognitive-behavior therapy (CBT) is considered the "golden standard" psychotherapy for generalized anxiety disorder (GAD). However, it entails different approaches and blanket statements remain hard to formulate.
- Trial name
- CBTforGAD (NCT03650465)
- Testing
- Cognitive-behavioral therapy (CBT)
- Where
- Romania
- Volunteers
- 75 people
- Sponsor
- Babes-Bolyai University
Study Protocol Feasibility, Non Clinical Anxiety
Effects of Darkness Retreat: a Pilot Study
The primary goal of this pilot study is to test the feasibility and safety of a research protocol for a voluntary darkness retreat.
- Conditions
- Study Protocol Feasibility, Non Clinical Anxiety, Non Clinical Worry, Non Clinical Rumination
- Trial name
- NCT07429617
- Testing
- Darkness Retreat - Several Days of Seclusion in Complete Darkness
- Where
- 2 sites in Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Parkinson Disease, Anxiety
Learning Effective New Strategies for Worry in Parkinson's Disease
High rates of anxiety and worry has been observed in people with Parkinson's (PwP). Previous research outside of PwP has shown that individuals with anxiety have a habit of interpreting ambiguous information in a negative manner…
- Trial name
- LENS-PD (NCT04007718)
- Testing
- Interpretation bias training
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Generalized Anxiety Disorder
Worry Exposure for Generalized Anxiety Disorder
The purpose of this study is to examine the efficacy of a worry exposure intervention, a form of cognitive behavioral therapy (CBT), in comparison to a waitlist condition for the treatment of Generalized Anxiety Disorder.
- Trial name
- NCT02382224
- Testing
- Worry Exposure for GAD, 12-week Waitlist
- Where
- United States
- Sponsor
- University of Texas at Austin
Generalized Anxiety Disorder
Open Trial of an ACT Skills Group and Mobile App for Worry
This study is an open trial of acceptance and commitment therapy (ACT) groups combined with a mobile app for the treatment of Generalized Anxiety Disorder (GAD).
- Trial name
- NCT03709433
- Testing
- ACT groups and mobile app
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Utah State University
Cognitive Behaviour Therapy
A Clinical Trial of Cognitive Behavior Therapy for Depression, Stigmatization, Excessive Worries, and Emotional Management Among Women Facing Partner Violence
1. Aim to investigate the effectiveness of Cognitive Behavior Therapy for Depression, Stigmatization, Excessive Worries, and Emotional Management among Women Facing Partner Violence 2.
- Trial name
- NCT06208111
- Testing
- cognitive behavioral therapy
- Where
- Pakistan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Osteo Arthritis Knee, Worries; Pain or Disability
The Role of Rumination and Worry in Pain and Functional Limitation in Knee Osteoarthritis
Knee osteoarthritis is a common degenerative joint disease in which pain severity often does not fully correspond with radiographic disease severity.
- Conditions
- Osteo Arthritis Knee, Worries; Pain or Disability, Rumination
- Trial name
- NCT07609056
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Generalized Anxiety Disorder
Testing Beliefs About Uncertainty in the Treatment of Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is an anxiety disorder characterized by excessive and uncontrollable worry. Our research group has developed a cognitive-behavioural treatment (CBT) for GAD centered upon intolerance of…
- Trial name
- NCT01958788
- Testing
- Cognitive-Behavioural Treatment
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Concordia University, Montreal
Lung Cancer, Breast Cancer
Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)
This clinical trial studies whether a telemedicine-mobile health (mHealth) intervention, Finding Our Center Under Stress (FOCUS), improves symptom management in patients with cancer that may have spread from where it first…
- Conditions
- Lung Cancer, Breast Cancer, Prostate Cancer, Multiple Myeloma
- Trial name
- FOCUS (NCT07102212)
- Testing
- mHealth Intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Mothers
Validity and Reliability of the Baby Preparation and Worry Scale
Background: Reliable and valid measurement tools are needed to capture key components of prenatal distress, including anxiety and anxiety states that may put women and children at increased risk in the postpartum period.
- Trial name
- NCT05669937
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Mevlüde Alpaslan Arar
Depression, Anxiety, Self-Injurious Behavior
Brief App-based Mood Monitoring and Mindfulness Intervention for First-year College Students
The investigators examined whether brief, app-based interventions were helpful in alleviating mental health symptoms during the transition to college.
- Trial name
- NCT06348277
- Testing
- Mindfulness plus mood monitoring, Mood monitoring
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Lawrence University
Epilepsies Refractory
Trial of Multi-Strain Probiotic Supplementation (Hexbio®) in Malaysian Patients With Drug-Resistant Epilepsy (ProbE)
Probiotics are good, live bacteria and/or yeast, that live in our guts and causes no harm. They help in digestion and overall well-being of our gut system.
- Trial name
- ProbE (NCT07100743)
- Testing
- Probiotic Agent
- Where
- Malaysia
- Volunteers
- 78 people
- Sponsor
- National University of Malaysia
Barrett Esophagus, Barrett Esophagus Adenocarcinoma
A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer
The goal of the study is: The collection of various tissue samples (blood, biopsies and "esophageal brushes") and their analysis.
- Conditions
- Barrett Esophagus, Barrett Esophagus Adenocarcinoma, Adenocarcinoma - GEJ, Gastroenterology
- Trial name
- Endeavor-2 (NCT07455422)
- Testing
- Risk profile disclosure
- Where
- 10 sites in Belgium, Denmark and 5 more
- Volunteers
- 266 people
- Sponsor
- University Hospital, Antwerp
Excessive Worry
Brief Online Cognitive Behavioral Therapy for Indian Expatriates with Excessive Worry: a Pilot Feasibility Study
Background: Expatriates may face challenges through distance from support systems, cultural adjustments, and language barriers, which may be associated with anxiety and elevated worry, particularly in times of ongoing global…
- Trial name
- Worry-exp (NCT06609395)
- Testing
- Brief online CBT targeting excessiv worry
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Karolinska Institutet
Rumination, Worry
An Idiographic Examination of Treatment Mechanisms in Emotion Regulation Therapy
This study is an open trial designed to examine individual changes that occur before, during, and after 12 sessions of Emotion Regulation Therapy (ERT) delivered via telehealth for individuals in New York State who are…
- Conditions
- Rumination, Worry, Self-Criticism, Anxiety
- Trial name
- NCT05590741
- Testing
- Emotion Regulation Therapy via Telehealth
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Teachers College, Columbia University
Chronic Fatigue Syndrome
Exploring Worry in CFS/ME
This study will be building on the findings of Kalfas et al 2022 paper exploring the prevalence of generalised worry in patients with Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) before and after Cognitive…
- Trial name
- NCT06011135
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- King's College London
Insomnia, Depression
Sleep to Reduce Incident Depression Effectively in Peripartum
Perinatal depression (PND) is the most common complication in pregnancy and postpartum, which increases risk for adverse perinatal outcomes such as preterm birth, maternal suicidal thoughts, and impaired mother-infant bonding.
- Trial name
- STRIDE P (NCT06430333)
- Testing
- Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Henry Ford Health System
Excessive Worry
Development of a Scientifically Informed Written Exposure Procedure (The SCRIPTS Study)
Generalized anxiety disorder (GAD) is characterized by excessive and uncontrollable worry and anxiety. When people with GAD worry, they tend to think about problems and feared situations in a vague way.
- Trial name
- NCT03654625
- Testing
- Standard Written Exposure, Enhanced Written Exposure, Control Condition
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Toronto Metropolitan University
Cancer, Psychological Adjustment
Wonders & Worries: A Clinical Trial of a Psychosocial Intervention for Children Who Have a Parent With Cancer
Parental cancer can cause substantial behavioral and emotional distress in both parent and child. Parents struggle with talking with their child about their cancer and supporting the child during treatment.
- Trial name
- NCT02758639
- Testing
- Wonders & Worries Psychosocial Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas at Austin
Active tDCS, Sham tDCS
Combination of Neurostimulation and Psychotherapy to Stop Worrying
This study aims to investigate whether the combination of transcranial Direct Current Stimulation (tDCS) and cognitive-behavioral therapy (CBT) is more effective for treating repetitive negative thinking (RNT) in patients with…
- Trial name
- NCT06369532
- Testing
- Active tDCS
- Where
- Belgium
- Volunteers
- 85 people
- Sponsor
- University Hospital, Ghent