Clinical trials: Vitrectomy
Endophthalmitis Following Cataract Surgery
Compare PPV With and Without Silicone Oil in Managing Postoperative Endophthalmitis
Comparing PPV with and without silicone oil in managing postoperative endophthalmitis
- Trial name
- Endopthalmitis (NCT06990607)
- Testing
- Pars plana Vitrectomy, Silicone Oil
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Nuclear Sclerotic Cataract
Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls
Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear.
- Trial name
- NCT00406263
- Testing
- Scheimpflug crystalline lens photographs
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Barnes Retina Institute
Nevus
Detection of Choroidal Nevus Cells in Vitrectomy Fluid
The purpose of this study is to determine if the investigators can detect the presence of choroidal nevi cells in the vitreous fluid of humans, as this may improve the diagnosis and classification of choroidal nevi and melanomas…
- Trial name
- NCT01324609
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Stanford University
Stage 2 or 3 Full Thickness Macular Hole
Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study
A macular hole is a fairly common problem in the retina and is an important cause of loss of central vision. The aim of this study is to determine whether, in patients with a stage 2 or 3 full thickness macular hole (FTMH)…
- Trial name
- FILMS (NCT00286507)
- Testing
- Vitrectomy, post hyaloid detachment and gas injection with or without ILM peel.
- Where
- 9 sites in Ireland, United Kingdom
- Volunteers
- 141 people
- Sponsor
- University of Aberdeen
Macular Holes, Retinal Detachment
Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery
The purpose of this study is to evaluate the effects of a structured exercise program on musculoskeletal pain of patients in face-down posture after retinal surgery.
- Trial name
- NCT04535622
- Testing
- A structured exercise
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Samsung Medical Center
Macular Disease
Standard Cut Rate 27-Gauge System Versus Ultrahigh-Speed 27-Gauge System in Macular Surgery
The purpose of this study is to compare the efficiency and safety of ultrahigh-speed cut rate 27-gauge system (27+®GA HYPERVIT® Vitrectomy Probe (Alcon Laboratories, Fort Worth, TX, USA)) and standard cut rate 27-gauge vitrectomy…
- Trial name
- NCT05497128
- Testing
- Ultrahigh-speed cut rate 27-gauge system, Standard cut rate 27-gauge system
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Bundang Hospital
Cataract, Corneal Disease
Influence of Pupillary Behavior During Eye Surgery on Morphological and Functional Outcome
Pupillary movement during eye surgery can be a challenge for eye surgeons. Despite the risk of intraocular lens damage and malpositioning due to mechanical manipulation1, iris manipulation may lead to a significant elevation of…
- Conditions
- Cataract, Corneal Disease, Vitreous Disorder
- Trial name
- NCT06160960
- Testing
- OCT Scan, Video of pupil movement, video of toric lens
- Where
- Austria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Klinikum Klagenfurt am Wörthersee
Rhegmatogenous Retinal Detachment With Grade C Proliferative Vitreoretinopathy
Comparison of Visual Outcomes of Pars Plana Vitrectomy With and Without Injection Clexane for Rhegmatogenous Retinal Detachment Proliferative Vitreoretinopathy
This interventional prospective study was conducted in the Department of Ophthalmology at Lahore General Hospital, Lahore. The study included 60 male and female patients aged 18-65 years who had rhegmatogenous retinal detachment…
- Trial name
- NCT07787377
- Testing
- Enoxaparin Sodium, Pars Plana Vitrectomy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital
Epiretinal Membranectomy
Change of Retinally-Induced Aniseikonia in Patients With Epiretinal Membrane After Vitrectomy
Epiretinal membrane is common disease, affecting 5~10 % incidence over 60 years old population. It reduce visual acuity, cause metamorphopsia.
- Trial name
- NCT01901406
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Yonsei University
Proliferative Diabetic Retinopathy
Efficacy and Safety Comparison of IVR and IVC Before Vitrectomy in Proliferative Diabetic Retinopathy
Proliferative diabetic retinopathy (PDR) is the most common causes of irreversible blindness in diabetic retinopathy (DR).Although pars plana vitrectomy (PPV) is the cornerstone for treatment of advanced PDR, related…
- Trial name
- NCT05414149
- Testing
- preoperative intravitreal injections of ranibizumab or conbercept
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Proliferative Diabetic Retinopathy, Vitrectomy
Observation of the Efficacy of Different Vitrectomy Systems to Treat Proliferative Diabetic Retinopathy
In recent years, vitrectomy has moved toward a minimally invasive vitrectomy surgery (MIV) system, which could effectively reduce the occurrence of operation complications, while reducing the time of post-operation recovery.
- Trial name
- NCT05446948
- Testing
- beveled 27G+ vitrectomy system, standard 25G+ vitrectomy system
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tianjin Medical University Eye Hospital
Epiretinal Membranes, Macular Holes
Blue-Blocking IOLs in Combined Surgery
Although commonly used in cataract surgery, the use of the blue light-filter IOLs in vitrectomy combined with cataract surgery has not been reported yet.
- Conditions
- Epiretinal Membranes, Macular Holes, Cataract
- Trial name
- NCT00537992
- Testing
- combined surgery
- Volunteers
- 60 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Proliferative Diabetic Retinopathy, Vitreous Hemorrhage
Cryoapplication Versus Anti-VEGF Before Diabetic Vitrectomy
Pars-plana vitrectomy (PPV) is the cornerstone of surgical treatment for eyes with complicated proliferative diabetic retinopathy. Anti-VEGF intravitreal injection before PPV has shown a good effect on surgical outcomes.
- Conditions
- Proliferative Diabetic Retinopathy, Vitreous Hemorrhage, Tractional Retinal Detachment
- Trial name
- NCT05514925
- Testing
- Bevacizumab Injection [Avastin], Peripheral Retinal Cryoapplication
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- Khairallah Moncef
Vitrectomy
Beveled-Tip Versus(vs) Standard-Tip Vitrectomy Probe
The purpose of this study is to compare the efficiency of the new Utravit High-Speed 10000 cpm Beveled Probe to the current standard vitrector probe- Alcon (non-beveled) Ultravit 7500 cpm.
- Trial name
- NCT04076072
- Testing
- Utravit High-Speed 10000 cpm Beveled Probe, standard vitrector probe- Alcon (non-beveled) Ultravit 7500 cpm
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Retinal Disease, Macular Retinoschisis
Pars Plana Vitrectomy Alone in the Treatment of Macular Schisis in High Myopic Eyes
High myopic schisis (HMF) has the clinical feature of separation between retinal layers. It is sometimes accompanied with foveal retinal detachment, macular lamellar hole, epiretinal membrane and vitreous retraction.
- Trial name
- NCT03586193
- Testing
- Pars plana vitrectomy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Patients With Highly Myopic Eyes
3D Visualization System for Vitreoretinal Diseases in Highly Myopic Eyes
To investigate the surgical outcomes and intraoperative parameters evaluation of 3D visualization system for vitreoretinal diseases in highly myopic eyes
- Trial name
- NCT05367193
- Testing
- pars plana vitrectomy, NGENUITY® 3D Visualization System (Alcon, TX, USA)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Cataract
Ketorolac Levels in Vitreous and Aqueous Samples From Patients Undergoing Combined Cataract and Pars Plana Vitrectomy Surgeries With and Without Intracameral Phenylephrine 1.0% / Ketorolac 0.3%
This is a clinical trial evaluating Ketorolac levels in vitreous and aqueous humor samples from patients undergoing combined cataract and pars plana vitrectomy surgeries with and without intracameral phenylephrine 1.0% /…
- Trial name
- NCT06539637
- Testing
- OMIDRIA (*Registered Product) {10.16 mg/mL (1% w/v) of phenylephrine and 2.88 mg/mL (0.3% w/v) of ketorolac}, Ketorolac Tromethamine {TORADOL} (0.5%) - Topical Eyedrop
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- DHS Consulting
Vision Disorders, Ocular Surface Disease
Optic Nerve Diameter and Intraocular Pressure Changes in Patients Undergoing Vitrectomy Under General Anesthesia
This study aimed to measure optic nerve sheath changes in the intraoperative period in patients who underwent vitrectomy surgery and to investigate the intraoperative factors that may affect this.
- Trial name
- NCT05195801
- Testing
- USG
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Comparison of 3D Visualization and Microscope for VR Surgery
Damages From Macular Grasping During Vitrectomy Comparing Traditional and 3D Microscope
Randomized, prospective, descriptive and comparative clinical study. The comparison is between a group of patients affected by macular pucker or macular hole, whose macular peeling is performed using a traditional optical…
- Trial name
- NCT05113212
- Testing
- Macular surgery with NGENUITY surgical display system, Macular surgery with standard operating microscope
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Anna Rita Daniele, MD
Epiretinal Membrane, Macular Edema
Dexamethasone Intravitreal Implant After Vitrectomy For Epiretinal Membrane
The purpose of this study is to evaluate the effect of dexamethasone intravitreal implant (Ozurdex) in combination with pars plana vitrectomy and membrane peeling for idiopathic epiretinal membrane (ERM).
- Trial name
- OZURDEX2 (NCT01410201)
- Testing
- Dexamethasone Intravitreal Implant
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Barnes Retina Institute