Clinical trials: Well Aging
Aging Well
Healthy Lifetime - Phase 2
HealthyLifetime (HL) is a person-centered program that enables older adults to maximize health and optimize functioning - the necessary requisite to successfully remaining independent in their preferred home setting as long as…
- Trial name
- NCT05920733
- Testing
- Nurse-led health coaching
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Michigan
Healthy Volunteers, Aging, Healthy
Intervention Program for Psychological Well-Being in Institutionalized Older Adults Through Virtual Reality
This randomized controlled trial (N = 60) evaluates the acceptability and efficacy of an immersive virtual reality (IVR) intervention designed to enhance psychological well-being in older adults without cognitive impairment…
- Trial name
- RRCE (NCT07884435)
- Testing
- Active IVR Group, Passive IVR Goup
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Francisco Antonio Nieto Escámez
Suicidal Ideation, Mental Health
Gamified Virtual Reality Exercise for Suicidal Ideation in Older Adults
This is a two-arm, parallel-group randomized controlled trial designed to evaluate the effectiveness of a gamified virtual reality (VR)-based exercise program in reducing suicidal ideation among community-dwelling older adults…
- Conditions
- Suicidal Ideation, Mental Health, Depression, Geriatric Psychiatry
- Trial name
- VR-GAME-SI (NCT07862803)
- Testing
- Gamified VR-Based Exercise Program, Conventional Exercise Program
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Islamic Azad University, Sanandaj
Mild Dementia, Aging Well
Transcranial Pulse Stimulation of the Brain
This study will investigate transcranial pulse stimulation (TPS) as a method of enhancing cognitive and neural function. The study team will apply this low intensity, magnetically pulse technology to key brain regions in a…
- Trial name
- NCT05910619
- Testing
- Neurolith Transcranial Pulse Stimulation Active
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Healthy Aging, Aging
The Effect of Reminiscence Therapy in Older Adults
This randomized controlled study examined the effects of reminiscence therapy on psychological well-being and mindfulness among community-dwelling older adults.
- Trial name
- NCT06964399
- Testing
- Reminiscence therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Sarcopenia, Healthy Aging
A Study on the Effects of Forest Therapy on Sarcopenia
Purpose: The goal of this study is to investigate the effects of an 8-week Forest Based Intervention program on muscle strength, physical performance, and psychological well-being in older women with sarcopenia.
- Trial name
- NCT07632417
- Testing
- Forest-Based Intervention Program
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- National Taiwan University Hospital
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Fall Injury, Age Problem
CatchU: A Quantitative Multisensory Falls-Assessment Study
The ability to successfully integrate information across sensory systems is a vital aspect of functioning in the real world. To date, only a few studies have investigated the clinical translational value of multisensory…
- Conditions
- Fall Injury, Age Problem, Well Aging, Sensory Disorders
- Trial name
- CatchU (NCT05544760)
- Testing
- CatchU Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Aging, Aging Well
Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX)
Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairments that compromise healthspan and quality of life.
- Trial name
- M3AX (NCT06507189)
- Testing
- Combined endurance and resistance training
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Aging, Aging Well
Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults
Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairments to compromise intrinsic capacity and healthspan.
- Conditions
- Aging, Aging Well, Healthy Aging
- Trial name
- BOOST-X (NCT07572266)
- Testing
- Nitrate enriched beetroot juice, Nitrate depleted beetroot juice, 12 week of combined exercise training
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Psychological Well Being, Healthy Volunteers
REVI Pilot Feasibility Trial in Long-Term Care
This pilot study evaluates the feasibility, safety, and acceptability of an immersive virtual reality (VR) intervention designed to promote psychological well-being in older adults living in a long-term care facility.
- Conditions
- Psychological Well Being, Healthy Volunteers, Aging, Long-Term Care
- Trial name
- REVI (NCT07742137)
- Testing
- Active IVR, Passive IVR
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Aging Well
Impact Evaluation of the Digital Connect Project for Homebound Older Adults
The goal of this study is to evaluate the impact of the Digital Connect Project on increasing functional capacity defined by the WHO-ICOPE and health-related quality of life (HRQL) among homebound older adults.
- Trial name
- NCT06217601
- Testing
- Digital intervention through Tablet
- Where
- Hong Kong
- Volunteers
- 1,024 people
- Sponsor
- The University of Hong Kong
Aging Well, Aging
The Role of Brain Lactate Metabolism in Neuroprotection During Healthy Aging
The brain's primary source of fuel is glucose. Unfortunately, the brain's ability to use glucose declines during normal aging. This decline in brain glucose metabolism makes it vulnerable to cognitive impairment and Alzheimer's…
- Trial name
- NCT07731451
- Testing
- Sodium lactate infusion, Exercise-induced hyperlactatemia
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Aging, Institutionalized Older Adults
Effects of Exercise, Cognitive Training, and Their Combination in Institutionalized Older Adults
The goal of this clinical trial is to learn if physical exercise, cognitive stimulation, or a combination of both can improve mobility, cognitive function, and psychosocial well-being in institutionalized older adults aged 65 and…
- Conditions
- Aging, Institutionalized Older Adults, Cognitive Abilities, Mobility and Independence
- Trial name
- NCT07082504
- Testing
- Physical Exercise Program, Cognitive Stimulation Program, Combined Physical Exercise and Cognitive Stimulation
- Volunteers
- 140 people
- Sponsor
- University of Salamanca
Psychological Well-being, Nursing Homes Residents
Effects of Exergaming and Autogenic Relaxation on Psychological Well-Being in Nursing Home Residents
This interventional clinical trial was conducted to evaluate the effects of Antroyun (exergaming) and autogenic relaxation techniques on psychological well-being and life engagement among older adults living in nursing homes.
- Conditions
- Psychological Well-being, Nursing Homes Residents, Aging, Exergaming
- Trial name
- NCT06965959
- Testing
- Exergaming Intervention Group, Autogenic Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Aging Well, Walking, Difficulty
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
- Conditions
- Aging Well, Walking, Difficulty, Hyperemia
- Trial name
- NCT05706181
- Testing
- Home-based leg heat therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Aging, Premature
Study of Neurological Aging Among People Living With HIV
A prospective, exposure-control cohort study of older adults living with HIV comparing the neurological status of those who have had HIV infection for a longer period of time (long HIV group) to age, gender, and community-matched…
- Trial name
- SNAP (NCT05678660)
- Where
- 3 sites in Zambia
- Volunteers
- 298 people
- Sponsor
- University of Rochester
Aging, Mild Cognitive Impairment
Enhancing Quality of Life for Older Adults With and Without Mild Cognitive Impairment (MCI) Through Social Engagement Over Video Technology
The goal of this randomized controlled trial is to rigorously assess the efficacy of an 8-week social engagement OneClick intervention.
- Conditions
- Aging, Mild Cognitive Impairment, Aging Well
- Trial name
- NCT05380180
- Testing
- OneClick Social Engagement Intervention, OneClick Social Engagement Intervention Extension
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Aging, Health Promotion
Social Prescribing Intervention for Health Promotion in Community-Dwelling Older Adults
This study evaluates the effects of a social prescribing intervention on health promotion outcomes in community-dwelling older adults.
- Conditions
- Aging, Health Promotion, Mental Health
- Trial name
- NCT07540117
- Testing
- Mindfulness Meditation and Walking-Pole Exercise
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan